• 제목/요약/키워드: eIF

검색결과 3,595건 처리시간 0.035초

RINGS WITH VARIATIONS OF FLAT COVERS

  • Demirci, Yilmaz Mehmet;Turkmen, Ergul
    • 호남수학학술지
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    • 제41권4호
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    • pp.799-812
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    • 2019
  • We introduce flat e-covers of modules and define e-perfect rings as a generalization of perfect rings. We prove that a ring is right perfect if and only if it is semilocal and right e-perfect which generalizes a result due to N. Ding and J. Chen. Moreover, in the light of the fact that a ring R is right perfect if and only if flat covers of any R-module are projective covers, we study on the rings over which flat covers of modules are (generalized) locally projective covers, and obtain some characterizations of (semi) perfect, A-perfect and B-perfect rings.

An Australian Retrospective Study to Evaluate the Prognostic Role of p53 and eIF4E Cancer Markers in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC): Study Protocol

  • Singh, Jagtar;Jayaraj, Rama;Baxi, Siddhartha;Mileva, Mariana;Curtin, Justin;Thomas, Mahiban
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권8호
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    • pp.4717-4721
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    • 2013
  • Complete surgical resection of the primary tumour is a crucial predictive step for head and neck squamous cell carcinoma (HNSCC), because incomplete resection may lead to increase in the recurrence rate. Molecular cancer markers have been investigated as potential predictors of prognosis marker, to identify patients who are at high risk of local recurrence. This retrospective study aimed to determine the prognostic correlation between p53 and eIF4E expression and clinical characteristics, recurrence and overall survival. Forty eight HNSCC patients were selected between 2006 and 2009 diagnosed at the Royal Darwin Hospital, Darwin, Northern Territory, Australia. Out of 48, only those 24 with negative surgical margins with hematoxylin and eosin (HandE) were chosedn for further analysis. A total of 77 surgical margins were obtained and subsequently analysed by immunohistochemical (IHC) staining with monoclonal p53 and polyclonal eIF4E antibodies. Contingency table and ${\chi}^2$-test were used to investigate the correlation between p53 and eIF4E expression and clinical characteristics, recurrence and overall survival of the HNSCC patients. The follow up period was 74 months (range 1-74 months). The Kaplan-Meier method was used to generate recurrence and survival curves. This is a first retrospective study of Northern Territory patients, including Indigenous and non-Indigenous Australians. Molecular study of surgical margins could help to identify patients with and without clear margins after surgery and help in choice of the most appropriate adjuvant treatment for HNSCC patients.

EXTREMELY MEASURABLE SUBALGEBRAS

  • Ayyaswamy, S.K.
    • 대한수학회보
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    • 제22권1호
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    • pp.7-10
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    • 1985
  • For each a.mem.S and f.mem.m(S), denote by $l_{a}$ f(s)=f(as) for all s.mem.S. If A is a norm closed left translation invariant subalgebra of m(S) (i.e. $l_{a}$ f.mem.A whenever f.mem.A and a.mem.S) containing 1, the constant ont function on S and .phi..mem. $A^{*}$, the dual of A, then .phi. is a mean on A if .phi.(f).geq.0 for f.geq.0 and .phi.(1) = 1, .phi. is multiplicative if .phi. (fg)=.phi.(f).phi.(g) for all f, g.mem.A; .phi. is left invariant if .phi.(1sf)=.phi.(f) for all s.mem.S and f.mem.A. It is well known that the set of multiplicative means on m(S) is precisely .betha.S, the Stone-Cech compactification of S[7]. A subalgebra of m(S) is (extremely) left amenable, denoted by (ELA)LA if it is nom closed, left translation invariant containing contants and has a multiplicative left invariant mean (LIM). A semigroup S is (ELA) LA, if m(S) is (ELA)LA. A subset E.contnd.S is left thick (T. Mitchell, [4]) if for any finite subser F.contnd.S, there exists s.mem.S such that $F_{s}$ .contnd.E or equivalently, the family { $s^{-1}$ E : s.mem.S} has finite intersection property.y.

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GORENSTEIN SEQUENCES OF HIGH SOCLE DEGREES

  • Park, Jung Pil;Shin, Yong-Su
    • 대한수학회지
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    • 제59권1호
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    • pp.71-85
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    • 2022
  • In [4], the authors showed that if an h-vector (h0, h1, …, he) with h1 = 4e - 4 and hi ≤ h1 is a Gorenstein sequence, then h1 = hi for every 1 ≤ i ≤ e - 1 and e ≥ 6. In this paper, we show that if an h-vector (h0, h1, …, he) with h1 = 4e - 4, h2 = 4e - 3, and hi ≤ h2 is a Gorenstein sequence, then h2 = hi for every 2 ≤ i ≤ e - 2 and e ≥ 7. We also propose an open question that if an h-vector (h0, h1, …, he) with h1 = 4e - 4, 4e - 3 < h2 ≤ (h1)(1)|+1+1, and h2 ≤ hi is a Gorenstein sequence, then h2 = hi for every 2 ≤ i ≤ e - 2 and e ≥ 6.

INJECTIVE AND PROJECTIVE PROPERTIES OF REPRESENTATIONS OF QUIVERS WITH n EDGES

  • Park, Sangwon
    • Korean Journal of Mathematics
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    • 제16권3호
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    • pp.323-334
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    • 2008
  • We define injective and projective representations of quivers with two vertices with n arrows. In the representation of quivers we denote n edges between two vertices as ${\Rightarrow}$ and n maps as $f_1{\sim}f_n$, and $E{\oplus}E{\oplus}{\cdots}{\oplus}E$ (n times) as ${\oplus}_nE$. We show that if E is an injective left R-module, then $${\oplus}_nE{\Longrightarrow[50]^{p_1{\sim}p_n}}E$$ is an injective representation of $Q={\bullet}{\Rightarrow}{\bullet}$ where $p_i(a_1,a_2,{\cdots},a_n)=a_i,\;i{\in}\{1,2,{\cdots},n\}$. Dually we show that if $M_1{\Longrightarrow[50]^{f_1{\sim}f_n}}M_2$ is an injective representation of a quiver $Q={\bullet}{\Rightarrow}{\bullet}$ then $M_1$ and $M_2$ are injective left R-modules. We also show that if P is a projective left R-module, then $$P\Longrightarrow[50]^{i_1{\sim}i_n}{\oplus}_nP$$ is a projective representation of $Q={\bullet}{\Rightarrow}{\bullet}$ where $i_k$ is the kth injection. And if $M_1\Longrightarrow[50]^{f_1{\sim}f_n}M_2$ is an projective representation of a quiver $Q={\bullet}{\Rightarrow}{\bullet}$ then $M_1$ and $M_2$ are projective left R-modules.

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유아용 에듀테인먼트 Mon-E로봇 (An Edutainment Mon-E Robot for Young Children)

  • 김종철;김현호
    • 로봇학회논문지
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    • 제6권2호
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    • pp.147-155
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    • 2011
  • This paper presents an edutainment robot for young children. The edutainment robot called 'Mon-e' has developed by the Central R&D Laboratory at KT. The main services of the Mon-E robot are autonomous moving service, object card and story book telling service and videophone service. The RFID technology was introduced for easy interface to young children. The face of Mon-E robot is mounted with an RFID reader. The RFID tag is pasted on story book and object card. If you approach a book or an object card to the face of Mon-E, the Mon-E robot recognizes the identified code and plays its service. In autonomous moving, if the Mon-E robot meets obstacles, it moves back and turns left or right or half rotation. In videophone service, if young children approach an RFID card to the Mon-E, the Mon-E can make a call to the specific number, which is contained in the RFID card. The developed Mon-E robot has tested in real world environment and is evaluated young children and their parents. In the result of evaluation, the feeling of satisfaction was high to main services of Mon-E robot.

Mean ergodic theorem and multiplicative cocycles

  • Choe, Geon H.
    • 대한수학회보
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    • 제33권1호
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    • pp.57-64
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    • 1996
  • Let $(X, B, \mu)$ be a probability space. Then we say $\tau : X \to X$ is a measure-preserving transformation if $\mu(\tau^{-1} E) = \mu(E)$. and we call it an ergodic transformation if $\mu(\tau^{-1}E\DeltaE) = 0$ for a measurable subset E implies $\mu(E) = 0$. An equivalent definition is that constant functions are the only $\tau$-invariant functions.

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Depletion of PDCD4 Accelerates Stress Granule Assembly Through Sensitization of Stress Response Pathways

  • Kim, Jeeho;Chang, In Youb;Lee, Wooje;Ohn, Takbum
    • 통합자연과학논문집
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    • 제12권4호
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    • pp.127-132
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    • 2019
  • Programmed cell death 4 (PDCD4) is a novel tumor suppressor that function in the nucleus and the cytoplasm and appears to be involved in the regulation of transcription and translation. Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate when cells exposed to environmental stresses. Since PDCD4 has implicated in translation repression through direct interaction with eukaryotic translation initiation factor 4A (eIF4A), we here investigated if PDCD4 has a functional role in the process of SG assembly under oxidative stresses. Using immunofluorescence microscopy, we found that PDCD4 is localized to SGs under oxidative stresses. Next, we tested if knockdown of PDCD4 has an effect on the assembly of SG using PDCD4-specific siRNA. Interestingly, SG assembly was accelerated and this effect was caused by sensitization of phosphorylation of eIF2α and dephosphorylation of eIF4E binding protein (4E-BP). These results suggest that PDCD4 has an effect on SG dynamics and possibly involved in cap-dependent translation repression under stress conditions.

SOME RESULTS OF MONOMIAL IDEALS ON REGULAR SEQUENCES

  • Naghipour, Reza;Vosughian, Somayeh
    • 대한수학회보
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    • 제58권3호
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    • pp.711-720
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    • 2021
  • Let R denote a commutative noetherian ring, and let 𝐱 := x1, …, xd be an R-regular sequence. Suppose that 𝖆 denotes a monomial ideal with respect to 𝐱. The first purpose of this article is to show that 𝖆 is irreducible if and only if 𝖆 is a generalized-parametric ideal. Next, it is shown that, for any integer n ≥ 1, (x1, …, xd)n = ⋂P(f), where the intersection (irredundant) is taken over all monomials f = xe11 ⋯ xedd such that deg(f) = n - 1 and P(f) := (xe1+11, ⋯, xed+1d). The second main result of this paper shows that if 𝖖 := (𝐱) is a prime ideal of R which is contained in the Jacobson radical of R and R is 𝖖-adically complete, then 𝖆 is a parameter ideal if and only if 𝖆 is a monomial irreducible ideal and Rad(𝖆) = 𝖖. In addition, if a is generated by monomials m1, …, mr, then Rad(𝖆), the radical of a, is also monomial and Rad(𝖆) = (ω1, …, ωr), where ωi = rad(mi) for all i = 1, …, r.

DIFFERENT CHARACTERIZATIONS OF CURVATURE IN THE CONTEXT OF LIE ALGEBROIDS

  • Rabah Djabri
    • 대한수학회지
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    • 제61권5호
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    • pp.923-951
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    • 2024
  • We consider a vector bundle map F : E1 → E2 between Lie algebroids E1 and E2 over arbitrary bases M1 and M2. We associate to it different notions of curvature which we call A-curvature, Q-curvature, P-curvature, and S-curvature using the different characterizations of Lie algebroid structure, namely Lie algebroid, Q-manifold, Poisson and Schouten structures. We will see that these curvatures generalize the ordinary notion of curvature defined for a vector bundle, and we will prove that these curvatures are equivalent, in the sense that F is a morphism of Lie algebroids if and only if one (and hence all) of these curvatures is null. In particular we get as a corollary that F is a morphism of Lie algebroids if and only if the corresponding map is a morphism of Poisson manifolds (resp. Schouten supermanifolds).