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http://dx.doi.org/10.12925/jkocs.2022.39.4.552

Therapeutic Effects of LED Fusion of Two Wavelength Bands on Atopic Dermatitis of NC/Nga Mice  

Lee, Sangmin (Department of Laboratory Aniaml Medicine, College of Veterinary Medicine, Jeonbuk National University)
Choi, Ji-Hye (Department of Laboratory Aniaml Medicine, College of Veterinary Medicine, Jeonbuk National University)
Koo, Bon-Jun (Zero 9 material Co. LTD.)
Kwon, Jungkee (Department of Laboratory Aniaml Medicine, College of Veterinary Medicine, Jeonbuk National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.39, no.4, 2022 , pp. 552-559 More about this Journal
Abstract
Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching, mainly before five. The aim of this study is to investigate the effects of 405 nm+850 nm LED light therapy on AD-like symptoms in NC/Nga mice. The mice were randomly placed in the normal (Vehicle), atopic dermatitis-induced (CON), and 405 nm + 850 nm LED light therapy (LED) groups. The LED experimental group conducted 405 nm+850 nm wavelength LED ray therapy for 10 minutes a day for seven days. LED light therapy research confirmed the improvement and improvement of Dermatics score and observed the reduction of epidermal tissue thickness caused by dermatitis. Based on the significant decrease of serum IL-1𝛽 and transdermal moisture loss and serum IgE concentration due to LED light therapy, LED light therapy can help restore normal skin conditions in mice that cause atopic dermatitis. This study showed the anti-atopic effect of infrared light and blue light. Light in mice with atopic dermatitis led to the simultaneous use of circular LEDs with two wavelengths.
Keywords
Atopic dermatitis; Light therapy; LED; Fusion; NC/Nga mouse;
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