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Study on bisphosphonate-related osteonecrosis of the jaw (BRONJ): case report and literature review (비스포스포네이트 관련 악골괴사에 대한 연구: 증례보고 및 문헌문석)

  • Kim, Yeo-Gab;Lee, Baek-Soo;Kwon, Yong-Dae;Suh, Joon-Ho;Jeen, Sang-Mi
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.36 no.4
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    • pp.291-302
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    • 2010
  • Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of Bisphosphonates (BPs) use. These days, oral bisphosphonates are normally prescribed to treat osteoporosis. Intravenous BPs are used extensively to treat osteolytic bone lesions related to multiplemyeloma and bone metastasis of solid cancers, breast cancer or prostate cancer. As the prescription of BPs is universalized and the number of people treated with BPs is increasing, an accurate understanding and proper management of BRONJ are required. The aim of this study was to improve the clinicians' understanding of BRONJ by reviewing the literature. To achieve this, this paper introduces case reports as well as the current concept of BRONJ based on the 2009 updates by American Association of Oral and Maxillofacial (AAOMS) including the definition, epidemiology, etiology, diagnosis, treatment and prevention of BRONJ.

Reviewing Research on the Treatment and Study of Fracture in Korean Journals Objective - Focus on Domestic Thesis (골절의 한의학적 치료 및 연구에 관한 논문 고찰 - 국내 논문을 중심으로)

  • Bae, Kil-Joon;Jeong, Ji-Won;Jung, Min-Young;Kim, Seon-Jong
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.3
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    • pp.27-36
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    • 2015
  • Objectives The aim of this review is to analyze research trends on the Korean medical treatment and study of fracture. Methods We searched 38 studies related treatment of fracture via Korean medicine web databases. We classified these studies by three types (experimental reports, case reports and retrospective reports) and researched how to treat the patient of fracture. Results 38 studies were published since 1993 and published every year since 2004 to 2013. There were 8 experimental reports, 20 case reports and 10 retrospective reports. Most of these studies were effective to treat of fracture. Bee venom treatment and Hua-Tuo-Jia-Ji-Xue acupuncture treatment were more effective than general treatment. Conclusions These results suggest that Korean medicine is effective treatment to fracture and we need continuously agonize and research more effective therapy method.

Analysis of Design Parameters For Shunt Valve and Anti-Siphon Device Used to Treat Patients with Hydrocephalus

  • Lee, Chong-Sun;Jang, Jong-Yun;Suh, Chang-Min
    • Journal of Mechanical Science and Technology
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    • v.15 no.7
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    • pp.1061-1071
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    • 2001
  • The present study investigated design parameters of shunt valves and anti-siphon device used to treat patients with hydrocephalus. The shunt valve controls drainage of cerebrospinal fluid (CSF) through passive deflection of a thin and small diaphragm. The anti-siphon device(ASD) is optionally connected to the valve to prevent overdrainage when the patients are in the standing position. The major design parameters influencing pressure-flow characteristics of the shunt valve were analyzed using ANSYS structural program. Experiments were performed on the commercially available valves and showed good agreements with the computer simulation. The results of the study indicated that predeflection of the shunt valve diaphragm is an important design parameter to determine the opening pressure of the valve. The predeflection was found to depend on the diaphragm tip height and could be adjusted by the diaphragm thickness and its elastic modulus. The major design parameters of the ASD were found to be the clearance (gap height) between the thin diaphragm and the flow orifice. Besides the gap height, the opening pressure of the ASD could be adjusted by the diaphragm thickness, its elastic modulus, area ratio of the diaphragm to the flow orifice. Based on the numerical simulation which considered the increased subcutaneous pressure introduced by the tissue capsule pressure on the implanted shunt valve system, optimum design parameters were proposed for the ASD.

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The case report of C.V.A. patient with M.V.H.D (C.V.A.환자(患者)의 심장판막질환(心臟瓣膜疾患)에 대한 증례보고(症例報考))

  • Kang, Min-Joo;Jung, Ji-Chun;Lee, Won-Chul
    • The Journal of Internal Korean Medicine
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    • v.14 no.1
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    • pp.43-54
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    • 1993
  • Observing after enforcing the medication and the acupuncture theraphy on the CVA patient sick with the cerebral embolus by organic pathology of the heart and whose desease was from heat symptoms caused by exessive pathogenic factors of which caused from affection due to exogeneous factors, we obtained the results as follows; 1. Serious condition could be relieved by removing acute symptoms according to the principle of the 'In emergency causes treat the acute symptoms first, when these being relieved treat it's fundament cause'. 2. The lesion could be disable for which the traditional medication theraphy through the differentiation of symptoms-complexes had removed the symptoms caused by organic pathology of heart. 3. The acupuncture stimulation through the differentiation of symptoms seemed to influence electric conduction system. Through this case, If we objectify the diagnosis and the medical treatment, the part of the curing diseases can progress more effectively.

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Evidence-based Screening, Early Diagnosis and Treatment Strategy of Cervical Cancer for National Policy in Low-resource countries: Example of India

  • Saxena, Upma;Sauvaget, Catherine;Sankaranarayanan, Rengaswamy
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1699-1703
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    • 2012
  • Cervical cancer remains the most frequent cancer in women from the developing world. More than 88% of deaths occur in low-income countries, and it is predicted to climb to 91.5% by 2030. Although Pap-based screening programmes have shown to be effective in reducing the disease burden in high-resource countries, implementation and sustention of cytology-based programmes is quite challenging in low-resource settings. The present paper reviews evidence-based alternatives of screening methods, triaging algorithm, treatment of cervical precancerous lesions, and age-group at screening appropriate for low-income countries. Evidence shows that visual inspection methods using diluted acid acetic or Lugol's iodine, and HPV-DNA testing are more sensitive tests than the Pap-smear screening test. Visual inspection allows an immediate result and, when appropriate, may be immediately followed by cryotherapy, the so called "screen-and-treat" approach, achieved in a single visit, by trained nurses and midwives. Examples of cervical cancer prevention programmes in India and selected low-income countries are given.

Effectiveness of a Brief Physician Counselling Session on Improving Smoking Behaviour in the Workplace

  • Han, Yung Wen;Mohammad, Mohazmi;Liew, Su May
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7287-7290
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    • 2014
  • Background: Brief physician counselling has been shown to be effective in improving smokers' behaviour. If the counselling sessions can be given at the workplace, this would benefit a larger number of smokers. This study aimed to determine the effectiveness of a ten-minute physician counseling session at the workplace in improving smoking behaviour. Materials and Methods: This prospective randomised control trial was conducted on smokers in a factory. A total of 163 participants were recruited and randomised into control and intervention groups using a table of random numbers. The intervention group received a ten-minute brief physician counselling session to quit smoking. Stages of smoking behaviour were measured in both groups using a translated and validated questionnaire at baseline, one month and three months post intervention. Results: There was a significant improvement in smoking behaviour at one-month post intervention (p=0.024, intention to treat analysis; OR=2.525; CI=1.109-5.747). This was not significant at three-month post intervention (p=0.946, intention to treat analysis; OR=1.026; 95% CI=0.486-2.168). Conclusions: A session of brief physician counselling was effective in improving smokers' behaviour at workplace, but the effect was not sustained.

Four cases of Soyangins vitiligo patients gotten better by Oriental medical treatment who have the symptoms in the hands (소양인 수부 백반증 한방치험 4례)

  • Hong, Yo-Han;Kim, Sung-Won;Cho, Young-Chen
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.28 no.1
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    • pp.152-159
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    • 2015
  • Purpose : This rearch aims to prove effects of an oriental medical complex therapy on vitiligo patients who have the symptoms in the hands. Method : The rearch conducted its investigation targeting these four patients who have the symptoms in the hands. The study resolved the findings through the comparison on the pictures before and after the therapy. Result : After making a comparison on the pictures, the study confirmed positive changes in the conditions of the patients. The oriental medical complex therapy turned out to be effective enough to treat the patients who have the symptoms in the hands. Conclusion : Such result leads the study to a conclusion that the oriental medical complex therapy can be an effective method to treat these patients who have the symptoms in the hands. In addition, more case studies and research will be necessary.

A Alcoholic Liver Disease Patient Case with Diabetes Mellitus (당뇨병에 병발한 알코올성 간질환의 치험례)

  • Kim, Dong-Woo;Jun, Chan-Yong;Han, Yang-Hee;Park, Jong-Hyeong;Yeo, Eun-Kyoung
    • The Journal of Internal Korean Medicine
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    • v.21 no.4
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    • pp.649-653
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    • 2000
  • We had applied Saenggangunbitang, Gamijihwangtang, and Saenggangunbitang-Gamijihwangtang on a alcoholic liver disease patient with diabetes mellitus, Saenggangunbitang has been used to treat alcoholic liver disease and had known to have beneficial effects. Gamijihwangtang has been used to treat Yin deficiency syndrome in Orient Medicine. We observed clinical symptom, liver function, nutritional state and blood sugar. After first administration, Clinical symptom and blood sugar were improved by Gamijihwangtang medication. Alter second administration, Clinical symptom, blood sugar and liver function were improved by Saenggangunbitang-Gamijihwangtang medication. After third administration, clinical symptom and liver function were improved by Saenggangunbitang medication. It is possibly suggested that Saenggangunbitang-Gamijihwangtang medication has a therapeutic effect on alcoholic liver disease with diabetes mellitus.

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An attitude control of stabilizing system using indirect adaptive fuzzy control

  • Kim, Jae-Hoon;Kim, Jong-Hwa
    • Journal of Advanced Marine Engineering and Technology
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    • v.38 no.10
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    • pp.1318-1326
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    • 2014
  • The purpose of a tracking control system is to track a moving target and to find the exact information of the target. If the platform of the tracking control system is equipped on a moving vehicle such as a ship, the tracking control system will treat even the additional platform motion. In order to avoid the complexity comprising the tracking control system, a process to treat the platform motion, named stabilizing system, must be separated from the tracking control system. In this paper, a method to comprise an attitude control system for the platform stabilization is proposed using an adaptive fuzzy control which is applicable to the system with structural and parametric uncertainty. The suggested adaptive fuzzy control algorithm is the 2nd/1st-type indirect adaptive fuzzy control algorithm using the advantages of 1st-type and 2nd-type indirect adaptive fuzzy control algorithm. Several experiments using the implemented stabilizing system are executed for verifying the effectiveness of the suggested method.

Integrated Communication Design Strategies for the Revised Marketing Environment (마케팅환경 변화에 따른 통합커뮤니케이션디자인 전략)

  • Yang, Jae-Bum
    • The Journal of the Korea Contents Association
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    • v.8 no.5
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    • pp.113-121
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    • 2008
  • Researcher tried to argue the possibility of application of visual communication design adapting the marketing environment change on this paper. What is ICD (Integrated Communication Design)? This is a new attempt to treat these common marketing methods, such as, C, I, B, I, TV commercials, newspaper commercials, posters, brochures, DM, package designing, POP, outdoor visual information, web sites etc, as a whole. And no longer treat them as separate pieces as we were doing previously. So I started this research with positive analysis which already has been theoretically discussed based on the documents and researches on the same subject. Through this attempt I tried to examine the possibility of application of ICD. Conclusively, I developed and suggest named the ICD model, by which we could explain the current marketing communication design effort more holistically then ever.