• Journal of Veterinary Clinics
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• v.21 no.4
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• pp.336-342
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• 2004

The immunoenhancing effect of CLA isomers (CLA mixture, 10t-12c CLA, 9c-11c CLA, 9c-11c CLA, and 9t-11t CLA) on phagocytic activity of porcine peripheral blood leukocytes was examined. The phagocytic activities of peripheral blood mononuclear cells (PBMC) and polymorphonuclear cells (PMN) were analyzed by a flow cytometry system. The direct treatments of CLA isomers have no effect on phagocytosis of PMN as well as PBMC composed of approximately 10% monocytes and 90% lymphocytes. However, the phagocytic activities of PMN and monocyterich fraction from PBMC were remarkably enhanced by culture supernatant from PBMC treated with CLA mixture, 10t-12c CLA and 9c-11t CLA but not 9c-11c CLA and 9t-11t CLA. The phagocytic activity of PBMC was not enhanced by culture supernatant from PBMC treated with all CLA isomers. These results indicated that CLA isomers such as CLA mixture, l0t -12c CLA and 9c-11t CLA have an enhancing effect on phagocytosis of PMN and monocytes, which may be mediated through active humoral substances produced by CLA-stimulated PBMC. This study suggested that CLA stimulates PBMC to elaborate soluble factor(s), which may be an important mechanism for the enhancement of phagocytosis in non-specific immunity.

• Communications of the Korean Mathematical Society
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• v.12 no.2
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• pp.275-285
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• 1997

Let E be a uniformly convex Banach space with a uniformly G$\hat{a}teaux differentiable norm, C a nonempty closed convex subset of $E, T : C \to E$ a nonexpansive mapping, and Q a sunny nonexpansive retraction of E onto C. For $u \in C$ and $t \in (0,1)$, let $x_t$ be a unique fixed point of a contraction $R_t : C \to C$, defined by $R_tx = Q(tTx + (1-t)u), x \in C$. It is proved that if ${x_t}$ is bounded, then the strong $lim_{t\to1}x_t$ exists and belongs to the fixed point set of T. Furthermore, the strong convergence of ${x_t}$ in a reflexive and strictly convex Banach space with a uniformly G$\hat{a}$teaux differentiable norm is also given in case that the fixed point set of T is nonempty.

• Korean Journal of Mathematics
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• v.29 no.1
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• pp.25-40
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• 2021

In this article we introduce tribonacci sequence spaces c0(T) and c(T) derived by the domain of a newly defined regular tribonacci matrix T. We give some topological properties, inclusion relations, obtain the Schauder basis and determine ��-, ��- and ��- duals of the spaces c0(T) and c(T). We characterize certain matrix classes (c0(T), Y) and (c(T), Y), where Y is any of the spaces c0, c or ℓ∞. Finally, using Hausdorff measure of non-compactness we characterize certain class of compact operators on the space c0(T).

• Journal of the Korean Applied Science and Technology
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• v.31 no.2
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• pp.255-264
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• 2014

This study was performed to elucidate the biochemical mechanism of metabolism on reducing blood lipid, by oral administration of egg yolk in rats. A total of 36 Sprague Dawley male rats were randomized into four treatment groups, according to a randomized block design. Each group was further divided into three repeat cages, with each repeat cage comprising of 3 rats. The animals were orally administered with egg yolk once a day, while feeding the same purified pellet diet for 6 weeks. The four treatment groups were: C(control, saline 1.0 g), T1(pork belly oil 1.0 g), T2(egg yolk 1.0 g), T3(pork belly oil 1.0 g and egg yolk 1.0 g alternating every week). The measured parameters in each group are listed as follows in the order of highest to the lowest: daily average gain of body weight(T1>T3>T2>C); blood triglyceride and total cholesterol(T1>C>T3>T2) HDL-C (T2>C>T3>T1); and LDL-C (T1>T3>C>T2). AST and ALT, which are the index of liver function, were the highest in T1 but was lowest in T2. The weights of the liver, spleen, and kidney, except for the abdominal fat, showed no significant difference. The weight of abdominal fat was the highest in T1, but there were no significant difference among C, T2, and T3. The HMG-CoA reductase activity was the highest in T1 followed by T3, C but T2 was lowest. The daily fecal excretions of the total sterol, neutral sterol and acid sterol was highest in T2 but lowest in T1. The results of this study show that the egg consumption reduces the blood lipid through facilitation of fecal excretions of sterols and inhibition of enzyme activity in cholesterol biosynthesis, in the liver of animal and human.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.3 s.174
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• pp.676-684
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• 2000

In this study, behavior of $C_t$ which is a well-known fracture parameter characterizing creep crack growth rate, is investigated for weld interface cracks. Finite element analyses were per formed for a C(T) specimen under constant loading condition for elastic-plastic-creeping materials. In modeling C(T) geometry, an interface was employed along the crack plane which simulated the interface between weld and base metals. The $C_t$ versus time relations were obtained under various creep constant combinations and plastic constant combinations for weld and base metals, respectively. A unified $C_t$ versus time curve is obtained by normalizing $C_t$ with $C^*$ and t with $t_T$ for all the cases of material constant variations.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.9
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• pp.949-956
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• 2009

The C(t)-integral describes amplitude of stress and strain rate field near a tip of stationary crack under transient creep condition. Thus the C(t)-integral is a key parameter for the high-temperature crack assessment. Estimation formulae for C(t)-integral of the cracked component operating under mechanical load alone have been provided for decades. However, high temperature structures usually work under combined mechanical and thermal load. And no investigation has provided quantitative estimates for the C(t)-integral under combined mechanical and thermal load. In this study, 3-dimensional finite element analyses were conducted to calculate the C(t)-integral of elastic-creep material under combined mechanical and thermal load. As a result, redistribution time for the crack under combined mechanical and thermal load is re-defined through FE analyses to quantify the C(t)-integral. Estimates of C(t)-integral using this proposed redistribution time agree well with FE analyses results.

• Journal of Aquaculture
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• v.10 no.3
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• pp.357-362
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• 1997

In order to obtain the basic information for seedling production of flatfish, Limanda herzensteini, the influence of water temperature and salinity on egg development was investigated. The desirable water temperature for egg hatching was9~$15^\circC$. The time of egg development was shorter with higher water temperature. The relationships between the water temperature (T:$^\circC$) and the required time (t:hour) from egg to each development stage were given as follows ; 8-cell : 1/t=0.0284T-0.0554 (r=0.9999) Morula : 1/t=0.0137T-0.0527 (r=0.9998) Kupffer's vesicle : 1/t=0.0035T-0.0133 (r=0.9762) Hatching : 1/t=0.0012T-0.0007 (r=0.9981) Biological mimimum temperature for the egg development was estimated to the be $2.6^\circC$ in average. The salinity which showed over 50% survival rate from fertilized egg to hatching was 35~$38\textperthousand$.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.7
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• pp.759-768
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• 2012

This paper proposes a method to determine the elastic follow-up factors for the $C(t)$-integral under secondary stress. The rate of creep crack growth for transient creep is correlated with the $C(t)$-integral. Elastic follow-up behavior, which occurs in structures under secondary loading, prevents a relaxation of stress during transient creep. Thus, both the values of $C(t)$ and creep crack growth increase as increasing elastic follow-up. An estimation solution for $C(t)$ was proposed by Ainsworth and Dean based on the reference stress method. To predict the value of $C(t)$ using this solution, an independent method to determine the elastic follow-up factors for cracked bodies is needed. This paper proposed that the elastic follow-up factors for $C(t)$ can be determined by elastic-plastic analyses using the plastic-creep analogy. Finite element analyses were performed to verify this method.

• Animal Systematics, Evolution and Diversity
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• v.9 no.2
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• pp.151-170
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• 1993

Morphometric, band-pattern and electrophoretic analysis on Cobitis taenia complex were performed to investigate the morphological and genetic differentiation and to clarify their taxonomic status. Intermediate types of band-pattern (C and D type) were more frequently expressed than that of types of C. t. taenia(type A) and C. t. lutheri (type B). Sexual dimorphism of band-pattern was observed not only in C. t. taenia(type A) and C. t. lutheri(type B). Sexual dimorphism of band-pattern was observed not only in C. t. lutheri but also in C. t. taenia and C. t. striata as well. Discriminant function analysis based on 19 morphological characters shows no significant differences among C. taenia complex. The degree of genic variation of C. t. striata was higher ( =1.48, P=31.2%, HD=0.009) than those of C. t. striata was higher( =1.48, P=31.2%, HD=0.082 and HG=0.009) than those of C. t. lutheri ( =1.37, P=2.7%, HD=0.058 and HG=0.065). The average genetic similarities between C. t. lutheri and C. t. taenia-C. t. striata were S=0.62 and S=0.66 respectively and these values indicate that C. t. tanenia has evolved specific level of differentiation. C. t. striata and C. t. lutheri show subspecifc level of close genetic similarity (S=0.82). Based on the divergent time estimate (Nei, 1975) it is assumed that C. t. tanenia was branched off from the other subspecies about two million years before present (MYBP) and C. t. striata and C. t. lutheri were differentiated about 0.6 MYBP. The use of C. sinesis an the scientific name for the Korean C. t. taenia, proposed by Kim and Lee (1988) seems incorrect since they are quite different in the structure of lamina circularis (Vladycov, 1935), the external morphology and distribution (Cheng and Zheng, 1987) and the chromosome number(Yu et al., 1989). Kim and Lee(1988) also argued that C.t. striata and C. t. lutheri should be treated as distinct species but the present study and other reports (Kim and Lee, 1984; Kim and Yang, 1993) do not support it. We conclude that C. t. taenia is a good species and C. t. striata and C. t. lutheri are subspecific status. Their scientific names should be revised in the future.

• Journal of Nutrition and Health
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• v.37 no.7
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• pp.533-539
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• 2004

It has been reported that CLA decreases fat deposition in vivo and in vitro experiments. Among CLA isomers, c9t11 and t10c12 have been shown to exert active biological activities. For example, t10c12 reduces body weight and increases lean body mass, whereas, c9t11 has little effect on body fattness. However, the underlying molecular mechanism for the anti-obesity action of CLA isomers are not well understood. The purpose of this study was to examine the effects of t10c12 and c9t11 on lipid accumulation, cell proliferation, cell death and the expression levels of Ucp genes which are proposed as targets for anti-obesity in 3T3-L1 preadipocytes. Isomers of CLA at 50$\mu$M were added into preadipocyte differentiation medium for 3, 6 and 9days. Control cells received only the vehicle in the differentiation medium. Cytochemical analyses for lipid accumulation, cell proliferation and apotosis were carried out to compare lipidogenesis and cellular activity. RT-PCR analysis of GAPDH, Ucp 2,3 and 4 were also performed to find any modulatory effects of CLA isomers on the metabolic genes. Lipid accumulation indicated by Oil Red-O staining was inhibited in CLA isomers as compared to the control. T10c12 isomer showed less lipidogenesis than c9t11 did. A decrease occurred in CLA isomers as shown by BrdU incorporation. Apotosis has occured at higher level in t10c12 when compared to that of t9c11. Ucp 2, 3 and 4 genes were also upregulated in CLA isomers. T10c12 showed higher level of Ucp gene expressions than the c9t11 did. The biological activities of CLA isomers were also found to be different during differentiation of 3T3-L1 preadipocytes, suggesting that different isomers may be active in certain stage of lipidogenesis. The results indicate that both c9t11 and t10c12 CLA isomers decrease lipidogenesis, inhibit cell proliferation, increase cell death and upregulate in Ucp gene expressions during 3T3-L1 preadipocyte differentiation. T10c12 isomer was more effective than c9t11 in overall anti-obesity activity.