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Improvement of Antifungal Activity of for Water-Dispersed Cosmetic Formulations (수분산 제형의 화장품에 대한 항진균력 향상)

  • Lee, Ye Ji;Seo, Jae Yong;Yang, Hyeon Gap;Lee, Ju kyeong;Baek, Sol Bee;Cho, Hyun Dae;Jeong, Noh Hee
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.2
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    • pp.135-146
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    • 2022
  • In order to prevent microbial contamination and safely use cosmetics, it is essential to possess preservative power. In this study, the antifungal effect was confirmed by improving the preservative system of the aqueous dispersion formulation, which has a weak preservative power against fungi, and various preservative systems were established to strengthen the preservative power against fungi. Five kinds of raw materials (sodium anisate, p-anisic acid, caprylhydroxamic acid, o-cymen-5-ol, hydroxyacetophenone) that have a benzene ring structure having a hydroxyl group and exist as protonated form in cosmetic formulations expected to improve antifungal activity in cosmetics were selected, and the minimum growth inhibitory concentration of the raw materials was determined through MIC assay. It was confirmed that the preservative power against mold was improved through the preservative efficacy test of 4 types of water dispersion formulations (cream, lotion, toner, and sun cream) in which 4 types of raw materials showing antimicrobial activity against mold were added to the preservative system. When p-anisic acid was used, it was confirmed that the preservative activity against mold was strengthened without the effect of inhibiting the preservative power against bacteria and yeast in all four formulations.

Experimental analysis and modeling for predicting bistatic reverberation in the presence of artificial bubbles (인공기포 존재 환경에서의 양상태 잔향음 예측을 위한 해상 실험 분석 및 모델링 연구)

  • Yang, Wonjun;Oh, Raegeun;Bae, Ho Seuk;Son, Su-Uk;Kim, Da Sol;Choi, Jee Woong
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.4
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    • pp.426-434
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    • 2022
  • Bubbles generated by various causes in the ocean are known to persist for long periods of time. Although the volume occupied by bubbles in the ocean is small, the presence of bubbles in ocean due to resonance and attenuation greatly affects the acoustic properties. Accordingly, bistatic reverberation experiment was performed in the ocean where artificial bubbles exist. A number of transducers and receivers were installed on 6 buoys arranged in a hexagonal shape, and blowing agents were dropped in the center of the buoy to generate bubbles. For reverberation modeling that reflects acoustic characteristics changed by bubbles, the spatial distribution of bubbles was estimated using video data and received signals. A measurement-based bubble spectral shape was used, and it was assumed that the bubble density within the spatial distribution of the estimated bubble was the same. As a result, it was confirmed that the bubble reverberation was simulated in a time similar to the measured data regardless of the bubble density, and the bubble reverberation level similar to the measured data was simulated at a void fraction of about 10-7 ~ 10-6.8.

Structural and Electrical Properties of La0.7Sr0.3MnO3 Thin Films for Thermistor Applications (서미스터로의 응용을 위한 La0.7Sr0.3MnO3 박막의 구조적, 전기적 특성)

  • Lim, Jeong-Eun;Park, Byeong-Jun;Yi, Sam-Haeng;Lee, Myung-Gyu;Park, Joo-Seok;Kim, Byung-Cheul;Kim, Young-Gon;Lee, Sung-Gap
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.5
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    • pp.499-503
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    • 2022
  • La0.7Sr0.3MnO3 precursor solution were prepared by a sol-gel method. La0.7Sr0.3MnO3 thin films were fabricated by a spin-coating method on a Pt/Ti/SiO2/Si substrate. Structural and electrical properties with the variation of sintering temperature were measured. All specimens exhibited a polycrystalline orthorhombic crystal structure, and the average thickness of the specimens coated 6 times decreased from about 427 nm to 383 nm as the sintering temperature increased from 740℃ to 830℃. Electrical resistance decreased as the sintering temperature increased. In the La0.7Sr0.3MnO3 thin films sintered at 830℃, electrical resistivity, TCR, B-value, and activation energy were 0.0374 mΩ·cm, 0.316%/℃, 296 K and 0.023 eV, respectively.

Whitening and inhibiting NF-κB-mediated inflammation properties of the biotransformed green ginseng berry of new cultivar K1, ginsenoside Rg2 enriched, on B16 and LPS-stimulated RAW 264.7 cells

  • Xu, Xing Yue;Yi, Eun Seob;Kang, Chang Ho;Liu, Ying;Lee, Yeong-Geun;Choi, Han Sol;Jang, Hyun Bin;Huo, Yue;Baek, Nam-In;Yang, Deok Chun;Kim, Yeon-Ju
    • Journal of Ginseng Research
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    • v.45 no.6
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    • pp.631-641
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    • 2021
  • Background: Main bioactive constituents and pharmacological functions of ripened red ginseng berry (Panax ginseng Meyer) have been frequently reported. Yet, the research gap targeting the beneficial activities of transformed green ginseng berries has not reported elsewhere. Methods: Ginsenosides of new green berry cultivar K-1 (GK-1) were identified by HPLC-QTOF/MS. Ginsenosides bioconversion in GK-1 by bgp1 enzyme was confirmed with HPLC and TLC. Then, mechanisms of GK-1 and β-glucosidase (bgp1) biotransformed GK-1 (BGK-1) were determined by Quantitative Reverse Transcription-Polymerase Chain Reaction and Western blot. Results: GK-1 possesses highest ginsenosides especially ginsenoside-Re amongst seven ginseng cultivars including (Chunpoong, Huangsuk, Kumpoong, K-1, Honkaejong, Gopoong, and Yunpoong). Ginseng root's biomass is not affected with the harvest of GK-1 at 3 weeks after flowering period. Then, Re is bioconverted into a promising pharmaceutical effect of Rg2 via bgp1. According to the results of cell assays, BGK-1 shows decrease of tyrosinase and melanin content in α-melanocyte-stimulating hormone challenged-murine melanoma B16 cells. BGK-1 which is comparatively more effective than GK-1 extract shows significant suppression of the nuclear factor (NF)-κB activation and inflammatory target genes, in LPS-stimulated RAW 264.7 cells. Conclusion: These results reported effective whitening and anti-inflammatory of BGK-1 as compared to GK-1.

Analysis of Time Series Changes in the Surrounding Environment of Rural Local Resources Using Aerial Photography and UAV - Focousing on Gyeolseong-myeon, Hongseong-gun - (항공사진과 UAV를 이용한 농촌지역자원 주변환경의 시계열 변화 분석 - 충청남도 홍성군 결성면을 중심으로 -)

  • An, Phil-Gyun;Eom, Seong-Jun;Kim, Yong-Gyun;Cho, Han-Sol;Kim, Sang-Bum
    • Journal of Korean Society of Rural Planning
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    • v.27 no.4
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    • pp.55-70
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    • 2021
  • In this study, in the field of remote sensing, where the scope of application is rapidly expanding to fields such as land monitoring, disaster prediction, facility safety inspection, and maintenance of cultural properties, monitoring of rural space and surrounding environment using UAV is utilized. It was carried out to verify the possibility, and the following main results were derived. First, the aerial image taken with an unmanned aerial vehicle had a much higher image size and spatial resolution than the aerial image provided by the National Geographic Information Service. It was suitable for analysis due to its high accuracy. Second, the more the number of photographed photos and the more complex the terrain features, the more the point cloud included in the aerial image taken with the UAV was extracted. As the amount of point cloud increases, accurate 3D mapping is possible, For accurate 3D mapping, it is judged that a point cloud acquisition method for difficult-to-photograph parts in the air is required. Third, 3D mapping technology using point cloud is effective for monitoring rural space and rural resources because it enables observation and comparison of parts that cannot be read from general aerial images. Fourth, the digital elevation model(DEM) produced with aerial image taken with an UAV can visually express the altitude and shape of the topography of the study site, so it can be used as data to predict the effects of topographical changes due to changes in rural space. Therefore, it is possible to utilize various results using the data included in the aerial image taken by the UAV. In this study, the superiority of images acquired by UAV was verified by comparison with existing images, and the effect of 3D mapping on rural space monitoring was visually analyzed. If various types of spatial data such as GIS analysis and topographic map production are collected and utilized using data that can be acquired by unmanned aerial vehicles, it is expected to be used as basic data for rural planning to maintain and preserve the rural environment.

An autoethnography on the Development and counseling Experience of Non-face-to-face Mental Health Mobile Service Platform of Mental Health Social Welfare expert (정신건강사회복지 전문가의 비대면 정신건강 모바일 서비스 플랫폼 개발 및 상담 경험에 관한 자문화기술지)

  • Lee, Sol-Ji
    • Journal of Internet of Things and Convergence
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    • v.8 no.5
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    • pp.63-70
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    • 2022
  • This study is a study that collects and analyzes data through An autoethnographyon as one of method of qualitative research, through which researcher have experienced firsthand in the process of developmenting and counseling there a new concept professional mental health mobile service platform as a mental health social welfare expert. The results of this study are as follows.First, there are people in Korea who are directly exposed to mental health issues and need to receive professional medical services, but there are also quite a few members of the public who have a desire for general mental health services, although the level of therapeutic intervention is not required. Second, considering the characteristics of modern society and especially in the pandemic situation of infectious diseases such as COVID-19, more and more people are preferring various mental health service platforms using mobile devices. Third, all generations complain of mental health issues such as family problems, stress, interpersonal relationships, and occupations, and other mental health problems such as self-harm and suicide accidents are frequently mentioned in connection with mental disorders such as depression, anxiety disorder, addiction, and post-traumatic stress disorder. Fourth, youngth s were exposed to various mental health-related issues, and above all, they were complaining of serious mental health problems such as self-harm and suicide accidents. Fifth, in delivering professional mental health services, mental health experts with the ability also to provide professional services online through mobile devices are needed as well offline. Finally, based on the results of this study, policy and practical suggestions related to the provision of mental health services in the future, and directions for follow-up studies were suggested.

Synthesis of Sludge Waste-derived Semiconductor Grade Uniform Colloidal Silica Nanoparticles and Their CMP Application (슬러지 폐기물을 활용한 반도체급 균일한 콜로이달 실리카 나노입자의 제조 및 CMP 응용)

  • Kim, Dong Hyun;Kim, Jiwon;Jekal, Suk;Kim, Min Jeong;Kim, Ha-Yeong;Kim, Min Sang;Kim, Sang-Chun;Park, Seon-Young;Yoon, Chang-Min
    • Journal of the Korea Organic Resources Recycling Association
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    • v.30 no.3
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    • pp.5-12
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    • 2022
  • This study suggests the effective recycling method of sludge waste from various industrial fields to synthesize uniform colloidal silica nanoparticles. In detail, polymers are removed from the sludge waste to attain sludge-extracted silica (s-SiO2) micron-sized particles, and ammonia assisted sonication is applied to s-SiO2, which has effectively extracted the silanol precursor. The nano-sized silica (n-SiO2) particles are successfully synthesized by a typical sol-gel method using silanol precursor. Also, the yield amounts of n-SiO2 are determined by the function of s-SiO2 etching time. Finally, n-SiO2-based slurry is synthesized for the practical CMP application. As a result, rough-surfaced semiconductor chip is successfully polished by the n-SiO2-based slurry to exhibit the mirror-like clean surface. In this regard, sludge wastes are successfully prepared as valuable semicondutor grade materials.

Spatio-spectral Fusion of Multi-sensor Satellite Images Based on Area-to-point Regression Kriging: An Experiment on the Generation of High Spatial Resolution Red-edge and Short-wave Infrared Bands (영역-점 회귀 크리깅 기반 다중센서 위성영상의 공간-분광 융합: 고해상도 적색 경계 및 단파 적외선 밴드 생성 실험)

  • Park, Soyeon;Kang, Sol A;Park, No-Wook
    • Korean Journal of Remote Sensing
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    • v.38 no.5_1
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    • pp.523-533
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    • 2022
  • This paper presents a two-stage spatio-spectral fusion method (2SSFM) based on area-to-point regression kriging (ATPRK) to enhance spatial and spectral resolutions using multi-sensor satellite images with complementary spatial and spectral resolutions. 2SSFM combines ATPRK and random forest regression to predict spectral bands at high spatial resolution from multi-sensor satellite images. In the first stage, ATPRK-based spatial down scaling is performed to reduce the differences in spatial resolution between multi-sensor satellite images. In the second stage, regression modeling using random forest is then applied to quantify the relationship of spectral bands between multi-sensor satellite images. The prediction performance of 2SSFM was evaluated through a case study of the generation of red-edge and short-wave infrared bands. The red-edge and short-wave infrared bands of PlanetScope images were predicted from Sentinel-2 images using 2SSFM. From the case study, 2SSFM could generate red-edge and short-wave infrared bands with improved spatial resolution and similar spectral patterns to the actual spectral bands, which confirms the feasibility of 2SSFM for the generation of spectral bands not provided in high spatial resolution satellite images. Thus, 2SSFM can be applied to generate various spectral indices using the predicted spectral bands that are actually unavailable but effective for environmental monitoring.

Impact of Renewable Energy on Extension of Vaccine Cold-chain: a case study in Nepal (신재생 에너지의 백신 콜드체인 확장 효과: 네팔 사례 연구)

  • Kim, Min-Soo;Mun, Jeong-Wook;Yu, Jongha;Kim, Min-Sik;Bhandari, Binayak;Bak, Jeongeun;Bhattachan, Anuj;Mogasale, Vittal;Chu, Won-Shik;Lee, Caroline Sunyong;Song, Chulki;Ahn, Sung-Hoon
    • Journal of Appropriate Technology
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    • v.6 no.2
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    • pp.94-102
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    • 2020
  • Renewable energy (RE) is essential to comprise sustainable societies, especially, in rural villages of developing countries. Furthermore, application of off-grid RE systems to health care can improve the quality of life. In this research, a RE-based vaccination supply management system was constructed to enlarge the cold-chain in developing countries for the safe storage and delivery of vaccines. The system was comprised of the construction of RE plants and development of vaccine carriers. RE plants were constructed and connected to health posts in local villages. The cooling mechanism of vaccine carriers was improved and monitoring devices were installed. The effect of the system on vaccine cold-chain was evaluated from the field test and topographical analysis in the southern village of Nepal. RE plants were normally operated for the vaccine refrigerator in the health post. The modified vaccine carriers had a longer operation time and better temperature control via monitoring and RE-based recharging functionality. The topographical analysis estimated that the system can cover larger region. The system prototype showed great potential regarding the possibility of a sustainable and enlarged cold-chain. Thus, RE-based vaccine supply management is expected to facilitate vaccine availability while minimizing waste in the supply chain.

Can Traditional Industry Firms Be Born Global? Case Study with a Focus on Chinese and Korean Firms

  • Kang, Qingsong;Yoon, Ki-Chang;Park, Joshua
    • Journal of Korea Trade
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    • v.24 no.6
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    • pp.135-156
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    • 2020
  • Purpose - This study investigates whether the internationalization process of traditional industry firms can be categorized as born global, early internationalization, or gradual internationalization, and examines what factors promote internationalization in traditional industries using a case study of two firms, one each in China and Korea. Design/methodology - This study elects to use case study methodology to determine the "how" and "why" of internationalization process of traditional industry firms. Taking into consideration that factors that impact the internationalization process of firms are diverse and unclear in terms of causality, this study utilizes exploratory case study methodology. This research performs a comparative two-case study of two firms in traditional industries, one each in China and Korea, to examine similarities and differences of study subjects in order to improve the validity and suitability of research results. Findings - The findings of this research are as follows: First, traditional industries are more likely go through early and rapid internationalization rather than being born global; born globals are far more likely to appear in high tech industries. Second, the internationalization process of companies that go through early and rapid internationalization differs from what is indicated by traditional internationalization theories, and are not limited by factors like psychological distance and lack of experiential knowledge. Third, international entrepreneurship, international market orientation, and imitation and learning are important internal driving factors for early and rapid internationalization. Fourth, conditions within the domestic market, policy support from the government, and pilot effect from industry leaders are external driving factors for early and rapid internationalization. Originality/value - This study shows that the internationalization process of traditional industry firms is more likely to be early and rapid internationalization rather than being born global and suggests answers to why this may be the case. In addition, through an examination of case studies, it reveals that the internationalization process of traditional industry firms that undergo early and rapid internationalization is different from traditional internationalization theory, in that they are not limited by the lack of psychological proximity and empirical knowledge, and are driven by international entrepreneurship, international market orientation, imitation and learning, competitive pressure within the domestic market, government's policy support, and the pilot effect of industry leaders. Therefore, this study contributes to literature by expanding the scope of application of born global theory to traditional industries, making born global theory more generalizable and identifying driving factors to internationalization of traditional industry firms.