• Journal of Oral Medicine and Pain
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• 제22권2호
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• pp.327-339
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• 1997

This study aimed at evaluating tile relationship between pressure pain threshold(PPT) and electromyographic(EMG) activity in 30 healthy volunteers and 30 patients with temporomandibular disorders. PPTs were determined with electric pressure algometry over masseter, temporalis anterior, sternocleidomastoid, and trapezius muscle during resting and clenching. To obtain more reliable result, two examiners measured PPTs two times on each muscles, randomly. Resting and clenching EMG activity and tenderness of all muscles were measured to evaluate the relationship with PPTs. The collected data were processed by SAS/STAT program. The obtained results were as follows : 1. Pressure pain thresholds in tendered muscles were lower than those in non-tendered muscles. This tendency was more prominant in masticatory muscles than in cervical muscles and in clenching than in resting. 2. There ware a tendency of higher PPTs in unaffected side than in affected side, but there were no significant difference statistically. 3. There wert no difference of PPTs between in preferred side and in ipsilateral side, significantly. 4. There was a significantly positive correlation between resting and clenching PPTs, but there were no correlation between PPTs and EMG activities. 5. Comparison of EMG activity between in higher group and in lower group by resting PPTs didn't show any significant difference. But resting EMG activity in the higher group of clenching PPTs were lower, on the contrary, clenching activity were higher than those in lower groups of clenching PPTs. From this results, the author concluded that the clenching PPTs was more important than resting PPTs in diagnosis of muscle dysfunction. And the author recommanded that all of three following test were performed for the proper diagnosis and treatment of orofacial Pain : muscle tenderness, EMG activity, and PPT.

• 한국태양에너지학회 논문집
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• 제30권5호
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• pp.107-114
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• 2010

Understanding of reflectance of solar concentrators is important for assessing concentration performance. However inaccurate data about refractive indices of constituent materials and dust accumulation on the surface often prevent figuring out reflectance variations. The current study proposes an approach calculating concentrator reflectance based on the refractive index of glass obtained from reflectance and transmittance measurements. This approach improved accuracy of solar-averaged reflectance from 2.9% to 0.4% compared to the use of existing reference data. Reflectance variations with incidence angles are negligible up to $60^{\circ}C$ at various glass thicknesses. When concentrators are contaminated with dust during 2 months specular reflectance loss of vertically exposed concentrators is less than 7%. However for horizontally exposed concentrators the loss significantly increases up to 40% while dependence of reflectance on incidence angles becomes strong. Measurements of hemispherical reflectance indicate that 80 percentage of the loss comes from scattering rather than absorption by dust. Data of refractive index and reflectance provided in the current study will help estimate or model the concentrated solar flux.

• Journal of Oral Medicine and Pain
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• 제21권2호
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• pp.265-277
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• 1996

The aim of this study was to investigate the electromyographic(EMG) activity of masticatory and cervical muscles according to chewing pattern in coronal plane during gum chewing. 70 patients with temporomandibular disorders and 30 dental students without any signs and symptoms of the disorders participated in this study. We measured the activity of masseter (MM), anterior temporalis(TA), sternocleidomastoideus(SCM) and trapezius muscle and recorded the chewing patterns using Biopak system synchronously. Chewing pattern was classified into S- or L-pattern by the midline opening path and short or long type by the lateral distance from midline. Obtained data were analyzed with SAS/STAT Program. The obtained results were as follows : 1. Generally, there was tended to be higher activity in the control group than in the patients group. 2. When comparing EMG activity according to preferred side, the muscle activity was tended to higher on the preferred chewing side than on the contralateral side. However, this difference is insignificant statistically 3. In unilateral affected patients, there was no difference in muscle activity between affected chewing side and unaffected chewing side except for the EMG of the temporalis anterior muscle. 4. Despite the varietal in each of the following variables, there mere no differences in EMG activity during gum chewing: chewing pattern in coronal plane and lateral distance of chewing. 5. The activity of SCM in chewing side was higher than that in contralateral side (p<0.001), but there was no difference in trapezius muscle. 6. In all of the control group, there was appeared L-chewing pattern than not involved the midline during preferred side chewing.

• Journal of Oral Medicine and Pain
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• 제21권2호
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• pp.383-392
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• 1996

An observation and evaluation of the reproducibility of the mandibular movements has been a integral part of a test for mandibular function and dysfunction. After Pantographic Reproducibility Index(PRI) was introduced in dentistry, many authors have used the index for investigation of mandibular movement function, especially in condylar compartment. Howerer, the difficult and time-consuming work of instrumentation for getting the PRI has been a major obstacle in using pantograph. This study was performed to try a new mandibular reproducibility index, so-called BioEGN reproducibility index(BERI), calculated from mandibular trajectory recorded with BioEGN. 26 dental students without any signs and symptoms of temporomandibular disorders and 22 patients with temporomandibular disorders took part in this study and classed to control group and patients group, respectively. Pantronic and BioEGN were used to record and calculate the indices, PRI and BERI. PRI had only one value, but BERI had two values of outgoing and incoming movement in each scale. With two scales of small and large, as a result, BERI had four values in this study. PRI corresponded to BERI in small scale on outgoing total movements. The data were calculated and analyzed with SAS/stat program and the conclusion of this study were as follows : 1. In every scales, in each movement, BERI on outgoing movement in control group was lower than that in patients group, respectively, but BERI on incoming movement was only different in one side movement, that was, left excursion. 2. The difference between BERI on outgoing movement and BERI on incoming movement was only shown in small scale on total movements, not in each movement, in control group. However, there was generally a positive correlationship between BERI on outgoing movement and BERI on incoming movement in each movement in both groups. 3. Simple statistics of PRI was similar to that of BERI on total movements in small scale, but there was a negative correlation between PRI and BERI on total movements in large sclae only in patients group.

• Journal of Oral Medicine and Pain
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• 제24권1호
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• pp.95-106
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• 1999

This study was performed to investigate the age distribution with tooth calcification and degree of eruption of permanent teeth. For the study, healthy 184 patients from 5 to 19 years old without any previous serious dental treatment were randomly selected, and intraoral standard films and dental casts were taken for evaluation of stage of calcification and degree of eruption, respectively. Tooth calcification of 13 stages, designed by the author based on the Nolla's classification and eruption level of 4 or 5 degree was used. Data were processed by SAS/Stat program and the obtained results were as follows; 1. The age of root completed with open apex in lower posterior teeth were 13.8 years for first premolar, 14.0 years for second premolar, 10.5 years for first molar, and 14.2 years for second molar. There were no significant difference between right and left side. 2. As for the sequence of eruption, first molar was the first teeth erupted in upper arch, while central incisor was the first teeth in lower arch. In general, eruption of lower teeth were slightly earlier than the corresponding teeth of upper arch. 3. There were no difference of age of the same stage of development between Nolla's and the author's classification. From the results, the author's classification can be used for estimation of age with more finely in age of 8 to 15 years old. 4. Multiple regression equations for age with Nolla's(Ns) and the author's(Ks) classification of tooth calcification, and degree of eruption(DE) were as follow; Age(by #34) = 7.55 + 0.76Ks34 + 0.80DE34 - 0.72Ns34 Age(by #35) = 7.10 + 0.81Ks35 + 0.6IDE35 Age(by #37) = 6.61 + 0.82Ks37 + 0.5IDE37. Age(by #44) = 7.02 + 0.62Ks44 + 0.82DE44 Age(by #45) = 8.04 + 0.93Ks45 + 0.64DE45 - 0.89Ns45 Age(by #47) = 6.40 + 0.86Ks47 + 0.56DE47.

• Journal of Microbiology and Biotechnology
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• 제14권2호
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• pp.225-230
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• 2004

A plasminogen kringle domain 1 to 3, rKl-3, was expressed in Escherichia coli under the control of T7 promoter. For the cost-effective production of rKl-3, the induction process was analyzed and optimized. Induction characteristics with lactose were analyzed in terms of induction time and inducer concentration in various culture conditions including batch and high-cell-density fed-batch cultures. In the fed-batch culture, the induction around 6 h after initiation of the DO-stat fed-batch culture resulted in the highest expression level of rKI-3 among the induction points examined. The highest demand of oxygen at this point was crucial for the maximum expression level of rKI-3. As the lactose concentration increased, the expression level also increased, though the expression level showed a plateau above a concentration of 14 mM of lactose. Lactose acted less specifically than IPTG since most of it was hydrolyzed to glucose and galactose. However, using lactose, the cell growth and the maximum expression level of rKl-3 increased by 20% and 24%, respectively, compared with those using IPTG in the fed-batch culture. The lactose seemed to be hydrolyzed by intracellular and extracellular $\beta$-galactosidase liberated by cell lysis at the same time. Residual concentration of glucose was maintained to a a limit of detection by high performance liquid chromatography, and galactose was not consumed by the host strain Escherichia coli BL2l(DE3).

• 한국동물위생학회지
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• 제30권3호
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• pp.375-384
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• 2007

This study was conducted to investigate the characteristics of brucellosis in Korean native cattle in a farm where bovine brucellosis was confirmed 3 times from September 2006 to March 2007. Of 74 bulls serum samples examined, 21 (28.4%) were positive by Rose-Bengal test (RBT) and Standard tube agglutination test (STAT). In the isolation test from seropositive bulls, B abortus was isolated and identified from 2 specimens (testis, intestinal lymph node) among 6 kinds of specimens including blood, urine, feces and soil. Isolation rate of intestinal lymph node and testis was 25% (3/12 cases) and 16.7% (2/12), respectively. B abortus was also isolated from calves below 12 months old, i.e., 1 isolate (25.0%) was confirmed from testis, 4 (40.0%) from supra-mammary lymph nodes and 1 (25.0%) from intestinal lymph node. All isolates had Brucella specific 16s r-RNA with 905-bp band detected by PCR assay. For the more effective control of bovine brucellosis in korea, this paper would like to suggest that all of bulls and calves should be included in the screening tests.

• Toxicological Research
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• 제28권4호
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• pp.255-262
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• 2012

Inflammation is the immune system's response to infection and injury-related disorders, and is related to pro-inflammatory factors (NO, $PGE_2$, cytokines, etc.) produced by inflammatory cells. Atopic dermatitis (AD) is a representative inflammatory skin disease that is characterized by increasing serum levels of inflammatory chemokines, including macrophage-derived chemokine (MDC). Carpinus tschonoskii is a member of the genus Carpinus. We investigated the anti-inflammatory activity of C. tschonoskii by studying the effects of various solvent fractions prepared from its leaves on inflammatory mediators in HaCaT and RAW264.7 cells. We found that the chloroform fraction of C. tschonoskii inhibited MDC at both the protein and mRNA levels in HaCaT cells, acting via the inhibition of STAT1 in the IFN-${\gamma}$ signaling pathway. In addition, the chloroform fraction significantly suppressed the expression of inflammatory factors induced by lipopolysaccharide stimulation, except COX-2 and TNF-${\alpha}$. These results suggest that the chloroform fraction of C. tschonoskii leaves may include a component with potential anti-inflammatory activity.

• Toxicological Research
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• 제33권4호
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• pp.325-332
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• 2017

3-Bromo-4,5-dihydroxybenzaldehyde (BDB) is a natural bromophenol compound that is most commonly isolated from red algae. The present study was designed to investigate the anti-inflammatory properties of BDB on atopic dermatitis (AD) in mice induced by 2,4-dinitrochlorobenzene (DNCB) and on lipopolysaccharide (LPS)-stimulated murine macrophages. BDB treatment (100 mg/kg) resulted in suppression of the development of AD symptoms compared with the control treatment (induction-only), as demonstrated by reduced immunoglobulin E levels in serum, smaller lymph nodes with reduced thickness and length, a decrease in ear edema, and reduced levels of inflammatory cell infiltration in the ears. In RAW 264.7 murine macrophages, BDB (12.5, 25, 50, and $100{\mu}M$) suppressed the production of interleukin-6, a proinflammatory cytokine, in a dose-dependent manner. BDB also had an inhibitory effect on the phosphorylation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-${\kappa}B$) and signal transducer and activator of transcription 1 (STAT1; Tyr 701), two major signaling molecules involved in cellular inflammation. Taken together, the results show that BDB treatment alleviates inflammatory responses in an atopic dermatitis mouse model and RAW 264.7 macrophages. These results suggest that BDB may be a useful therapeutic strategy for treating conditions involving allergic inflammation such as atopic dermatitis.

• 한국정보통신학회논문지
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• 제12권11호
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• pp.1923-1932
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• 2008

무인 운반설비의 자동화 시스템 개발의 한 부분으로써 여러 Vision 센서 중 레이저 센서를 이용하여 작업 공간상에 있는 판재류와 코일류의 경계부분을 인식한다. 다음으로 인식한 물체의 경계를 이용하여 3차원 공간상의 위치 좌표를 추출하여 무인크레인에 이동해야할 위치 좌표를 전달한다. 본 연구에서는, 첫 번째 레이저 센서를 이용한 물체의 경계 추출, 두 번째 레이저 센서의 z축 기울기 각 추출, 세 번째 인식한 경계를 이용하여 물체의 2차원 위치좌표 추출, 네 번째 레이저 센서를 이용하여 판재와 코일의 판별, 다섯 번째 물체 판별의 결과에 따른 판재 와 코일의 3차원 위치좌표 추출을 목적으로 한다. 본 연구의 결과는 무인 운반설비의 자동화 시스템 개발에 상당한 도움이 될 것으로 기대된다.