• Title/Summary/Keyword: Treatment Efficacy

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Efficacy of Aqueous Chlorine Dioxide and Citric Acid in Reducing Escherichia coli on the Radish Seeds Used for Sprout Production

  • Lim, Jeong-Ho;Jeong, Jin-Woong;Kim, Jee-Hye;Park, Kee-Jai
    • Food Science and Biotechnology
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    • v.17 no.4
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    • pp.878-882
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    • 2008
  • The efficacy of citric acid-aqueous chlorine dioxide ($ClO_2$) treatment of radish seeds artificially contaminated with Escherichia coli was studied. Radish seeds were inoculated with E. coli. Following inoculation, samples were stored at $4^{\circ}C$ and soaked in citric acid or aqueous $ClO_2$ for 10 min. The treatment of radish seeds using 200 ppm aqueous $ClO_2$ solution caused a 1.5 log CFU/g reduction in the population of E. coli. Compared to the aqueous $ClO_2$ treatment, soaking radish seeds in 2.0% citric acid solution for 10 min was more effective in reducing E. coli populations on radish seeds. The efficacy of spray application of chlorine (100 ppm) or 0.5% citric acid to eliminate E. coli during the germination and growth of radish was investigated. Radish seed inoculated with E. coli was treated for the duration of the growth period. Although it resulted in a decrease in the E. coli population, the spray application of 100 ppm chlorine during the growth period was not significantly effective. In contrast, the combined treatment of seeds using 200 ppm aqueous $ClO_2$ and treatment of sprouts with 0.5% citric acid solution during sprout growth was hardly effective in eliminating E. coli.

In vivo and in vitro efficacy of florfenicol, terbinafine, and mometasone furoate topical otic solution for the treatment of canine otitis externa

  • Bae, Seulgi;Jin, Yunseok;Oh, Taeho
    • Korean Journal of Veterinary Research
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    • v.61 no.4
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    • pp.37.1-37.6
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    • 2021
  • This study evaluated the efficacy of a new, single-dose otic solution combining florfenicol, terbinafine, and mometasone furoate for the treatment of canine otitis externa (OE) in vitro and in vivo. Forty-one client-owned dogs with OE were included in the study and divided into a treatment group that received the test solution and a negative control group that received a normal saline solution. On day 0, the dogs were treated either with the test or the control solution and evaluated over 30 days. Clinical efficacy was evaluated by clinical signs and cytological organism counts. In vitro antimicrobial susceptibility was evaluated by the minimum inhibitory concentration (MIC). After treatment with the test solution, clinical signs continuously decreased and cytological scores were significantly reduced. The results of MIC testing showed that the test solution was potent against the common pathogenic causes of canine OE. In this study, the most common causative pathogens were Staphylococcus pseudintermedius, Pseudomonas spp. and Malassezia pachydermatis. No issues related to safety were identified. Based on these results, this new ototopical drug can be used as first line treatment for canine OE.

The Effects of a Epilepsy Education Program on Self Efficacy and Self Management in Patients with Epilepsy (간질교육 프로그램이 성인 간질환자의 자기효능과 자기관리에 미치는 효과)

  • 박영숙
    • Journal of Korean Academy of Nursing
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    • v.29 no.2
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    • pp.405-417
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    • 1999
  • The purpose of this study was to test the effects of a epilepsy education program as a nursing intervention for patients with epilepsy. A quasi treatment research (non equivalent control group pretest-posttest design) was used in this study. The subjects were 40 epilepsy patients visiting an outpatient department of a general hospital in Daegu city.(treatment group : 20 patients, control group : 20 patients). The study was carried out from June, 1998 to September, 1998. Data was collected before the education program (pretest), immedately after(posttest 1) and 4 weeks later(posttest 2) and were analyzed with repeated measures ANOVA, t-test, Chi-sqare test and Pearson correlation coefficient. The results are as follows : There was a significant difference in epilepsy self efficacy between two groups(F=26.27, p=.000). There was a significant difference according to pretest, posttest 1 and posttest 2(F=111.20, p=.000), and interaction effect between treatment and time(F=109.42, p=.000). There was a significant difference in epilepsy self management between two groups(F=78.02, p=.000). There was a significant difference according to pretest, posttest 1 and posttest 2 test(F=94.02, p=.000), and interaction effect between treatment and time(F=88.14, p=.000). There was a significant correlation(r=.76, p=.000) between epilepsy self efficacy and epilepsy self management. These results suggest that a epilepsy education program is effective ill promoting self efficacy and self management of the patient with epilepsy. Thus this program can be recommended as an effective nursing intervention for the epilepsy patients.

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The perception of a nail beautician according to the nail treatment technique Job efficacy and job satisfaction (네일 시술기법에 따른 네일 미용인이 지각하는 직무 효능감 및 직무만족도)

  • Park, Jang-Soon
    • Journal of the Korea Convergence Society
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    • v.13 no.3
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    • pp.301-307
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    • 2022
  • Excessive work intensity and stress from customers visiting nail salons due to the increase in the frequency of visits and treatments to nail salons of modern people are negatively affecting the job psychology of nail salons. Accordingly, according to the need to prepare realistic and specific measures to increase job efficacy and job satisfaction through nail treatment techniques of nail salons, the perceived job efficacy and job This study was conducted based on the research model and hypothesis for satisfaction. As a result of the study, it was found that the nail gradation technique induces the highest job efficacy of nail polishers, and it was found that the more gel manicure techniques were applied, the higher the job satisfaction of nail polishers was. Through this study, it is expected that the complex application between various nail techniques will be possible and the coordinates of the job psychology of nail beauticians will be presented, and at the same time, it will serve as basic data for improving the work environment and developing new nail treatment techniques.

Review on the Efficacy and Safety of Mahuang and Ephedrine in the Treatment of Obesity -Focused on RCT- (비만 치료에서 마황 및 에페드린의 유효성, 안전성에 대한 고찰 - RCT 연구를 중심으로 -)

  • Jo, Ga-Won;Ok, Ji-Myung;Kim, Seo-Young;Lim, Young-Woo
    • The Journal of Korean Medicine
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    • v.38 no.3
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    • pp.170-184
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    • 2017
  • Objectives: The objective of this study was to summarize randomized clinical trials (RCTs) that have assessed efficacy and safety of mahuang and ephedrine on treatment of obesity and to propose better process of study. Methods: NLM Medline (pubmed), the Cochrane library, Scopus, Science Direct, RISS, KISS were systemically searched for clinical trials investigating the efficacy, safety of mahuang and ephedrine on treatment of obesity from 2000 to 2017. Results: 16 RCTs met all the inclusion criteria. In most reports, mahuang and ephedrine significantly reduced body weight, body fat mass. There were no serious adverse events associated with mahuang and ephedrine in all studies. Conclusions: In appropriate dose of mahuang and ephedrine for healthy adult was safe, and weight loss effect of mahuang and ephedrine was better than control group. Improved clinical practice guidelines should be developed for safe use of mahuang and ephedrine.

Effect of Emergency Treatment Education Program for Self-leadership, Career Decision Making Self Efficacy and Nursing Performance Ability of Nursing Students (응급처치 교육프로그램이 간호대학생의 셀프리더십, 진로결정자기효능감 및 수행능력에 미치는 영향)

  • Do, Eun-Su;Kim, Soon-Gu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.636-644
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    • 2018
  • This study was conducted to examine the effects of an emergency treatment education program on nursing students' self-leadership, career decision-making self-efficacy, and nursing performance ability. The study was designed using a nonequivalent control group pretest-posttest design, and data were collected from June 1 to August 31, 2017. The participants consisted of 52 nursing students in D College of D City who were assigned to an experimental group (n=27) or control group (n=25). The pretest poll was performed on June 1, 2017 and posttest poll was performed 2 weeks later without any treatment in the control group. In the experimental group, the pretest poll was performed on July 25 before the emergency treatment education program and the posttest poll was performed on August 31 after the education program. The emergency treatment education program for the experimental group consisted of 2 hours of emergency treatment instruction, autonomously watching videos, and 4 hours of teaching elementary students about CPR for adults and first aid for airway obstruction, burns, bleeding, and fractures as a lecturer. The data were analyzed using descriptive analysis, independent t-test, $x^2$ test, and paired t-test with SPSS/WIN 20.0. After receiving the emergency treatment education program, a difference was observed in self-leadership (t=2.08, p<.05), career decision-making self-efficacy (t=4.22, p<.05) and nursing performance ability (t=5.02, p<.05) in the experimental group. The results of this study indicate that the emergency treatment education program was effective at increasing self-leadership, career decision-making self-efficacy, and nursing performance ability in nursing students.

Safety, efficacy, and onset of a novel botulinum toxin type A (Nabota) for the treatment of glabellar frown lines: a single-arm, prospective, phase 4 clinical study

  • Song, Sinyoung;Lee, Yeon Hoon;Hong, Joon Pio;Oh, Tae Suk
    • Archives of Craniofacial Surgery
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    • v.19 no.3
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    • pp.168-174
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    • 2018
  • Background: Safety, efficacy, and time to onset of effect of botulinum toxin type A is of importance to persons who seek improvement in glabellar frown lines, but this has not been well studied. The aim of this study was to determine the safety, efficacy, and onset of action of a newly developed botulinum toxin type A (Nabota) for the treatment of glabellar frown lines. Methods: This was a single-arm, open-label, and phase 4 clinical study. Forty-two subjects with glabellar lines were treated with five times of intramuscular injection of 0.1 mL (4 U/0.1 mL) for a total of 20 U of Nabota. Efficacy and safety were assessed at 2, 3, 4, 5, and 14 days. Efficacy was assessed by the investigator and it was defined as a 1-point change on a 4-point scale. Results: Improvement in glabellar frown lines at maximum frown was observed in 85.4% of subjects 2 days after administration. Improvement in glabellar lines at rest was observed in 51.2% of subjects 2 days after administration, and the proportion of subjects showing improvement increased with time. No severe adverse events were recorded. Conclusion: Onset of action was observed in the majority of subjects by 2 days after administration of Nabota. In addition, Nabota was found to be safe and effective for the treatment of glabellar frown lines.

Non-Stimulant Medications in the Treatment of Attention-Deficit Hyperactivity Disorder (주의력결핍 과잉행동장애에서 비정신자극제 약물치료)

  • Hwang, Jun-Won
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.19 no.2
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    • pp.72-82
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    • 2008
  • The aim of this paper is to evaluate the use of non-stimulants, including atomoxetine, bupropion and modafinil, as alternative approaches to the treatment of children with attention-deficit hyperactivity disorder. A comprehensive review of the empirically based literature regarding the efficacy and the safety of the non-stimulants was performed. There is a large and increasing body of data supporting the efficacy and the safety of non-stimulants. Although the treatment effect sizes for non-stimulants may be smaller than those for stimulants, non-stimulants alone have been shown to be effective in the treatment of attention-deficit hyperactivity disorder as well as several comorbidities. These results suggest that non-stimulants are effective in the treatment of attention-deficit hyperactivity disorder. Further studies are needed to improve our understanding of alternative pharmacological medications in the treatment of attention-deficit hyperactivity disorder.

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The Effect of a Group Program Designed to Resolve the Psychological Career Barriers of University Freshmen on Their Psychological Career Barriers, Self-Efficacy in Career Decision-Making, and Self-Determination (대학 신입생을 위한 심리적 진로장벽 해소 집단프로그램이 심리적 진로장벽, 진로결정 자기효능감과 자기결정성에 미치는 효과)

  • Lee, Mi-Young
    • Journal of Digital Convergence
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    • v.16 no.10
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    • pp.485-496
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    • 2018
  • This study set out to organize and apply a group program designed to resolve the psychological career barriers of university freshmen and test its effects on their psychological career barriers, self-efficacy in career decision-making, and self-determination. For this purpose, the investigator divided the subjects into a treatment group of eight and a comparison group of nine, implemented a group program designed to resolve psychological career barriers over seven sessions, and applied no treatment to the comparison group. In an effort to examine the program's effects, the investigator conducted tests on psychological career barriers, self-efficacy in career decision-making, and self-determination in the pre- and post-test both in the treatment and comparison groups and examined the differences between them. The findings were as follows: first, the treatment group made a significant decrease to its psychological career barriers scores compared to the comparison group; second, the treatment group made a significant increase to its self-efficacy in career decision-making scores compared to the comparison group; and finally, the treatment group also made a significant increase to its self-determination scores compared to the comparison group with a significant enhancement. That is, the program was effective for lowering the psychological career barriers of university freshmen and improving their self-efficacy in career decision-making and self-determination. The study also discusses the utilization of its findings and future study.

Effect of Compensation System on Job Satisfaction for Care-Workers - Focused on the Mediating Effect of Self-efficacy - (요양보호사의 보상체계가 직무만족도에 미치는 영향 - 자기효능감 매개 효과 중심으로 -)

  • Jang, Seon-Ah;Ko, Jeong-hoon
    • The Journal of the Korea Contents Association
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    • v.21 no.4
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    • pp.473-486
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    • 2021
  • The purpose of this study is to investigate the mediating effect on self-efficacy in the effect of the compensation system of caregivers on job satisfaction. The research method was analyzed with SPSS V22.0 on the data of 367 people surveyed of caregivers working at home welfare facilities and elderly care facilities in the metropolitan area. The result is as follows. First, it was found that the average monthly salary, satisfaction of compensation treatment, and fairness of compensation had a positive effect on job satisfaction in the compensation system of caregivers. Second, in the compensation system for care givers, it was found that monthly average salary, satisfaction with compensation treatment, and compensation process had a positive effect on self-efficacy. Third, it was found that the self-efficacy of caregivers had a positive effect on job satisfaction. Fourth, in the compensation system of caregivers, it was found that the monthly average salary, compensation treatment satisfaction, and compensation process had an effect on job satisfaction, whereas self-efficacy had a positive mediating effect. It revealed that the higher the average monthly salary, compensation treatment satisfaction, and compensation process in the caregiver's compensation system, the more positively the self-efficacy had, and this self-efficacy had a positive effect on the job satisfaction of the caregiver.