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http://dx.doi.org/10.5657/KFAS.2021.0271

Ultrasound-assisted Extraction for Development of Skin Whitening and Anti-wrinkling Cosmetic Materials from Spirulina platensis  

Kim, So Hee (Department of Food Science, Sun Moon University)
Jeon, Seong Jin (Department of Food Science, Sun Moon University)
Kim, Jun Hee (Department of Food Science, Sun Moon University)
Yeom, Suh Hee (Department of Food Science, Sun Moon University)
Kim, Jin Woo (Department of Food Science, Sun Moon University)
Publication Information
Korean Journal of Fisheries and Aquatic Sciences / v.54, no.3, 2021 , pp. 271-279 More about this Journal
Abstract
Ultrasound-assisted extraction (UAE) conditions, including extraction time, extraction temperature, and ethanol concentration, were optimized to increase the total flavonoid content (TFC), tyrosinase inhibitory activity (TIA), and collagenase inhibitory activity (CIA) of Spirulina platensis through central composite design (CCD). For the optimization of the three dependent variables, a quadratic regression model was derived from 17 experimental sets for the simultaneous maximization of TFC, TIA, and CIA. The predicted optimal UAE conditions were 44.0 min of extraction time, 82.8℃ of extraction temperature, and 96.0% of ethanol concentration. Under these conditions, 0.93 mg QE/g DM of TFC, 81.9% of CIA, and 92.1% of TIA were predicted. The CCD-based UAE optimization enabled an increase in TFC, CIA, and TIA, thereby confirming that the S. platensis extract can be used in the development of a cosmetic material with skin whitening and anti-wrinkle effects.
Keywords
Ultrasound-assisted extraction; Skin whitening; Anti-wrinkle; Optimization; Spirulina platensis;
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