The Chloroform Fraction of Carpinus tschonoskii Leaves Inhibits the Production of Inflammatory Mediators in HaCaT Keratinocytes and RAW264.7 Macrophages |
Kang, Gyeoung-Jin
(Department of Pharmacology, School of Medicine, Jeju National University)
Kang, Na-Jin (Department of Biomedicine & Drug Development, Jeju National University) Han, Sang-Chul (Department of Pharmacology, School of Medicine, Jeju National University) Koo, Dong-Hwan (Department of Biomedicine & Drug Development, Jeju National University) Kang, Hee-Kyoung (Department of Pharmacology, School of Medicine, Jeju National University) Yoo, Byoung-Sam (Cosmetic R&D Center, COSMAX Inc.) Yoo, Eun-Sook (Department of Pharmacology, School of Medicine, Jeju National University) |
1 | Ulevitch, R.J., Mathison, J.C. and da Silva Correia, J. (2004). Innate immune responses during infection. Vaccine, 22 Suppl 1, S25-S30. DOI ScienceOn |
2 | van Boxel-Dezaire, A.H. and Stark, G.R. (2007). Cell type-specific signaling in response to interferon-gamma. Curr. Top. Microbiol. Immunol., 316, 119-154. DOI |
3 | Yamada, P., Ono, T., Shigemori, H., Han, J. and Isoda, H. (2012). Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells. Cytotechnology, 64, 349-356. DOI ScienceOn |
4 |
Zhang, R., Kang, K.A., Piao, M.J., Park, J.W., Shin, T., Yoo, B.S., Yang, Y.T. and Hyun, J.W. (2007). Cytoprotective activity of Carpinus tschonoskii against |
5 | Coleman, J.W. (2001). Nitric oxide in immunity and inflammation. Int. Immunopharmacol., 1, 1397-1406. DOI ScienceOn |
6 | Damte, D., Reza, M.A., Lee, S.J., Jo, W.S. and Park, S.C. (2011). Anti-inflammatory activity of dichloromethane extract of auricularia auricula-judae in RAW264.7 cells. Toxicol. Res., 27, 11-14. DOI ScienceOn |
7 | Duffield, J.S. (2003). The inflammatory macrophage: a story of Jekyll and Hyde. Clin. Sci. (Lond), 104, 27-38. DOI ScienceOn |
8 | Gough, D.J., Levy, D.E., Johnstone, R.W. and Clarke, C.J. (2008). IFNgamma signaling-does it mean JAK-STAT? Cytokine Growth Factor Rev., 19, 383-394. DOI ScienceOn |
9 | Hammer, K.D., Yum, M.Y., Dixon, P.M. and Birt, D.F. (2010). Identification of JAK-STAT pathways as important for the antiinflammatory activity of a Hypericum perforatum fraction and bioactive constituents in RAW 264.7 mouse macrophages. Phytochemistry, 71, 716-725. DOI ScienceOn |
10 | Hongqin, T., Xinyu, L., Heng, G., Lanfang, X., Yongfang, W. and Shasha, S. (2011). Triptolide inhibits IFN-gamma signaling via the Jak/STAT pathway in HaCaT keratinocytes. Phytother. Res., 25, 1678-1685. DOI ScienceOn |
11 | Hu, X., Chen, J., Wang, L. and Ivashkiv, L.B. (2007). Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J. Leukocyte Biol., 82, 237-243. DOI ScienceOn |
12 | Jeon, J.I. and Chang, C.S. (2000). Foliar flavonoids of genus carpinus in eastern Asia. Kor. J. Plant Tax., 30, 139-153. |
13 | Jeong, S.I., Choi, B.M. and Jang, S.I. (2010). Sulforaphane suppresses TARC/CCL17 and MDC/CCL22 expression through heme oxygenase-1 and NF-kappaB in human keratinocytes. Arch. Pharm. Res., 33, 1867-1876. DOI ScienceOn |
14 | Ju, S.M., Song, H.Y., Lee, S.J., Seo, W.Y., Sin, D.H., Goh, A.R., Kang, Y.H., Kang, I.J., Won, M.H., Yi, J.S., Kwon, D.J., Bae, Y.S., Choi, S.Y. and Park, J. (2009). Suppression of thymusand activation-regulated chemokine (TARC/CCL17) production by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose via blockade of NF-kappaB and STAT1 activation in the HaCaT cells. Biochem. Biophys. Res. Commun., 387, 115-120. DOI ScienceOn |
15 | Kakinuma, T., Nakamura, K., Wakugawa, M., Mitsui, H., Tada, Y., Saeki, H., Torii, H., Komine, M., Asahina, A. and Tamaki, K. (2002). Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis. Clin. Exp. Immunol., 127, 270-273. DOI |
16 | Kang, G.J., Han, S.C., Yi, E.J., Kang, H.K. and Yoo, E.S. (2011). The inhibitory effect of premature Citrus unshiu extract on atopic dermatitis in vitro and in vivo. Toxicol. Res., 27, 173-180. DOI ScienceOn |
17 | Kaplan, A.P. (2001). Chemokines, chemokine receptors and allergy. Int. Arch. Allergy Immunol., 124, 423-431. DOI ScienceOn |
18 | Koo, J.E., Hong, H.J., Mathema, V.B., Kang, H.K., Hyun, J.W., Kim, G.Y., Kim, Y.R., Maeng, Y.H., Hyun, C.L., Chang, W.Y. and Koh, Y.S. (2012). Inhibitory effects of Carpinus tschonoskii leaves extract on CpG-stimulated pro-inflammatory cytokine production in murine bone marrow-derived macrophages and dendritic cells. In Vitro Cell. Dev. Biol. Anim., 48, 197-202. DOI ScienceOn |
19 | Lee, H.J., Dang, H.T., Kang, G.J., Yang, E.J., Park, S.S., Yoon, W.J., Jung, J.H., Kang, H.K. and Yoo, E.S. (2009). Two enone fatty acids isolated from Gracilaria verrucosa suppress the production of inflammatory mediators by down-regulating NFkappaB and STAT1 activity in lipopolysaccharide-stimulated RAW 264.7 cells. Arch. Pharm. Res., 32, 453-462. DOI ScienceOn |
20 | Leung, T.F., Ma, K.C., Hon, K.L., Lam, C.W., Wan, H., Li, C.Y. and Chan, I.H. (2003). Serum concentration of macrophagederived chemokine may be a useful inflammatory marker for assessing severity of atopic dermatitis in infants and young children. Pediatr. Allergy Immunol., 14, 296-301. DOI ScienceOn |
21 | Li, C.C., Hsiang, C.Y., Lo, H.Y., Pai, F.T., Wu, S.L. and Ho, T.Y. (2012). Genipin inhibits lipopolysaccharide-induced acute systemic inflammation in mice as evidenced by nuclear factor-kappaB bioluminescent imaging-guided transcriptomic analysis. Food Chem. Toxicol., 50, 2978-2986. DOI ScienceOn |
22 | Luster, A.D. (2001). Antichemokine immunotherapy for allergic diseases. Curr. Opin. Allergy Clin. Immunol., 1, 561-567. DOI |
23 | MacMicking, J.D., Nathan, C., Hom, G., Chartrain, N., Fletcher, D.S., Trumbauer, M., Stevens, K., Xie, Q.W., Sokol, K. and Hutchinson, N. (1995). Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell., 81, 641-650. DOI ScienceOn |
24 | Mantovani, A., Gray, P.A., Van Damme, J. and Sozzani, S. (2000). Macrophage-derived chemokine (MDC). J. Leukocyte Biol., 68, 400-404. |
25 | Marcuzzi, A., Secchiero, P., Crovella, S. and Zauli, G. (2012). TRAIL administration down-modulated the acute systemic inflammatory response induced in a mouse model by muramyldipeptide or lipopolysaccharide. Cytokine, 60, 43-46. DOI ScienceOn |
26 | Maruotti, N., Cantatore, F.P., Crivellato, E., Vacca, A. and Ribatti, D. (2007). Macrophages in rheumatoid arthritis. Histol. Histopathol., 22, 581-586. |
27 | Michelsen, K.S., Doherty, T.M., Shah, P.K. and Arditi, M. (2004). TLR signaling: an emerging bridge from innate immunity to atherogenesis. J. Immunol., 173, 5901-5907. DOI |
28 | Palsson-McDermott, E.M. and O'Neill, L.A. (2004). Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunol., 113, 153-162. DOI ScienceOn |
29 | Pease, J.E. and Williams, T.J. (2006). Chemokines and their receptors in allergic disease. J. Allergy Clin. Immunol., 118, 305-318. DOI ScienceOn |
30 | Ricciotti, E. and FitzGerald, G.A. (2011). Prostaglandins and inflammation. Arterioscler. Thromb. Vasc. Biol., 31, 986-1000. DOI ScienceOn |
31 | Stempelj, M., Kedinger, M., Augenlicht, L. and Klampfer, L. (2007). Essential role of the JAK/STAT1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate. J. Biol. Chem., 282, 9797-9804. DOI ScienceOn |
32 | Takeshita, F., Gursel, I., Ishii, K.J., Suzuki, K., Gursel, M. and Klinman, D.M. (2004). Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9. Semin. Immunol., 16, 17-22. DOI ScienceOn |
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