• Structural Engineering and Mechanics
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• v.31 no.5
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• pp.545-566
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• 2009

Bridge columns are subjected to combined actions of axial force, shear force and bending moment during earthquakes, caused by spatially-complex earthquake motions, features of structural configurations and the interaction between input and response characteristics. Combined actions can have significant effects on the force and deformation capacity of RC columns, resulting in unexpected large deformations and extensive damage that in turn influences the performance of bridges as vital components of transportation systems. This paper evaluates the seismic response of three prototype reinforced concrete bridges using comprehensive numerical models that are capable of simulating the complex soil-structural interaction effects and nonlinear behavior of columns. An analytical approach that can capture the shear-flexural interacting behavior is developed to model the realistic nonlinear behavior of RC columns, including the pinching behavior, strength deterioration and stiffness softening due to combined actions of shear force, axial force and bending moment. Seismic response analyses were conducted on the prototype bridges under suites of ground motions. Response quantities of bridges (e.g., drift, acceleration, section force and section moment etc.) are compared and evaluated to identify the effects of vertical motion, structural characteristics and the shear-flexural interaction on seismic demand of bridges.

• Korean Journal of Pharmacognosy
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• v.22 no.3
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• pp.197-206
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• 1991

The water extract of Gamisamryungbaekchool-San increased the lifespan of mice implanted intraperitoneally with sarcoma 180. Significant depression of lethal toxicity of cis-platin $(45{\mu}M/kg,\;s.c)$ and renal toxicity (indicated by an increase in blood urea nitrogen value and creatinine value) of cis-platin $(35{\mu}M/kg,\;s.c)$ were observed in mice and rats treated with Gamisamryungbaekchool-San. RBC and WBC were significantly decreased in rats treated with cis-platin, and significant depression of hematologic toxicities of cis-platin $(35{\mu}M/kg,\;s.c)$ in rats treated with Gamisamryungbaekchool-San. After all, alleviative effect of the side actions of cis-platin was acknowledged by combined usage of Gamisamryungbaekchool-San and cis-platin.

• Korean Journal of Pharmacognosy
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• v.15 no.3
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• pp.115-120
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• 1984

'Bojungikgi-tang' consists of Astragali Radix, Ginseng Radix, Atractylodis Rhizoma alba, Glycyrrhizae Radix, Angelicae gigantis Radix, Aurantii nobilis Pericarpium, Cimicifugae Rhizoma and Bupleuri Radix. It has been widely prescribed in oriental medicine for controlling digestive functions and for health. Experimental studies were implemented on analgesic, sedative and antipyretic actions. The results showed significant analgesic and antipyretic actions were recognized. Sedative actions were significantly noted.

• Korean Journal of Pharmacognosy
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• v.16 no.1
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• pp.26-30
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• 1985

These studies were conducted to investigate the effect of Yijin-tang on the anticonvulsion, analgesic, sedative actions, effect on blood vessels and blood pressure. The result of these studies was summarized as follows; Suppressive action was shown on convulsion due to cerebrocortical causes, but no such actions were noted either myelic or diencephaltic causes in mice. Analgesic and sedative actions were significantly recognized in mice. Increasing of blood pressure and vasocontractive actions were noted.

• Korean Journal of Pharmacognosy
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• v.13 no.3
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• pp.122-128
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• 1982

In order to investigate the pharmacological action of combined preparation of crude drugs, 'Oyo-Tang' were studied. 'Oyo-Tang' consist of Glycyrrhizae Radix, Ephedrae Herba, Armenicae Semen, Platycodi Radix and Nepetae Herba. They have widely been prescribed in Oriental Medicine for controlling of cough, asthma, nasal abstraction, pharygeal pain and hoarseness. Experimental studies were implemented on analgesic, sedativc, anticonvulsive and ileum relaxing actions. The results of the studies were as follows; Significant anticonvulsive action was recognized by fraction IIII. Sedative and analgesic actions were noted by fraction I and III. Relaxing action was shown on the extracted ileum in mice, antagonistic actions were seen on $BaCl_2-induced$ contraction of the ileum of mice and Histamine-induced contraction of the ileum of guinea-pigs that the relaxing effect of the intestinal smooth muscle was recognized.

• Korean Journal of Pharmacognosy
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• v.13 no.2
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• pp.79-86
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• 1982

In order to investigate pharmacological actions of combined preparations of crude drugs, 'Jakyakgamcho-Tang' were studied. The 'Jakyakgamcho-Tang' using abdominal pain and convulsion of pediatric diseases are composed of Glycyrrhizae Radix and Paeoniae Radix alba. This study was undertaken to investigate the effect of 'Jakyakgamcho-Tang'(S-I) and parched 'Jakyakgamcho-Tang'(S-II) on anticonvulsive, analgesic, antipyretic and sedative actions. The results of this study were summarized as follows; Both 'Jakyakgamcho-Tang' and parched 'Jakyakgamcho-Tang' showed anticonvulsive effects against convulsions induced by strychnine, picrotoxine and caffeine. 'Jakyakgamcho-Tang' and parched 'Jakyakgamcho-Tang' also showed analgesic and antipyretic effects. Parched 'Jakyakgamcho-Tang' only prolonged the duration of hypnosis induced by sodium pentobarbital.

• Structural Engineering and Mechanics
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• v.17 no.6
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• pp.829-862
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• 2004

This paper presents a method for the nonlinear analysis of beam elements subjected to the cyclical combined actions of torsion, biaxial flexure and axial forces based on an extension of the disturbed compression field (DSFM). The theoretical model is based on a hybrid formulation between the full rotation of the cracks model and the fixed direction of the cracking model. The described formulation, which treats cracked concrete as an orthotropic material, includes a new approach for the evaluation of the re-orientation of both the compression field and the deformation field by removing the restriction of their coincidence. A new equation of congruence permits evaluating the deformation of the middle line. The problem consists in the solution of coupled nonlinear simultaneous equations expressing equilibrium, congruence and the constitutive laws. The proposed method makes it possible to determine the deformations of the beam element according to the external stresses applied.

• Steel and Composite Structures
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• v.19 no.3
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• pp.615-633
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• 2015

Composite steel-concrete beams are used frequently in situations where axial forces are introduced. Some examples include the use in cable-stayed bridges or inclined members in stadia and bridge approach spans. In these situations, the beam may be subjected to any combination of flexure and axial load. However, modern steel and composite construction codes currently do not address the effects of these combined actions. This study presents an analysis of composite beams subjected to combined loadings. An analytical model is developed based on a cross-sectional analysis method using a strategy of successive iterations. Results derived from the model show an excellent agreement with existing experimental results. A parametric study is conducted to investigate the effect of axial load on the flexural strength of composite beams. The parametric study is then extended to a number of section sizes and employs various degrees of shear connection. Design models are proposed for estimating the flexural strength of an axially loaded member with full and partial shear connection.

• Steel and Composite Structures
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• v.43 no.4
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• pp.483-500
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• 2022

Cold-formed steel wall panels sheathed with gypsum plasterboard have shown superior thermal and structural performance in fire. Recent damage caused by fire events in Australia has increased the need for accurate fire resistance ratings of wall systems used in low- and mid-rise construction. Past fire research has mostly focused on light gauge steel framed (LSF) walls under uniform axial compression and LSF floors under pure bending. However, in reality, LSF wall studs may be subject to both compression and bending actions due to eccentric loading at the wall to-roof or wall-to-floor connections. In order to investigate the fire resistance of LSF walls under the effects of these loading eccentricities, four full-scale standard fire tests were conducted on 3 m × 3 m LSF wall specimens lined with two 16 mm gypsum plasterboards under different combinations of axial compression and lateral load ratios. The findings show that the loading eccentricity can adversely affect the fire resistance level of the LSF wall depending on the magnitude of the eccentricity, the resultant compressive stresses in the hot and cold flanges of the wall studs caused by combined loading and the temperatures of the hot and cold flanges of the studs. Structural fire designers should consider the effects of loading eccentricity in the design of LSF walls to eliminate their potential failures in fire.

• Structural Engineering and Mechanics
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• v.5 no.6
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• pp.743-754
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• 1997

A three-dimensional constitutive modeling for reinforced concrete is presented for finite element nonlinear analysis of reinforced concrete. The targets of interest to the authors are columns confined by lateral steel hoops, RC thin shells subjected to combined in-plane and out-of-plane actions and massive structures of three-dimensional (3D) extent in shear. The elasto-plastic and continuum fracture law is applied to pre-cracked solid concrete. For post cracking formulation, fixed multi-directional smeared crack model is adopted for RC domains of 3D geometry subjected to monotonic and reversed cyclic actions. The authors propose a new scheme of decomposing stress strain fields into sub-planes on which 2D constitutive laws can be applied. The proposed model for 3D reinforced concrete is experimentally verified in both member and structural levels under cyclic actions.