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http://dx.doi.org/10.5573/ieie.2017.54.7.115

Optimal Echo phase of FLASH sequence for Brain Enhancement scan of mouse at 9.4T MRI system  

Jeong, Hyunkeun (Bio-Medical Science, Korea University Graduate School)
Kim, Mingi (Electronics&Information Engineering, Korea University)
Nam, Kichang (Department of Medical Engineering, Dongguk University College of Medicine)
Jung, Hyundo (Criminal Psychology, Templeton University)
Ahn, Chigwon (Department of Treatment, KH-JS Oriental Medicine Clinic)
Kim, Hochul (Department of Radiological Science, Eulji University)
Publication Information
Journal of the Institute of Electronics and Information Engineers / v.54, no.7, 2017 , pp. 115-124 More about this Journal
Abstract
The objective of study was to investigate the optimal echo phase for mouse brain enhancement scan using fast low angle shot (FLASH) sequence of 9.4T magnetic resonance imaging (MRI). For quantification based on this method, an MR phantom experiment and clinical research were done. The phantom experiment was conducted by fabricating three phantoms with different molar concentration of gadolinium to create changes in echo phase of 9.4T FLASH sequence used in mouse brain scans. In the phantom experiment, SSI was 25~27 [arbitrary units, a.u.] in each of 33 phases from $6{\pi}$ to $28{\pi}$, while RSP was 30~100 mmol. MPSI was 47~52 [a.u], while MPP, where MPSI is seen, was 0.8~9 mmol. EPMS was 80.8~108.0%, while ASIMP was formed between 21.1 and 31.8 [a.u]. In the clinical research, Finally, the occurrence rate of artifact that expressed -1 nd +1. The present study was able to quantify the degree of enhancement at FLASH sequence of 9.4T MRI, as well as identify the optimal echo phase during mouse brain enhancement scan.
Keywords
9.4T MRI; FLASH; mouse brain; Gadoteridol; GBCA;
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Times Cited By KSCI : 5  (Citation Analysis)
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