• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.55-60
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• 2010

Caesalpinia sappan L. (C. sappan) has long been used in traditional medicine as an emmenagogue, hemostatic and anti-inflammatory agent. The present study investigated the effects of water extract of C. sappan in human lymphoma U937 cells. The proliferation of U937 cells was decreased by C. sappan in a dose-dependently manner. Anti-proliferative effect of C. sappan on U937 cells was associated with G2/M phase arrest, which was mediated by regulating the expression of p21 protein. Moreover, phosphorylation of JNK and p38 was increased by C. sappan. Blockade of JNK and p38 was significantly inhibited C. sappan-induced G2/M phase arrest. Taken together, these results suggest that Anti-proliferative effect of C. sappan on U937 is assocated with G2/M phase cell cycle arrest by expression of p21 protein and, JNK and p38 activation.

• Journal of the Institute of Electronics and Information Engineers
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• v.54 no.7
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• pp.115-124
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• 2017

The objective of study was to investigate the optimal echo phase for mouse brain enhancement scan using fast low angle shot (FLASH) sequence of 9.4T magnetic resonance imaging (MRI). For quantification based on this method, an MR phantom experiment and clinical research were done. The phantom experiment was conducted by fabricating three phantoms with different molar concentration of gadolinium to create changes in echo phase of 9.4T FLASH sequence used in mouse brain scans. In the phantom experiment, SSI was 25~27 [arbitrary units, a.u.] in each of 33 phases from $6{\pi}$ to $28{\pi}$, while RSP was 30~100 mmol. MPSI was 47~52 [a.u], while MPP, where MPSI is seen, was 0.8~9 mmol. EPMS was 80.8~108.0%, while ASIMP was formed between 21.1 and 31.8 [a.u]. In the clinical research, Finally, the occurrence rate of artifact that expressed -1 nd +1. The present study was able to quantify the degree of enhancement at FLASH sequence of 9.4T MRI, as well as identify the optimal echo phase during mouse brain enhancement scan.

• Journal of Soil and Groundwater Environment
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• v.16 no.6
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• pp.58-65
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• 2011

The bacterial uranium(VI) reduction and its resultant low solubility make this process an attractive option for removing U from groundwater. An impact of aqueous suspending iron phase, which is redox sensitive and ubiquitous in subsurface groundwater, on the U(VI) bioreduction by Shewanella putrefaciens CN32 was investigated. In our batch experiment, the U(VI) concentration ($5{\times}10^5M$) gradually decreased to a non-detectable level during the microbial respiration. However, when Fe(III) phase was suspended in solution, bioreduction of U(VI) was significantly suppressed due to a preferred reduction of Fe(III) instead of U(VI). This shows that the suspending amorphous Fe(III) phase can be a strong inhibitor to the U(VI) bioreduction. On the contrary, when iron was present as a soluble Fe(II) in the solution, the U(VI) removal was largely enhanced. The microbially-catalyzed U(VI) reduction resulted in an accumulation of solid-type U particles in and around the cells. Electron elemental investigations for the precipitates show that some background cations such as Ca and P were favorably coprecipitated with U. This implies that aqueous U tends to be stabilized by complexing with Ca or P ions, which easily diffuse and coprecipitate with U in and around the microbial cell.

• Phonetics and Speech Sciences
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• v.6 no.3
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• pp.41-48
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• 2014

This study investigated the differences between emotional parameters BDI, VHI, STAI-X-I and STAI-X-II according to the menstrual cycles of the female and the relation between changes of the depression index and voice characteristics (jitter, shimmer, CPP, HNR, $pF0{\cdot}F1{\cdot}F2{\cdot}F3$, sF0, sF4, sB1, $H1_{c/u}$, $A1_u$, $A3_c$, $H1A3_{c/u}$, $H1A1_u$). Twenty three females ($30{\pm}4.4$ years old) living in Seoul and Gyeonggi Province were participated in this study to answer the questionnaires and record their voice. The participants prolonged /a/ vowel for 5 seconds in a natural condition for their voice recording. Voice data were analyzed using the Matlab and Praat program. A t-test and a correlation analysis were conducted by using SPSS for the statistical analysis. The results are as follows. First, the BDI is significantly higher in group I (lurear phase contrast the menstrual period) and group II (follicular phase against the menstrual period) than group III (luteal phase for follicular phase) (p<.05). Second, shimmer, CPP, pF0 showed a statistically high correlation regarding the BDI in group I (lurear phase contrast the menstrual period). Voice parameters may be useful as supplement in evaluating the emotional change in the phase of menstrual cycle.

• Journal of the Semiconductor & Display Technology
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• v.17 no.3
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• pp.90-94
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• 2018

In this paper, we applied a three-level T-type inverter with the one more voltage level than two-level inverter. However, the three-level T-type inverter has a systematic problem with voltage unbalances. So neutral point control is essential. Therefore, the voltage unbalance problem of the three - phase inverter was confirmed to be controlled within 5V using the neutral point control algorithm in charge and discharge mode. In addition, total harmonic distortion was reduced in three phases (u phase, v phase, w phase) when neutral point control was performed in charging mode and also in three phases (u phase, v phase, w phase) in discharge mode. In this paper suggests a neutral point control algorithm to solve the voltage unbalance of a three-level T-type inverter, and shows the improvement of the performance of the proposed algorithm through experiment.

• Proceedings of the KIEE Conference
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• 2001.10a
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• pp.88-90
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• 2001

This paper proposes a driving scheme for 6/6 single-phase SRM. The driving scheme is very simple and inexpensive. By use of this scheme, simple power devices based on low switching losses enable to high efficiency SRM drive. Starting, One of the main problem in single-phase SRM is overcome by a new starling algorithm with one hall sensor and a parting magnet. The proposed single-phase SRM has a high efficiency and robust drive characteristics compared to that of a universal motor.

• Korean Chemical Engineering Research
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• v.56 no.2
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• pp.186-190
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• 2018

For the first time, the characteristics of solid circulation rate ($G_S$) were investigated in a three-phase (gas-liquid-solid) viscous circulating fluidized bed (TPCFB). The solid circulation rate was controlled separately by adjusting the experimental apparatus as well as operating variables. Effects of primary and secondary liquid velocities ($U_{L1}$ and $U_{L2}$), gas velocity ($U_G$), particle size ($d_p$), height of particles piled up in the solid recycle device (h), and viscosity of continuous liquid media (${\mu}_L$) on the value of $G_S$ were determined. The experimental results showed that the value of $G_S$ increased with increases in the values of $U_{L1}$, $U_{L2}$, h and ${\mu}_L$, while it decreased with increasing $U_G$ and $d_p$ in TPCFBs with viscous liquid media. The values of $G_S$ were well correlated in terms of dimensionless groups within this experimental conditions.

• Proceedings of the KIEE Conference
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• 1988.11a
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• pp.21-23
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• 1988

Microstepping drive of 3 phase VR step motor with 2 phase exciting scheme is proposed. Considering the presence of harmonic components of inductance, the current reference is calculated. The experimental results show high accuracy of divided step position and resonance or instability in operating range.

• Archives of Pharmacal Research
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• v.28 no.6
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• pp.685-690
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• 2005

We recently reported that the ginseng saponin metabolite, compound K (20-O-$\beta$-D-glucopyra-nosyl-20(S)-protopanaxadiol, IH901), inhibits the growth of U937 cells through caspase-dependent apoptosis pathway. In this study, we further characterized the effects of compound K on U937 cells and found that, in addition to apoptosis, compound K induced the arrest of the G1 phase. The compound K treated U937 cells showed increased p21 expression; an inhibitory protein of cyclincdk complex. The up-regulation of p21 was followed by the inactivation of cyclin D and the cdk4 protein, which act at the early $G_1$ phase, and cyclin E, which acts at the late $G_1$ phase. Furthermore, compound K induced the activation of JNK and the transcription factor AP-1, which is a downstream target of JNK. These findings suggest that the up-regulation of p21 and activation of JNK in the compound K treated cells contribute to the arrest of the $G_1$ phase.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1997.11a
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• pp.68-72
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• 1997

In this paper, to obtain the YbB $a_2$C $u_3$ $O_{x}$ superconductor, the mixed Powders of Y $b_2$ $O_3$, BaC $O_3$, CuO and Y $b_2$BaCu $O_{5}$, BaCu $O_2$ were used and the various calcining conditions were applied for the 123 phase of YbB $a_2$C $u_3$ $O_{x}$. Samples were prepared by the mixed oxide method and calcined with various temperatures of 88$0^{\circ}C$ ~91$0^{\circ}C$ . It was observed that the distribution of YbB $a_2$C $u_3$ $O_{x}$ phase which was calcined at 90$0^{\circ}C$ for 12 hours and 99 hours. But the result of long time calcination(99 hrs), the 123 phase of YbB $a_2$C $u_3$ $O_{x}$ was existed between 89$0^{\circ}C$ and 91$0^{\circ}C$ . And the best case could be obtained at the calcination temp. of 90$0^{\circ}C$ from the mixed Powder of YbB $a_2$C $u_3$ $O_{5}$ and Bacu $O_2$ which were prepared individually.idually.