• Journal of Korean Society of Environmental Engineers
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• v.37 no.12
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• pp.689-695
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• 2015

A biofilm filtration for the removal of gaseous pollutants has been recognized as a process with a complex interaction between the gas flow characteristics and the process operating variables. This study aims to develop an one dimensional dynamic numerical model which can be utilized as a tool for the analysis of biofilm filtration process operated in plug flow mode. Since, in a plug flow system, minor environmental changes in a gaseous unit process cause a drastic change in reaction and the interaction between the pollutants is an influencing factor, plug flow system was generalized in developing the model. For facilitation of the model development, dispersion was simplified based on the principles of material balance. Several reactions such as competition, escalation, and control between the pollutants were included in the model. The applicability of the developed model was evaluated by taking the calibration and verification steps on the experimental data performed for the removal of BTX at both low and high flow concentration. The model demonstrated a correlation coefficient ($R^2$) greater than 0.79 under all the experimental conditions except for the case of toluene at high flow condition, which suggested that this model could be used for the generalized gaseous biofilm plug flow filtration system. In addition, this model could be a useful tool in analyzing the design parameters and evaluating process efficiency of the experiments with substantial amount of complexity and diversity.

• Archives of design research
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• v.19 no.4 s.66
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• pp.187-204
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• 2006

The brand personality of online products and services is know as its e-brand personality. Although, in the competitive conditions of online markets, e-brand personality is agreed to be an important factor, few studies have suggested how to establish e-brand personality through the visual design of web sites. This study identifies and verifies causal relationships between the visual attributes of web pages and e-brand personalities. The first identifies four major dimensions of e-brand personality on diverse web sites. The second uses 52 experimental home pages to identify key visual attributes associated with those four personality dimensions. The third is a confirmatory study with 16 experimental web sites that verifies causal relationships between visual attributes and e-brand personalities. The results show that two visual attributes, 'simplicity' and 'cohesion,' help to establish a 'bold' personality. Three attributes, 'contrast,' 'density,' and 'regularity,' affect whether a site has an 'analytical' personality. 'Contrast,' 'cohesion,' 'density,' and 'regularity' all influence whether a web site is perceived to have a 'friendly' personality. 'Regularity' and 'balance' were expected to affect the 'sophisticated' personality dimension, but no such impact was observed. The paper concludes with a discussion of implications, limitations, and future research directions.

• Journal of Preventive Medicine and Public Health
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• v.28 no.1 s.49
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• pp.153-174
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• 1995

This study was conducted to examine the determinant factors for expenditure of the medical insurance program for self-employeds based on the analysis of 1991 'The Medical Insurance Program for Self-Employeds Statistical Yearbook', and also similar yearbooks in the metropolitan and other provinces. The major findings are as follows : We have divided benefits into these four components such as the utilization rate for out-patients, expenses per claim for out-patients as paid by the insurer, utilization rate for in-patients, and the expenses per claim for in-patients as paid by the insurer, in order to examine the determinant factors for it. The results of the study revealed the following findings, in urban areas, the supply of medical care had more influence on the benefits than other demographic and economic variables, while, in county areas, both the supply of medical care and the rate of those aged over 65 affected the provision of benefits. The determinant factors for financial balance of the medical insurance program for self-employeds are, first, the determinant factor for administrative expenses was the number of households. The more the number of households, the less the administrative expenses per the insured. This shows that the economy of scale is being. And so, the administrative district must be taken into consideration in the incorporation of small regional medical societies and should be re-organized for more efficient management. Second, in urban areas, the supply of medical care had more influence on utilization rate and expenses per claim as paid by insurer, and therefore it is necessary to control it. In county areas, the supply of medical care and the rate of those aged over 65 raised the utilization rate and expenses per claim as paid by insurer. For the financial stability of county areas, a common fund for medical care for the aged and expansion of finance stabilization fund would be necessary. But, in county areas, it would be unnecessary to control the supply of medical care because it was much more insufficient than in urban areas. The vitalization of public health facilities must be carried out in county areas, for they reduced benefits. Sice the more insured in a single household, the less the utilization of the medical insurance program, benefits for habilitation at home should be given consideration. The law of majority and the economy of scale were applied here, and therefore the incorporation of regional medical societies must be taken into consideration. In integrating regional medical societies, it would be absolutely necessary to review the structural differences among all regional medical societies, the medical demand of each region, and also the local characteristics of each region.

• Journal of Korean Society of Transportation
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• v.35 no.5
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• pp.396-408
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• 2017

In Korea, the number of elderly has been increasing rapidly. So it is also expected that the economic activity and the trip frequency of the elderly will increase. On the other hand, elderly related accidents such as falls during walking are steadily increasing and the satisfaction about pedestrian environment of elderly is very low. In this paper, we found one of the reasons for these dissatisfaction in pedestrian facility, which is not considering the walking ability (about 75% of non-elderly person) of the elderly. So, we analyze the kinematic walking characteristics of the elderly with the motion analysis system, when the elderly use stairs. As a result of analysis of various walking variables, the current standard for stairway height in Korean law (18cm) requires excessive force to elderly so it was difficult for elderly to keep the balance of the body in ascending and descending walk of stairs. In this paper, we propose the stair design criteria through the cluster analysis of walking parameters reflecting the gait characteristics of the elderly. This change is not a big for non-elderly person, but it can promote more socioeconomic activities for the elderly.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2002.07a
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• pp.113-113
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• 2002

Phylogenetically conserved Bcl-2 family proteins play a pivotal role in the regulation of apoptosis from virus to human. Members of the Bcl-2 family consist of antiapoptotic proteins such as Bcl-2, Bcl-xL, and Bcl-w, and proapoptotic proteins such as BAD, Bax, BOD, and Bok. It has been proposed that anti- and proapoptotic Bcl-2 proteins regulate cell death by binding to each other and forming heterodimers. A delicate balance between anti- and proapoptotic Bcl-2 family members exists in each cell and the relative concentration of these two groups of proteins determines whether the cell survives or undergoes apoptosis. Mcl-1 (Myeloid cell :leukemia-1) is a member of the Bcl-2 family proteins and was originally cloned as a differentiation-induced early gene that was activated in the human myeloblastic leukemia cell line, ML-1 . Mcl-1 is expressed in a wide variety of tissues and cells including neoplastic ones. We recently identified a short splicing variant of Mcl-1 short (Mcl-IS) and designated the known Mcl-1 as Mcl-1 long (Mcl-lL). Mcl-lL protein exhibits antiapoptotic activity and possesses the BH (Bcl-2 homology) 1, BH2, BH3, and transmembrane (TM) domains found in related Bcl-2 proteins. In contrast, Mcl-1 S is a BH3 domain-only proapoptotic protein that heterodimerizes with Mcl-lL. Although both Mc1-lL and Mcl-lS proteins contain BH domains fecund in other Bcl-2 family proteins, they are distinguished by their unusually long N-terminal sequences containing PEST (proline, glutamic acid, serine, and threonine) motifs, four pairs of arginine residues, and alanine- and glycine-rich regions. In addition, the expression pattern of Mcl-1 protein is different from that of Bcl-2 suggesting a unique role (or Mcl-1 in apoptosis regulation. Tankyrasel (TRF1-interacting, ankyrin-related ADP-related polymerasel) was originally isolated based on its binding to TRF 1 (telomeric repeat binding factor-1) and contains the sterile alpha motif (SAM) module, 24 ankyrin (ANK) repeats, and the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP). Previous studies showed that tankyrasel promotes telomere elongation in human cells presumably by inhibiting TRFI though its poly(ADP-ribosyl)action by tankyrasel . In addition, tankyrasel poly(ADP-ribosyl)ates Insulin-responsive amino peptidase (IRAP), a resident protein of GLUT4 vesicles, and insulin stimulates the PARP activity of tankyrase1 through its phosphorylation by mitogen-activated protein kinase (MAPK). ADP-ribosylation is a posttranslational modification that usually results in a loss of protein activity presumably by enhancing protein turnover. However, little information is available regarding the physiological function(s) of tankyrase1 other than as a PARP enzyme. In the present study, we found tankyrasel as a specific-binding protein of Mcl-1 Overexpression of tankyrasel led to the inhibition of both the apoptotic activity of Mel-lS and the survival action of Mcl-lL in mammalian cells. Unlike other known tankyrasel-interacting proteins, tankyrasel did not poly(ADP-ribosyl)ate either of the Mcl-1 proteins despite its ability to decrease Mcl-1 proteins expression following coexpression. Therefore, this study provides a novel mechanism to regulate Mcl-1-modulated apoptosis in which tankyrasel downregulates the expression of Mcl-1 proteins without the involvement of its ADP-ribosylation activity.

• Journal of Elementary Mathematics Education in Korea
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• v.19 no.4
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• pp.457-484
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• 2015

This study aims to investigate an approach to teach proportional reasoning in elementary mathematics class by analyzing the proportional strategies the students use to solve the proportional reasoning tasks and their percentages of correct answers. For this research 174 sixth graders are examined. The instrument test consists of various questions types in reference to the previous study; the proportional reasoning tasks are divided into algebraic-geometric, quantitative-qualitative and missing value-comparisons tasks. Comparing the percentages of correct answers according to the task types, the algebraic tasks are higher than the geometric tasks, quantitative tasks are higher than the qualitative tasks, and missing value tasks are higher than the comparisons tasks. As to the strategies that students employed, the percentage of using the informal strategy such as factor strategy and unit rate strategy is relatively higher than that of using the formal strategy, even after learning the cross product strategy. As an insightful approach for teaching proportional reasoning, based on the study results, it is suggested to teach the informal strategy explicitly instead of the informal strategy, reinforce the qualitative reasoning while combining the qualitative with the quantitative reasoning, and balance the various task types in the mathematics classroom.

• Korea journal of population studies
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• v.34 no.1
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• pp.1-25
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• 2011

There are two main purposes in this study. First, we compare the effects of wives' characteristics with the effects of the husbands' characteristics on the induced abortion. Second, we analyze whether the determinants of the induced abortion have changed according to parity and conception period. The main findings are follows. First, both wives' and husbands' socioeconomic characters have insignificant effects on the induced abortion at parity 0, in the 1997 and 2000 Korean Fertility Survey data. Second, during the periods of the lowest-low fertility, after 2000 in Korea, wives' employments have positive effects at parity 0 and 1, while husbands' educational levels have negative effects at parity 1 on the induced abortion. The implications are as follows. First, having children had been the universal social phenomenon before 2000 in Korea. however, after 2000, reproductions have become the women's choice, lather than the duty of married women. Women must weight the balance between the benefits and the costs of children so that women's fertility behaviors become a rational choice. Women's employment is the most important factor in these rational calculations. Second, both Western individualism and the traditional Korean familism have significant effects on the fertility behavior and the induced abortions in Korea. This rejects the diffusion theory, which tells that the traditional familism must be replaced by the Western individualism in order to decline the fertility rates in developing countries.

• Informatization Policy
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• v.27 no.3
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• pp.82-111
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• 2020

Recently, increasing use of big data have caused regulation factors of personal information and combination of pseudonymized information to emerge as key policy measures. Therefore, this study empirically analyzed the mediating effect and moderating effect of pseudonymized information combination as the third variable in the relationship between regulation factors of personal information and big data utilization. The analysis showed the following results: First, among personal information regulation factors, definition regulation, consent regulation, supervisory authority regulation, and punishment intensity regulation showed a positive(+) relationship with the big data utilization, while among pseudonymized information combination factors, non-identification of combination, standardization of combined pseudonymized information, and responsibility of combination were also found to be in a positive relationship with the use of big data. Second, among the factors of pseudonymized information combination, non-identification of combination, standardization of combined pseudonymized information, and responsibility of combination showed a positive(+) mediating effect in relation to regulation factors of personal information and big data utilization. Third, in the relationship between personal information regulation factors and big data utilization, the moderating effect hypothesis that each combination institution type of pseudonymized information (free-type, intermediary-type, and designated-type) would play a different role as a moderator was rejected. Based on the results of the empirical research, policy alternatives of 'Good Regulation' were proposed, which would maintain balance between protection of personal information and big data utilization.

• Korean Journal of Environment and Ecology
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• v.29 no.6
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• pp.873-883
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• 2015

From August 2012 to April 2013, the ichthyofauna and post-restoration properties of Yangjae stream were investigated. A total of 1,503 fish of 2 forms, 16 species and 5 families were studied during the survey period. A survey of the distribution of freshwater fish inhabiting Yangjae stream after restoration of the stream showed large populations of Zacco platypus and Rhynchocypris oxycephalus. From the frequency distribution of the total length for the Zacco platypus population inhabiting Yangjae stream, it was estimated that there are 4 distinct age groups, with an abundance of the 27-63 mm (Age $0^+$) category accounting for 51.3% of the population. The regression coefficient (b) for the length-weight relationship in Zacco platypus was 3.27, while the slope of the condition factor was positive, demonstrating that stable growth conditions are being maintained. Analysis of tolerance and trophic guilds showed a decrease in the numbers of sensitive species and insectivore species further downstream, and an increase in tolerant species and omnivore species. Principal component analysis using community indices and indices of biotic integrity (IBI) showed that there were differences according to the survey time: the first and second surveys showed major changes on certain single species populations while during the third survey, it was analyzed that the populations of various types of fish had established balance.

• Ocean Systems Engineering
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• v.6 no.1
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• pp.61-97
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• 2016

This is the second of two papers on the 3D numerical modeling of nearshore hydro- and morphodynamics. In Part I, the focus was on surf and swash zone hydrodynamics in the cross-shore and longshore directions. Here, we consider nearshore processes with an emphasis on the effects of oceanic forcing and beach characteristics on sediment transport in the cross- and longshore directions, as well as on foreshore bathymetry changes. The Delft3D and XBeach models were used with four turbulence closures (viz., ${\kappa}-{\varepsilon}$, ${\kappa}-L$, ATM and H-LES) to solve the 3D Navier-Stokes equations for incompressible flow as well as the beach morphology. The sediment transport module simulates both bed load and suspended load transport of non-cohesive sediments. Twenty sets of numerical experiments combining nine control parameters under a range of bed characteristics and incident wave and tidal conditions were simulated. For each case, the general morphological response in shore-normal and shore-parallel directions was presented. Numerical results showed that the ${\kappa}-{\varepsilon}$ and H-LES closure models yield similar results that are in better agreement with existing morphodynamic observations than the results of the other turbulence models. The simulations showed that wave forcing drives a sediment circulation pattern that results in bar and berm formation. However, together with wave forcing, tides modulate the predicted nearshore sediment dynamics. The combination of tides and wave action has a notable effect on longshore suspended sediment transport fluxes, relative to wave action alone. The model's ability to predict sediment transport under propagation of obliquely incident wave conditions underscores its potential for understanding the evolution of beach morphology at field scale. For example, the results of the model confirmed that the wave characteristics have a considerable effect on the cumulative erosion/deposition, cross-shore distribution of longshore sediment transport and transport rate across and along the beach face. In addition, for the same type of oceanic forcing, the beach morphology exhibits different erosive characteristics depending on grain size (e.g., foreshore profile evolution is erosive or accretive on fine or coarse sand beaches, respectively). Decreasing wave height increases the proportion of onshore to offshore fluxes, almost reaching a neutral net balance. The sediment movement increases with wave height, which is the dominant factor controlling the beach face shape.