• Journal of Veterinary Clinics
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• v.13 no.2
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• pp.127-129
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• 1996

The study was conducted to determine normal blood and serum chemical values on deer. Normal blood and serum chemical values were studied in 8 healthy deers bred at Dalseung Park in Taegu. The values were analyzed with a blood chemical analyzer and calculated by Chawen's statistical analysis. The blood values of RBC, WBC and PCV were $9.73{\pm}1.19{\times} 10^{6}/{\mu}l, 3.37{\pm}0.88{\times}10^{3}/{\mu}l, 47.25{\pm}4.65 % respectively. The serum chemical value were: GOT; 83.0{\pm}39.4 IU/L, GPT; 50.12{\pm}25.83 IU/L, BUN; 36.63{\pm}8.70 mg/dl. CPK ; 1,296{\pm}495 IU/L, ALP; 238{\pm}54 IU/L, glucose; 143{\pm}52 mg/dl, total protein; 6.95{\pm}0.61 g/dl, amylase ; 116.0{\pm}34.5 IU/L,$ respectively. These values will be clinically helpful to diagnose the disease of deer.

• Korean Journal of Veterinary Service
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• v.15 no.2
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• pp.128-133
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• 1992

To obtain the basic data for blood chemistry, the effects of the time elapse of serum separation on bovine blood chemical values were investigated. The results obtained are summerized as follows : 1. The constant fluctuation tendency and significance was not detected in GOT, GPT, BUN, Creatinine, ALP, CPX, Cholesterol, Ca, Mg and Pi. 2. Glucose showed the decrease tendency according to the time elapse of serum separation. As the values at 12 and 24 hours showed significant lower values than those at 1 and 2 hours (p＜0.01) it was thougth that separation time of serum should be focussed for the glucose determination.

• Journal of Environmental Science International
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• v.22 no.4
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• pp.463-469
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• 2013

This study was conducted to investigate the effects of the Cordyceps militaris extract on the improvement of the glucide metabolism in serum of streptozotocin (STZ, 50 mg/kg BW, IP injection)-induced diabetic rats (SD strain, male) fed the experimental diets for 5 weeks. Concentrations of creatinine, lipid peroxide and NEFA in sera were significantly higher in the STZ-induced diabetic group (group DMG) and STZ+Cordyceps militaris extract administration group (group DMS) than those in the control group (group BD). However, the concentrations of creatinine, lipid peroxide and NEFA in sera were reduced in the group DMS than those in the group DMG. The activity of creatine phosphokinase (CPK) in serum was lower in the group DMS than in the group DMG. The activity of LCAT in serum was increased in the group DMS (Cordyceps militaris extract administration) than in the group DMG. The results indicate that Cordyceps militaris extract were effective in the improvement of the glucide metabolism in the sera of STZ-induced diabetic rats.

• Journal of Veterinary Clinics
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• v.17 no.2
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• pp.349-358
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• 2000

Effects of repeated administration of diminazene aceturate (Hoechst Veterin r GmbH. Ger- many) that has been introduced as effective compound against Babesiosis and trppanosomiasis were investigated in dogs experimentally infacted with Babesia gibsoni. Adull mongrel dogs of both sexes were inoculated will nonpreserved infected blood and then maintained chronic anemia. A single dose of diminazene aceturate of 7mg/kg b.w. was administrated intramnuscularIy on day 7.1 arid ,7. Clin- ical and hcmatological findings following inoculation and medication were observed and 7enlm bio chemical analysis also was monitored. Parasitemia was detected between 3 and 6 days after inoculation. The rate of parasitized erythrocytes,1 in peripheral blood reached the peak on the 13th day and was maintained the percentage of 0.1 to 1.0 until the medication of diminazene aceturate. RBC was significantly (p<0.01) decreased on the 3rd day and then kept on decreasing. The lowest value was observed on the 16th day. WBC remained generally within normal ranges. PCV revea1ed the sig-nificant (p<0.01) decrease within the range of 24-27% and platelet was significantly (p<0.05) decreased during the period. Senum chemical values (ALT, AST. total bilirubin. LDH BUN, area- tinine, total protein. albumin and glucose) were within normal ranges during the experimental period. Serum CPK values were significantly (p<0.01) increased on the 3rd day. There was no clinically, sig-nificant difference in a single dose of diminazene aceturate of 7 mg/kg b.w. But the administration of diminazene aceturate of 14 mg/kg b.w. revealed vomiting and anorexia and one dog died in 30 hours after administration. The administration of 14mg/kg b.w. resulted in vomiting, salivation, actor- exia, tremor of head and involuntary movement and one dog died in 27 hours after administration. WBC, RBC, PCV and Platelet values were no significant difference and hematological findings revealed persistent anemia and thrombocytopenia during chronic anemia after inoculation. AST activity its was significantly (p<0.01) increased 11\\`from 3 days after medication and AST activity was on the same trend. Serum CPK activity revealed significant (p<0.01) increase within 6 hors)\\`s after every administration and decreased in 48 howl·s after administration.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.268-272
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• 1997

This study was performed to estimate the clinical signs and biochemical para meters of indicator on acute hepatic injury induced by the administration of CCl$_{4}$ in rats. Minor behavioral changer brittleness of skin hair and decreased volume of water and food intake were observed in rats after 2 hours of $CCl_{4}$ administration compared to control group. Concentration of serum albumin has shown lower than that of control group. However concentration of total bilirubin has shown higher than that of control group. As times go onto serum LDH activity was significantly increased compared to control Broup. Serum CPK activity hasn't shown change compared to control group. Passive hemagglutination that of afetoprotein was shown negative reaction in all the treatment groups and control group.

• Journal of Environmental Science International
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• v.21 no.10
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• pp.1213-1219
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• 2012

The objective of this study was to investigate the effects of the feeding Cordyceps militaris extract on the improvement of the free fatty acid, lipid peroxide, creatinine and enzyme (creatine phosphokinase; CPK, lactate dehydrogenase; LDH, alkaline phosphatase; ALP, lecithin cholesterol acyltransferase; LCAT) activities in the sera of dietary hypercholesterolemic rats (SD strain, male) fed the experimental diets for 5 weeks. Concentrations of free fatty acid, lipid peroxide and CPK, LDH, ALP activities in sera were fairly reduced in the Cordyceps militaris extract administration group (CHE) than in the hypercholesterolemic diet group (CHD). However, no significance was found in the effect of an creatinine concentration among the groups. The LCAT activity in serum was increased in the Cordyceps militaris extract administration (CHE) than in the hypercholesterolemic diet group (CHD). From these results, Cordyceps militaris extracts were effective on the improvement of the lipid components and metabolic enzyme activities in sera of dietary hypercholesterolemic rats.

• Journal of Veterinary Clinics
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• v.15 no.1
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• pp.162-170
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• 1998

Present experiments were undertaken in order to determine the normal hematological and blood chemical values of elks raised in Korea. Blood samples were collected from 22 healthy adult (5~10 years old) male elks raised in Kyung-pook prefecture and examined for 9 hematological and 15 blood chemical parameters using automatic blood cell counter and automatic blood chemical analyzer. The mean hematological values were determined as PCV : 34.23%, RBC count : $6.70{\times}10^{6}/{\mu}l, Hb : 12.15g/61, WBC count : 3.17{\times}10^{3}/{\mu}l$, neutrophil : 54.09%, eosinophil : 12.27%, Iymphocyte : 28.86%, monocyte : 5.23%, and platelet : $39.94$\times$10^{5}/{\mu}l$

• Journal of the Korean Society of Physical Medicine
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• v.17 no.1
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• pp.31-39
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• 2022

PURPOSE: This study examined the changes in the blood fatigue variables caused by isokinetic and isotonic exercise training. METHODS: Ten healthy adult males with at least one year of athletic experience participated. The participants performed the isokinetic circuit exercise program first, followed by an isotonic circuit exercise program. A two-hour break was allowed between the isokinetic circuit exercise program and the isotonic circuit exercise program. The circuit exercise program consisted of four items (Squat, Deadlift, Shoulder press, and Bench press). The blood samples were analyzed for the LDH, CPK, and Cortisol levels. RESULTS: The LDH level in the isokinetic group was significantly different from the isotonic group. In particular, the change in LDH level in the isokinetic group was 33.30% lower than that of the isotonic group. The serum CPK level of the isokinetic group showed a 10.03% lower decrease than the isotonic group, but the difference was not significant. The Cortisol level was relatively unchanged in the isotonic group, but it decreased in the isokinetic group. On the other hand, the Cortisol level did not show a significant difference between the two groups. CONCLUSION: The isokinetic group showed alleviation of the three indices, unlike the isotonic group. Further studies associated with the changes in blood fatigue variables through various exercise programs and exercise intensity will be needed.

• Journal of Korean Neurosurgical Society
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• v.48 no.3
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• pp.225-229
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• 2010

Objective : The authors introduce a minimally invasive muscle sparing transmuscular microdiscectomy (MSTM) to treat herniated lumbar disc disease. Its results are compared with conventional subperiosteal microdiscectomy (CSM) to validate the effectiveness. Methods : Muscle sparing transmuscular microdiscectomy, which involves muscle dissection approach using the natural fat cleavage plane between the multifidus to expose the interlaminar space, was performed in 23 patients to treat a single level unilateral lumbar radiculopathy. The creatine phosphokinase (CPK)-MM serum levels were measured on admission and at 1, 3, and 5 days postoperatively. Postoperative pain was evaluated using a 10-point visual analogue scale (VAS) and recorded on admission and at 1, 3, and 5 days postoperatively. The results were compared to those from the conventional subperiosteal microdiscectomy (43 patients). Results : The CPK-MM levels were significantly lower in the serum of the MSTM group compared to the CSM group on postoperative days three and five (p = 0.03 and p = 0.02, respectively). The clinical scales for back pain using VAS were significantly lower in the MSTM group than in the CSM group on postoperative days three (p = 0.04). The mean VAS scores for leg pain in both groups showed no significant differences during the early postoperative period. Conclusion : Muscle sparing transmuscular microdiscectomy is a minimally invasive surgical option to treat lumbar radiculopathy due to herniated disc. The approach affected minimal injury to posterior lumbar supporting structures with alleviated postoperative back pain.

• Journal of Chest Surgery
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• v.14 no.2
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• pp.144-152
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• 1981

The effect of cardiopulmonary bypass procedures on the blood components were studied through the measurements of several serum enzymes, SGOT, SGPT, CPK and LDH with its isozymes in the patients who had surgery for their heart diseases. They wre 85 patients: 40 Males and 45 Females. Their ages ranged widely between one and fifty-six. They were divided into 5 groups: Group I.patent ductus arteriosus without extracorporeal circulation, Group II-atrial septal defect, Group III-ventricular septal defect, Group IV-tetralogy of Fallot, and Group V-valve replacement. Generally serum enzymes revealed the increased values after surgery and the tendency returning toward preoperative levels. With the high total serum LDH levels seen uniformly after operation which persisted long in patients with replaced valves, the changes of LDH-isozymes were further analyzed. The isozymes, especially LDI and LDs increased their activities postoperatively, and the other fractions varied little. And $LD_1$/$LD_2$ ratios also showed similar rises and falls while the elevated values lasted longer in the patients with cardiac valve replacement. The significant values of LDH-isozymes in predicting the hemolysis occuring after extracorporeal circulation and in following the patients whose valves were replaced have been further discussed with the special stress placed on the $LD_1$/$LD_2$ratios.