• The korean journal of orthodontics
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• v.38 no.4
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• pp.228-239
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• 2008

Objective: The aim of this study was to evaluate the strain induced in the cortical bone surrounding an orthodontic microimplant during insertion. Methods: A 3D finite element method was used to model the insertion of a microimplant (AbsoAnchor SH1312-7, Dentos Co., Daegu, Korea) Into 1 mm thick cortical bone with a pre-drilled hole of 0.9 mm in diameter. A total of 1,800 analysis steps was used to simulate the 10 turns and 5 mm advancement of the microimplant. A series of remesh in the cortical bone was allowed to accommodate the change in the geometry accompanied by the implant insertion. Results: Bone strains of well higher than 4,000 microstrain, the reported upper limit for normal bone remodeling, was observed in the bone along the whole length of the microimplant. At the bone in the vicinity of the screw tip, strains of higher than 100% was recorded. The insertion torque was calculated at approximately 1.2 Ncm which was slightly lower than those measured from the animal experiment using rabbit tibias. Conclusions: The insertion process of a microimplant was successfully simulated using the 3D finite element method which showed that bone strains from a microimplant insertion might have a negative impact on physiological remodeling of bone.

• The Journal of Advanced Prosthodontics
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• v.6 no.2
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• pp.103-108
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• 2014

PURPOSE. The occlusal splint has been used for many years as an effective treatment of sleep bruxism. Several methods have been used to evaluate efficiency of the occlusal splints. However, the effect of the occlusal splints on occlusal force has not been clarified sufficiently. The purpose of this study was to evaluate the effect of occlusal splints on maximum occlusal force in patients with sleep bruxism and compare two type of splints that are Bruxogard-soft splint and canine protected hard stabilization splint. MATERIALS AND METHODS. Twelve students with sleep bruxism were participated in the present study. All participants used two different occlusal splints during sleep for 6 weeks. Maximum occlusal force was measured with two miniature strain-gage transducers before, 3 and 6 weeks after insertion of occlusal splints. Clinical examination of temporomandibular disorders was performed for all individuals according to the Craniomandibular Index (CMI) before and 6 weeks after the insertion of splints. The changes in mean occlusal force before, 3 and 6 weeks after insertion of both splints were analysed with paired sample t-test. The Wilcoxon test was used for the comparison of the CMI values before and 6 weeks after the insertion of splints. RESULTS. Participants using stabilization splints showed no statistically significant changes in occlusal force before, 3, and 6 weeks after insertion of splint (P>.05) and participants using Bruxogard-soft splint had statistically significant decreased occlusal force 6 weeks after insertion of splint (P<.05). There was statistically significant improvement in the CMI value of the participants in both of the splint groups (P<.05). CONCLUSION. Participants who used Bruxogard-soft splint showed decreases in occlusal force 6 weeks after insertion of splint. The use of both splints led to a significant reduction in the clinical symptoms.

• The korean journal of orthodontics
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• v.39 no.4
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• pp.203-212
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• 2009

Objective: The aim of this study was to evaluate the strain induced in the cortical bone surrounding an orthodontic microimplant during insertion in a self-drilling manner. Methods: A 3D finite element method was used to simulate the insertion of a microimplant (AbsoAnchor SH1312-7, Dentos Co., Daegu, Korea) into 1 mm thick cortical bone. The shape and dimension of thread groove in the center of the cortical bone produced by the cutting flute at the apical of the microimplant was obtained from animal test using rabbit tibias. A total of 3,600 analysis steps was used to calculate the 10 turns and 5 mm advancement of the microimplant. A series of remesh in the cortical bone was allowed to accommodate the change in the geometry accompanied by the implant insertion. Results: Bone strains of well higher than 4,000 microstrain, the reported upper limit for normal bone remodeling, were observed in the peri-implant bone along the whole length of the microimplant. Level of strains in the vicinity of either the screw tip or the valley part were similar. Conclusions: Bone strains from a microimplant insertion in a self-drilling manner might have a negative impact on the physiological remodeling of cortical bone.

• Journal of Life Science
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• v.7 no.1
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• pp.49-58
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• 1997

Single P[en-lacZ] element including 5.7 kb of engrailed upstream sequences and the E. coli lacZ fusion gene, localized on 48A in rxyho25 strain was transposed to different sites in the Drosophila genome by the jumpstart technique. From 3315 individual genetic crosses, 113 new insertion lines carrying P[en-lacZ] inserted at different sites were obtained. $\beta$-Galactosidase expression in larval tissues of 113 insertion lines were detected by X-gal staining. & among 113 lines have been indentified to be for recessive lethal mutations. Among 7 lines, the #1119 line being lethal during embryogenesis was examined about the ${\beta}$$-Galactosidase expression, nuclear behavior and cellularization pattern during embryogenesis. The P[en-lacZ] insertion lines obtained in this study could be utilized for studying structure and function of the Drosophila development-related genes.

• Journal of Microbiology and Biotechnology
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• v.17 no.8
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• pp.1344-1352
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• 2007

An opportunistic human pathogen, Pseudomonas aeruginosa, contains the major catalase KatA, which is required to cope with oxidative and osmotic stresses. As an attempt to uncover the $H_2O_2$-dependent regulatory mechanism delineating katA gene expression, four prototrophic $H_2O_2$-sensitive mutants were isolated from about 1,500 TnphoA mutant clones of P. aeruginosa strain PA14. Arbitrary PCR and direct cloning of the transposon insertion sites revealed that one insertion is located within the katA coding region and two are within the coding region of oxyR, which is responsible for transcriptional activation of several antioxidant enzyme genes in response to oxidative challenges. The fourth insertion was within PA3815 (IscR), which encodes a homolog of the Escherichia coli iron-sulfur assembly regulator, IscR. The levels of catalase and SOD activities were significantly reduced in the iscR mutant, but not in the oxyR mutant, during the normal planktonic culture conditions. These results suggest that both IscR and OxyR are required for the optimal resistance to $H_2O_2$, which involves the expression of multiple antioxidant enzymes including KatA.

• The korean journal of orthodontics
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• v.41 no.1
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• pp.25-35
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• 2011

Objective: The purpose of this study was to optimize the thread pattern of orthodontic microimplants. Methods: In search of an optimal thread for orthodontic microimplants, an objective function stability quotient (SQ) was built and solved which will help increase the stability and torsional strength of microimplants while reducing the bone damage during insertion. Selecting the AbsoAnchor SH1312-7 microimplant (Dentos Inc., Daegu, Korea) as a control, and using the thread height (h) and pitch (p) as design parameters, new thread designs with optimal combination of hand p combination were developed. Design soundness of the new threads were examined through insertion strain analyses using 3D finite element simulation, torque test, and clinical test. Results: Solving the function SQ, four new models with optimized thread designs were developed (h200p6, h225p7, h250p8, and h275p8). Finite element analysis has shown that these new designs may cause less bone damage during insertion. The torsional strength of two models h200p6 and h225p7 were significantly higher than the control. On the other hand, clinical test of models h200p6 and h250p8 had similar success rates when compared to the control. Conclusion: Overall, the new thread designs exhibited better performance than the control which indicated that the optimization methodology may be a useful tool when designing orthodontic microimplant threads.

• Nuclear Engineering and Technology
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• v.56 no.2
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• pp.359-374
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• 2024

A high-fidelity numerical analysis methodology was proposed for evaluating the fuel rod cladding integrity of a Prototype Gen IV Sodium Fast Reactor (PGSFR) during normal operation and Design basis events (DBEs). The MARS-LMR code, system transient safety analysis code, was applied to analyze the DBEs. The results of the MARS-LMR code were used as boundary condition for a 3D computational fluid dynamics (CFD) analysis. The peak temperatures considering HCFs satisfied the cladding temperature limit. The temperature and pressure distributions were calculated by ANSYS CFX code, and applied to structural analysis. Structural analysis was performed using ANSYS Mechanical code. The seismic reactivity insertion SSE accident among DBEs had the highest peak cladding temperature and the maximum stress, as the value of 87 MPa. The fuel cladding had over 40 % safety margin, and the strain was below the strain limit. Deformation behavior was elucidated for providing relative coordinate data on each active fuel rod center. Bending deformation resulted in a flower shape, and bowing bundle did not interact with the duct of fuel assemblies. Fuel rod maximum expansion was generated with highest stress. Therefore, it was concluded that the fuel rod cladding of the PGSFR has sufficient structural safety margin during DBEs.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.6A
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• pp.389-398
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• 2012

In this study, structural strain responses of the jacket-type Uldolmok tidal current power plant structure under severe tidal environments were measured and analyzed using long-term measurement system during construction and also operation. It was observed that there were significant changes in strain responses at the steps of jacket lifting, block loading, pile ejection and insertion. Strains due to dead loads and tidal loads were analyzed before and after removal of a jacket leg, and it was also found that the strains due to dead load were much significantly changed after jacket leg removal. From the measurement data during operation, it was found that strain responses were fluctuated with M2 and M4 tidal periods and also relatively short period of about 10 min due to the peculiar tidal characteristics in the Uldolmok strait. Finally, the neural network-based non-parametric estimation models were investigated to build up the signal-based structural damage monitoring system.

• The Journal of Korean Academy of Prosthodontics
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• v.48 no.3
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• pp.215-223
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• 2010

Purpose: The present study was aimed to evaluate the level of cortical bone strain during the placement of an implant. The primary concern was to investigate if the extent of overloading area near the marginal bone could be affected by microthread fabricated at the cervical 1/3 of an implant. Materials and methods: Three dimensional finite element analysis was used to simulate the insertion of 3 implants. Control model was $4.1{\times}10$ mm implant (Submerged model, Dentis Co,, Daegu, Korea) equipped with a main thread only. Type I was with main thread and microthread, and Type II had similar thread pattern but was of tapered body. A PC-based finite element software (DEFORM 3D ver 5, SFTC, Columbus, OH, USA) was used to calculate a total of 3,600 steps of analysis, which simulated the whole insertion. Results: Results showed that the strain field in the marginal bone within 1 mm of the implant wall was higher than 4,000 micro-strain in the control model. The size of bone overloading was 1-1.5 mm in Type I, and greater than 2 mm in Type II implants. Conclusion: These results indicate that the marginal bone may be at the risk of resorption on receiving the implant for all 3 implant models studied. Yet, the risk was greater for Type I and Type II implants, which had microthread at the cervical 1/3.

• International Journal of Concrete Structures and Materials
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• v.9 no.3
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• pp.369-379
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• 2015

Friction in a post-tensioning system has a significant effect on the distribution of the prestressing force of tendons in prestressed concrete structures. However, attempts to derive friction coefficients using conventional electrical resistance strain gauges do not usually lead to reliable results, mainly due to the damage of sensors and lead wires during the insertion of strands into the sheath and during tensioning. In order to overcome these drawbacks of the existing measurement system, the Smart Strand was developed in this study to accurately measure the strain and prestressing force along the strand. In the Smart Strand, the core wire of a 7-wire strand is replaced with carbon fiber reinforced polymer in which the fiber Bragg grating sensors are embedded. As one of the applications of the Smart Strand, friction coefficients were evaluated using a full-scale test of a 20 m long beam. The test variables were the curvature, diameter, and filling ratio of the sheath. The analysis results showed the average wobble and curvature friction coefficients of 0.0038/m and 0.21/radian, respectively, which correspond to the middle of the range specified in ACI 318-08 in the U.S. and Structural Concrete Design Code in Korea. Also, the accuracy of the coefficients was improved by reducing the effective range specified in these codes by 27-34 %. This study shows the wide range of applicability of the developed Smart Strand system.