• Title/Summary/Keyword: diffusing treatment

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Therapeutic Effects of Eucalyptus Globulus Essential Oil on an Animal Model with Allergic Rhinitis (안엽유의 흡입이 알레르기성 비염 동물모델의 비염치료에 미치는 영향)

  • 구영희;최인화
    • The Journal of Korean Medicine
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    • v.25 no.1
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    • pp.40-48
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    • 2004
  • Background and Objectives: Aroma therapy using Eucalyptus Globulus essential oil for curing allergic rhinitis is an inhalation treatment which has been applied as an aid to oriental clinics which use a fundamental treatment such as acupuncture and herbs. There have been no studies so far performed on the effect of this oils' use, only . We aimed to find out the therapeutic effect of its exclusive use only on an Animal Model with Allergic Rhinitis. Materials and Methods: Sprague-Dawley rats were induced the allergic rhinitis by ovalbumin solution. And then, rats in the treated group were treated by diffusing Eucalyptus essential oil in a flask for 7 days. Compared with the treated group, rats in the control group were treated by diffusing normal saline in a flask for 7 days. We observed changes in glandular cells and mast cells in nasal mucosa and submucosa; also changes in the number of eosinophils and neutrophils in blood and the succus of rhinenchysis. Results: The number of neutrophils in the succus of rhinenchysis was significantly decreased in treated group compared with control group(p<0.05). The number of neutrophils in blood and mast cells in nasal mucosa were decreased in the treated group but, these were not significant statistically(p>0.05). Histologic changes showed edema; congestion and expansion of grandular cells in nasal submucosa and hypertrophy of epithelium in nasal mucosa were decreased in treated group compared with control group. Conclusions: The results may suggest that the inhalation treatment using Eucalyptus essential oil decreases the inflammatory response on an Animal Model with Allergic Rhinitis.

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Analysis of Wear Properties for $Ni_{3}Al$ Layer coated on Ferrous Materials by Diffusion Treatment after Combustion Synthesis at low Temperature (저온 연소합성 후 확산 열처리한 $Ni_{3}Al$ 금속간화합물 코팅층의 미끄럼 마모거동)

  • Lee, Han-Young
    • Tribology and Lubricants
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    • v.25 no.1
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    • pp.7-12
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    • 2009
  • Coating brittle intermetallic compounds on metal can enlarge the range of their use. It is found that intermetallic compound coating layers made by only combustion synthesis in an electric furnace have porous multi-phase structures containing several intermediate phases, even though the coating layers show good wear resistance. In this study, dense $Ni_{3}Al$ single phase layer corresponding to the initial composition of the mixed powder is coated on two different ferrous materials by the diffusing treatment after combustion synthesis. After- ward, sliding wear behaviors of the coating layer are evaluated in comparison with that of the coating layer with porous multi-phase structure made by only combustion synthesis. As a result, the wear properties of the coating layer composed of dense $Ni_{3}Al$ single phase are considerably improved at the range of low sliding speed com- pared with that of the coating layer with porous multi-phase structure, particularly in the running-in wear region. This is attributed to the fact that wear of the coating layer is progressed by shearing as a sequence of adhesion, not by occurring of pitting on the worn surface due to having dense structure without pores.

Study on Epidemic Warm Diseases with dampness of "OnByeongJoByeon" ("온병조변(溫病條辨)" 습류온병(濕類溫病)에 대한 고찰)

  • Park, Mi Sun;Kim, Yeong Mok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.6
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    • pp.803-811
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    • 2012
  • Oriental Medicine always attach great importance to the damp diseases. Dampness is related with many organs and many clinical diseases. The cause and the location of the damp disease, nature of the symptoms, combination with other pathogenic factors are very diverse. This article analyzed the concept, cause of disease, pathogenesis, characteristic of symptoms, treatment method and prescriptions of Epidemic Warm Diseases of dampness syndrome and cases of dampness-heat diseases based on the theories of Epidemic Warm Diseases and found that theories of Epidemic Warm Diseases have very wide area of application. Dampness is classified into cold-dampness and dampness-heat by combination of heat or cold. The dampness syndrome is related with organs such as lung, spleen, kidney, triple energizers and bladder, and affects liver and heart. The basic treatment methods are dispelling dampness turbidity and diffusing qi movement. The detail treatment methods are spreading lung qi with lightness and resolving dampness and excreting turbidity in upper energizer, opening and dipping down with pungent-bitter and diffusing qi movement and strengthening the spleen and stomach in the middle energizer, draining dampness with bland in the lower energizer. Warming Yang is the main method of treatment for cold-dampness and clearing heat is for dampness-heat with the assistant methods such as resolving dampness and promoting the flow of qi. 5. Acute fever, virus diseases, epidemic diseases among modern diseases are much related with the dampness-heat syndrome.

A Comprehensive Review of Diffusing Alpha-Emitters Radiation Therapy (DaRT): From Dosimetry to Its Biological Effectiveness

  • Seohan Kim;Wonmo Sung
    • Journal of Radiation Protection and Research
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    • v.49 no.3
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    • pp.102-113
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    • 2024
  • Diffusing alpha-emitters radiation therapy (DaRT) represents a groundbreaking development in cancer therapy, offering a solution to the limitations of conventional radiation therapy. By deploying 224Ra embedded seeds, DaRT achieves targeted delivery of high-dose alpha particles directly to tumor sites, showing considerable efficacy in tumor control and minimal damage to adjacent healthy tissues. This comprehensive review analyzes the published literature regarding mechanisms, seed production, dose calculation, measurement, and biological experiments related to DaRT. It includes in-depth discussions on mathematical models, Monte Carlo simulations for dose distribution, real-time in vivo dosimetry developments, and biological experiments both in vitro and in vivo. Clinical trial outcomes are also examined to evaluate the therapy's effectiveness in various cancer types. DaRT utilizes 224Ra-labeled seeds, using the decay chain of 224Ra to deliver alpha particles effectively within a tumor. Several asymptotic diffusion-leakage models were developed to calculate the alpha dose distribution of DaRT. In vivo dosimetry techniques have been developed for real-time monitoring. Biological experiments demonstrated the cytotoxic effects of DaRT across various cancer cells, with varying radiosensitivity. Additionally, the enhanced effects of combined therapy with chemotherapy and immunotherapy were suggested by many in vivo studies. Clinical trials have shown high complete response rate in squamous cell carcinoma, with minimal side effects, suggesting DaRT's feasibility and safety. DaRT emerges as a highly localized cancer treatment method with minimal side effects compared to traditional radiation therapy. It directly ablates tumors and potentially enhances immune responses, indicating a significant advance in cancer therapy. Future research and ongoing clinical trials will further elucidate its efficacy across different cancer types and in combination with other treatments.

Application of rapid thermal annealing process to the aluminum induced crystallization of amorphous silicon thin film (비정질 실리콘의 부분적 알루미늄 유도 결정화 공정에서의 급속 열처리 적용 가능성)

  • Hwang, Ji-Hyun;Yang, Su-Won;Kim, Young-Kwan
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.29 no.2
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    • pp.50-53
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    • 2019
  • In this study, polycrystalline silicon thin film useful for the solar cells was fabricated by AIC(Aluminum Induced Crystallization) process. A diffusing barrier for this process is prepared with $Al_2O_3$. For the maximization of the grain size of the polycrystalline silicon, a selective blasting of the $Al_2O_3$ diffusing barrier was conducted before annealing treatment. The heat treatment for the activation of the amorphous-Si (a-Si) layer was carried out with Rapid Thermal Annealing (RTA) process. Crystallization of the a-Si layer was analyzed with XRD. It was confirmed that a-Si was crystallized at $500^{\circ}C$ and the silicon crystal is observed to be formed and the grain size of the polycrystalline silicon was observed to be $15.9{\mu}m$.

Analysis of the Carburizing Heat Treatment Process for SNCM Alloy Steel Using the Finite Element Method (유한요소법을 이용한 SNCM 합금강의 침탄열처리 공정 해석)

  • Choi S.C.;Lee D.J.;Kim H.Y.;Kim H.J.
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.30 no.10 s.253
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    • pp.1284-1292
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    • 2006
  • Heat treatment is a controlled heating and cooling process to improve the physical and/or mechanical properties of metal products without changing their shapes. Today finite element method is widely used to simulate lots of manufacturing processes including heat treatment and surface hardening processes, which aims to reduce the number of time- and cost-consuming experimental tryouts. In this study we tried, using this method, to simulate the full carburizing process that consists of carburizing, diffusing and quenching, and to predict the distribution of carbon contents, phase fraction and hardness, thermal deformation and other mechanical characteristics as the results. In the finite element analysis deformation, heat transfer, phase transformation and diffusion effects are taken into consideration. The carburizing process of a lock gear, a part of the car seat recliner, that is manufactured by the fine blanking process is adopted as the analysis model. The numerical results are discussed and partly compared with experimental data. And a combination of process parameters that is expected to give the highest surface hardness is proposed on the basis of this discussion.

Crystallization of amorphous silicon films below $450^{\circ}C$ by FALC ($450^{\circ}C$ 이하에서 FALC 공정에 의한 비정질 실리콘의 결정화)

  • 박경완;유정은;최덕균
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.12 no.4
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    • pp.210-214
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    • 2002
  • The crystallization behavior of amorphous silicon (a-Si) film was investigated by using Cu-field aided lateral crystallization (Cu-FALC) process below $450^{\circ}C$. The lateral crystallization was induced from the Cu deposited region outside of pattern toward the Cu-free region inside of the pattern by applying an electric field during heat treatment. As expected, the lateral crystallization toward Cu-free region proceeded from negative toward positive electrode side. The occurrence of Cu-FALC phenomenon was interpreted in terms of dominant diffusing species in the reaction between Cu and Si. Even at the annealing temperature of $350^{\circ}C$, the large dendrite-shaped branches were formed in the crystallized region and the polarity in the lateral crystallization was clearly observed. Consequently, we could successfully crystallize the a-Si at the temperature as low as $350^{\circ}C$ by an electric field of 30 V/cm with fast crystallization velocity of 12 $\mu$m/h.

Formation of TiN by Ti Nitridation in NH3Ambient (NH3분위기에서 Ti 질화에 의한 TiN 형성)

  • 이근우;박수진;유정주;권영호;김주연;전형탁;배규식
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.17 no.2
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    • pp.150-155
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    • 2004
  • This study attempts to form a TiN barrier layer against Cu diffusion by the easier and more convenient method. In this new approach, Ti was sputter-deposited, and nitrided by heat-treating in the NH$_3$ambient. Sheet resistance of as-deposited Ti was 20 Ω/$\square$, but increased to 195 Ω/$\square$ after the heat-treatment at 30$0^{\circ}C$, and lowered to 120 Ω/$\square$ after the heat-treatment at 50$0^{\circ}C$, and $600^{\circ}C$. AES results for these thin films confirmed that the atomic ratio of Ti and N was close to 1:1 at or above 40$0^{\circ}C$ heat-treatment. However, it was also found that excessive oxygen was contained in the TiN layer. To examine the barrier property against Cu diffusion, 100nm Cu was deposited on the TiN layer and then annealed at 40$0^{\circ}C$ for 40 min.. Cu remained at the surface without diffusing into the Si layer.

Corrosion Resistance and Low Friction Property of Sintered Steel Parts via Chromizing Treatment (크로마이징 처리 된 철계 소결 부품의 내식성 및 저 마찰특성)

  • Kim, Sang-Gweon;Park, Yong-Jin;Yeo, Kuk-Hyun;Lee, Jae-Hoon
    • Korean Journal of Metals and Materials
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    • v.50 no.11
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    • pp.809-815
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    • 2012
  • Recently, as the interest in improving energy efficiency has grown, the demand for vehicle and machine parts that are resistant in high temperature corrosive conditions and abrasive environments has increased. Pack chromizing treatment of sintered steels is a profitable method that satisfies both corrosion resistance and low friction properties. Since austenitic stainless steels have good corrosion resistance but low mechanical hardness, if they are replaced by sintered steel parts with pack chromizing treatment, all the desirable properties such as low price, easy molding, high hardness, low frictional coefficient, and high corrosion resistance, can be obtained. The higher corrosion resistance of the chromized parts over that of the austenitic stainless steels was acquired by coating chromium carbides and a thin chromium oxides layer on the surface. Moreover, the surface morphology of chromized parts, which were composed of chromium rich phases and hardened chromium carbides by diffusing and alloying, had a peak-and-valley shape so that the dimple effect by the wrinkled morphology and high hardness induced a low friction coefficient.

Nucleation of CVD Diamond on Various Substrate Materials

  • Fukunaga, O.;Qiao, Xin;Ma, Yuefei;Shinoda, N.;Yui, K.;Hirai, H.;Tsurumi, T.;Ohashi, N.
    • The Korean Journal of Ceramics
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    • v.2 no.4
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    • pp.184-187
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    • 1996
  • Diamod nucleation by mw assisted CVD was examined various conditions namely, (1) diamond nucleation on variour substrate materials, such as Si, cubic BN, pyrolytic BN and AIN, (2) AST(Activated species transport) method which promote nucleation of diamond on single crystal and polycrystalline alumina substrate was developed. (3) Effect of bias enhancement of nucleation on single crystalline Si was examined, and finally (4) DST (Double step treatment) method was developed to enhance diamond nucleation on Ni. In this method, we separated carbon diffusing process into Ni, carbon precipitating process from the inside of Ni and diamond precipitation process.

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