• International Commerce and Information Review
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• v.9 no.1
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• pp.467-491
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• 2007

The Korean Peninsula has the gateway role of Far East Asia in economic aspect, because it is the channel to global world that Korea and Japan should take in the future. Till now, there was no real economic cooperation in service industry for two Koreas. Nevertheless, it is high time that two Koreas have to play a gateway role in order to pave the way to come true their global vision. This paper aims to examine the possibility of economic cooperation between two Koreas in service sector and explore the vision and strategy which are useful for the ways toward peaceful unification on the Korean Peninsula and two Koreas' future survival in the midst of global competition. Economic cooperation in service sector, such as transport, tourism, educational services, etc. between two Koreas means establishing and strengthening the infrastructure of their unification. If there were no cooperation of service sector on the Korean Peninsula, we also could not expect the outcome of economic cooperation and the vision of Korea's unification. To sum up, the strategy recommended for the Korean Peninsula's global vision is that two Koreas should simultaneously open the window of economic cooperation in service sector and link the interface between the Eurasian continent and the Korean Peninsula.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.10 no.4
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• pp.143-147
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• 2011

The system using augmented reality can save the time and cost. It is verified in various fields under the possibility of a technology by solving unrealistic feeling in the virtual space. Therefore, augmented reality has a variety of the potential to be used. Generally, multimodal senses such as visual/auditory/tactile feed back are well known as a method for enhancing the immersion in case of interaction with virtual object. By adapting tangible object we can provide touch sensation to users. a 3D model of the same scale overlays the whole area of the tangible object; thus, the marker area is invisible. This contributes to enhancing immersive and natural images to users. Finally, multimodal feedback also creates better immersion. In this paper, sound feedback is considered. By further improving immersion learning augmented reality for children with the initial step learning content is presented. Augmented reality is in the intermediate stages between future world and real world as well as its adaptability is estimated more than virtual reality.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.3B
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• pp.168-174
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• 2007

All of users who connect to mobile game want to play seamless real-time game without any loads on game servers. However, as for existing methods, it is not available to effectively distribute server loads. Therefore, in this paper, we design and implement an uniform variance-based load balancer for distributing loads of game servers for wireless online games by suitable load balancing methods. With this methods, we can deal with dynamically increasing game servers as the information about load balancing of specific period is applied to the administrator.

• 제어로봇시스템학회:학술대회논문집
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• 1989.10a
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• pp.675-681
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• 1989

As an adaptive control function generator, the CMAC (Cerebellar Model Arithmetic or Articulated Controller) based learning control has drawn a great attention to realize a rather robust real-time manipulator control under the various uncertainties. There remain, however, inherent problems to be solved in the CMAC application to robot motion control or perception of sensory information. To apply the CMAC to the various unmodeled or modeled systems more efficiently, It is necessary to analyze the effects of the CMAC control parameters an the trained net. Although the CMAC control parameters such as size of the quantizing block, learning gain, input offset, and ranges of input variables play a key role in the learning performance and system memory requirement, these have not been fully investigated yet. These parameters should be determined, of course, considering the shape of the desired function to be trained and learning algorithms applied. In this paper, the interrelation of these parameters with learning performance is investigated under the basic learning schemes presented by authors. Since an analytic approach only seems to be very difficult and even impossible for this purpose, various simulations have been performed with prespecified functions and their results were analyzed. A general step following design guide was set up according to the various simulation results.

• BMB Reports
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• v.51 no.10
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• pp.526-531
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• 2018

Protein-Protein Interactions (PPIs) play essential roles in diverse biological processes and their misregulations are associated with a wide range of diseases. Especially, the growing attention to PPIs as a new class of therapeutic target is increasing the need for an efficient method of cell-based PPI analysis. Thus, we newly developed a robust PPI assay (SeePPI) based on the co-translocation of interacting proteins to the discrete subcellular compartment 'processing body' (p-body) inside living cells, enabling a facile analysis of PPI by the enriched fluorescent signal. The feasibility and strength of SeePPI (${\underline{S}}ignal$ ${\underline{e}}nhancement$ ${\underline{e}}xclusively$ on ${\underline{P}}-body$ for ${\underline{P}}rotein-protein$ ${\underline{I}}nteraction$) assay was firmly demonstrated with FKBP12/FRB interaction induced by rapamycin within seconds in real-time analysis of living cells, indicating its recapitulation of physiological PPI dynamics. In addition, we applied p53/MDM2 interaction and its dissociation by Nutlin-3 to SeePPI assay and further confirmed that SeePPI was quantitative and well reflected the endogenous PPI. Our SeePPI assay will provide another useful tool to achieve an efficient analysis of PPIs and their modulators in cells.

• BMB Reports
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• v.45 no.5
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• pp.293-298
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• 2012

The p38 mitogen-activated protein kinase (MAPK) is involved in various processes, including stress responses, development, and differentiation. However, little information on p38 MAPK in insects is available. In this study, a p38 MAPK gene, $Accp38b$, was isolated from $Apis$ $cerana$ $cerana$ and characterized. The quantitative real-time PCR (Q-PCR) analysis revealed that $Accp38b$ was induced by multiple stressors. Notably, the expression of $Accp38b$ was relatively higher in the pupae phase than in other developmental phases. During the pupae phase, Accp38b expression was higher in the thorax than in the head and abdomen and higher in the fat body than in the muscle and midgut. Immunohistochemisty showed significant positive staining of Accp38b in sections from the brain, eyes, fat body, and midgut of $A.$ $cerana$ $cerana$. These results suggest that Accp38b may play a crucial role in stress responses and have multiple aspects function during development.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.835-838
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• 2002

An experiment has been performed using a facility, which simulates the safety depressurization system (SDS) and in-containment refueling water storage tank (IRWST) of APR1400, an advanced PWR being developed in Korea, to investigate the dynamic load resulting from the blowdown of steam from a steam generator through a sparser. The influence of the key parameters, such as air mass, steam pressure, submergence, valve opening time, and pool temperature, on frequency and peak toads was investigated. The blowdown phenomenon was analyzed to find out the real cause of the initiation of bubble oscillation and discrepancy in frequencies between the experiment and calculation by conventional equation for bubble oscillation. The cause of significant damping was discussed and is presumed to be the highly tortuous flow path around bubble. The Rayleigh-Plesset equation, which is modified by introducing method of image, reasonably reproduces the bubble oscillation in a confined tank. Right after the completion of air discharge the steam discharge immediately follows and it condenses abruptly to provide low-pressure pocket. It may contribute to the negative maximum being greater than positive maximum. The subsequently discharging steam does not play as at the driving force anymore.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.65 no.2
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• pp.94-100
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• 2016

A virtual power plant (VPP) technology is a cluster of distributed generation installations. VPP system is that integrates several types of distributed generation sources, so as to give a reliable overall power supply. Virtual power plant systems play a key role in the smart grids concept and the move towards alternative sources of energy. They ensure improved integration of the renewable energy generation into the grids and the electricity market. VPPs not only deal with the supply side, but also help manage demand and ensure reliability of grid functions through demand response (DR) and other load shifting approaches in real time. In this paper, utilizing a variety of distributed generation resources(such as emergency generator, commercial generator, energy storage device), activation scheme of the virtual power plant technology. In addition, through the analysis of the domestic electricity market, it describes a scheme that can be a virtual power plant to participate in electricity market. It attempts to derive the policy support recommendation in order to obtain the basics to the prepared in position of power generation companies for the commercialization of virtual power plant.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3041-3044
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• 2013

Background: The non-steroidal anti-inflammatory drug (NSAID) aspirin (acetylsalicylic acid) is an inhibitor of cyclooxygenase enzymes. Recent studies have shown that aspirin could be used as an anti-tumor drug. Triptolide, the major compound extracted from the Chinese herb Tripteryglum wilfordii Hook.f, has now been shown that it can inhibit tumor growth. The aim of this study was to analyze the anti-tumor efficiency of aspirin and triptolide in cervical cancer cells. Methods: Viability of cervical cancer cell lines was assessed by the MTT method at various concentrations of aspirin and triptolide. Siha and HeLa cell apoptotic analysis was performed by flow cytometry. Real time-PCR and Western Blotting were used to analyze the expression of Bcl-2/Bax, Cyclin D1 and p16. Results: Viability in the combination group was significantly decreased as compared with either drug used alone. Expression change of Bcl-2/Bax, CyclinD1 and p16 appeared to play an important role in the synergistic killing effect on cervical cancer cell apoptosis. Conclusion: Aspirin and triptolide combination treatment may have synergistic anti-tumor effects on cervical cancer cells.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.51 no.2
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• pp.163-169
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• 2018

This study examined the expression of heat shock protein 70 (Hsp70) in red seabream Pagrus major infected by the, acanthocephalan parasites Longicollum pagrosomi. We cloned the full-length Hsp70 cDNA from the liver of the red seabream. The full-length cDNA had a 1,950 bp open reading frame (ORF) that encoded a protein of 650 amino acids. The deduced amino acid sequence of Hsp70 contained all of the conserved Hsp70 family signature sequences and an adenosine triphosphate (ATP)/guanosine triphosphate (GTP) binding motif, including the EEVD (consensus sequence that terminates in Hsp70 family) consensus sequence. The expression of Hsp70 mRNA was upregulated int the fish head-kidney and liver, as determined by quantitative real-time PCR. We quantified the Hsp70 mRNA expression in normal red seabream and fish infected fish by L. pagrosomi. The expression of Hsp70 mRNA was significantly higher in the infected red seabream. These results suggest that Hsp70 play a role of protection against stress and inflammation caused by the parasite and may help maintain homeostasis.