• Title/Summary/Keyword: differential selection

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Extraction Method of Significant Clinical Tests Based on Data Discretization and Rough Set Approximation Techniques: Application to Differential Diagnosis of Cholecystitis and Cholelithiasis Diseases (데이터 이산화와 러프 근사화 기술에 기반한 중요 임상검사항목의 추출방법: 담낭 및 담석증 질환의 감별진단에의 응용)

  • Son, Chang-Sik;Kim, Min-Soo;Seo, Suk-Tae;Cho, Yun-Kyeong;Kim, Yoon-Nyun
    • Journal of Biomedical Engineering Research
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    • v.32 no.2
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    • pp.134-143
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    • 2011
  • The selection of meaningful clinical tests and its reference values from a high-dimensional clinical data with imbalanced class distribution, one class is represented by a large number of examples while the other is represented by only a few, is an important issue for differential diagnosis between similar diseases, but difficult. For this purpose, this study introduces methods based on the concepts of both discernibility matrix and function in rough set theory (RST) with two discretization approaches, equal width and frequency discretization. Here these discretization approaches are used to define the reference values for clinical tests, and the discernibility matrix and function are used to extract a subset of significant clinical tests from the translated nominal attribute values. To show its applicability in the differential diagnosis problem, we have applied it to extract the significant clinical tests and its reference values between normal (N = 351) and abnormal group (N = 101) with either cholecystitis or cholelithiasis disease. In addition, we investigated not only the selected significant clinical tests and the variations of its reference values, but also the average predictive accuracies on four evaluation criteria, i.e., accuracy, sensitivity, specificity, and geometric mean, during l0-fold cross validation. From the experimental results, we confirmed that two discretization approaches based rough set approximation methods with relative frequency give better results than those with absolute frequency, in the evaluation criteria (i.e., average geometric mean). Thus it shows that the prediction model using relative frequency can be used effectively in classification and prediction problems of the clinical data with imbalanced class distribution.

Differential Selection by Nematodes of an Introduced Biocontrol Fungus vs. Indigenous Fungi in Nonsterile Soil

  • Kim, Tae Gwan;Knudsen, Guy R.
    • Journal of Microbiology and Biotechnology
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    • v.28 no.5
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    • pp.831-838
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    • 2018
  • Trophic interactions of introduced biocontrol fungi with soil animals can be a key determinant in the fungal proliferation and activity. This study investigated the trophic interaction of an introduced biocontrol fungus with soil nematodes. The biocontrol fungus Trichoderma harzianum ThzID1-M3 and the fungivorous nematode Aphelenchoides sp. (10 per gram of soil) were added to nonsterile soil, and microbial populations were monitored for 40 days. Similar results were obtained when the experiment was duplicated. ThzID1-M3 stimulated the population growth of indigenous nematodes (p < 0.05), regardless of whether Aphelenchoides sp. was added. Without ThzID1-M3, indigenous nematodes did not increase in number and the added Aphelenchoides sp. nematodes almost disappeared by day 10. With ThzID1-M3, population growth of nematodes was rapid between 5 and 10 days after treatment. ThzID1-M3 biomass peaked on day 5, dropped at day 10, and then almost disappeared at day 20, which was not influenced by the addition of nematodes. In contrast, a large quantity of ThzID1-M3 hyphae were present in a heat-treated soil in which nematodes were eliminated. Total fungal biomass in all treatments peaked on day 5 and subsequently decreased. Addition of nematodes increased the total fungal biomass (p < 0.05), but ThzID1-M3 addition did not affect the fungal biomass. Hyphae of total fungi when homogenously distributed did not support the nematode population growth; however, hyphae of the introduced fungus did when densely localized. The results suggest that soil fungivorous nematodes are an important constraint on the hyphal proliferation of fungal agents introduced into natural soils.

University Hierarchy and Labor Market Outcome - Wage Differentials between Provincial and Seoul Metropolitan Area University Graduates - (대학서열과 노동시장 성과 - 지방대생 임금차별을 중심으로 -)

  • Oh, Hoyoung
    • Journal of Labour Economics
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    • v.30 no.2
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    • pp.87-118
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    • 2007
  • Using KRIVET's Graduates Economic Activities Survey for 2005, this article examines the relationship between university ranking and labor market outcome, with a focus on wage differentials existing between provincial and Seoul metropolitan area university graduates. According to the analysis results, the average monthly wage for provincial university graduates was 1,747.7 thousand Korean won, which is 11.5% lower than that for graduates of universities in the Seoul metropolitan area. School effects on individual wage were estimated to about 12.2% after applying Hierarchical Linear Model technique, which means that university explains only an insignificant part of the total variance in wage among graduates. After controlling for the selection bias, the ability difference between the two areas, by applying the Heckman type 2SLS wage function and Neumark wage differential decomposition technique, the wage gap resulting from the segregation was not identified. This implies that, to a significant extent, the wage gap between provincial and Seoul metropolitan university graduates is attributed to the difference in productivity among individual graduates, rather than to the wage segregation. Also, the estimated wage function by applying Quantile Regression technique indicates that there does not exist any significant wage segregation difference by wage quantile.

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Differential diagnosis of ovarian cysts and selection of therapeutic drugs in slaughtered cows (도축우 유래 난소낭종의 감별진단 및 치료제 선택)

  • 박상국;최동식;박장일;정대영
    • Korean Journal of Veterinary Service
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    • v.23 no.2
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    • pp.125-132
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    • 2000
  • To establish the differential diagnosis and treatment method in bovine ovarian cysts, specially ovarian cysts with corpus luteum, serum progesterone ($P_4$) concentration and ultrasonography for measuring the cystic wall thickness and diameter of cyst and corpus luteum were investigated from slaughtered cows with ovarian cysts. Ovarian cysts were classified 8 types by the number of cyst, cystic wall thickness and present of corpus luteum. Ovarian cysts with corpus luteum were 11 (13.6%) of 81 cows and ovarian cysts without corpus luteum were 70 (86.4%) cows. The incidence rates of 8 various types of ovarian cysts were as follows; 2Ba 33.3%, 2Aa 25.9% and 2Bb 14.8%, respectively The Incidence rates of ovarian cysts without corpus luteum were follicular cyst 59.2% and luteal cyst 27.2%. The cystic wall thickness were 2Ab 3.7mm and 2Bb 3.5mm, and the serum P4 concentrations were above 2.0 ng/$m\ell$ in IAa, tAb, IBa, 2Ab and 2Bb, respectively In ovarian cysts with corpus luteum, the correlation coefficients between corpus luteum area and serum $P_4$ concentration were 0.45. In ovarian cysts without corpus luteum, there was significantly positive correlations between cystic wall thickness and serum $P_4$ concentration($r^2$ = 0.54, p<0.01). These results indicate that $PGF_2$$\alpha$ analogues can be choice for treatment of ovarian cysts with corpus luteum and above 3mm the cystic wall thickness because serum $P_4$ concentrations were above 2.0 ng/$m\ell$ in ovarian cysts with corpus luteum and thickened cystic wall. In conclusion, it Is suggested that ultrasonography is useful diagnostic tool for diagnosis and selection of treatment remedy in cystic ovaries of bovine.

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Non-Profiling Power Analysis Attacks Using Continuous Wavelet Transform Method (연속 웨이블릿 변환을 사용한 비프로파일링 기반 전력 분석 공격)

  • Bae, Daehyeon;Lee, Jaewook;Ha, Jaecheol
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.31 no.6
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    • pp.1127-1136
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    • 2021
  • In the field of power analysis attacks, electrical noise and misalignment of the power consumption trace are the major factors that determine the success of the attack. Therefore, several studies have been conducted to overcome this problem, and one of them is a signal processing method based on wavelet transform. Up to now, discrete wavelet transform, which can compress the trace, has been mostly used for power side-channel power analysis because continuous wavelet transform techniques increase data size and analysis time, and there is no efficient scale selection method. In this paper, we propose an efficient scale selection method optimized for power analysis attacks. Furthermore, we show that the analysis performance can be greatly improved when using the proposed method. As a result of the CPA(Correlation Power Analysis) and DDLA(Differential Deep Learning Analysis) experiments, which are non-profiling attacks, we confirmed that the proposed method is effective for noise reduction and trace alignment.

Cataloguing of Anther Expressed Genes through Differential Slot Blot in Oriental Lily (Lilium Oriental Hybrid 'Acapulco') (아카풀코나리에서 Differential Slot Blot을 이용한 약발현 유전자 목록작성)

  • Suh, Eun-Jung;Yu, Hee Ju;Han, Bong Hee;Lim, Yong Pyo;Jeong, Mi-Jeong;Lee, Seong-Kon;Kim, Dong-Hern;Chang, An-Cheol;Yae, Byeong Woo
    • Horticultural Science & Technology
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    • v.31 no.5
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    • pp.598-606
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    • 2013
  • Anther is the major organ of flower in responsible to reproduction and outward appearance. From anther-specific cDNA library of Lilium Oriental Hybrid 'Acapulco', 2000 expressed sequence tags were selected randomly. Differential slot blot analysis with cDNA probes from the anther and leaf was used to get anther-expressed clone and 570 non-redundant ESTs were obtained and sequenced. Compared to the GenBank database using BLASTX algorithm, 191 clones showed significant similarity but others (66.5%) did not measured to known sequence. Functional categories according to gene ontology (GO) annotation included sequence representing a significant portion of protein in cell and cell part respectively. A transcriptional analysis at 7 different organs and developmental stage was performed using northern blot with thirty ESTs as putative anther specific gene. This report suggest that selection of anther expressed clone using differential slot blot was considered as very effective tool and our current study can provide fundamental information on the lily anther including pollen furthermore.

Construction of the Full-length cDNA Library and Selection of Diapause-Associated cDNA Clones from Bombyx mori Diapausing Eggs and Diapause-Activated Eggs

  • Hwnag, Jae-Sam;Go, Hyun-Jeong;Goo, Tae-Won;Yun, Eun-Young;Choi, Kwang-Ho;Seong, Su-Il;Kim, Sung-Kuk;Lee, Sang-Mong;Kim, Iksoo;Kim, Nam-Soon;Kang, Seok-Woo
    • International Journal of Industrial Entomology and Biomaterials
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    • v.9 no.1
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    • pp.145-148
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    • 2004
  • As an initial step to define the molecular mechanism of diapause during embryogenesis of the silkworm, Bombyx mori, mRNA transcripts from diapausing eggs and diapause-activated eggs were compared by differential expression using cDNA microarray. Twenty-four individual cDNA clones were identified. Amomg them, ten genes including alcohol dehydrogenase, dead box-l, cytochrome oxidase subunit I and 18 wheeler showed increased expression in the diapause-activated eggs. The rest of fourteen genes showed increased expression in diapausing eggs.

A Scientific Approach for Improving Sensitivity and Selectivity of Miniature, Solid-state, Potentiometric Carbon Monoxide Gas Sensors by Differential Electrode Equilibria Mechanism (전극평형전위차 가스 센싱 메커니즘을 적용한 일산화탄소 소형 전위차센서의 특성 향상에 관한 연구)

  • Park, Jun-Young;Kim, Ji-Hyun;Park, Ka-Young;Wachsman, Eric D.
    • Journal of the Korean Ceramic Society
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    • v.47 no.1
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    • pp.92-96
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    • 2010
  • Based on the differential electrode equilibria approach, potentiometric YSZ sensors with semiconducting oxide electrodes for CO detection are developed. To improve the selectivity, sensitivity and response-time of the sensor, our strategy includes (a) selection of an oxide with a semiconducting response to CO, (b) addition of other semiconducting materials, (c) addition of a catalyst (Pd), (d) utilization of combined p- and n-type electrodes in one sensor configuration, and (e) optimization of operating temperatures. Excellent sensing performance is obtained by a novel device structure incorporating $La_2CuO_4$ electrodes on one side and $TiO_2$-based electrodes on opposite substrate faces with Pt contacts. The resulting response produces additive effects for the individual $La_2CuO_4$ and $TiO_2$-based electrodes voltages, thereby realizing an even higher CO sensitivity. The device also is highly selective to CO versus NO with minor sensitivity for NO concentration, compared to a notably large CO sensitivity.

Adaptive Residual DPCM using Weighted Linear Combination of Adjacent Residues in Screen Content Video Coding (스크린 콘텐츠 비디오의 압축을 위한 인접 화소의 가중 합을 이용한 적응적 Residual DPCM 기법)

  • Kang, Je-Won
    • Journal of Broadcast Engineering
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    • v.20 no.5
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    • pp.782-785
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    • 2015
  • In this paper, we propose a novel residual differential pulse-code modulation (RDPCM) coding technique to improve coding efficiency of screen content videos. The proposed method uses a weighted combination of adjacent residues to provide an accurate estimate in RDPCM. The weights are trained in previously coded samples by using an L1 optimization problem with the least absolute shrinkage and selection operation (LASSO). The proposed method achieves BD-rate saving about 3.1% in all-intra coding.

Error Control Policy for Initial Value Problems with Discontinuities and Delays

  • Khader, Abdul Hadi Alim A.
    • Kyungpook Mathematical Journal
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    • v.48 no.4
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    • pp.665-684
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    • 2008
  • Runge-Kutta-Nystr$\"{o}$m (RKN) methods provide a popular way to solve the initial value problem (IVP) for a system of ordinary differential equations (ODEs). Users of software are typically asked to specify a tolerance ${\delta}$, that indicates in somewhat vague sense, the level of accuracy required. It is clearly important to understand the precise effect of changing ${\delta}$, and to derive the strongest possible results about the behaviour of the global error that will not have regular behaviour unless an appropriate stepsize selection formula and standard error control policy are used. Faced with this situation sufficient conditions on an algorithm that guarantee such behaviour for the global error to be asympotatically linear in ${\delta}$ as ${\delta}{\rightarrow}0$, that were first derived by Stetter. Here we extend the analysis to cover a certain class of ODEs with low-order derivative discontinuities, and the class of ODEs with constant delays. We show that standard error control techniques will be successful if discontinuities are handled correctly and delay terms are calculated with sufficient accurate interpolants. It is perhaps surprising that several delay ODE algorithms that have been proposed do not use sufficiently accurate interpolants to guarantee asymptotic proportionality. Our theoretical results are illustrated numerically.