• Title/Summary/Keyword: Thickness Effect

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Therapeutic Effects of LED Fusion of Two Wavelength Bands on Atopic Dermatitis of NC/Nga Mice (융합 LED 광선치료가 아토피 피부염에 미치는 영향)

  • Lee, Sangmin;Choi, Ji-Hye;Koo, Bon-Jun;Kwon, Jungkee
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.4
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    • pp.552-559
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    • 2022
  • Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching, mainly before five. The aim of this study is to investigate the effects of 405 nm+850 nm LED light therapy on AD-like symptoms in NC/Nga mice. The mice were randomly placed in the normal (Vehicle), atopic dermatitis-induced (CON), and 405 nm + 850 nm LED light therapy (LED) groups. The LED experimental group conducted 405 nm+850 nm wavelength LED ray therapy for 10 minutes a day for seven days. LED light therapy research confirmed the improvement and improvement of Dermatics score and observed the reduction of epidermal tissue thickness caused by dermatitis. Based on the significant decrease of serum IL-1𝛽 and transdermal moisture loss and serum IgE concentration due to LED light therapy, LED light therapy can help restore normal skin conditions in mice that cause atopic dermatitis. This study showed the anti-atopic effect of infrared light and blue light. Light in mice with atopic dermatitis led to the simultaneous use of circular LEDs with two wavelengths.

Delamination Prediction of Semiconductor Packages through Finite Element Analysis Reflecting Moisture Absorption and Desorption according to the Temperature and Relative Humidity (유한요소 해석을 통해 온도와 상대습도에 따른 수분 흡습 및 탈습을 반영한 반도체 패키지 구조의 박리 예측)

  • Um, Hui-Jin;Hwang, Yeon-Taek;Kim, Hak-sung
    • Journal of the Microelectronics and Packaging Society
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    • v.29 no.3
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    • pp.37-42
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    • 2022
  • Recently, the semiconductor package structures are becoming thinner and more complex. As the thickness decrease, interfacial delamination due to material mismatch can be further maximized, so the reliability of interface is a critical issue in industry field. Especially, the polymers, which are widely used in semiconductor packaging, are significantly affected by the temperature and moisture. Therefore, in this study, the delamination prediction at the interface of package structure was performed through finite element analysis considering the moisture absorption and desorption under the various temperature conditions. The material properties such as diffusivity and saturated moisture content were obtained from moisture absorption test. The hygro-swelling coefficients of each material were analyzed through TMA and TGA after the moisture absorption. The micro-shear test was conducted to evaluate the adhesion strength of each interface at various temperatures considering the moisture effect. The finite element analysis of interfacial delamination was performed that considers both deformation due to temperature and moisture absorption. Consequently, the interfacial delamination was successfully predicted in consideration of the in-situ moisture desorption and temperature behavior during the reflow process.

Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways

  • Xu, Chang;Li, Liangchang;Wang, Chongyang;Jiang, Jingzhi;Li, Li;Zhu, Lianhua;Jin, Shan;Jin, Zhehu;Lee, Jung Joon;Li, Guanhao;Yan, Guanghai
    • Journal of Ginseng Research
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    • v.46 no.4
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    • pp.550-560
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    • 2022
  • Background: The effect of ginsenoside Rh2 (G-Rh2) on mast cell-mediated anaphylaxis remains unclear. Herein, we investigated the effects of G-Rh2 on OVA-induced asthmatic mice and on mast cell-mediated anaphylaxis. Methods: Asthma model was established for evaluating airway changes and ear allergy. RPMCs and RBL-2H3 were used for in vitro experiments. Calcium uptake, histamine release and degranulation were detected. ELISA and Western blot measured cytokine and protein levels, respectively. Results: G-Rh2 inhibited OVA-induced airway remodeling, the production of TNF-α, IL-4, IL-8, IL-1β and the degranulation of mast cells of asthmatic mice. G-Rh2 inhibited the activation of Syk and Lyn in lung tissue of OVA-induced asthmatic mice. G-Rh2 inhibited serum IgE production in OVA induced asthmatic mice. Furthermore, G-Rh2 reduced the ear allergy in IgE-sensitized mice. G-Rh2 decreased the ear thickness. In vitro experiments G-Rh2 significantly reduced calcium uptake and inhibited histamine release and degranulation in RPMCs. In addition, G-Rh2 reduced the production of IL-1β, TNF-α, IL-8, and IL-4 in IgE-sensitized RBL-2H3 cells. Interestingly, G-Rh2 was involved in the FcεRI pathway activation of mast cells and the transduction of the Lyn/Syk signaling pathway. G-Rh2 inhibited PI3K activity in a dose-dependent manner. By blocking the antigen-induced phosphorylation of Lyn, Syk, LAT, PLCγ2, PI3K ERK1/2 and Raf-1 expression, G-Rh2 inhibited the NF-κB, AKT-Nrf2, and p38MAPK-Nrf2 pathways. However, G-Rh2 up-regulated Keap-1 expression. Meanwhile, G-Rh2 reduced the levels of p-AKT, p38MAPK and Nrf2 in RBL-2H3 sensitized IgE cells and inhibited NF-κB signaling pathway activation by activating the AKT-Nrf2 and p38MAPK-Nrf2 pathways. Conclusion: G-Rh2 inhibits mast cell-induced allergic inflammation, which might be mediated by the AKT-Nrf2/NF-kB and p38MAPK-Nrf2/NF-κB signaling pathways.

Effect of Zephyr Producing Method on Properties of Bamboo Zephyr Boards (대나무 Zephyr의 제조 조건에 따른 보드의 물성비교)

  • Kim, Yu-Jung;Roh, Jeang-Kwan;Park, Sang-Jin
    • Journal of the Korean Wood Science and Technology
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    • v.31 no.4
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    • pp.24-30
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    • 2003
  • In order to develop structural 'bamboo zephyr board', properties of boards produced by various methods making zephyr were estimated. All of boards were tested with KS(Korean Standards) F 3014 Particle board, and results were summarized as follow. The zephyr boards produced by final 1.5 mm roller space had the best properties(MOR, MOE and IB strength) among boards produced by different final roller space. Also, they had the best properties(MOR and MOE) in bending test after 1 hour soaking treatment after 2 hour-boiling in water, which were similar to properties of boards in dry-condition. Thickness swelling(TS) of all boards was less than 12% required to the Korean Standards A 3014. Zephyr boards produced by final 1.5 mm roller space also had the lowest values among all of boards. Boards produced by non-treatment (in green condition) had the better strength than those of boards produced by different pre-treatment methods(boiling in water and in 0.3% NaOH) in bending test.

A Study on the Method of Evaluating Optical-system Performance and an Athermal Structure through Thermal Analysis of the Korsch Telescope (Korsch 망원경의 열분석을 통한 광학계 성능 평가 방법 및 비열화 구조 연구)

  • Kim, Kyu-Ho;Park, Seong-Woo;Park, Seung-Han;Lee, Kyoung-Mook;Jung, Mee-Suk
    • Korean Journal of Optics and Photonics
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    • v.32 no.6
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    • pp.266-275
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    • 2021
  • In this paper, a method for evaluating optical-system performance and an athermal structure through thermal analysis of the Korsch telescope was studied. In the case of an optical system having a complex asymmetrical structure, there is a limit to implementing the satellite structure by applying the coefficient of thermal expansion (CTE) in the optical-design software, so it is difficult to evaluate the performance of the optical system against temperature changes. To solve this problem, using mechanical design software all length changes were implemented in all structures that affect the optical system according to temperature, and the value of the change in distance between optical components due to temperature change was organized. Also, the values of changes in shape and thickness of the optical components against temperature changes are organized in the optical-design software. All changes derived from both software packages were applied in the optical software to evaluate the performance of the optical system. As a result, it was found that the MTF for a spatial resolution of 71.4 cycles/mm was maintained at more than 25% in the range from 9 ℃ to 33 ℃. In addition, the performance of the optical system applying the improved structure was evaluated, by finding the structure that had the most influence on the optical system's performance change, and deriving an athermal structure to reduce the effect. As a result, it was found that the MTF for a resolution of 71.4 cycles/mm was maintained at over 67% in the range from 9 ℃ to 33 ℃.

Evaluation on the Performance of Relief Wells Using Geosynthetics Blanket Length as a Parameter in an Agricultural Reservoir Embankment (농업용 저수지 제방에서 토목섬유 블랭킷의 길이에 따른 감압정의 성능 평가)

  • Ryu, Jeonyong;Kim, Seungwook;Chang, Yongchai
    • Journal of the Korean GEO-environmental Society
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    • v.23 no.6
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    • pp.5-17
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    • 2022
  • The performance of the relief wells installed for the purpose of controlling seepage of the dam embankment is affected by various parameters such as diameter, spacing, penetration rate, permeability coefficient of the ground, thickness of the foundation layer. Therefore, when the relief wells are adopted for the purpose of reducing seepage pressure, these parameters should be sufficiently reviewed to determine the installation specifications of the relief wells. This study evaluated the effect of the length of the geosynthetics blanket on the performance of the relief wells installed in the downstream part of the dam embankment with blankets in the upstream and downstream part of the dam embankment as countermeasure methods to control seepage of the dam embankment. In the relationship between the length of the upstream and downstream blanket and the discharge, the discharge of the relief wells decreases as the length of the upstream blanket increases, and on the other hand, the discharge of the relief wells decreases as the length of the downstream blanket increases. In the upper and lower blanket length-spacing relationship, as the length of the upstream blanket increases, the spacing of the relief wells increases and as the length of the downstream blanket increases, the spacing of the relief wells decreases. Therefore, when installing the relief wells in parallel with the blanket, it was found that increasing the length of the upstream blanket is more efficient than increasing the length of the downstream blanket in order to minimize the discharge of seepage discharge and to ensure economic feasibility by wider installation of the relief wells.

Effect of γ-Aminobutyric Acid and Probiotics on the Egg Quality, Blood Parameter, Stress Level in Broiler Breeder (γ-Aminobutyric Acid 및 생균제 급여가 여름철 육용 종계의 계란 품질 및 혈액 성상에 미치는 영향)

  • Yoo Don, Ko;Ji Heon, Kim;Ha Guyn, Sung
    • Korean Journal of Poultry Science
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    • v.49 no.4
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    • pp.247-253
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    • 2022
  • This study was conducted to investigate the effects of γ-aminobutyric acid (GABA) and a probiotic mixture on egg quality, blood parameters, and corticosterone content in broiler breeder stock in summer in Korea. A total of 72 broiler breeders (Arbor Acres) at 49 weeks old were randomly divided into the following three groups of 24 heads each: control, GABA, and probiotics (1 × 108/g Bacillus licheniformis, 1 × 107/g Lactiplantibacillus plantaru, and 1 × 107/g Clostridium butyricum). The hens were fed a diet containing 50 mg of GABA/kg of feed and 0.1% probiotics for 6 weeks. Egg quality, blood parameters, and stress levels (corticosterone concentration) of the broiler breeders were evaluated. No significant differences were observed in the egg weight, albumen height, Haugh units, yolk color, shell thickness, or shell strength between the groups. There were no significant between-group differences in the blood biochemical profile, including total cholesterol, triglyceride, glucose, total protein, aspartate aminotransferase, alanine aminotransferase, albumin, and inorganic phosphorus concentrations. The corticosterone concentration was significantly lower in the GABA and probiotics groups than the control group (P < 0.05) at 6 weeks of age. In conclusion, these results suggest that dietary probiotics and GABA significantly improve the stress levels of broiler breeders in summer in Korea.

Electrical and Optical Properties of ITO Thin Films with Various Thicknesses of SiO2 Buffer Layer for Capacitive Touch Screen Panel (정전용량식 터치스크린 패널을 위한 SiO2 버퍼층 두께에 따른 ITO 박막의 전기적 및 광학적 특성)

  • Yeun-Gun, Chung;Yang-Hee, Joung;Seong-Jun, Kang
    • The Journal of the Korea institute of electronic communication sciences
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    • v.17 no.6
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    • pp.1069-1074
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    • 2022
  • In this study, we prepared ITO thin films on the Nb2O5/SiO2 double buffer layer and investigated electrical and optical properties according to the change of SiO2 buffer layer thickness (40~50nm). The ITO thin film fabricated on the Nb2O5/SiO2 double buffer layer exhibited a broad surface roughness with a small value ranging of 0.815 to 1.181nm, and the sheet resistance was 99.3 to 134.0Ω/sq. It seems that there is no problem in applying the ITO thin film to a capacitive touch screen panel. In particular, the average transmittance in the short-wavelength (400~500nm) region and the chromaticity (b*) of the ITO thin film deposited on the Nb2O5(10nm)/SiO2(40nm) double buffer layer showed significantly improved results as 83.58% and 0.05, respectively, compared to 74.46% and 4.28 of ITO thin film without double buffer layer. As a result, it was confirmed that optical properties such as transmittance in the short-wavelength region and chromaticity were remarkably improved due to the index matching effect in the ITO thin film with the Nb2O5/SiO2 double buffer layer.

Effects of the Daylight Disturbance on the Growth and Yield of Cut Flower Rose 'Monet' (Rosa hybrida cv. 'Monet') (일조방해가 절화 장미의 생육 및 수량에 미치는 영향)

  • Yuri, Lee;Sang Kun, Park
    • Journal of Practical Agriculture & Fisheries Research
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    • v.24 no.4
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    • pp.30-34
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    • 2022
  • This study was carried out to analyze the effect of changes in the light environment caused by the daylight disturbance on the productivity and quality of the standard cut flower rose cultivar 'Monet'. It was artificially shaded to obstruct the sunlight and the productivity and growing characteristics of roses according to the time of daylight disturbance were investigated. The number of cut flowers per unit area (3.3m2) of the cut flower rose 'Monet' was 40 stems in the control, while in the 4-hour, 8-hour, and 12-hour treatments, it was 32, 29, and 25, respectively. As the daylight disturbance time was increased, the number of cut flowers showed a tendency to decrease. In the case of cut flower characteristics related to the quality of cut roses, all characteristics such as flower width, flower height, petal length, and petal width, decreased by 10 to 20% in the 12-hour treatment compared to the control. In addition, growth characteristics such as peduncle length, peduncle thickness, and cut flower height, which determine the marketability of cut roses, also tended to decrease as the daylight disturbance time increased. On the other hand, the number of days to flowering increased by 14.0% from 24.3 to 27.7. The overall growth characteristics were contracted and flowering was delayed as the time of daylight disturbance increased. In the results of this study, as the daylight disturbance time increased, flower size, cut flower length, and fresh weight was decreased. This is due to the decrease in the total photosynthetic amount as the daily average photosynthetic photon flux density (PPFD) was decreased, resulting in a decrease in the quality of roses. It is judged that it is because they do not receive enough carbohydrates necessary for growth and development.

Effect of γ-Aminobutyric Acid and Probiotics on the Performance, Egg Quality and Blood Parameter of Laying Hens Parent Stock in Summer (γ-Aminobutyric Acid 및 생균제 급여가 여름철 산란 종계의 생산성, 계란 품질 및 혈액 성상에 미치는 영향)

  • Ji Heon, Kim;Yoo Don, Ko;Ha Guyn, Sung
    • Korean Journal of Poultry Science
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    • v.49 no.4
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    • pp.239-246
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    • 2022
  • This study was conducted to investigate the effects of dietary γ-aminobutyric acid (GABA) and a probiotic mixture on egg production and quality, blood parameters, and stress levels (corticosterone) in Hy-Line parent stock during summer in Korea. A total of 105 Hy-Line parent stock aged 24 weeks were randomly divided into three groups, each containing thirty-five birds: control, γ-aminobutyric acid (GABA), and probiotics (1 × 108/g Bacillus licheniformis, 1 × 107/g Lactobacillus plantarum, and 1 × 107/g Corynebacterium butyricum). The hens were fed a diet containing 50 ppm GABA or 0.1% probiotics for 6 weeks. Compared with the control group, the hen-day egg production, egg mass, and feed conversion ratio over the total period were significantly higher in the probiotic group (P<0.05). In contrast no significant differences were detected among groups with respect to egg weight, albumen height, Haugh units, yolk color, shell thickness or shell strength. Similarly, no significant difference were observed among groups with regards to biochemical profile (total cholesterol, triglyceride, glucose, total protein, aspartate aminotransferase, alanine aminotransferase, albumin, and inorganic phosphorus). However, compared with the control group, we did detect significant reductions in corticosterone levels in the GABA and probiotics groups (P<0.05). On the basis of our findings in this study, it would appear that dietary GABA and probiotics can alleviate heat stress in Hy-Line parent stock, with probiotics in particular being found to promote significant improvements in the hen-day egg production, egg mass, and feed conversion of laying hens during the summer season in Korea.