Industry Promotion Research (산업진흥연구)

Industrial Promotion Institute (산업진흥원)
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Trends in Extraction Research and Types of Natural Substances Used for Skin Aging Prevention

피부노화 방지에 이용되는 천연물의 종류 및 추출연구 동향

  • 곽호석 (동양미래대학교 바이오융합공학과) ;
  • 전영상 (신한대학교 첨단소재공학과)
  • Received : 2024.03.27
  • Accepted : 2024.04.12
  • Published : 2024.04.30
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Abstract

The increase in the elderly population and growing interest in skin beauty, alongside specialized scientific examination of natural substances, have led to a rise in the utilization of natural materials. This paper investigates the types of natural substances, the functionality of extracts, and extraction technologies based on the literature that utilizes natural ingredients to mitigate skin aging. To directly assess the impact of functional materials derived from natural products on skin aging mitigation, the functionality of the extracts was determined based on their ability to synthesize Procollagen and reduce MMP-1. Each natural product is categorized into plants, herbal medicines, and microalgae in the literature utilizing the above evaluation methods. This paper describes the extraction technologies for securing functional materials from each ingredient and the main outcomes, providing trends in research on extraction technologies for functional materials aimed at alleviating skin aging

노인인구 증가와 피부미용에 관해 관심이 커지고 천연물에 대한 과학적 고찰의 전문화는 천연소재에 대한 활용 증가로 이어지고 있다. 본 논문은 천연원료를 피부노화 경감 소재로 활용한 문헌의 추출법 및 경감능을 기반으로 천연물의 종류, 추출물의 기능성 및 추출 기술을 조사하였다. 천연물 유래 기능성 소재의 피부노화 경감에 대한 직접적 영향을 평가하기 위해 콜라겐에 미치는 영향 중 Procollagen 합성능과 MMP-1 경감능을 기반으로 추출물의 기능성을 판단하였다. 각 천연물은 위의 평가법을 이용한 문헌 중 식물, 한약재 및 녹조류로 구분하여 각 원료로부터 기능성 소재의 확보를 위한 추출 기술과 주요 결과를 서술한다. 이에 따라 피부노화 완화를 위한 기능성 소재의 추출 기술과 연구 동향을 제공하여 천연물 활용 연구 분야에 신속한 접근을 제공한다.

Keywords

References

  1. Babara A. Gilchrest MD, "Skin aging and photoaging: An overview", Journal of the American Acad-emy of Dermatology, 21(3), 610-613, 1989. https://doi.org/10.1016/S0190-9622(89)70227-9
  2. Nami. Kim, Bonsuk. Goo, Seongkye. Lee, Euiil. Hwang, Seungho. So, Jaeho. Do, "Effect of Korean red ginseng on collagen biosynthesis and MMP-I activity in human dermal fibroblast", Journal of Ginseng Research, 31(2), 86-92, 2007. https://doi.org/10.5142/JGR.2007.31.2.086
  3. Hee-Sun Han, Song-Ja Bae, Mihyag Kim, "Effects of Porphyra tenera extracts on formation of collagen cross-ling in ovariectomized rats", 33(2), 324-330. 2004. https://doi.org/10.3746/jkfn.2004.33.2.324
  4. JF Bateman, SR Lamande, JAM Ramshaw. "Collagen Superfamily. In: Comper WD, editor. Extracellular Matrix", 2nd ed. Harwood Academic Publishers GmbH, Amsterdam, Netherlands. 22-67. 1996.
  5. J. C. Fantone, P. A. Ward. "Role of oxygen-derived free radicals and metabolites in leukocyte depend- ent inflammatory reaction". The American Journal of Pathology, 107(3), 397-418, 1982.
  6. K. J. Davies, M. E. Delsignore, S. W. "Protein damage and degradation by oxygen radical". Journal of Biological Chemistry, 262(20), 9902-9907, 1987. https://doi.org/10.1016/S0021-9258(18)48019-2
  7. Keum Ju Park, Seing Hee Park, Jae Ki Kim, "Anti- wrinkle Activity of Acanthopanax senticosus extract in Ultraviolet B-induced Photoaging", J. Korean Soc. Food Sci. Nutr., 39(1), 42-46, 2010. https://doi.org/10.3746/jkfn.2010.39.1.042
  8. Jung-Min Yoo, Yeo-Kin Kang, Hyeong-Bae Pyo, Eui-Su Choung, "Anti-wrinkle effects of Korean rice wine cake on human fibroblast", Journal of Life Science, 20(12), 1838-1843, 2010. https://doi.org/10.5352/JLS.2010.20.12.1838
  9. J. Parrado, M. Bourgria, A. Ayala, A. Castano, A. Machado, "Effects of aging on the various steps of protein synthesis: Fragmentation of elongation factors 2". Free Radical Biology & Medicine, 26(3-4), 362-370, 1999. https://doi.org/10.1016/S0891-5849(98)00202-0
  10. E. Yang, R. Jong, S. Kan,g, "The Effects of Genistein on the Proliferation and Type I pN Collagen Syn-thesis in Aged Normal HumanFibroblasts", Micro-biol. Biotechnol. Leet., 35(4), 316-324, 2007.
  11. G.J. Fisher, G.J. Datta, H.S. Talwar, Z.Q. Wang, J. Varani, S. Kang, J. J. Voorhees. "Molecular basis of sun-induced premature skin aging and retinoid antagonism". Nature, 379, 335-339, 1996. https://doi.org/10.1038/379335a0
  12. Kang S, Chung JH, Lee JH, Fisher GJ, Wan YS, Duell EA, Voorhees JJ. Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo. J. Invest. Dermatol., 120, 835-841, 2003. https://doi.org/10.1046/j.1523-1747.2003.12122.x
  13. G.J. Clydesdale, G.W. Dandie, H.K. Mueller, Ultra-violet light induced injury: Immunological and inflammatory effects, Immunol. Cell Biol., 79(6), 547, 2001.
  14. E.J. Kim, M.K. Shim, R. Jeong, A. Kim, "Anti- photoaging Effects of Fermented Soybean (Bio- Peptone®)", J. Soc. Cosmet. Scientists Korea, 45(1), 27-36, 2019.
  15. J. Yang and C. Kwak, "Inhibitory effect of Aralia elata ethanol extract against skin damage in UVB- exposed human keratinocytes and human dermal fibroblasts", J. Nutr. Health., 49(6), 429, 2016.
  16. H. J. Kim, K. S. Kim, and D. I. Kim, "Inhibitory effects of Lespedeza cuneata ethanol extract on ultraviolet-induced photo aging", J Korean Soc Food Sci Nutr, 41(11), 1540, 2012.
  17. Paul S. "Fish bone chemistry and ultrastructure: Implications for taphonomy and stableisotope analysis", J. Archaeol. Sci., 38, 3358-3372, 2011. https://doi.org/10.1016/j.jas.2011.07.022
  18. Y. J. Kim, Y. Yoon, "Regulation of Col1A1 and MMP1 Expression by Taurine, Major Component of Oyster, in Human Dermal Fibroblasts", Asian J. Beauty Cosmetol, 11(2), 393-397, 2013.
  19. P. Elsner, D. Wilhelm, H. I. "Maibach. Mechanical properties of human forearm and vulvar skin", Br J Dermatol, 122, 607-614, 1990. https://doi.org/10.1111/j.1365-2133.1990.tb07282.x
  20. D. J. Prockop, R. A. Berg, K. I. Kivirikko, J. Uitto, "Intracellular steps in the biosynthesis of collagen, Biochemistry of Collagen", In: Ramachandran GN, Reddi AH, editor. Plenum Press, New York; 1976. 163-273.
  21. Jemec G, Jemec B, Jemec BIE. The effect of superficial hydration the mechanical properties of human skin in vivo. Plast Reconstr Surg., 85, 100-103, 1990. https://doi.org/10.1097/00006534-199001000-00017
  22. S. R. Pinnell, S. Murad, D. Darr, "Induction of collagen synthesis by ascorbic acid. A possible Mechanism", Arch Dermatol, 123, 1684-1686, 1987. https://doi.org/10.1001/archderm.1987.01660360122023
  23. J. E. Kim, J. Lee, H. Kim, J. Kim, Y. Cho, "Effect of Vitamin C, Silicon and Iron on Collagen Synthesis and Break-Down Enzyme Expression in the Human Dermal Fibroblast Cell (HS27)", Korean J. Nutr., 42(6), 505-515, 2009. https://doi.org/10.4163/kjn.2009.42.6.505
  24. J. J. Cho, G. K. Lee, B. K. Cho, J. D. Choi, "Isolation and characterization of elastase inhibitor from Areaca catechu", J. Soc. Cos. Sci. Kor., 26, 23-27, 2000.
  25. J.S. Hwang, "The effects of retinoids on Crabp II mRNA induction and collagen synthesis in human dermal fibroblast", J. Soc. Cos. Sci. Kor. 23, 9-14, 1997.
  26. B. J. Kim, B. K. Jo and J. H. Kim. "A promising new anti-wrinkle ingredient: Pericarpium castaneae extracts", J. Soc. Cos. Sci. Kor., 10, 56-62, 1999.
  27. C. W. Lee, H. B. Pyo, Y. H. Cho and S. M. Park. "Effect of Korean black soybean seed on the cellular proliferation and the production of type III collagen in skin fibroblast", J. Soc. Cos. Sci. Kor. 24, 31-38. 1998.
  28. S.K. Park, M.Y. Chang, Y.D. Kim, B.Y. Jeong, Y.H. Won, J.J. Kim and S.H. Kang. "Changes of facial wrinkle after topical application of on emulsion containing medimin A", J. Soc. Cos. Sci. Kor. 25, 22-29. 1999. https://doi.org/10.4070/kcj.1999.29.1.22
  29. J. Kang, S. Hyun, H. Kim, D. Yoo, H. Choi, I Lee, "Antioxidant and pro-collagen synthesis activities of the Eriobotrya japonica leaf extract using enzyme", Asian J. Beauty Cosmetol., 21(2), 263-270. 2023. https://doi.org/10.20402/ajbc.2023.0027
  30. Yue-xian Wu, Tun-yu Jian, Han Lv, Xiao-qin Ding, Yuan-yuan Zuo, Bing-ru Ren, Jian Chen, Wei-lin Li, "Antitussive and expectorant properties of growing and fallen leaves of loquat (Eriobotrya japonica)", Revista Brasileira de Farmacognosia, 28(2), 239- 242,
  31. H. Cory, S. Passarelli, J. Szeto, M. Tamez, J. Mattei, "The role of polyphenols in human health and food systems: A mini-review", Front. Nutr., 21(5) 87, 2018. 
  32. H. M. Jo, I. H. Choi, "A study on antioxidant, pro- collagen synthesis and MMP-1 inhibitory activities of Saliva microphylla extract", Asian J. Beauty Cosmetol., 21(4), 665-674, 2023. https://doi.org/10.20402/ajbc.2023.0087
  33. J. Kim, Y. Choi, H. K. Kim, Y. Jang, "Collagen synthesis ability and inhibitory effect of MMPs in keratinocytes of Lysimachia christinae Hance extract", J. Korean Applied Sci. Tech., 37(4), 820-829, 2020.
  34. S.Y. Park, S.J. Lee, "The Effects of Prunus yedoensis Flowers Biorenovate Extract on Collagen Synthesis and Expression in Human Dermal Fibroblasts", J. Invest Cosmetol., 16(4), 323-330, 2020.
  35. E. Park, S. Kim, S. J. Moon, "The Effects of Marigold (Tagetes L.) Extract and Calendula (Calendula officinalis L.) Extract on Collagen Growth and MMP-1 Expression in Human Dermal Fibroblasts", KOCS, 34(4), 769-777, 2017.
  36. J. Kang, I. Lee, "Anti-inflammatory and matrix metallopeptidase-1-inhibitory effects of the Cassia obtusifolia L. seed extract on particulate matter- induced skin", Asian J. Beauty Cosmetol., 19(3), 355-363, 2021. https://doi.org/10.20402/ajbc.2021.0183
  37. J. Lee, S. Park, S. Kang, "c-Jun/MMP-1 Inhibitory Effect of Rhododendron brachycarpum via Reactive Oxygen Species (ROS) Regulation", J. Invest. Cosmetol., 13(4), 313-319, 2017. https://doi.org/10.15810/jic.2017.13.4.002
  38. Y. Jeong, J. Y. Lee, J. Ko, "Inhibitory Effect of Lonicera japonica Extract on MMP-1 Production in Human Dermal Fibroblast", J. Soc. Cos. Sci. Kor., 46(1), 67-72, 2020.
  39. J. Hwang, H. Baik, B. Park, Y. C. Kim, "Anti-aging Efficacy of Tradescantia reflexa Methanol Extract in Human Dermal Fibroblasts", 11(1), 25-32, 2015. https://doi.org/10.15810/JIC.2015.11.1.004
  40. H.S. Heong, D.H. Lee, M. Lee, T. Heo, D.W. Kim, "Anti-aging and ant-inflammatory activities of the extracts of Calamagrostis arundinacea," Journal of Life Science, 31(3) 298-304, 2021. https://doi.org/10.5352/JLS.2021.31.3.298
  41. J. Kim, H. Sohn, "Skin Whitening and Anti-Wrinkle Effects of Extract from Jubak of Oriental Herbal Liquor", J. Korean Soc. Food Sci. Nutr, 43(11), 1695-1700, 2014. https://doi.org/10.3746/jkfn.2014.43.11.1695
  42. C.J. Krishna, P. Singh, R.T. Pardasani, "Chemical components of the roots of Tectona grandis and Gmelina arborea", 32(1), 71-75, 1977. https://doi.org/10.1055/s-0028-1097561
  43. J. W. Kang, J. Y. Oh, J. Bae, J. Kim, K. Lee, H. Pyo, "Effects of Autoclaved Morinda officinalis Root Extract on the Suppressive Efficacy of MMP-1 En- zyme", J. Soc. Cos. Sci. Kor., 41(1), 35-43, 2015. https://doi.org/10.15230/SCSK.2015.41.1.35
  44. Y. Kim, S. Ko, "Inhibition of MMP-1 Expression and Collagen Synthesis Activity of Ultrasonication Processed Ginseng Flower Buds Extract", Nat. Prod. Sci., 46(2), 154-159, 2015.
  45. S.J. Choi, S. Lee, K. Kim, D.H. Joo, S. Shin, J. Lee, H.K. Lee, J. Kim, S.B. Kwon, M.J. Kim, K.J. Ahn, I. An, S. An, H.J. Cha, "Biological effects of rutin on skin aging", International Journal of Molecular Medicine, 38(1), 201.,
  46. H. Lee, S. Hong, H. Heo, H. Choe, H. Jeong, J. Lee, "Protective Effects of Methanol Extract from Acanthopanacis cortex Shoots against Photoaging in Human Skin Fibroblast", J. Korean Soc. Food Sci. Nutr., 48(3), 385-389, 2019. https://doi.org/10.3746/jkfn.2019.48.3.385
  47. T. Pattananandecha, S. Apichai, J. Julsrigival, M. Ungsurungsie, S. Samuhasaneetoo, P. Chulasiri, P. Kwankhao, S. Pitiporn, F. Ogata, N. Kawasaki, C. Saenjum, "Antioxidant activity and anti-photoaging effects on UVA-irradiated human fibroblasts of rosmarinic acid enriched extract prepared from Thunbergia laurifolia leaves", 11, 1648, 2021.
  48. S. Choi, H. Park, J. Lee, "Isolation of Chlorella vulgaris mutants producing high pilid and their characterization", Appl. Chem. Eng., 26(5), 533- 537, 2015. https://doi.org/10.14478/ace.2014.1135
  49. J. Joo, J. Seok, I. Hong, N. Kim, E. Choi, "Inhibitory Effects of Dunaliella salina Extracts on Thermally-Induced Skin Aging", J. Soc. Cos. Sci. Kor., 42(1), 57-64, 2016. https://doi.org/10.15230/SCSK.2016.42.1.57
  50. J.W. Hong, H.Y. Suh, Y.S. Oh, J.H. Park, M.H. Kang, Y.H. Kim, Z. Kim, K.J. Yim, K.W. Kim, "Enhancement of Collagen Synthesis through the Regulations of MMP-1,COL1A1, and SMAD-3 by Extract of the Freshwater Microalgae Mychonastes sp. 249", J. Korean Soc. Food Sci. Nutr., 52(2), 203-209, 2013. https://doi.org/10.3746/jkfn.2023.52.2.203