• Title/Summary/Keyword: challenge

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Immune response and efficacy of pigeon pox virus vaccine and fowl pox virus vaccine in chickens

  • Shil, Niraj Kanti;Rahman, Md Siddique;Hossain, M.T.;Islam, M.T.;Rahman, M.M.;Islam, K.B.M. Saiful;Cha, Se-Yeoun;Jang, Hyung-Kwan;Song, Hee-Jong
    • Korean Journal of Veterinary Service
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    • v.30 no.4
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    • pp.497-503
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    • 2007
  • The humoral immune response of chicken vaccinated with fowl and pigeon pox virus vaccines was determined with the protective potentiality of the two vaccines in field condition of Bangladesh. Different aged Fayoumi chicks were subjected for the study. To assess the relationship with better immune response among experimental groups, the average percentage of 'take reaction' was examined and recorded to 97.77% in group A, 93.33% in group B and 100.0% in group C. The level of immune status induced by different vaccinated group was measured by passive hemagglutination (PHA) microplate test method. The mean PHA titer levels after primary vaccination were $33.06{\pm}14.13$ in group A, $32.0{\pm}14.81$ in group B, and $33.0{\pm}13.66$ in group C. Following booster vaccination, the mean PHA titer levels in prior of challenge were increased to $55.46{\pm}14.64$ in groups A and C, and $46.93{\pm}16.52$ in group B. The recorded PHA titer levels of each group at two weeks after challenge were significantly increased to $106.66{\pm}31.22$, $93.86{\pm}33.04$ and $110.93{\pm}29.29$, respectively. The PHA titer levels after vaccination and challenge were significantly increased compared to pre-vaccination titer levels (P<0.01). Although the PHA titer levels among three groups administrated different vaccine combinations in prior of challenge were significantly varied (P<0.01), it was observed that all of the vaccinated chicks were highly protected against challenge infection.

An Empirical Study on the Flow Experience Affected by Characteristics of Mobile Internet (모바일 인터넷 특성이 플로우 경험에 미치는 영향에 관한 연구)

  • Yoo, Sang-Jin;Choi, Eun-Bin;Kim, Hyo-Jung
    • Information Systems Review
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    • v.8 no.1
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    • pp.125-139
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    • 2006
  • Recently, as mobile internet users grow rapidly, mobile internet companies are experiencing a fierce competition to capture new customers. Under this business environment, they try to identify factors that make people use mobile internet in order to satisfy customers by providing better and diversified services. There has been enormous effort to analyze customers' behavior in choose and use mobile internet services. However, there is no one best methodology to identify factors to attract customers yet. Thus, the study applied the flow construct proposed by Csikszentmihalyi(1977) and expanded by Hoffman and Novak(1996) to identify environmental factors of internet which has impact on users' mobile internet usage. To implement the study, the following activities have been done: literature reviews on service acceptance model and flow structure, questionnaire survey, suggestion of the flow model on mobile internet, and hypothesis test. For the study, 242 out of 307 samples collected were statistically analyzed using SPSS 10.0, AMOS 4.0 statistics package. The findings of this study are as follows: First, mobile internet environment factors influencing on challenge of flow antecedent were media characteristics(use of convenience, transmission quality), contents characteristics(uniqueness, timeliness, simplicity). Second, mobile internet environment factors influencing on skill of flow antecedent were contents(uniqueness, timeliness, simplicity), charge(definiteness and diversity of charge), usage(security, instant connectivity). Third, challenge of flow antecedent had a significant effect on flow of mobile internet usage. But it was not statistically significant that skill has an influence on flow. This study discovered the relationship between mobile internet environment factors(media characteristics, contents characteristics, charge characteristics, usage characteristics) and flow experience of mobile internet users which would be a valuable insight for marketing strategies. Results shows that challenge of flow antecedent have a significant impact on flow experience in mobile internet environment. Additional, media characteristics, contents characteristics of mobile internet environment factors is positively correlated with challenge of flow antecedent. In other words, mobile internet companies should provide customers with diverse service and take a challenging attitude to get customers show aggressive attitude in mobile internet usage.

Differential Excretion of Urinary Eosinophil Protein X after Methacholine Challenge Test in Children with Asthma (천식 환아에서 요중 Eosinophil Protein X의 메타콜린 기관지 유발 시험 전·후의 변화)

  • Shin, Su-A;Oh, Jae-Won;Lee, Ha-Baik
    • Clinical and Experimental Pediatrics
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    • v.46 no.5
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    • pp.495-499
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    • 2003
  • Purpose : Eosinophil is one of the important inflammatory cell involved in the airway inflammation in childhood asthma. It has been demonstrated that markers of eosinophil activation, including eosinophil cationic protein or eosinophil protein X(EPX), are increased in childhood asthma. Furthermore, they are related to disease activity and are assumed to be helpful in monitoring the treatment effect as urinary EPX(U-EPX) can be obtained easily and in a noninvasive way in children of all ages. Methods : Twenty-five children(22 male and three female) aged $11.87{\pm}3.82$ years with stable asthma were challenged with methacholine and urine was collected from each child during the following periods; before methacholine challenge test(MCT); 0-3 hr after the end of MCT; 4-7 hr after the end of MCT; and 8-24 hr after the end of MCT. Bronchial reactivity was determined by using Dosimeter( Jeager, Germany) with serially diluted methacholine from 0.05 to 25.0 mg. The $FEV_1$ less than 80% of baseline value were classified into positive MCT. U-EPX was measured with a sensitive and specific radioimmunoassay(Pharmacia & Upjohn AB, Uppsala, Sweden). Results were expressed as ${\mu}gEPX/mmol$ creatinine. Results : An early airway response after MCT was associated with an increase of U-EPX excretion for 0-3 hr after methacholine inhalation in comparison with beseline values. Most subjects showed a small increase in U-EPX excretion during late asthmatic response for 4-7 hr, which then decreased to normal level in 8-24 hr. Also, a tendency for a higher increase of U-EPX was associated with a lower threshold of methacholine challenge and a longer duration of asthma. Conclusion : Measurement of EPX in urine is a noninvasive and easy method to assess the severity of airway inflammation in asthmatic children. It may be a helpful index of the events underlying the airway inflammatory responses during nonspecific bronchial challenge, and in monitoring asthma management.

The Perceived Symptom and Preventive Behavior Related to Asian Dust Event: in South Korean and Chinese (한국인과 중국인의 황사로 인한 자각증상 및 예방행동)

  • Chang, Moon-Hee;Ha, Eun-Hee;Suh, Young-Ju;Lee, Bo-Eun;Kwon, Ho-Jang;Hwang, Seong-Sik;Li, Zhong-Min;Seo, Ju-Hee;Kim, Byung-Mi
    • Journal of Korean Society for Atmospheric Environment
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    • v.25 no.1
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    • pp.26-37
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    • 2009
  • Recently rapid environmental changes due to desertification and industrialization in China make a threat to Korea, especially during Asian Dust Event (ADE). This study was aimed to compare symptoms and behaviors related to ADE between Korea and China. We conducted questionnaires on self-reported symptoms and behaviors before and during ADE. Korean and Chinese subjects were grouped into children, adults, and elderly by nation (n=791). Statistical analyses were performed by $X^2$-test, Fisher's exact test, t-test and chow's test for comparing differences between Korean and Chinese. We estimated the odds ratio for perceived symptoms during ADE by preventive behavior, using Generalized Estimation Equation (GEE). The study indicated that there were significant differences between symptoms in Korea and those in China such as cold, cough, and sore throat, especially in elderly. Preventive behaviors such as avoiding outdoor activity and wearing sunglasses were more often performed in China than Korea. However wearing mask was more often performed in Korea than China. After adjusting for age, sex, educational level, and smoking status, the odds ratio (OR) of dry cough symptom in Korea was significantly decreased by closing the windows and wearing a mask during ADE. In China, the OR of dry cough symptom was decreased by wearing a mask and avoiding outdoor activity. We found that China which had higher performance of preventive behavior showed lower prevalence of symptoms during ADE than Korea. Also preventive behaviors could affects prevalence of symptoms during ADE. This results suggest that preventive behavior. could reduce symptoms during ADE and there are needed for. more attentions to reduce a threat of ADE.

Effects of Cultural Challenge and Economic Hardship on Intention to Divorce among the Multicultural Couples : Interdependence and Relationship Patterns Viewed Through Actor and Partner Effects (문화적 도전과 경제적 곤란이 다문화부부의 이혼의사에 미치는 영향 : 자기효과와 상대방효과로 본 상호의존성과 관계패턴)

  • Hyun, Kyoungja;Kim, Jeonghwa
    • Korean Journal of Social Welfare
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    • v.67 no.2
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    • pp.203-236
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    • 2015
  • Given the interdependence of a marital couple, this study examined the effects of both cultural challenge and economic hardship on intention to divorce among the multicultural couple using the actor-partner interdependence model(APIM), and explored dyadic patterns of actor and partner effects. 415 couples(n=830) participated in this self-administered questionnaire study. Results of path analyses based on APIMs revealed that for Korean husbands perceived cultural challenge contributed positively to divorce intention of the couple showing both actor and partner effects, whereas for immigrant wives such perception showed only an actor effect. In contrast, perceived economic hardship among the husbands had little effect on divorce intention of both husbands and wives, whereas such perception by wives had both actor and partner effects on divorce intention. Results of dyadic pattern analyses performed by Bootstrap indicated the actor-only pattern and the couple pattern of perceived cultural challenge on divorce intention of husbands and wives respectively. In case of perceived economic hardship comparison of the effect size suggested the partner-only pattern and the actor-only pattern for divorce intention of husbands and wives respectively. These findings implied that in order to promote conjugal harmony and to prevent the multicultural family from being dissolved, Korean husbands need to develop greater cultural competence so as to tolerate cultural differences between the couple, whereas immigrant wives and their families need to develop greater economic competence so as to foster a hope for economic reliance.

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Impact of Job Rotation Stress in Nurses on Psychological Well-being: Focusing on Mediating Effect of Challenge Assessment and Hindrance Assessment (간호사의 직무순환 스트레스가 심리적 안녕감에 미치는 영향: 도전적 평가와 방해적 평가의 매개효과 중심으로)

  • Lee, Hanna;Kim, Jung Min;Han, Jeong Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.10
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    • pp.373-381
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    • 2017
  • This study was conducted to establish and verify a theoretical model that explains the factors and pathways influencing the psychological well-being of nurses. The subjects of this study were nurses working in four general hospitals with over 200 beds in B city and G province. The results of verifying the path coefficient of the nurses' job rotation stress showed that job rotation stress had a significant effect on challenge stress, hindrance stress, and nurses' psychological well-being, while hindrance stress had a negative effect on nurses' psychological well-being. Nurses' job rotation stress had direct effects on challenge stress, hindrance stress, and psychological well-being. Hindrance stress had a direct effect on psychological well-being. In addition, nurses' job rotation stress had an indirect effect on psychological well-being through hindrance stress. Nurses who experienced job rotation showed challenge and hindrance stress. Since hindrance stress interferes with the psychological well-being of nurses, it is necessary to manage stress and make efforts in the nursing organization. Therefore, nursing organizations should establish a positive organizational environment and develop systematic strategies so that job rotation can be a challenging stress factor for nurses.

Chinese Broadcasters' Perceptions on Localization of Korean Entertainment Formats in China-Focused on In-depth Interviews on and (한국 예능 포맷의 중국 현지화에 대한 중국내 방송종사자의 인식 -<대단한 도전>과 <달려라 형제>에 대한 심층인터뷰를 중심으로)

  • Wang, Ying-Ying;Choi, E-Jung
    • The Journal of the Korea Contents Association
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    • v.19 no.11
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    • pp.57-70
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    • 2019
  • Despite both the Korean version of and seemed to be the most popular in China, the and the , which localized the same format, differed at least in terms of viewership. Focusing on these two opposing cases, this study examines the characteristics and considerations of the localization transformation through in-depth interviews with experts in China.. As a result, was positive in terms of character diversification and online media interworking effects. However, the experts recognized that factors such as the confusion of character combinations due to frequent change of performers, frequent absences, conservative characteristics of Chinese state broadcasting that emphasized educational contents, and burden of localization due to changes in mission and challenge form each time were negatively affected. On the other hand, lacked the effect of online media interaction and lack of diversity of performers. However, the use of star actors' celebrities, the merits of actors with the characteristics of Chinese historical and cultural spaces, the use of Chinese flavors and fragrances, and similar types of missions and maintaining a stable composition each time favored localized production formats.

Vaccination Studies against Fowl Pox in Chickens (닭에서 계두 예방 접종에 관한 연구)

  • Shil, N.K.;Rahman, M.S.;Paul, S.;Cha, S.Y.;Jang, H.K.;Song, H.J.
    • Korean Journal of Poultry Science
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    • v.34 no.4
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    • pp.253-257
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    • 2007
  • Fayoumi chicks were vaccinated with fowl pox virus vaccine and pigeon pox virus vaccine. The protective potentiality of the two vaccines was compared in field condition in Bangladesh. The percentage of 'take reaction' was assessed to conclude its relationship with better immune response and recorded 93.33% and 100% in birds of group B and group C, respectively. The mean passive hemagglutination (PHA) antibody titre after primary vaccination was $32{\pm}14.81$ in group B and $33{\pm}13.66$ in group C. Following booster vaccination, the mean PHA titres level at pre challenge of group B was $46.93{\pm}16.52\;and\;55.46{\pm}14.64$ in group C. The PHA titre of group B and C at two weeks post challenge recorded $93.86{\pm}33.04\;and\;110.93{\pm}29.29$, respectively. PHA titre significantly (P<0.01) increased after vaccination and post challenge compared to pre- vaccination titre. There was significant variation (p<0.01) of PHA titre at pre challenge in these groups using different vaccine combinations, but all the vaccinated birds resisted challenge infection.

Evaluation for Protective Effect of CPV-2 and CPV-2b Vaccines against a Korean CPV-2a Isolate in Pups (국내에서 유행하는 CPV-2a 분리주에 대한 CPV-2와 CPV-2b 백신의 방어효능 평가)

  • Jeoung, Seok-Young;Yi, Jun-Seok;Kim, Hyun-Tae;Kim, Doo
    • Journal of Veterinary Clinics
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    • v.31 no.5
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    • pp.361-366
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    • 2014
  • The aim of this study was to determine if vaccines containing CPV-2 or CPV-2b provided protection against challenge with a recent Korean CPV-2a isolate. Twenty mongrel pups aged 9 weeks old were used. The commercial CPV-2 or CPV-2b vaccines were administered to each of the 8 pups thrice every 3 weeks, respectively. Two weeks after the last vaccination, all pups were challenged with CPV-2a (VR00174 strain) $1{\times}10^6\;TCID_{50}$. Clinical signs, fecal excretion of challenged CPV, and serological response of pups were observed for 2 weeks after challenge. All vaccinated pups did not display any clinical signs of disease after challenge with Korean CPV-2a isolate, whereas all non-vaccinated pups exhibited mucoid or hemorrhagic diarrhea, vomiting and anorexia. In all non-vaccinated pups, the virus could be detected in feces from 4 days after challenge, whereas in vaccinated pups, no evidence of viral excretion could be detected. Two of 4 non-vaccinated pups died 6 days after the challenge. This study showed that the two commercial CPV-2 and CPV-2b vaccines were effective in preventing infection and/or disease caused by the Korean CPV-2a isolate.

The Effect of Startup Support Policy on Entrepreneurship: Focusing on TIPS Support Projects by the Ministry of SMEs and Startups (창업지원정책이 기업가정신에 미치는 영향: 중소벤처기업부 팁스(TIPS) 지원사업을 중심으로)

  • Kim, Mijoo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.3
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    • pp.1-17
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    • 2022
  • This study studied the effect of the TIPS support project of the Ministry of SMEs and Startups on the entrepreneurship of TIPS start-ups. The Tips start-up company, which is the subject of the study, was selected for the TIPS support project, participated in all commercialization funds, incubation facilities, and capacity building programs, and was selected as a company that received private investment. One-on-one in-depth interviews were conducted for about eight weeks from January 14, 2022 to March 11, 2022. For this study, the TIPS support project was subdivided into four categories: commercialization funds, incubation facilities, capacity building programs, and private investment attraction, and entrepreneurship factors were classified into four categories: innovation, challenge spirit, leadership, and risk-taking. As a result of the in-depth interview, the influence of the TIPS support project on entrepreneurship factors was in the order of challenge spirit, innovation, risk-taking, and leadership. Specifically, it was found that commercialization funds influenced innovation and risk-taking, incubation facilities had a challenge spirit and risk-taking, competency-building programs had a challenge spirit and leadership, and attracting private investment had an influence on innovation and challenge spirit. The implications of this study are that the TIPS support project, a private investment-led technology start-up support program, was introduced in 2013 and as of the end of March 2022, and a report was prepared focusing on visible performance such as private investment performance and employment rate. However, through this study, by analyzing whether the TIPS support project contributed to the cultivation of entrepreneurship for TIPS start-ups, it was found that it had a positive influence not only on quantitative growth but also on qualitative growth.