• Title/Summary/Keyword: Solid support

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Solvent-Free Michael Addition Between EMME and Secondary Amine under Focused Microwave Irradiation

  • Kim, Ki-Won;Lee, Hee-Jung;Jo, Jeong-Im;Kwon, Tae-Woo
    • Bulletin of the Korean Chemical Society
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    • v.31 no.5
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    • pp.1155-1158
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    • 2010
  • Microwave-assisted Michael reaction between EMME and various amines such as diphenylamine, 4-methyl-N-phenylbenzenamine, N-phenylnaphthalen-1-amine, dihexylamine, diisopropylamine, and 4-nitrobenzenamine were described. Solvent-free conditions on alumina as solid support in the presence of $K_2CO_3$ catalysts gave moderate to good yields (55 - 93%) of diethylmalonate analogues having enamine moieties under focused microwave irradiation.

Solvent Free Microwave Accelerated Synthesis of Heterocyclic Thiazolidin-4-ones as Antimicrobial and Antifungal Agents

  • Sekhar, Kondapalli Venkata Gowri Chandra;Rao, Vajja Sambasiva;Reddy, Aravalli Satish;Sunandini, Ravada;Satuluri, V S A Kumar
    • Bulletin of the Korean Chemical Society
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    • v.31 no.5
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    • pp.1219-1222
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    • 2010
  • A simple and efficient method has been developed for conversion of arenecarbaldehyde-3-methylquinoxalin-2-ylhydrazones to 3-(2-methylquinoxalin-3-yl)-2-(substitutedphenyl)thiazolidin-4-ones in good yields using microwave irradiation technique on silica as solid support under solvent free conditions. The synthesized compounds were characterized by elemental microanalysis, infrared spectroscopy, $^1H$ NMR, and mass spectroscopy. All the synthesized thiazolidinones were investigated for their antimicrobial and antifungal activities. The results of the biological activities revealed that the compounds 3b, 3d, 3f and 3h exhibited excellent antibacterial activities while 3d and 3h exhibited good antifungal activity.

Analysis of NASA Student Launch as a NASA Managed University Rocket Competition (미국 NASA 주관 대학생 로켓 경진대회 : NASA Student Launch 사례 분석)

  • Lee, Hoon-Hee;Yoon, Yong-Sik;Min, Kyung-Ju
    • Aerospace Engineering and Technology
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    • v.13 no.1
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    • pp.129-141
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    • 2014
  • Since 2006, an annual rocket competition for university students in America has been held by management of NASA to support the Space Launch System. This paper describes the significance and operational aspects of NASA Student Launch, a rocket competition for university students organized by NASA Marshall Center's Academic Affairs Office, to inspire students to pursue education and careers in science, technology, engineering, or mathematics (STEM) fields, which is Furthermore, It describes briefly activities of Korean national rocket competition for university students.

Development of Boolean Operations for CAD System Kernel Supporting Non-manifold Models (비다양체 모델을 수용하는 CAD 시스템 커널을 위한 불리안 조직의 개발)

  • 김성환;이건우;김영진
    • Korean Journal of Computational Design and Engineering
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    • v.1 no.1
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    • pp.20-32
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    • 1996
  • The boundary evaluation technique for Boolean operation on non-manifold models which is regarded as the most popular and powerful method to create and modify 3-D CAD models has been developed. This technique adopted the concept of Merge and Selection in which the CSG tree for Boolean operation can be edited quickly and easily. In this method, the merged set which contains complete information about primitive models involved is created by merging primitives one by one, then the alive entities are selected following the given CSG tree. This technique can support the hybrid representation of B-rep(Boundary Representation) and CSG(Constructive Solid Geometry) tree in a unified non-manifold model data structure, and expected to be used as a basic method for many modeling problems such as data representation of form features, and the interference between them, and data representation of conceptual models in design process, etc.

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The Analysis of Tunnel Excavation using Finite Difference Method (유한 차분법을 이용한 터널 단면 해석)

  • 김동후;유건선
    • Proceedings of the Korean Geotechical Society Conference
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    • 1991.10a
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    • pp.166-178
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    • 1991
  • Using FLAC, which is an explicit finite difference code written for analysis of problems in geotechnical engineering, a particular example 2 in the Korean Geothechnical Society News has been analysed. The elastoplasticity formulation in FLAC assumes an elastic, perfectly plastic solid in plane strain which conforms to a Mohr-Coulomb yield condition. During tunnel excavations by stages, stresses and diaplacements in region around the tunnel varies according to distance from the face of tunnel and installation of tunnel supports, and soon. In this analysis, the three dimensional support effect of the rock mass during the process of excavation is simulated by using the stress distribution method, and varying the material constants of shotcrete in each stage also considered. The maximum convergency is occured at the crown of the tunnel and estimated to be about 12mm.

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Microfluidic immunoassay using superparamagnetic nanoparticles in an enhanced magnetic field gradient (강화된 자기장 구배 하에서 나노자성입자를 이용한 미세유체 기반의 면역 측정)

  • Hahn, Young-Ki;Kang, Joo-H.;Kim, Kyu-Sung;Park, Je-Kyun
    • Journal of Sensor Science and Technology
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    • v.15 no.3
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    • pp.158-163
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    • 2006
  • This paper reports a novel immunoassay method using superparamagnetic nanoparticles and an enhanced magnetic field gradient for the detection of protein in a microfluidic device. We use superparamagnetic nanoparticles as a label and fluorescent polystyrene beads as a solid support. Based on this platform, magnetic force-based microfluidic immunoassay is successfully applied to analyze the concentration of IgG as model analytes. In addition, we present ferromagnetic microstructure connected with a permanent magnet to increase magnetic flux density gradient (dB/dx, ${\sim}10^{4}$ T/m), which makes limit of detection reduced. The detection limit is reduced to about 1 pg/mL.

A Phenomenological Constitutive Model for Pseudoelastic Shape Memory Alloy (의탄성 형상기억합금에 대한 현상학적 구성모델)

  • Ho, Kwang-Soo
    • Transactions of Materials Processing
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    • v.19 no.8
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    • pp.468-473
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    • 2010
  • Shape memory alloys (SMAs) have the ability to recover their original shape upon thermo-mechanical loading even after large inelastic deformation. The unique feature is known as pseudoelasticity and shape memory effect caused by the crystalline structural transformation between two solid-state phases called austenite and martensite. To support the engineering application, a number of constitutive models, which can be formally classified into either micromechanics-based or phenomenological model, have been developed. Most of the constitutive models include a kinetic law governing the crystallographic transformation. The present work presents a one-dimensional, phenomenological constitutive model for SMAs in the context of the unified viscoplasticity theory. The proposed model does not incorporate the complex mechanisms of phase transformation. Instead, the effects induced by the transformation are depicted through the growth law for the back stress that is an internal state variable of the model.

The Laminating process for Single Substrate Flexible LCD

  • Bae, Kwang-Soo;Choi, Yoon-Seuk;Kim, Hak-Rin;Kim, Jae-Hoon
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08b
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    • pp.1125-1128
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    • 2007
  • The laminating technique for developing flexible liquid crystal display was demonstrated by using a thin UV curable polymer film and a plastic substrate with patterned polymer wall structure. We adopted the rigid wall structure to provide a solid mechanical support for the stable molecular alignment of liquid crystals (LCs) in the device. The cover film was prepared to have an ability of aligning LC molecules by patterning a micro-groove structure using the soft-lithographic process. These two substrates can be assembled tightly by the laminating and one-step UV irradiation process because of the adhesive nature of the used UV curable polymers. Proposed method can be used to fabricate the flexible LC display with simplicity and also be applicable for a cost-effective roll-to-roll process.

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Hg(0) Removal Using Se(0)-doped Montmorillonite from Selenite(IV)

  • Lee, Joo-Youp;Kim, Yong Jin
    • Bulletin of the Korean Chemical Society
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    • v.34 no.12
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    • pp.3767-3770
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    • 2013
  • Potassium methylselenite ($KSeO_2(OCH_3)$) was reduced to elemental selenium, Se(0), and then doped onto montmorillonite K 10 (MK10) clay to examine the interaction between elemental mercury (Hg(0)) vapor and Se(0) in an effort to understand the possible heterogeneous reaction of Hg(0) vapor and Se(0) solid. The clay was used as a cost-effective support material for uniform dispersion of Se(0). The Se(0)-doped MK10 showed an excellent reaction performance with Hg(0) under an inert nitrogen gas at 70 and $140^{\circ}C$ in our lab-scale fixed-bed system. However, the precursor, $KSeO_2(OCH_3)$-doped MK10 showed a negligible reaction performance with Hg(0), suggesting that the oxidation state of selenium plays a key role in the reaction of Hg(0) vapor and selenium compounds.

Optimizing Fsync Performance with Dynamic Queue Depth Adaptation

  • Park, Daejun;Kim, Min Ji;Shin, Dongkun
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.15 no.5
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    • pp.570-576
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    • 2015
  • Existing flash storage devices such as universal flash storage and solid state disk support command queuing to improve storage I/O bandwidth. Command queuing allows multiple read/write requests to be pending in a device queue. Because multi-channel and multi-way architecture of flash storage devices can handle multiple requests simultaneously, command queuing is an indispensable technique for utilizing parallel architecture. However, command queuing can be harmful to the latency of fsync system call, which is critical to application responsiveness. We propose a dynamic queue depth adaptation technique, which reduces the queue depth if user application is expected to send fsync calls. Experiments show that the proposed technique reduces the fsync latency by 79% on average compared to the original scheme.