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http://dx.doi.org/10.9721/KJFST.2014.46.2.180

Structural and Solubility Characteristics of Coenzyme Q10 Complexes Including Cyclodextrin and Starch  

Lee, Joon-Kyoung (Department of Biological Science and Chemical Technology, Korea Polytechnic University)
Lee, Hyun-Joo (Department of Biological Science and Chemical Technology, Korea Polytechnic University)
Lim, Jae-Kag (Department of Biological Science and Chemical Technology, Korea Polytechnic University)
Publication Information
Korean Journal of Food Science and Technology / v.46, no.2, 2014 , pp. 180-188 More about this Journal
Abstract
This study focused on assessing the solubility and structural characteristics of two types of coenzyme $Q_{10}$ ($CoQ_{10}$) complexes: the $CoQ_{10}$-starch and the $CoQ_{10}$-cyclodextrin complexes. The solubility of $CoQ_{10}$-starch complex increased significantly as the temperature was increased. However, the solubility of $CoQ_{10}$-cyclodextrin complex reached a peak at $37^{\circ}C$, and strong aggregation occurred at $50^{\circ}C$. When the temperature was raised to $80^{\circ}C$, the $CoQ_{10}$-cyclodextrin complex dissociated owing to the weakening of bonds, resulting in $CoQ_{10}$ emerging at the surface of water. Therefore, $CoQ_{10}$-cyclodextrin complexes have lower solubility, due to their reduced heat-stability, than do the $CoQ_{10}$-starch complexes. Structural differences between the two $CoQ_{10}$ complexes were confirmed by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffractometer (XRD), and differential scanning calorimeter (DSC). The $CoQ_{10}$-cyclodextrin complex included an isoprenoid chain of $CoQ_{10}$, while the $CoQ_{10}$-starch complex included both the benzoquinone ring and the isoprenoid chain of $CoQ_{10}$. These results suggest that $CoQ_{10}$-starch complexes possess higher heat-stability and solubility than do the $CoQ_{10}$-cyclodextrin complexes.
Keywords
coenzyme $Q_{10}(CoQ_{10})$-starch complex; coenzyme $Q_{10}(CoQ_{10})$-cyclodextrin complex; heat-stability; solubility capability; structural characteristic;
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Times Cited By KSCI : 5  (Citation Analysis)
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