• Korean Journal of Fisheries and Aquatic Sciences
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• v.54 no.3
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• pp.271-279
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• 2021

Ultrasound-assisted extraction (UAE) conditions, including extraction time, extraction temperature, and ethanol concentration, were optimized to increase the total flavonoid content (TFC), tyrosinase inhibitory activity (TIA), and collagenase inhibitory activity (CIA) of Spirulina platensis through central composite design (CCD). For the optimization of the three dependent variables, a quadratic regression model was derived from 17 experimental sets for the simultaneous maximization of TFC, TIA, and CIA. The predicted optimal UAE conditions were 44.0 min of extraction time, 82.8℃ of extraction temperature, and 96.0% of ethanol concentration. Under these conditions, 0.93 mg QE/g DM of TFC, 81.9% of CIA, and 92.1% of TIA were predicted. The CCD-based UAE optimization enabled an increase in TFC, CIA, and TIA, thereby confirming that the S. platensis extract can be used in the development of a cosmetic material with skin whitening and anti-wrinkle effects.

• Industry Promotion Research
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• v.9 no.2
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• pp.115-125
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• 2024

The increase in the elderly population and growing interest in skin beauty, alongside specialized scientific examination of natural substances, have led to a rise in the utilization of natural materials. This paper investigates the types of natural substances, the functionality of extracts, and extraction technologies based on the literature that utilizes natural ingredients to mitigate skin aging. To directly assess the impact of functional materials derived from natural products on skin aging mitigation, the functionality of the extracts was determined based on their ability to synthesize Procollagen and reduce MMP-1. Each natural product is categorized into plants, herbal medicines, and microalgae in the literature utilizing the above evaluation methods. This paper describes the extraction technologies for securing functional materials from each ingredient and the main outcomes, providing trends in research on extraction technologies for functional materials aimed at alleviating skin aging

• Journal of Oral Medicine and Pain
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• v.20 no.1
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• pp.117-126
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• 1995

In order to evaluate objectively the level of tension and relaxation in dental practices, the author used Biotrainer(BF-102R), one of the GSR biofeedback apparatus, to examine 119 dental outpatients on their changes of GSR due to infection, preparation, extraction and readjustment. The obtained results were as follows : 1. There were no differences in the baseline GSR between the control group and the patient groups. 2. Changes in GSR by practices were significantly larger than the baseline GSR. 3. GSR in female was larger than that in male 4. While the GSR after injection, preparation and extraction revealed lower level, the GSR after readjustment revealed higher level. 5. Most of subjects just after injection, preparation and extraction were more frequent in decrease of GSR and those just after readjustment more were frequent n increase of GSR. 6. Type 1,2(increase in skin resistance) showed greater in injection, preparation and extraction group, while type 3(decrease in skin resistance) did in readjustment group.

• Proceedings of the KIEE Conference
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• 2004.11c
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• pp.147-149
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• 2004

There are no authentic solutions in a face region extraction problem though it is an important part of pattern recognition and has diverse application fields. It is not easy to develop the facial region extraction algorithm because the facial image is very sensitive according to age, sex, and illumination. In this paper, to solve these difficulties, a fuzzy color filer based on the facial region extraction algorithm is proposed. The fuzzy color filter makes the robust facial region extraction enable by modeling the skin color. Especially, it is robust in facial region extraction with various illuminations. In addition, to identify the fuzzy color filter, a linear matrix inequality(LMI) optimization method is used. Finally, the simulation result is given to confirm the superiority of the proposed algorithm.

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.139-142
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• 2001

This paper presents a highly fast and accurate facial region extraction method by using the skin-color-reference map and motion information. First, we construct the robust skin-color-reference map and eliminate the background in image by this map. Additionally, we use the motion information for accurate and fast detection of facial region in image sequences. Then we further apply region growing in the remaining areas with the aid of proposed criteria. The simulation results show the improvement in execution time and accurate detection.

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.113-124
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• 2019

The purpose of the study was to investigate the effects of sea cucumber extract on skin as a natural cosmetics functional material. Subjective evaluation of cosmetics before and after were conducted with questionnaires regarding moisture content, sebum content, melanin index, and erythema index. Experiments were conducted on improvement efficacy using skin clinical trials and questionnaires to evaluate changes in perception of skin condition and efficiency of products. With the aim of minimizing skin irritation, the efficiency of the solvent used for extraction was an important factor, and the sea cucumber extract was harvested with efficient extraction conditions at a ratio of 1:10 of 50% ethanol. The study aimed to identify the suitability of sea cucumber extract as a functional cosmetics material to improve the moisturizing ability of skin and its effect on the skin by adding marine natural animal sea cucumber extract. Clinical studies on cosmetics skin containing sea cucumber extract, excellent skin improvement effect from all items of clinical experiment in experimental and control groups. Sea cucumber extract was proved to be a stable, non-adverse physiologically active substance against abnormal symptoms or side effects of skin reactions and skin problems. In addition, the study found excellent results that can lead to its use as a cosmetics material. This is expected to contribute to the development of various cosmetics industries.

• Journal of Korea Multimedia Society
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• v.8 no.5
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• pp.633-640
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• 2005

In this paper, we propose an adaptive face region extraction algorithm based on skin color information. It consists oi the extraction of face candidate region and projection step. In the step of face candidate region extraction, we extract the pixels which are regarded as the candidate skin color pixels by using the given range. Then, the ratio between the total pixels and the extracted pixels is calculated. According to the ratio, we adaptively decide the range of the skin color and extract face candidate region. In the projection step, we project the extracted face candidate region into vertical direction to estimate the width of the face. Then the redundant parts are efficiently removed by using the estimated face width. And the extracted face width information is used at the horizontal projection step to extract the height of the face. From the experiment results for the various images, the proposed algorithm shows more accurate results than the conventional algorithm.

• Journal of Advanced Navigation Technology
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• v.24 no.2
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• pp.148-154
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• 2020

Wrinkles are one of the main features of skin aging. Conventional image processing-based wrinkle detection is difficult to effectively cope with various skin images. In particular, Wrinkle extraction performance is significantly decreased when the wrinkles are not strong and similar to the surrounding skin. In this paper, deep learning is applied to extract wrinkles from microscopic skin images. In general, the microscope image is equipped with a wide-angle lens, so the brightness at the boundary area of the image is dark. In this paper, to solve this problem, the brightness of the skin image is estimated and corrected. In addition, We apply the structure of semantic segmentation network suitable for wrinkle extraction. The proposed method obtained an accuracy of 99.6% in test experiments on skin images collected in our laboratory.

• Food Science and Preservation
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• v.17 no.1
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• pp.91-99
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• 2010

Extraction and bleaching of citric acid- and pepsin-soluble collagens (ASC and PSC, respectively) from shark (Isurus oxyrinchus) skin and muscle were investigated. The optimal sodium hydroxide concentration for extraction was 0.3 M and the optimal treatment time for removal of foreign material was 9 h. The optimal sodium hypochlorite level for bleaching of shark skin was 0.48% (w/v), and sodium hypochlorite was a better bleaching agent than acetone, hydrogen peroxide (10%, v/v), sodium sulfite (0.48%, w/v), sodium thiosulfate (0.48%, w/v), or sodium metabisulfite (0.48%, w/v). Optimal citric acid concentration and extraction time for ASC were 0.3 M and 72 h, respectively, whereas optimal conditions for extraction of PSC were treatment with 0.1 M citric acid containing 0.1% (w/v) pepsin for 24 h. Protein contents in ASSC (acid-soluble shark skin collagen), ASMC (acid-soluble shark meat collagen), PSSC (pepsin-soluble shark skin collagen), and PSMC (pepsin-soluble shark meat collagen) were 88.66%, 83.09%, 90.33%, and 84.81% (on a dry weight basis), respectively, similar to that of commercial marine collagen (88.86%). Net collagen contents of ASSC, ASMC, PSSC, and PSMC, calculated from hydroxyproline levels, were 70.31%, 25.70%, 83.09%, and 32.94%, respectively. The yields of freeze-dried ASSC, ASMC, PSSC,and PSMC were 57.22%, 53.85%, 23.28%, and 20.61%.

• Journal of the Korean Applied Science and Technology
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• v.37 no.4
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• pp.674-681
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• 2020

The root of Codonopsis lanceolata has been used in traditional medicine. This study was conducted to confirm the comparative effect of ethanol solvent extraction (CLE) and supercritical carbon dioxide extraction (CLS) of C. lanceolata roots. CLS had higher antioxidant than CLE. For supercritical co-solvent modified carbon dioxide extraction (CLS), it were extracted at 250 bar 50℃ 150 min at a flow rate of ethyl alcohol 3 mL/min for 90min. In addition, CLS inhibited the adipocyte differentiation of 3T3-L1 cells. When treated with the extract at a concentration of 100 ㎍/mL, the Wnt/β-catenin pathway reporter luciferase activity of HEK 293-TOP cells increased approximately by 3-folds compared to that of the untreated control group. Also, the treatment by CLS (50 ㎍/mL) showed a significant increase of involucrin expression. These results indicate that supercritical carbon dioxide extract of C. lanceolatamay serve as a cosmeceutical agent for improving skin barrier function and the treatment of obesity.