• Journal of the Institute of Electronics Engineers of Korea SP
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• v.46 no.4
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• pp.157-164
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• 2009

An efficient pipeline MDC Radix-4 FFT structure is proposed in this paper. Every stages in pipeline FFT structure consists of delay' commutator and butterfly. Proposed butterflies in front and rear stages utilize CORDIC and Common Sub-expression Sharing(CSS) techniques, respectively. It is shown that proposed butterfly structure can reduce the number of adders through sharing common patterns of CSD type coefficients. The Verilog-HDL modeling and Synopsys logic synthesis results that the proposed structure show 48.2% cell area reduction in the complex multiplication part and 22.1% cell area reduction in overall 256-point FFT structure comparison with those of the conventional structures. Consequently, the proposed FFT structure can be efficiently used in various OFDM systems.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.1C
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• pp.119-128
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• 2004

In this paper, a low-power 8-point DCT structure is proposed using add and shift operations. Proposed structure adopts 4 cycles for complete 8-point DCT in order to minimize size of hardware and to enable high-speed processing. In the structure, hardware for the first cycle can be shared in the next 3 cycles since all columns in the DCT coefficient matrix are common except sign. Conventional DCT structures implemented with only add and shift operation use CSD(Canonic Signed Digit) form coefficients to reduce the number of adders. To reduce the number of adders further, we propose a new structure using common sub-expression sharing techniques. With this techniques, the proposed 8-point DCT structure achieves 19.5% adder reduction comparison to the conventional structure using only CSD coefficient form.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.4
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• pp.1867-1875
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• 2011

In this paper, a low-area 256-point FFT structure is proposed. For low-area implementation CSD(Canonic Signed Digit) multiplier method is chosen. Because multiplication type should be less for efficient CSD multiplier application to the FFT structure, the Radix-$4^2$ algorithm is chosen for those purposes. After, in the proposed structure, the number of multiplication type is minimized in each multiplication block, the CSD multipliers are applied for implementation of multiplication. Furthermore, in CSD multiplier implementation, cell-area is more reduced through common sub-expression sharing(CSS). The Verilog-HDL coding result shows 29.9% cell area reduction in the complex multiplication part and 12.54% cell area reduction in overall 256-point FFT structure comparison with those of the conventional structure.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.4A
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• pp.324-329
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• 2002

In the high-speed/low-power digital filter applications like wireless communication systems, canonical signed digit(CSD) linear phase finite impulse response(FIR) filter structures are widely investigated. In this paper, we propose a high-speed/low-power CSD linear phase FIR filter structure using vertical common sub-expression. In the conventional linear phase CSD filter, horizontal common sub-expressions are utilized due to the inherent horizontal common sub-expression of symmetrical filter coefficients. We use the fact that their MSBs are also equal since adjacent filter coefficients have similar values in the linear phase filter Through the examples, it is shown that our proposed structure is more efficient in case that precision of implementation is lower, and tap length are longer.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.10C
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• pp.1451-1459
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• 2004

In this paper, a low-power 32-point IMDCT structure is proposed for MP3. Through re-odering of IMDCT matrices, we propose the systolic structure operating with 16, 8, 4, 2, and 1 cycle, respectively. To reduce power consumption, multiplication of each sub blocks are implemented by add and shift operation with CSD(Canrmic sigled digit) form coefficients. To reduce, furthermore, the number of adders, we utilize the common sub-expression sharing techniques. With these techniques, the relative power consumption of the proposed structure is reduced by 58.4% comparison to the conventional structure using only 2's complement form coefficient. Validity of the proposed structure is proved through Verilog-HDL coding.

• Genomics & Informatics
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• v.19 no.1
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• pp.10.1-10.7
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• 2021

Although many models have been proposed to accurately predict the response of drugs in cell lines recent years, understanding the genome related to drug response is also the key for completing oncology precision medicine. In this paper, based on the cancer cell line gene expression and the drug response data, we established a reliable and accurate drug response prediction model and found predictor genes for some drugs of interest. To this end, we first performed pre-selection of genes based on the Pearson correlation coefficient and then used ElasticNet regression model for drug response prediction and fine gene selection. To find more reliable set of predictor genes, we performed regression twice for each drug, one with IC₅₀ and the other with area under the curve (AUC) (or activity area). For the 12 drugs we tested, the predictive performance in terms of Pearson correlation coefficient exceeded 0.6 and the highest one was 17-AAG for which Pearson correlation coefficient was 0.811 for IC₅₀ and 0.81 for AUC. We identify common predictor genes for IC₅₀ and AUC, with which the performance was similar to those with genes separately found for IC₅₀ and AUC, but with much smaller number of predictor genes. By using only common predictor genes, the highest performance was AZD6244 (0.8016 for IC₅₀, 0.7945 for AUC) with 321 predictor genes.

• Journal of the Korea Society of Computer and Information
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• v.21 no.5
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• pp.57-64
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• 2016

In this paper, we propose the design of railway safety common data model to provide common transformation method for collecting data from railway facility fields to Real-time railway safety monitoring and control system. This common data model is divided into five abstract sub-models according to the characteristics of data such as 'StateInfoMessage', 'ControlMessage', 'RequestMessage', 'ResponseMessage' and 'ExtendedXXXMessage'. This kind of model structure allows diverse heterogeneous data acquisitions and its common conversion method to DDS (Data Distribution Service) format to share data to the sub-systems of Real-time railway safety monitoring and control system. This paper contains the design of common data model and its DDS Topic expression for DDS communication, and presents two kinds of data transformation case studied for verification of the model design.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.41 no.5
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• pp.283-290
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• 2004

In this paper, a low-power structure for 512 tap FIR filter in MPEG audio algorithm is proposed. By using CSD(Canonic Signed Digit) form filter coefficients and maximum sharing of input signal sample, it is shown that the number of adders of proposed structure can be minimized. To minimize the number of adders, the proposed structure utilizes the 4 steps of sharing, i.e., common input sharing, linear phase symmetric filter coefficient sharing, block sharing for common input, and common sub-expression sharing. Through Verilog-HDL coding, it is shown that reduction rates in the implementation area and relative power consumption of the proposed structure are 60.3% and 93.9% respectively, comparison to those of the conventional multiplier structure.

• International Journal of Oral Biology
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• v.47 no.2
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• pp.17-24
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• 2022

Preserving intact genetic material and delivering it to the next generation are the most significant tasks of living organisms. The integrity of DNA sequences is under constant threat from endogenous and exogenous factors. The accumulation of damaged or incompletely-repaired DNA can cause serious problems in cells, including cell death or cancer development. Various DNA damage detection systems and repair mechanisms have evolved at the cellular level. Although the mechanisms of these responses have been extensively studied, the global RNA expression profiles associated with genomic instability are not well-known. To detect global gene expression changes under different DNA damage and hypoxic conditions, we performed RNA-seq after treating human cervical cancer cells with ionizing radiation (IR), hydroxyurea, mitomycin C (MMC), or 1% O₂ (hypoxia). Results showed that the expression of 184-1037 genes was altered by each stimulus. We found that the expression of 51 genes changed under IR, MMC, and hypoxia. These findings revealed damage-specific genes that varied differently according to each stimulus and common genes that are universally altered in genetic instability.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.53 no.2
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• pp.111-117
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• 2004

The low-power design of the A/D converter is indispensable to achieve the compact bio-signal measuring device with long battery duration. In this paper, new decimation filter structure is proposed for the low-power design of the Sigma-Delta A/D converter in the bio-instruments. The proposed filter is based on the non-recursive structure of the CIC (Cascaded Integrator Comb) decimation filter in the Sigma-Delta A/D converter. By combining the CSD (Canonic Signed Digit) structure with common sub-expression sharing technique, the proposed decimation filter structure can significantly reduce the number of adders for implementation. For the fixed decimation factor of 16, the 15％ of power consumption saving is achieved in the proposed structure in comparison with that of the conventional polyphase CIC filter.