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http://dx.doi.org/10.12925/jkocs.2019.36.1.113

Clinical Study on Skin Improvement Effect in Adult Women of Age 40 to 50 Using Cosmetics Containing Sea Cucumber Extract  

Kim, Yong-shin (Department of Bioengineering, Konkuk University)
Moon, Ji-sun (Department of Medical Beauty Care, Jungwon University)
Publication Information
Journal of the Korean Applied Science and Technology / v.36, no.1, 2019 , pp. 113-124 More about this Journal
Abstract
The purpose of the study was to investigate the effects of sea cucumber extract on skin as a natural cosmetics functional material. Subjective evaluation of cosmetics before and after were conducted with questionnaires regarding moisture content, sebum content, melanin index, and erythema index. Experiments were conducted on improvement efficacy using skin clinical trials and questionnaires to evaluate changes in perception of skin condition and efficiency of products. With the aim of minimizing skin irritation, the efficiency of the solvent used for extraction was an important factor, and the sea cucumber extract was harvested with efficient extraction conditions at a ratio of 1:10 of 50% ethanol. The study aimed to identify the suitability of sea cucumber extract as a functional cosmetics material to improve the moisturizing ability of skin and its effect on the skin by adding marine natural animal sea cucumber extract. Clinical studies on cosmetics skin containing sea cucumber extract, excellent skin improvement effect from all items of clinical experiment in experimental and control groups. Sea cucumber extract was proved to be a stable, non-adverse physiologically active substance against abnormal symptoms or side effects of skin reactions and skin problems. In addition, the study found excellent results that can lead to its use as a cosmetics material. This is expected to contribute to the development of various cosmetics industries.
Keywords
Sea cucumber extract; Moisture; Sebum; Melanin index; Erythema index;
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1 R. P. Vieira, C. Pedrosa, P. A. Mourao, "Extensive heterogeneity of proteoglycans bearing fucose-branched chondroitin sulfate extracted from the connective tissue of sea cucumber", Biochemistry, Vol.32, No.9, pp. 2254-2262.(1993).   DOI
2 B. Y. Young, "Method of manufacturing basic make-up nutrition cream with effect of improvement of wrinkles using sea cucumber extract", Korea Patent Office, Public patent announcement, 10-2008-0066151, (2008).
3 G. S. Lee, S. H. Park, Y. G. Kang, "Skin Whitening Effects of Stichopus japonicus extracts", J. Int. Wonkwang Cult, No.2, pp. 115-120, (2012).
4 R. P. Vieira, C. Pedrosa, P. A. Mourao, "Extensive heterogeneity of proteoglycans bearing fucose-branched chondroitin sulfate extracted from the connective tissue of sea cucumber", Biochemistry , Vol.32, No.9, pp. 2254-2262.(1993).   DOI
5 H. S. Ryu, J. H. Moon, J. S. Suh, "Chemical Compositions of Glycoprotein and Chondroitin Sulfates from Sea Cucumber(Stichopus japonicus)", J. Korean Soc. Food Sci. Nutr. Vol.26, No.1 pp. 77-80, (1997).
6 R. P. Vieira, P. A. Mourao, "Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumber", Journal of Biological Chemistry, Vol.263, No.34, pp. 18176-18183, (1988).   DOI
7 H. G. Oh, D. I. Moon, J. H. Kim, Y. R. Kang, J. W. Park, M. Young, S. H. Park, Y. G. Kang, C. H. Choe, I. S. Park, J. Kim, K. Y. Yu, E. D. Seol, O. J. Kim, H. Y. Lee, "The Effects of Sea Cucumber as an Anti-gastritis, Anti-gastric Ulcer, and Anti-Helicobater", J. Korean Soc. Food Sci. Nutr, Vol.41, No.5, pp. 605-611, (2012).   DOI
8 S. Y. Park, H. K. Lim, S. G. Park, M. J. Cho, "Quality and preference changes red sea cucumber (Stichopus japonicus) Kimchi during storage period", Journal of Applied Biological Chemistry, Vol.55, No.2, pp. 135-140, (2012),   DOI
9 S.C. Lee, J. H. Park, "Methods of making beauty soap containing sea cucumber extract and its beauty soap", Korea Patent Office, Public patent announcement, 10-1153287, (2012).
10 J. H .Sellstedt, C. J. Guinosso, A. J. Begany, S. C. Bell, M. Rosenthale, "Oxanilic acids, a new series of orally active antiallergic agents", J. Med. Chem, Vol.18, No.9, pp.926-33, (1975).   DOI
11 G. B. Scarfe, I. D. Wilson, M. A. Warne, E. Holmes, J. K. Nicholson, J. C. Lindon, "Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry", Xenobiotica, Vol.32, No.4, pp. 267-277, (2008).   DOI
12 M. O. Lee. "Stichopus japonicus Extract on the Skin Moisturizing and Inflammatory Markers", Wonkwang university, (2011).
13 D. I. Moon, "Improving effects of Sea cucumber semi-extract on the gastritis and gastric ulcer", Wonkwang University, (2012).
14 D. I. Moon, "Improving effects of Sea cucumber semi-extract on the gastritis and gastric ulcer", Wonkwang University, (2012).
15 T. Y. Kim, "Effecting of the Scalp Careon Hair Loss by using Sea Cucumber Scalp Enhancer With Sea Cucumber Extract", Konkuk University, (2015).
16 J. H. Kwon, Y. H. Choi, H. W. Chung, G. D. Lee, "The characteristics of a microwave extraction process used for saikosaponins from Bupleurum falcatum root", International journal of food science & technology, Vol.41, No.1, pp. 67-75, (2006).   DOI
17 S.C. Lee, J. H. Park, "Methods of making beauty soap containing sea cucumber extract and its beauty soap", Korea Patent Office, Public patent announcement, 10-1153287, (2012).
18 C. J. Lim, "Method for Manufacturing a mask pack using sea cucumber extract", Korea Patent Office, Public patent announcement, 10-2012-0080718.(2012).
19 B. Y. Young, "Method of manufacturing basic make-up nutrition cream with effect of improvement of wrinkles using sea cucumber extract", Korea Patent Office, Public patent announcement, 10-2008-0066151, (2008).
20 N. Y. Park, J. H. Kwon, H. K. Kim, "Optimization of extraction conditions for ethanol extracts from Chrysanthemum morifolium by response surface methodology," Korean Journal of Food Science and Technology, Vol.30, No.5, pp. 1189-1196, (1998).
21 J. Noh, Y. K. Choi, H. K. Kim, J. H. Kwon, "Pre-establishment of Microwave-Assisted Extraction Conditions for Antioxidative Extracts from Cabbage", Korean J, Foon Preserv, Vol.12, No.1, pp. 62-67, (2005).
22 M. O. Lee, "Stichopus japonicus Extract on the Skin Moisturizing and Inflammatory Markers", Wonkwang university, (2011).
23 H. Y . Shin, "Effects of sea cucumber (Apostichopus japoniaus)extracts on proliferation of human skin fibroblasts", Dong-Eui University. (2012).
24 C. W. Lee, Y. K. Kang, "Fermented Sea Cucumber Extract and Cosmetic Composition Containing same", Korea Patent Office, Public patent announcement, 10-2012-0082923, (2014).
25 Y. H. Jeung, "Study of Additives and Heating Methods for Optimal Taste and Swelling of Sea cucumber", Sejong University, (2010).