• Title/Summary/Keyword: Three-loop

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Modified Urethral Graciloplasty Cross-Innervated by the Pudendal Nerve for Postprostatectomy Urinary Incontinence: Cadaveric Simulation Surgery and a Clinical Case Report

  • Hisashi Sakuma;Masaki Yazawa;Makoto Hikosaka;Yumiko Uchikawa-Tani;Masayoshi Takayama;Kazuo Kishi
    • Archives of Plastic Surgery
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    • v.50 no.6
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    • pp.578-585
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    • 2023
  • An artificial sphincter implanted in the bulbous urethra to treat severe postprostatectomy urinary incontinence is effective, but embedding-associated complications can occur. We assessed the feasibility, efficacy, and safety of urethral graciloplasty cross-innervated by the pudendal nerve. A simulation surgery on three male fresh cadavers was performed. Both ends of the gracilis muscle were isolated only on its vascular pedicle with proximal end of the obturator nerve severed and transferred to the perineum. We examined whether the gracilis muscle could be wrapped around the bulbous urethra and whether the obturator nerve was long enough to suture with the pudendal nerve. In addition, surgery was performed on a 71-year-old male patient with severe urinary incontinence. The postoperative 12-month outcomes were assessed using a 24-hour pad test and urodynamic study. In all cadaveric simulations, the gracilis muscles could be wrapped around the bulbous urethra in a γ-loop configuration. The length of the obturator nerve was sufficient for neurorrhaphy with the pudendal nerve. In the clinical case, the postoperative course was uneventful. The mean maximum urethral closure pressure and functional profile length increased from 40.7 to 70 cm H2O and from 40.1 to 45.3 mm, respectively. Although urinary incontinence was not completely cured, the patient was able to maintain urinary continence at night. Urethral graciloplasty cross-innervated by the pudendal nerve is effective in raising the urethral pressure and reducing urinary incontinence.

Overview of separate effect and integral system tests on the passive containment cooling system of SMART100

  • Jin-Hwa Yang;Tae-Hwan Ahn;Hong Hyun Son;Jin Su Kwon;Hwang Bae;Hyun-Sik Park;Kyoung-Ho Kang
    • Nuclear Engineering and Technology
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    • v.56 no.3
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    • pp.1066-1080
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    • 2024
  • SMART100 has a containment pressure and radioactivity suppression system (CPRSS) for passive containment cooling system (PCCS). This prevents overheating and over-pressurization of a containment through direct contact condensation in an in-containment refueling water storage tank (IRWST) and wall condensation in a CPRSS heat exchanger (CHX) in an emergency cool-down tank (ECT). The Korea Atomic Energy Research Institute (KAERI) constructed scaled-down test facilities, SISTA1 and SISTA2, for the thermal-hydraulic validation of the SMART100 CPRSS. Three separate effect tests were performed using SISTA1 to confirm the heat removal characteristics of SMART100 CPRSS. When the low mass flux steam with or without non-condensable gas is released into an IRWST, the conditions for mitigation of the chugging phenomenon were identified, and the physical variables were quantified by the 3D reconstruction method. The local behavior of the non-condensable gas was measured after condensation inside heat exchanger using a traverse system. Stratification of non-condensable gas occurred in large tank of the natural circulation loop. SISTA2 was used to simulate a small break loss-of-coolant accident (SBLCOA) transient. Since the test apparatus was a metal tank, compensations of initial heat transfer to the material and effect of heat loss during long-term operation were important for simulating cooling performance of SMART100 CPRSS. The pressure of SMART100 CPRSS was maintained below the design limit for 3 days even under sufficiently conservative conditions of an SBLOCA transient.

A Loop-mediated Isothermal Amplification Method for White-backed Planthopper-specific Detection (고리매개등온증폭법(LAMP)을 이용한 흰등멸구 특이 판별법)

  • Seo, Bo Yoon;Park, Chang Gyu;Jung, Jin Kyo;Cho, Jumrae;Lee, Gwan-Seok;Kim, Kwang-Ho
    • Korean journal of applied entomology
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    • v.57 no.4
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    • pp.393-399
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    • 2018
  • A loop-mediated isothermal amplification (LAMP) primer set (WBPH-65) was designed for the species-specific detection of white-backed planthopper (WBPH) Sogatella furcifera based on the full-length sequence of the internal transcribed spacer 2 (ITS2) (KC417469.1). The WBPH-65 primer set consists of six primers (total 165 bp), F3 (18 bp), B3 (18 bp), FIP (43 bp), BIP (40 bp), LF (21 bp), and LB (25 bp). After the LAMP reaction of three rice planthoppers, S. furcifera, Nilaparvata lugens, and Laodelphax striatellus, with the WBPH-65 primer set for 60 min at $65^{\circ}C$, the LAMP products were observed in the genomic DNA of S. furcifera only. According to the DNA amount of S. furcifera and incubation duration at $65^{\circ}C$, the difference of fluorescence relative to the negative control (0 ng) was clearly observed in a 40-min incubation with 10 and 100 ng or in case of 60-min incubation with 0.01, 0.1, 1, 10, and 100 ng. There was little difference in fluorescence between the negative control and all the other DNAs tested in 20- and 30-min incubations. On the other hand, the WBPH-65 primer set without LF and LB primers showed little amplification in the genomic DNAs of the three rice planthoppers, S. furcifera, N. lugens, and L. striatellus in a 60-min incubation. These results suggest that all six primers (F3, B3, FIP, BIP, LF, and BF) are necessary for the WBPH-65 primer set to detect S. furcifera within a 60-min incubation, and is able to discriminate S. furcifera from at least N. lugens and L. striatellus.

Monitoring the Reoccurrence of Fire Blight and the Eradication Efficiency of Erwinia amylovora in Burial Sites of Infected Host Plants Using Sentinel Plants (미끼식물을 이용한 화상병 감염 기주 매몰지 내 화상병균 제거 효율 검증 및 병 재발 모니터링)

  • In Woong, Park;Yu-Rim, Song;Nguyen Trung, Vu;Eom-Ji, Oh;In Sun, Hwang;Hyeonheui, Ham;Seong Hwan, Kim;Duck Hwan, Park;Chang-Sik, Oh
    • Research in Plant Disease
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    • v.28 no.4
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    • pp.221-230
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    • 2022
  • The fire blight caused by Erwinia amylovora (Ea) was first reported in 2015 in Korea, and the disease has rapidly spread to 22 regions until 2021. In Korea, all host plants in the apple and pear orchards where fire blight occurred should be eliminated and buried by the Plant Protection Act. To prevent the spread of the disease, all burial sites were prohibited from planting the new host plants for the next three years. To confirm the eradication efficiency of Ea and the reoccurrence of fire blight, the surveillance facilities were established on three burial sites from 2019 to 2020 in Anseong-si, Gyeonggi-do, and Chungju-si, Chungcheongbuk-do. As host plants, five apple trees of fire blight-susceptible cultivar 'Fuji', were planted in each facility. All facilities were enclosed with fences and nets and equipped with two CCTVs, motion sensors, and several other sensors for recording weather conditions to monitor the environment of the sentinel plants in real-time. The sentinel plants were checked for the reoccurrence of fire blight routinely. Suspicious plant parts were collected and analyzed for Ea detection by loop-mediated isothermal amplification polymerase chain reaction and conventional polymerase chain reaction. Until November 2022, Ea has not been detected in all sentinel plants. These results might support that the burial control of infected plants in soil works efficiently to remove Ea and support the possibility to shorten the prohibition period of host plant establishment in the burial sites.

A Design of Wide-Range Digitally Controlled Oscillator with an Active Inductor (능동 인덕터를 이용한 광대역 디지털 제어 발진기의 설계)

  • Pu, Young-Gun;Park, An-Soo;Park, Hyung-Gu;Park, Joon-Sung;Lee, Kang-Yoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.48 no.3
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    • pp.34-41
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    • 2011
  • This paper presents a wide tuning range, fine-resolution DCO (Digitally Controlled Oscillator) with an active inductor. In order to control the frequency of the DCO, the transconductance of the active inductor is tuned digitally. In addition, the DCO gain needs to be calibrated digitally to compensate for gain variations. To cover the wide tuning range, an automatic three-step coarse tuning scheme is proposed. The DCO total frequency tuning range is 1.4 GHz (2.1 GHz to 3.5 GHz), it is 58 % at 2.4 GHz. An effective frequency resolution is 0.14 kHz/LSB. The proposed DCO is implemented in 0.13 ${\mu}m$ CMOS process. The total power consumption is 6.6 mW from a 1.2 V supply voltage. The phase noise of the DCO output at 2.4 GHz is -120.67 dBc/Hz at 1 MHz offset.

From Broken Visions to Expanded Abstractions (망가진 시선으로부터 확장된 추상까지)

  • Hattler, Max
    • Cartoon and Animation Studies
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    • s.49
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    • pp.697-712
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    • 2017
  • In recent years, film and animation for cinematic release have embraced stereoscopic vision and the three-dimensional depth it creates for the viewer. The maturation of consumer-level virtual reality (VR) technology simultaneously spurred a wave of media productions set within 3D space, ranging from computer games to pornographic videos, to Academy Award-nominated animated VR short film Pearl. All of these works rely on stereoscopic fusion through stereopsis, that is, the perception of depth produced by the brain from left and right images with the amount of binocular parallax that corresponds to our eyes. They aim to emulate normal human vision. Within more experimental practices however, a fully rendered 3D space might not always be desirable. In my own abstract animation work, I tend to favour 2D flatness and the relative obfuscation of spatial relations it affords, as this underlines the visual abstraction I am pursuing. Not being able to immediately understand what is in front and what is behind can strengthen the desired effects. In 2015, Jeffrey Shaw challenged me to create a stereoscopic work for Animamix Biennale 2015-16, which he co-curated. This prompted me to question how stereoscopy, rather than hyper-defining space within three dimensions, might itself be used to achieve a confusion of spatial perception. And in turn, how abstract and experimental moving image practices can benefit from stereoscopy to open up new visual and narrative opportunities, if used in ways that break with, or go beyond stereoscopic fusion. Noteworthy works which exemplify a range of non-traditional, expanded approaches to binocular vision will be discussed below, followed by a brief introduction of the stereoscopic animation loop III=III which I created for Animamix Biennale. The techniques employed in these works might serve as a toolkit for artists interested in exploring a more experimental, expanded engagement with stereoscopy.

Effect of age on heart rate, blood lactate concentration, packed cell volume and hemoglobin to exercise in Jeju crossbreed horses

  • Kang, Ok-Deuk;Park, Yong-Soo
    • Journal of Animal Science and Technology
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    • v.59 no.1
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    • pp.2.1-2.6
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    • 2017
  • Background: This study aimed to analyze the on heart rate, blood lactate concentration, packed cell volume (PCV) and hemoglobin (Hb) response after conducting exercise in endurance horses. Methods: A total of 20 healthy 3-9-years-old Jeju crossbreed mares ($5.95{\pm}2.24$ year) of age and $312.65{\pm}13.59kg$ of weight) currently participating the endurance competition were used. The field tests selected for the experiment was gallop (approximately 8.3 m/s) along the selected 2.5 km course (a natural forest trail, not artificial road; a closed loop course). The horses were divided into three groups according to their age; 3-4 years of age (G1, $3.29{\pm}0.49$ year), 6-7 years of age (G2, $6.42{\pm}0.53$), and 8-9 years of age (G3, $8.50{\pm}0.55$). The measurements times for the heart rate, blood lactate concentration, PCV, and Hb analysis were conducted before exercise (T0), shortly after exercise (T1), 15 min after exercise (T2), and 30 min after exercise (T3), respectively. Data was analyzed using an analysis of covariance (ANCOVA) for repeated measures with times and groups. Results: The results of the comparison depending on the passage of rest time after exercise suggest that the heart rate and blood lactate concentration of three groups at T2 significantly decreased compared to T1 (p < 0.001). PCV of the G2 and G3 groups were significantly decreased at T2 compared to T1 (p < 0.01). Hb values at G2 (p < 0.01) and G3 (p < 0.001) groups were significantly decreased at T2 as compared to T1. However, heart rate, blood lactate concentration, PCV and Hb level at T1 showed no difference in the comparison of horses from different age groups with the exception of G3 group in terms of heart rate. Conclusion: The physiologic and hematological responses of horses during recovery time after 2,500 m exercise with gallop were no significant difference among the groups. These data are useful as a response evaluation method for training of endurance horses.

Visual Sensibility Evaluation of Fancy Yarns for Hand Knitting of using Computer Knitting Simulation -Application of SDS-ONE Paint Function- (Computer Knitting Simulation을 활용한 장식사 니트소재의 시각적 감성평가 -SDS-ONE의 Paint 기능 활용-)

  • Kim, Mi-Jin;Lee, Yoon-Mi;Kim, Young-Joo;Park, Myung-Ja
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.9
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    • pp.1333-1342
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    • 2008
  • This study intended to evaluate the visual sensibility of textiles of knitting simulation through the painting function of SDS-ONE, a computer knitting system, with the use of various fancy yarns for hand knitting. For this study, six kinds of fancy yarns with difference manufacturing style and form were selected: loop yarn, tamtam yarn, fur1 yarn, fur2 yarn, ladder yarn, and tape yarn. In order to create a computer knitting simulation, paint function of SDS-ONE was employed to scan the fancy yarns for hand knitting with a scanner. Then, after the registration of the yarns as data, the yarn was brought in for knitting simulation in plain stitch with 3 gauge. After that a survey was conducted involving 60 female experts in their twenties. Using SPSS 12.0, factor analysis, reliability, Pearson correlation coefficient, ANOVA, Duncan test, and regression analysis were performed to analyze the collected data. First, according to the result of analyzing the visual sense factor, three factors of the 'inflexibleness/ruggedness sense', 'lightweight sense', and 'smoothness sense' was extracted. According to the result of analyzing the visual sensibility factor, three factors of the 'activity', 'grace', and 'purity' was extracted. Second, With regard to preference and purchase intention, the knitted fabric with tamtam yarn(H2) was preferred than the other samples, indicating that the respondents had intention to purchase it. As for word-of-mouth intention, H2 ranked the first place, implying the respondents had intention to recommend it to other people. Third, the examination of the use of products each knitting simulation knit found that sweater and muffler are the most appropriate knit products. And H2 was the most suitable sample for sweater and muffler products. This study tried to prove that knit textile can be visually evaluated through a computer knitting simulation without the actual knitting and then to provide accurate data to related companies or the academic circle.

Hardware Design of High-Performance SAO in HEVC Encoder for Ultra HD Video Processing in Real Time (UHD 영상의 실시간 처리를 위한 고성능 HEVC SAO 부호화기 하드웨어 설계)

  • Cho, Hyun-pyo;Park, Seung-yong;Ryoo, Kwang-ki
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.10a
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    • pp.271-274
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    • 2014
  • This paper proposes high-performance SAO(Sample Adaptive Offset) in HEVC(High Efficiency Video Coding) encoder for Ultra HD video processing in real time. SAO is a newly adopted technique belonging to the in-loop filter in HEVC. The proposed SAO encoder hardware architecture uses three-layered buffers to minimize memory access time and to simplify pixel processing and also uses only adder, subtractor, shift register and feed-back comparator to reduce area. Furthermore, the proposed architecture consists of pipelined pixel classification and applying SAO parameters, and also classifies four consecutive pixels into EO and BO concurrently. These result in the reduction of processing time and computation. The proposed SAO encoder architecture is designed by Verilog HDL, and implemented by 180k logic gates in TSMC $0.18{\mu}m$ process. At 110MHz, the proposed SAO encoder can support 4K Ultra HD video encoding at 30fps in real time.

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The Immunological Position of Fibroblastic Reticular Cells Derived From Lymph Node Stroma (림프절 스트로마 유래 Fibroblastic Reticular Cell의 면역학적 위치)

  • Jong-Hwan Lee
    • Journal of Life Science
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    • v.34 no.5
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    • pp.356-364
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    • 2024
  • Lymph nodes (LNs) are crucial sites where immune responses are initiated to combat invading pathogens in the body. LNs are organized into distinctive compartments by stromal cells. Stromal cell subsets constitute special niches supporting the trafficking, activation, differentiation, and crosstalk of immune cells in LNs. Fibroblastic reticular cells (FRC) are a type of stromal cell that form the three-dimensional structure networks of the T cell-rich zones in LNs, providing guidance paths for immigrating T lymphocytes. FRCs imprint immune responses by supporting LN architecture, recruiting immune cells, coordinating immune cell crosstalk, and presenting antigens. During inflammation, FRCs exert both spatial and molecular regulation on immune cells through their topological and secretory responses, thereby steering immune responses. Here, we propose a model in which FRCs regulate immune responses through a three-part scheme: setting up, supporting, or suppressing immune responses. FRCs engage in bidirectional interactions that enhance T cell biological efficiency. In addition, FRCs have profound effects on the innate immune response through phagocytosis. Thus, FRCs in LNs act as gatekeepers of immune responses. Overall, this study aims to highlight the emerging roles of FRCs in controlling both innate and adaptive immunity. This collaborative feedback loop mediated by FRCs may help maintain tissue function during inflammatory responses.