• Title/Summary/Keyword: Simulated biological model

Search Result 121, Processing Time 0.02 seconds

Development and Application of Integrated System with SATEEC, nLS and USPED for Gully Erosion Evaluation (걸리 침식 평가를 위한 SATEEC, nLS, USPED 연계 시스템의 개발 및 적용)

  • Kang, Hyunwoo;Park, Youn Shik;Kim, Nam Won;Ok, Yong Sik;Jang, Won Seok;Ryu, Ji Chul;Kim, Ki-Sung;Lim, Kyoung Jae
    • Journal of Korean Society on Water Environment
    • /
    • v.26 no.4
    • /
    • pp.637-647
    • /
    • 2010
  • The Universal Soil Loss Equation (USLE)-based modeling systems have been widely used to simulate soil erosion studies. However the GIS-based USLE modeling systems have limitation in gully erosion evaluation which is one of the most important factor in soil erosion estimation. In this study, the integrated soil erosion evaluation system using with Sediment Assessment Tool for Effective Erosion Control (SATEEC) system, nLS and Unit Stream Power-based Erosion/Deposition (USPED) model was developed to simulate gully erosion. Gully head location using nLS model, USPED for gully erosion, and the SATEEC estimated sheet and rill erosion were evaluated and combined together with the integrated soil erosion evaluation system. This system was applied to the Haean-myeon watershed, annual average sediment-yield considering sheet, rill and gully erosion was simulated as 101,933 ton/year at the study watershed. if the integrated soil erosion evaluation system is calibrated and validated with the measured data, this system could be efficiently used in developing site-specific soil erosion best management system to reduce soil erosion and muddy water inflow into the receiving waterbody.

A Numerical Analysis on the Hemodynamic Characteristics in Elastic Blood Vessel with Stenosis (협착이 있는 탄성혈관을 흐르는 혈액의 유동특성에 관한 수치해석적 연구)

  • 정삼두;김창녕
    • Journal of Biomedical Engineering Research
    • /
    • v.23 no.4
    • /
    • pp.281-286
    • /
    • 2002
  • In this study, blood flow in a carotid artery supplying blood to the human's brain has been numerically simulated to find out how the blood flow affects the genesis and the growth of atherosclerosis and arterial thrombosis. Velocity Profiles and hemodynamic parameters have been investigated for the carotid arteries with three different stenoses under physiological flow condition. Blood has been treated as Newtonian and non-Newtonian fluid. To model the shear thinning properties of blood for non-Newtonian fluid, the Carreau-Yasuda model has been employed. The result shows that the wall shear stress(WSS) increases with the development of stenosis and that the wall shear stress in Newtonian fluid is highly evaluated compared with that in non-Newtonian Fluid. Oscillatory shear index has been employed to identify the time-averaged reattachment point and this point is located farther from the stenosis for Newtonian fluid than for non-Newtonian fluid The wall shear stress gradient(WSSG) along the wall has been estimated to be very high around the stenosis region when stenosis is developed much and the WSSG peak value of Newtonian fluid is higher than that of non-Newtonian fluid.

Numerical Analysis of the Blood Flow in the Korean Artificial Heart Using Two Dimensional Model (2차원 모델을 이용한 한국형 인공심장 내 혈액 유동에 대한 수치적 해석)

  • 박명수;심은보;고형종;사종엽;박찬영;민병구
    • Journal of Biomedical Engineering Research
    • /
    • v.24 no.4
    • /
    • pp.301-307
    • /
    • 2003
  • In this study, we Presented computational results on the blood flow in the sac of the Korean artificial heart. Two dimensional unsteady flow was assumed and we utilized a finite element commercial code ADINA to simulate the blood flow. Rigid body-solid contact were considered between the actuator and the blood sac and fluid-structure interaction between the blood and the sac. The three geometric models proposed in the design process were simulated to assess the hemodynamic characteristics of the models According to the computational results, a strong flow to the outlet and a stagnated flow region near the inlet were observed during systole. The sac was filled with blood and recirculating flow was generated near the outlet during diastole. Shear stress during systole had its extreme values near the outlet edge whereas the magnitude of shear stress values were relative)v high near the inlet edge and the contacting surface with the actuator.

A Study of Orthognathic Surgical Guides with Two-stage Split Path (2단 절개 형태를 가지는 악교정 수술 장치 연구)

  • Min Uk, Kim;Chung Hwan, Park;Ji Hyoung, Rho;Eui Sung, Jung;Young Sang, Park;Dong Guk, Kim;Yohan, Seo;Young Jea, Woo;Jong Min, Lee
    • Journal of Biomedical Engineering Research
    • /
    • v.43 no.6
    • /
    • pp.382-389
    • /
    • 2022
  • In this study, the accuracy of the orthognathic surgical guides with single-stage split path was upgraded to realize orthognathic surgical guides with two-stage split path and simulated surgery was performed to verify its accuracy. As a result, the average error distance between the simulation model and the scan model was + 0.289 / - 0.468 mm (standard deviation 0.128), which was confirmed to be within ± 0.5 mm, which is a clinically acceptable level. Also, there was no significant difference compared with the average value of + 0.313 / - 0.456 mm (average standard deviation 0.106) of the conventional single-stage split path type device. It is judged that the use of this device can contribute to the reduction of surgical time and increase in accuracy since a separate finishing operation for bone preparation is unnecessary.

Modeling the long-term vegetation dynamics of a backbarrier salt marsh in the Danish Wadden Sea

  • Daehyun Kim
    • Journal of Ecology and Environment
    • /
    • v.47 no.2
    • /
    • pp.49-62
    • /
    • 2023
  • Background: Over the past three decades, gradual eustatic sea-level rise has been considered a primary exogenous factor in the increased frequency of flooding and biological changes in several salt marshes. Under this paradigm, the potential importance of short-term events, such as ocean storminess, in coastal hydrology and ecology is underrepresented in the literature. In this study, a simulation was developed to evaluate the influence of wind waves driven by atmospheric oscillations on sedimentary and vegetation dynamics at the Skallingen salt marsh in southwestern Denmark. The model was built based on long-term data of mean sea level, sediment accretion, and plant species composition collected at the Skallingen salt marsh from 1933-2006. In the model, the submergence frequency (number yr-1) was estimated as a combined function of wind-driven high water level (HWL) events (> 80 cm Danish Ordnance Datum) affected by the North Atlantic Oscillation (NAO) and changes in surface elevation (cm yr-1). Vegetation dynamics were represented as transitions between successional stages controlled by flooding effects. Two types of simulations were performed: (1) baseline modeling, which assumed no effect of wind-driven sea-level change, and (2) experimental modeling, which considered both normal tidal activity and wind-driven sea-level change. Results: Experimental modeling successfully represented the patterns of vegetation change observed in the field. It realistically simulated a retarded or retrogressive successional state dominated by early- to mid-successional species, despite a continuous increase in surface elevation at Skallingen. This situation is believed to be caused by an increase in extreme HWL events that cannot occur without meteorological ocean storms. In contrast, baseline modeling showed progressive succession towards the predominance of late-successional species, which was not the then-current state in the marsh. Conclusions: These findings support the hypothesis that variations in the NAO index toward its positive phase have increased storminess and wind tides on the North Sea surface (especially since the 1980s). This led to an increased frequency and duration of submergence and delayed ecological succession. Researchers should therefore employ a multitemporal perspective, recognizing the importance of short-term sea-level changes nested within long-term gradual trends.

Computational Fluid Dynamics Study of Channel Geometric Effect for Fischer-Tropsch Microchannel Reactor (전산유체역학을 이용한 Fischer-Tropsch 마이크로채널 반응기의 채널 구조 영향 분석)

  • Na, Jonggeol;Jung, Ikhwan;Kshetrimayum, Krishnadash S.;Park, Seongho;Park, Chansaem;Han, Chonghun
    • Korean Chemical Engineering Research
    • /
    • v.52 no.6
    • /
    • pp.826-833
    • /
    • 2014
  • Driven by both environmental and economic reasons, the development of small to medium scale GTL(gas-to-liquid) process for offshore applications and for utilizing other stranded or associated gas has recently been studied increasingly. Microchannel GTL reactors have been prefrered over the conventional GTL reactors for such applications, due to its compactness, and additional advantages of small heat and mass transfer distance desired for high heat transfer performance and reactor conversion. In this work, multi-microchannel reactor was simulated by using commercial CFD code, ANSYS FLUENT, to study the geometric effect of the microchannels on the heat transfer phenomena. A heat generation curve was first calculated by modeling a Fischer-Tropsch reaction in a single-microchannel reactor model using Matlab-ASPEN integration platform. The calculated heat generation curve was implemented to the CFD model. Four design variables based on the microchannel geometry namely coolant channel width, coolant channel height, coolant channel to process channel distance, and coolant channel to coolant channel distance, were selected for calculating three dependent variables namely, heat flux, maximum temperature of coolant channel, and maximum temperature of process channel. The simulation results were visualized to understand the effects of the design variables on the dependent variables. Heat flux and maximum temperature of cooling channel and process channel were found to be increasing when coolant channel width and height were decreased. Coolant channel to process channel distance was found to have no effect on the heat transfer phenomena. Finally, total heat flux was found to be increasing and maximum coolant channel temperature to be decreasing when coolant channel to coolant channel distance was decreased. Using the qualitative trend revealed from the present study, an appropriate process channel and coolant channel geometry along with the distance between the adjacent channels can be recommended for a microchannel reactor that meet a desired reactor performance on heat transfer phenomena and hence reactor conversion of a Fischer-Tropsch microchannel reactor.

Structural and Solubility Characteristics of Coenzyme Q10 Complexes Including Cyclodextrin and Starch (사이클로덱스트린과 전분을 이용한 coenzyme Q10 복합체의 특성 연구)

  • Lee, Joon-Kyoung;Lee, Hyun-Joo;Lim, Jae-Kag
    • Korean Journal of Food Science and Technology
    • /
    • v.46 no.2
    • /
    • pp.180-188
    • /
    • 2014
  • This study focused on assessing the solubility and structural characteristics of two types of coenzyme $Q_{10}$ ($CoQ_{10}$) complexes: the $CoQ_{10}$-starch and the $CoQ_{10}$-cyclodextrin complexes. The solubility of $CoQ_{10}$-starch complex increased significantly as the temperature was increased. However, the solubility of $CoQ_{10}$-cyclodextrin complex reached a peak at $37^{\circ}C$, and strong aggregation occurred at $50^{\circ}C$. When the temperature was raised to $80^{\circ}C$, the $CoQ_{10}$-cyclodextrin complex dissociated owing to the weakening of bonds, resulting in $CoQ_{10}$ emerging at the surface of water. Therefore, $CoQ_{10}$-cyclodextrin complexes have lower solubility, due to their reduced heat-stability, than do the $CoQ_{10}$-starch complexes. Structural differences between the two $CoQ_{10}$ complexes were confirmed by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffractometer (XRD), and differential scanning calorimeter (DSC). The $CoQ_{10}$-cyclodextrin complex included an isoprenoid chain of $CoQ_{10}$, while the $CoQ_{10}$-starch complex included both the benzoquinone ring and the isoprenoid chain of $CoQ_{10}$. These results suggest that $CoQ_{10}$-starch complexes possess higher heat-stability and solubility than do the $CoQ_{10}$-cyclodextrin complexes.

Analysis of Oscillometric Model based on Shape of Arterial Pressure (동맥압 형태를 고려한 오실로메트릭 모델분석)

  • 임성수;이경중
    • Journal of Biomedical Engineering Research
    • /
    • v.21 no.4
    • /
    • pp.411-417
    • /
    • 2000
  • This paper describes the analysis of the oscillometric method based on the shape of arterial pressure and proposal of a new algorithm for estimating the blood pressure by computer simulation. In the first step, the arterial pressure model which is able to control the shape of arterial pressure was designed and then we simulated the oscillometric model using both the existing exponential model showing the static arterial pressure-volume relation and the designed arterial pressure model. By analyzing the correlation of characteristic ratio based on the shape of arterial pressure, we could find that the characteristic ratio was not the only standard parameter for estimating systolic and diastolic pressure. We were able to estimate the shape of arterial pressure by computing the correlation of arterial pressure shape with oscillation shape. Finally, we proposed an algorithm which is able to estimate systolic and diastolic pressure according to pressure(Pp) table constructed from the relation of maximum amplitude of oscillation and arterial pressure shape. We tested 60 arterial pressure waveforms having various arterial pressure shape and pulse. As a results, the absolute deviation average values of the estimation of systolic, diastolic and mean pressure were 1.62%, 2.40% and 2.20%, respectively. In conclusions, the proposed algorithm showed the possibility of usefullness in estimating the blood pressure.

  • PDF

Feasibility Study of EEG-based Real-time Brain Activation Monitoring System (뇌파 기반 실시간 뇌활동 모니터링 시스템의 타당성 조사)

  • Chae, Hui-Je;Im, Chang-Hwan;Lee, Seung-Hwan
    • Journal of Biomedical Engineering Research
    • /
    • v.28 no.2
    • /
    • pp.258-264
    • /
    • 2007
  • Spatiotemporal changes of brain rhythmic activity at a certain frequency have been usually monitored in real time using scalp potential maps of multi-channel electroencephalography(EEG) or magnetic field maps of magnetoencephalography(MEG). In the present study, we investigate if it is possible to implement a real-time brain activity monitoring system which can monitor spatiotemporal changes of cortical rhythmic activity on a subject's cortical surface, neither on a sensor plane nor on a standard brain model, with a high temporal resolution. In the suggested system, a frequency domain inverse operator is preliminarily constructed, considering the individual subject's anatomical information, noise level, and sensor configurations. Spectral current power at each cortical vertex is then calculated for the Fourier transforms of successive sections of continuous data, when a single frequency or particular frequency band is given. An offline study which perfectly simulated the suggested system demonstrates that cortical rhythmic source changes can be monitored at the cortical level with a maximal delay time of about 200 ms, when 18 channel EEG data are analyzed under Pentium4 3.4GHz environment. Two sets of artifact-free, eye closed, resting EEG data acquired from a dementia patient and a normal male subject were used to show the feasibility of the suggested system. Factors influencing the computational delay are investigated and possible applications of the system are discussed as well.

Dynamic Characterization of Fall for Development of Fracture Prevention System (골절 방지 시스템의 개발을 위한 낙상 동적 특성 분석)

  • Kim, Seong-Hyun;Kim, Yong-Yook;Kwon, Tae-Kyu;Kim, Dong-Wook;Kim, Nam-Gyun
    • Journal of Biomedical Engineering Research
    • /
    • v.28 no.6
    • /
    • pp.811-816
    • /
    • 2007
  • The social activities of the elderly have been increasing as our society progresses toward an aging society. As their activities are increased, the occurrence of falls that could lead to fractures are increased. Falls are serious health hazards to the elderly and we need more thorough understanding of falls including the progress of falls and the impact area in various fall directions. Many of the traditional methods of falls research dealt with voluntary falls by younger subject since older subject can easily get fracture from voluntary falls. So, it has been difficult to get exact data about falls of the elderly. Here, we tried to capture the characteristics of the movements of major joints using three dimensional motion capture system during falls experiments using a moving mattress that can safely induce unexpected falls. Healthy younger subjects participated in the actual falls experiment and the moving mattress was actuated by a pneumatic system. The kinematic parameters such as velocities and accelerations of major segments were imported to a computer simulation environment and falls to hard surfaces were simulated in a computational environment using a realistic human model of aged persons. The simulation was able to give approximations to contact forces which can occur during actual falls.