• Biomolecules & Therapeutics
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• 제20권2호
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• pp.234-238
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• 2012

Propofol is an anesthetic commonly used to provide sedation or to induce and maintain an anesthetic stated. However, there are reports which indicate propofol may cause psychological dependence or be abused. In the present study, we used various behavioral tests including climbing test, jumping test, conditioned place preference, and self-administration test to assess the dependence potential and abuse liability of propofol compared to a positive control (methamphetamine) or a negative control (saline or intralipid). Among the tests, the conditioned place preference test was conducted with a biased method, and the selfadministration test was performed under a fixed ratio (FR) 1 schedule, 1 h per session. No difference was found in the climbing test and jumping test, but propofol (30 mg/kg, i.p.) increased the rewarding effect in the conditioned place preference test, and it showed a positive reinforcing effect compared to the vehicle. These results indicate that propofol tends to show psychological dependence rather than physical dependence, and it seems not to be related with dopaminergic system.

• 한국구조물진단유지관리공학회 논문집
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• 제18권1호
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• pp.48-58
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• 2014

본 연구에서는 1992년 도로교설계기준의 내진설계도입 이전 규정에 따라 설계, 시공된 교각의 축소 모델을 실험체로 제작하여 원형기둥의 변위비에 따른 횡하중을 변위제어 방식으로 입력하여 준정적 방법을 통해 실험을 실시하였다. 연구에 적용한 보강재는 성능을 향상시킨 무기계 합금강인 Helical Bar로써 원형기둥 외부에 보강 후 실내실험을 통하여 파괴거동, 하중-변위 관계, 연성도 평가 및 에너지 평가를 실시하였다. 실험변수로는 위험단면 내에서 나선으로 보강한 보강재의 단면력의 크기와 나선보강의 간격, 보강형태로 두었으며, 준정적 실험을 통해 보강성능의 차이와 효과를 확인하였다. 실험결과 보강대상 부재의 성능에 따라 적절한 보강재의 단면력 크기결정과 보강간격 및 형식의 선정이 필요하며 기계적 보강재뿐만 아니라 고강도 콘크리트 피복으로의 치환으로도 보강성능이 향상됨을 확인할 수 있었다.

• 한방재활의학과학회지
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• 제19권2호
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• pp.113-123
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• 2009

Objectives : The purpose of this study is what Saamchimbeop's method of reinforcement and reduction. Methods : 1. We reffered to the Bo-Sa method of DongeuiBo-gam(東醫寶鑑), Uihakim-mun(醫學入門), Uihakjeong-jeon(醫學正傳), Chimgugyeongheom-bang(鍼灸經驗方), Biaoyou-fu(標幽賦) in Cimgudaeseong(鍼灸大成), Nei-Jing(內經). 2. We make a conjecture that Zheng(正), Ying(迎), Sui(隨), Xie(斜) Yingzheng(迎正), Duo(奪), Zhenghuoxie(正或斜), Wen(溫), Liang(凉), JongYang-Inyin (從陽引陰) in Saamchimbeop are another expression of method of reinforcement and reduction and compared with the method of reinforcement and reduction of DongeuiBo-gam(東醫寶鑑), Uihakim-mun(醫學入門), Uihakjeong-jeon(醫學正傳), Chimgugyeongheom-bang(鍼灸經驗方), Biaoyou-fu(標幽賦) in Cimgudaeseong(鍼灸大成), Nei-Jing(內經). Results : 1. Zheng(正) and Xie(斜) are angle of acupuncture manipulation. The descending inserting of Yang-meridian is acupuncture manipulation for the Tonifying effect(補法) and the direct inserting of Yin-meridian is the Dispersing effect(瀉法). 2. JongYang-Inyin(從陽引陰) is the contralateral acupuncture. 3. Ying(迎) and Sui(隨) in the Saamchimbeop are same meaning the method of reinforcement and reduction(補瀉手技法). 4. Saamchimbeop's the final aim is the Wen-Liang(溫凉) according to the disease strong and weak in the Ohaeng-seo of Saam-acupuncture. Conclusions : Saamchimbeop's method of reinforcement and reduction is reinforcement-reduction by lifting and thrusting the needle, breathing reinforcement-reduction method, reinforcing and reducing achieved by rapid and slow insertion and withdrawing of the needles, reinforcement and reduction by opening and closing of needles with contralateral acupuncture by Yin-meridian or Yang-meridian. Saamchimbeop's the final aim is the Wen-Liang(溫凉) according to the disease strong and weak.

• 대한치과보철학회지
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• 제34권4호
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• pp.823-832
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• 1996

The purpose of this study was to assess the effect of 1) the diameter(0.7,1.0,1.2mm) and number(1,2,3) of commonly available orthodontic metal wires embedded in self-curing orthodontic acrylic resin specimens($64{\times}10{\times}3mm$) and 2) the use of chemical adhesive system(Silicoater, Metalprimer) to prevent slipping at the interface between the resin and the metal wire on reinforcement by using three-point bending test. From this study, the following results were obtained. 1. No statistically significant difference was found among the transverse strengths for the control without reinforcement, one 0.7mm wire, two 0.7mm wires, three 0.7mm wires, and one 1.0mm wire groups(P>.05). 2. In the groups with 1.0 or 1.2mm wires, the transverse strength increased in proportion to the increase of number of wires(P<.05). 3. In the groups with 0.7 or 1.0mm wires, neither of Silicoater and Netalprimer increased the transverse strength significantly(P>.05). 4. No statistically significant difference was found in transverse strength between Silicoater groups and Metalprimer groups with same diameter of wires(P.>05). From these result, it is concluded that diameter of wires is a primary considering factor to reinforce the acrylic resin effectively and, when this requirement is satisfied, increased number of wires or chemical adhesive systems can be expected to produce the additional reinforcing effect.

• Geomechanics and Engineering
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• 제14권4호
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• pp.345-354
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• 2018

Currently, layered geogrid method (LGM) is the commonly practiced technique for reinforcement of slopes. In this paper the geogrid-box method (GBM) is introduced as a new approach for reinforcement of rock-soil slopes. To achieve the objectives of this study, a laboratory setup was designed and the slopes without reinforcements and reinforced with LGM and GBM were tested under the loading of a circular footing. The effect of vertical spacing between geogrid layers and box thickness on normalized bearing capacity and failure mechanism of slopes was investigated. A series of 3D finite element analysis were also performed using ABAQUS software to supplement the results of the model tests. The results indicated that the load-settlement behavior and the ultimate bearing capacity of footing can be significantly improved by the inclusion of reinforcing geogrid in the soil. It was found that for the slopes reinforced with GBM, the displacement contours are widely distributed in the rock-soil mass underneath the footing in greater width and depth than that in the reinforced slope with LGM, which in turn results in higher bearing capacity. It was also established that by reducing the thickness of geogrid-boxes, the distribution and depth of displacement contours increases and a longer failure surface is developed, which suggests the enhanced bearing capacity of the slope. Based on the studied designs, the ultimate bearing capacity of the GBM-reinforced slope was found to be 11.16% higher than that of the slope reinforced with LGM. The results also indicated that, reinforcement of rock-soil slopes using GBM causes an improvement in the ultimate bearing capacity as high as 24.8 times more than that of the unreinforced slope.

• 한국농공학회지
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• 제30권4호
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• pp.94-108
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• 1988

The use of geotextile as reinforcing materials in soil structures has become widespread throughout the world. Geotextile reinforcement has been used in retaining walls, roadbed, embankment stabilization and especially reinforcement of soft foundation, and so on, In the past, however, its design and construction have been performed empirically. In this study, laboratory model tests were carried out in order to investigate the effects of geotextile rein- forcement on vertical and horizontal displacement and other characteristics in soft founda- tions. The experiments were executed in eight treatments ;no geotextile between embank - ment and subsoils, and seven geotextiles with different tensile strength. And such factors as the loading conditions, the tensile strength of geotextiles, the ingredient of geotextiles and the elapsed time were investigate in this study. And the analytical method were executed in order to study the stress and behavior of geotextile - reinforced soil structure by the nonlinear elasto - plastic finite element model. The following conclusions were drawn from this study. 1. Geotextile reinforcement reduced the effects of banking loads on subsoils more effectively with the increase of their tensile strength. 2. As the tensile strength of geotextiles was increase, the rate of the initial vertical disp - lacements of loading plate was reduced inverse proportional to loads, Rowever, the effect of loading was reduced when the loads exceed a certain limits, 3. The effect of reinforcement of nonwoven geotextile was 1.5-4.5 times larger than that of the woven geotextile with equivalent tensile strength. 4. The increased bearing capacity and the reduced settlement are proportioned as the tensile strength of geotextile. 5. The settlement at the long time loading were developed almost all, were completed after 10 days and the additional settlement were not developed since then. 6. The nonlinear elasto - plastic finite element method are accurate to predict the stresses and behayior of geotextile - reinforced soil structures.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 춘계 학술발표회 제20권1호
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• pp.925-928
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• 2008

최근 내진부재 및 기존 구조물의 내진보강요소의 손상제어(Damage tolerance)성능을 충족할 수 있는 변형경화형 시멘트 복합체(Strain-hardening cement composites, SHCC)의 개발 및 활용 연구가 진행 중이며, 하이브리드화에 따른 경제성 및 성능향상 가능성도 보고되고 있다. 그러나 이러한 우수한 성능을 갖는 SHCC 재료가 실구조물의 보수/보강재 및 내진보강부재에 적용되기 위해서는 우수한 인장성능 발현뿐만 아니라, 보강섬유의 단가를 고려한 경제적 효과(Economical efficiency) 및 시공성 (Workability)이 요구된다. 따라서 본 연구에서는 SHCC를 내진부재 및 보강재료로써 적용하기 위한 연구의 일환으로 합성섬유를 하이브리드하여 혼입시 휨 및 인장강도, 변형능력 등 거동특성을 분석함으로써 각 보강섬유의 인장강도 탄성계수 등 기계적 특성과 혼입율에 따른 재료성능과의 상관관계를 비교 분석하여 평가하고자 한다. 또한 물시멘트비를 변수로 하여 시멘트 복합체의 강도특성과 보강섬유의 부착특성 및 균열제어성능을 규명하고자 한다. 이러한 결과를 근거로 향후 SHCC 재료의 실구조물 적용시 요구성능 및 경제성을 고려한 재료배합에 관한 기초자료를 제시하고자 한다.

• 한국보육학회지
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• 제18권1호
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• pp.53-76
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• 2018

본 연구는 보육정책이 가진 아동 발달적 기능에 초점을 두고, 돌봄의 유형이 영아의 발달에 미치는 영향을 살펴보고자 했다. 구체적으로는 돌봄의 유형을 어린이집 돌봄, 가정내 양육으로 구분하고 이를 세분화하여 각 발달영역에 미치는 영향을 비교하고자 하였다. 한국아동패널 1-3차년도 자료를 활용, 발달 영역 별 중다회귀방법으로 분석한 결과는 다음과 같다. 첫째, 어린이집의 이용이 영아의 운동기능 및 언어, 사회성의 모든 발달영역에 미치는 영향이 모두 긍정적으로 작용하는 것으로 나타났다. 둘째, 어린이집 이용 시기에 따라서 각 발달 영역의 수준이 차이를 보였으며, 마지막으로 어린이집 인증여부는 영아의 사회성 발달 측면에서만 그 차이가 나타났다. 종합해 볼 때, 어린이집 이용이 영아의 발달 수준에 긍정적이라고 하더라도 어린이 평가인증 강화와 같은 서비스 질 제고 방안 역시 여전히 필요해 보인다.

• 한국전산구조공학회논문집
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• 제32권6호
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• pp.409-416
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• 2019

본 논문에서는 폭발하중을 받는 철근콘크리트 슬래브의 비선형 해석을 위한 개선된 수치 모델을 제안한다. 제안된 모델은 2축 응력 상태를 반영한 등가 강도에 의해 정의된 응력-변형률 관계를 사용하여 응력 상태를 직접 결정하는 변형률 속도 의존 이등방성 구성 모델을 다룬다. 또한, 균열 발생 후 콘크리트와 철근 사이의 부착 슬립이 점차 확대되어 소성힌지 영역으로 집중된다. 2축 응력 상태에서 콘크리트의 균열 방향은 주응력 방향에 따라 달라지므로 이를 고려한 부착 슬립 모델을 해석에 도입하였다. 해석 모델의 검증을 위해 수치해석과 실험결과의 상관관계 연구(correlation studies)가 수행되었다. 해석결과는 재료모델의 2축 거동과 부착 슬립의 영향을 고려하는 것이 해석결과의 정확성 향상에 중요함을 보여주며 제안된 해석 모델이 철근콘크리트 슬래브 부재의 폭발해석에 효과적으로 사용될 수 있음을 확인하였다.

• KIEAE Journal
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• 제10권5호
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• pp.131-137
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• 2010

The building industry must aim at high-durability and sustainability. A holistic life cycle based approach is recommended to reduce the environmental load. In recent years, technical innovations in the construction industry have advanced to a great extent, and caused the active research and development of high-performance and multifunctional construction materials. Nowadays, various polymer powders have been commercialized to manufacture construction materials in the form of prepackaged-type products, which have rapidly been developed for lack of skilled workmen in construction sites. Recently, terpolymer powders of improved quality have been developed and commercialized as cement modifiers. And, hydrocalumite is a material that can adsorb the chloride ions (Cl-) causing the corrosion of reinforcing bars and liberate the nitrite ions (NO2-) inhibiting the corrosion in reinforced concrete, and can provide a self-corrosion inhibition function to the reinforced concrete. The purpose of this study is to ascertain the self-corrosion inhibition function of polymer-modified mortars using redispersible powders with hydrocalumite. Polymer-modified mortars using VA/E/MMA and VAE redispersible powders are prepared with various calumite contents and polymer-binder ratios, and tested for chloride ion penetration depth, corrosion inhibition. As a result, regardless of the polymer-binder ratio, the replacement of ordinary portland cement with hydrocalumite has a marked effect on the corrosion-inhibiting property of the polymer-modified mortars. Anti-corrosion effect of polymer-modified mortars using VA/E/MMA terpolymer powder with hydrocalumite is higher than that of VAE copolymer powder.