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http://dx.doi.org/10.5125/jkaoms.2010.36.4.291

Study on bisphosphonate-related osteonecrosis of the jaw (BRONJ): case report and literature review  

Kim, Yeo-Gab (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University)
Lee, Baek-Soo (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University)
Kwon, Yong-Dae (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University)
Suh, Joon-Ho (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University)
Jeen, Sang-Mi (School of Dentistry, Kyung Hee University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.36, no.4, 2010 , pp. 291-302 More about this Journal
Abstract
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of Bisphosphonates (BPs) use. These days, oral bisphosphonates are normally prescribed to treat osteoporosis. Intravenous BPs are used extensively to treat osteolytic bone lesions related to multiplemyeloma and bone metastasis of solid cancers, breast cancer or prostate cancer. As the prescription of BPs is universalized and the number of people treated with BPs is increasing, an accurate understanding and proper management of BRONJ are required. The aim of this study was to improve the clinicians' understanding of BRONJ by reviewing the literature. To achieve this, this paper introduces case reports as well as the current concept of BRONJ based on the 2009 updates by American Association of Oral and Maxillofacial (AAOMS) including the definition, epidemiology, etiology, diagnosis, treatment and prevention of BRONJ.
Keywords
Bisphosphonate; Osteonecrosis; Osteoporosis; Jaw diseases;
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Times Cited By KSCI : 3  (Citation Analysis)
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