Na-Ca exchange transports calcium ion either into (reverse mode Na-Ca exchange) or out of the cell (forward mode Na-Ca exchange) according to the direction of driving force produced by the changes in ratio of intra- and extra-cellular Na concentrations. Thus, Na-Ca exchange is regarded as the regulator of myocardial contraction. However, the existence of reverse mode Na-Ca exchange and its role in myocardial contraction is still questioned. Present study was performed to identify the presence of reverse mode Na-Ca exchange and its possible involvement in the regulation of myocardial contraction in rat heart. Using the left atria of rat, contraction was induced by electrical field stimulation (EFS, 0.5 msec duration and supramaximal voltage). Changing of the stimulation frequencies from resting 4 Hz to 0.4, 1 or 8 Hz caused typical negative staircase effect in twitch tension, but $^{45}Ca$ uptake showed bimodal increase. When the stimulation frequency was abruptly changed from 4 Hz to 0.4 Hz the atrial twitch tension showed three phased-enhancement, that is, the initial rapid increase (the first phase) followed by rapid decrease (the second phase) and stabilization (the third phase). $^{45}Ca$ uptake was equivalent to tension, i.e. initial significant increase in first 30 second and then decrease. Benzamil treatment abolished the first phase of increase in a dose dependent manner from $10^{-5}\;to\;3{\times}10^{-4}M.$ Bay k 8644 $(3{\times}10^{-5}M)$ treatment enhanced the inotropy induced by frequency reduction and abolished the second and third phase decreases. Benzamil treatment also suppressed the contraction stimulated by Bay K 8644. Although the contraction at 4 Hz stimulation was completely abolished by verapamil $3{\times}10^{-5}\;M$ pretreatment, the contraction reappeared as soon as the stimulation frequency was changed into 0.4 or 1 Hz and interstingly,$^{45}Ca$ uptake were significantly higher than no treatment. From these results, it is concluded that reduction of stimulation frequency causes calcium influx by the reverse mode Na-Ca exchange, resulting in initial rapid increase of twitch tension. then it turns into forward mode exchange to efflux the calcium, resulting in decrease of the twitch tension in left atria of rat.
KSCE Journal of Civil and Environmental Engineering Research
/
v.33
no.6
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pp.2493-2501
/
2013
Various schemes of transportation demand management(TDM) to discourage the use of cars and enhance public transit performance have been implemented in large cities. Nevertheless, policy effects in reducing car have not been satisfactory. Car-dependent travelers who tend to keep driving cars regardless of the change of the trip circumstances as such increase of travel time and cost according to car use or improvement of public transit service may be due to not according to utility reflecting mode-specific impedance and their own socio-economic characteristics. In this study, travelers were classified into four groups by their choice frequency of private car and public transit in unspecified multiple trip(car-dependent, car-choice, public transit-choice, public transit-dependent class). And the characteristics of each group were comparative analyzed. The results show that the group of a higher car-dependent is a higher priority on convenience and comfortability of the car when making decisions and the group of a lower of car-dependent is likely to change to public transit.
In the present study, we evaluate the sensitivity and optimal stripping voltammetry (SV) conditions of copper (Cu), which is one of the main trace heavy metals inducing the environmental contamination, using carbon nanotube (CNT) electrode. In addition, the reaction mechanism of stripping reaction of Cu is investigated. The electrochemical analyses such as squarewave stripping voltammetry (SWSV) and linear scan voltammetry (LSV) are used for the evaluations. As a result of that, the best SWSV conditions like squarewave amplitude of 15 mV, frequency of 60 Hz, deposition potential of -1.0V vs. Ag/AgCl and deposition time of 200s are determined with the measured Cu sensitivity of $1.824{\mu}A/{\mu}M$. As a driving force affecting the stripping reaction of Cu, surface reaction is more dominant one than diffusion. These results are compared with other reference results and it is confirmed that our suggested CNT electrode gives rise to better Cu sensitivity result than other references.
The On Line Electric Vehicles(OLEV) that can pick up inductive power from underground coils on driving with high efficiency have been developed this year, and is now proposed in this paper. The IPS(Inductive Power Supply) system consists of power supply inverters, power supply rails, pick up modules, and a regulator. There are 3 generations of IPS have been developed so far, and the $4^{th}$ generation IPS is being developed. The $1^{st}$ generation has been demonstrated this Feb. 27, which is equipped with mechanically auto tracking pick-up module with 1cm air gap, and showed 80% power efficiency. The $2^{nd}$ generation IPS applied to an 120kW (average)/240kW(peak) motor powered electric bus has 17cm air gap with 72% power efficiency. For the $2^{nd}$ generation IPS, the Power supply inverter has 440V, 3phase input and 200A @ 20kHz output. The test power supply rail of 240m long is segmented by 60m each, where newly developed core structure and power cable are constructed under the road covered with asphalt of 5cm thickness. The pick-up modules which consist of core, winding wire, and rectifiers are fixed to the bottom of the bus which can carry more than 40 passengers and can pick up max. 60kW. To remove parasitic component and to transfer maximum power between them resonant circuit topology is applied to the primary and secondary sides. The EMF level is below 62.5mG at 1.75m from the center of the road to meet the regulation. Several effective ways of reducing EMF levels have been developed. In addition, effective ways to solve problems related high frequency power cables buried in ground and it's proof from soil have been studied also. This development shows that the IPS system is capable of supplying enough power to the pick-up of OLEV and can reduce battery size, weight and cost, which means the IPS with OLEV is one of the best candidate for EV.
The Transactions of The Korean Institute of Electrical Engineers
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v.67
no.11
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pp.1423-1433
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2018
Recently, a permanent magnet synchronous motor of middle and small-capacity has high torque, high precision control and acceleration / deceleration characteristics. But existing control has several problems that include unpredictable disturbances and parameter changes in the high accuracy and rigidity control industry or nonlinear dynamic characteristics not considered in the driving part. In addition, in the drive method for the control of low-vibration and high-precision, the process of connecting the permanent magnet synchronous motor and the load may cause the response characteristic of the system to become very unstable, to cause vibration, and to overload the system. In order to solve these problems, various studies such as adaptive control, optimal control, robust control and artificial neural network have been actively conducted. In this paper, an incremental encoder of the permanent magnet synchronous motor is used to detect the position of the rotor. And the position of the detected rotor is used for low vibration and high precision position control. As the controller, we propose augmented state feedback control with a speed observer and first order deadbeat disturbance observer. The augmented state feedback controller performs control that the position of the rotor reaches the reference position quickly and precisely. The addition of the speed observer to this augmented state feedback controller compensates for the drop in speed response characteristics by using the previously calculated speed value for the control. The first order deadbeat disturbance observer performs control to reduce the vibration of the motor by compensating for the vibrating component or disturbance that the mechanism has. Since the deadbeat disturbance observer has a characteristic of being vulnerable to noise, it is supplemented by moving average filter method to reduce the influence of the noise. Thus, the new controller with the first order deadbeat disturbance observer can perform more robustness and precise the position control for the influence of large inertial load and natural frequency. The simulation stability and efficiency has been obtained through C language and Matlab Simulink. In addition, the experiment of actual 2.5[kW] permanent magnet synchronous motor was verified.
Objective: The purpose of this study is to determine the priority of information presentation and the effective menu type to be placed in the center of a gauge cluster display for commercial trucks and to present a set of ergonomic designs for the gauge cluster display. Background: An effective ergonomic design is specifically needed for the development of the gauge cluster display for the commercial trucks, because more diverse and heavier information is delivered to truck drivers, compared to the information to passenger car drivers. Method: First, all the information that must be shown on the commercial truck display was collected. Then, the severity, frequency of use, and display design parameters were evaluated for those information by commercial truck drivers. Next, an analysis on the information attributes and the heuristic evaluation utilizing the display design principles were carried out. According to the results, a design alternative of the main screen to be displayed was constructed by priority. A comparative analysis between the alternative and existing main screens was also conducted to see the efficacy of the designs. Lastly, we conducted an experiment for the selection of menu type. The experiment was conducted using the driving simulator with an eye-tracking device. The independent variables were four types of the menu reflecting the commercial truck characteristics such as grid type, icon type, list type, and flow type. We measured preference, total execution time, the total duration of fixation on the gauge cluster area, and the total number of fixation on the gauge cluster area as dependent variables. Results: Four types of driver convenience information and six types of driver assistance information were selected as the information to be placed primarily on the main screen of the gauge cluster. The Grid type was the most effective among the menu types. Conclusion: In this study, the information that appears on the main screen of the display, the division of the display and the design of the menu type for commercial truck drivers were suggested. Application: This study is expected to be utilized as guidelines on the ergonomic design of a gauge cluster display for commercial trucks.
The Journal of The Korea Institute of Intelligent Transport Systems
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v.15
no.5
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pp.95-107
/
2016
The axle weight of a vehicle in motion can be measured with a low-speed or high-speed weigh-in-motion (WIM). However, the axial load dynamically change depending on the vehicle's characteristics-such as the chassis or axle structure-or the characteristics of the driving environment such as road flatness. The changes in dynamic load lead to differences between the vehicle's weight measured at rest and the vehicle's weight measured in motion. For this Study, an experiment was conducted with an instrumented vehicle to analyze the range of errors caused by uncontrollable environmental factors by identifying the characteristics of the dynamic load changes of a vehicle in motion, and determine the appropriate scale for the accuracy evaluation of a high-speed WIM, as a preparatory research for the introduction of unmanned overweight enforcement systems in the future. The key findings from the experiment are summarized as follows. First, The gross weight of the tested vehicle changed by approximately 1% at low velocities and approximately by 4% at high velocities, and the vehicle's axle weight changed by approximately 1-3%, at low velocities and by 2-9% at high velocities. A single axle showed larger weight changes than individual axles in a group. Secondly, The vehicle's gross weight and the axle weight on the impact section were up to eight times and three-to-twelve times higher, respectively, than its gross weight and the axle weight on the flat section. The vibration frequency of the vehicle's dynamic load was measured at between 2.4 and 5.8Hz, and found to return to the normal amplitude after moving approximately 30 meters.
Journal of the Institute of Electronics Engineers of Korea SD
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v.46
no.2
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pp.93-100
/
2009
This paper presents a step up four channel DC-DC converter using charge pump voltage doubler structure. Our goal is to design and implement DC-DC converter for capacitive SP4T RF MEMS switch in front end module in wireless transceiver system. Charge pump structure is small and consume low power 3.3V input voltage is boosted by DC-DC Converter to $11.3{\pm}0.1V$, $12.4{\pm}0.1V$, $14.1{\pm}0.2V$ output voltage With 10MHz switching frequency. By using voltage level shifter structure, output of DC-DC converter is selected by 3.3V four channel selection signals and transferred to capacitive MEMS devices. External passive devices are not used for driving DC-DC converter. The total chip area is $2.8{\times}2.1mm^2$ including pads and the power consumption is 7.52mW, 7.82mW, 8.61mW.
The Journal of Korean Institute of Electromagnetic Engineering and Science
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v.22
no.11
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pp.1034-1046
/
2011
In this paper, a design and fabrication of 40 W power amplifier for the X-band using load-pull measurement of GaN HEMT chip are presented. The adopted active device for power amplifier is GaN HEMT chip of TriQuint company, which is recently released. Pre-matched fixtures are designed in test jig, because the impedance range of load-pull tuner is limited at measuring frequency. Essentially required 2-port S-parameters of the fixtures for extraction optimal input and output impedances is obtained by the presented newly method. The method is verified in comparison of the extracted optimal impedances with data sheet. The impedance matching circuit for power amplifier is designed based on EM co-simulation using the optimal impedances. The fabricated power amplifier with 15${\times}$17.8 $mm^2$ shows the efficiency above 35 %, the power gain of 8.7~8.3 dB and the output power of 46.7~46.3 dBm at 9~9.5 GHz with pulsed-driving width of 10 usec and duty of 10 %.
"Ubiquitous sensor network" definition is this-Someone attaches electro-magnetic tag everything which needs communication between man to man, man to material and material to material(Ubiquitous). By using attached every electro-magnetic tag, someone detects it's native information as well as environmental information such as temperature, humidity, pollution and infiltration information(Sensor). someone connects it realtime network and manage generated information(Network). 21st century's war is joint combined operation connecting with ground, sea and air smoothly in digitalized war field, and is systematic war provided realtime information from sensor to shooter. So, it needs dramatic development on watch reconnaissance, command and control, pinpoint strike etc. Ubiquitous computing and network technologies are essential in national defense to operate 21st century style war. It is possible to use many parts such as USN combined smart dust and sensor network to protect friend unit as well as to watch enemy's deep area by unmanned reconnaissance, wearable computer upgrading soldier's operational ability and combat power dramatically, RFID which can be used material management as well as on time support. Especially, unmanned watch system using USN is core part to transit network centric military service and to get national defense efficiency which overcome the dilemma of national defense person resource reducing, and upgrade guard quality level, and improve combat power by normalizing guardian's bio rhythm. According to the test result of sensor network unmanned watch system, it needs more effort and time to stabilize because of low USN technology maturity and using maturity. In the future, USN unmanned watch system project must be decided the application scope such as application area and starting point by evaluating technology maturity and using maturity. And when you decide application scope, you must consider not only short period goal as cost reduction, soldier decrease and guard power upgrade but also long period goal as advanced defense ability strength. You must build basic infra in advance such as light cable network, frequency allocation and power facility etc. First of all, it must get budget guarantee and driving force for USN unmanned watch system project related to defense policy. You must forwarded the USN project assuming posses of operation skill as procedure, system, standard, training in advance. Operational skill posses is come from step by step application strategy such as test phase, introduction phase, spread phase, stabilization phase and also repeated test application taking example project.
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