• Title/Summary/Keyword: Radiation resistance

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Proton Irradiation Effects on GaN-based devices

  • Keum, Dongmin;Kim, Hyungtak;Cha, Ho-Young
    • Journal of Semiconductor Engineering
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    • v.2 no.1
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    • pp.119-124
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    • 2021
  • Along with the needs for feasibility in the field of space applications, interests in radiation-hardened electronics is growing rapidly. Gallium nitride (GaN)-based devices have been widely researched so far owing to superb radiation resistance. Among them, research on the most abundant protons in low earth orbit (LEO) is essential. In this paper, proton irradiation effects on parameter changes, degradation mechanism, and correlation with reliability of GaN-based devices are summarized.

Microarray Analysis of Long Non-coding RNA Expression Profile Associated with 5-Fluorouracil-Based Chemoradiation Resistance in Colorectal Cancer Cells

  • Xiong, Wei;Jiang, Yong-Xin;Ai, Yi-Qin;Liu, Shan;Wu, Xing-Rao;Cui, Jian-Guo;Qin, Ji-Yong;Liu, Yan;Xia, Yao-Xiong;Ju, Yun-He;He, Wen-Jie;Wang, Yong;Li, Yun-Fen;Hou, Yu;Wang, Li;Li, Wen-Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3395-3402
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    • 2015
  • Background: Preoperative 5-fluorouracil (5-FU)-based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, CRC cells often develop chemoradiation resistance (CRR). Recent studies have shown that long non-coding RNA (lncRNA) plays critical roles in a myriad of biological processes and human diseases, as well as chemotherapy resistance. Since the roles of lncRNAs in 5-FU-based CRR in human CRC cells remain unknown, they were investigated in this study. Materials and Methods: A 5-FU-based concurrent CRR cell model was established using human CRC cell line HCT116. Microarray expression profiling of lncRNAs and mRNAs was undertaken in parental HCT116 and 5-FU-based CRR cell lines. Results: In total, 2,662 differentially expressed lncRNAs and 2,398 mRNAs were identified in 5-FU-based CRR HCT116 cells when compared with those in parental HCT116. Moreover, 6 lncRNAs and 6 mRNAs found to be differentially expressed were validated by quantitative real time PCR (qRT-PCR). Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for the differentially expressed mRNAs indicated involvement of many, such as Jak-STAT, PI3K-Akt and NF-kappa B signaling pathways. To better understand the molecular basis of 5-FU-based CRR in CRC cells, correlated expression networks were constructed based on 8 intergenic lncRNAs and their nearby coding genes. Conclusions: Changes in lncRNA expression are involved in 5-FU-based CRR in CRC cells. These findings may provide novel insight for the prognosis and prediction of response to therapy in CRC patients.

An Investigation of Self-Radiation Impedance of a Square Piston using an Integral Equation in the Rigid Infinite Baffle (적분식을 이용한 무한배플 사각형 진동체의 자기방사 임피던스 연구)

  • Lee, Jong-Kil;Seo, In-Chang
    • The Journal of the Acoustical Society of Korea
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    • v.14 no.5
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    • pp.58-62
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    • 1995
  • Integral equations of self-radiation impedance of a rectangular piston in a rigid infinite baffle are derived using by polar coordinate. The self-radiation impedance is separated by two parts ; self-radiation resistance and self-radiation reactance. Derived integral equations are simulated by numerical method. Based on the numerical results, self-radiation impedance can be obtained in the low and high frequency ranges without any limited conditions.

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Radiation Effects on the Power MOSFET for Space Applications

  • Lho, Young-Hwan;Kim, Ki-Yup
    • ETRI Journal
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    • v.27 no.4
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    • pp.449-452
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    • 2005
  • The electrical characteristics of solid state devices such as the bipolar junction transistor (BJT), metal-oxide semiconductor field-effect transistor (MOSFET), and other active devices are altered by impinging photon radiation and temperature in the space environment. In this paper, the threshold voltage, the breakdown voltage, and the on-resistance for two kinds of MOSFETs (200 V and 100 V of $V_{DSS}$) are tested for ${\gamma}-irradiation$ and compared with the electrical specifications under the pre- and post-irradiation low dose rates of 4.97 and 9.55 rad/s as well as at a maximum total dose of 30 krad. In our experiment, the ${\gamma}-radiation$ facility using a low dose, available at Korea Atomic Energy Research Institute (KAERI), has been applied on two commercially available International Rectifier (IR) products, IRFP250 and IRF540.

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Ultransonic Effect on the Break-Down Characteristics of Liquid Dielectrics (액체유도체의 절연특성에 미치는 초음파의 영향)

  • Choon Saing Jhoun;Hong Keun Kim;Bong Sik Hong
    • 전기의세계
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    • v.26 no.4
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    • pp.61-67
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    • 1977
  • This paper treats the Ultrasonic effects on the break down characteristics of Liquid Dielectric Material 1) Relative Dielectric constant, Es of Liquid Dielectric Material at a constant temperature decreases in proportion to the irradiated time of Ultrasonic radiation and its intensity, and reaches to a certain saturated value. The saturated value varies with the intensity of Ultrasonic radiation. 2) Power factor of Liquid Dielectric Material at a constant temperature increases in proportion tothe irradiated time of Ultrasonic radiation and its intensity, and reaches to a certain saturated value. The saturated value varies with the intensity of Ultrasonic radiation. 3) Relative resistance of Liquid Dielectric Material at a constant temperature decrease with the irradiated time of Ultrasonic radiation, but the effect of its intensity is very irregular. 4) Break-down strength of Liquid Dielectric Material, at a constant temperature decreases with the irradiated time of Ultrasonic radiation and its intensity, and then reaches to a saturated value.

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Screening of Gamma Radiation-Induced Pathogen Resistance Rice Lines against Xanthomonas oryzae pv. oryzae (방사선을 이용한 벼 흰잎마름병 저항성 돌연변이 벼 계통의 선발)

  • Lim, Chan Ju;Lee, Ha Yeon;Kim, Woong Bom;Ahmad, Raza;Moon, Jae Sun;Kim, Dong Sub;Kwon, Suk-Yoon
    • Journal of Radiation Industry
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    • v.4 no.3
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    • pp.209-213
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    • 2010
  • Bacterial blight is one of the most serious diseases of rice (Oryza sativa L.), and it has been known that Xanthomonas oryzae pv. oryzae (Xoo) causes this disease symptom. To develop resistance rice cultivars against Xoo, 3,000 lines of $M_3$ mutants, which were irradiated with gamma ray, were tested by 'scissor-dip method' primarily, and 191 putative resistant lines were selected. In $M_4$ generation, these lines were screened again with various ways such as measuring of symptom of bacterial blight in leaf, number of tiller, fresh weight, and phenotypic segregation ratio in next generation. Finally, six resistance lines were selected. RT-PCR analysis revealed that these lines displayed high level of R-genes such as Xa21, Pi36, and Pi-ta. These results indicate that mutations by gamma ray cause disruptions of regulatory signal transduction systems of these R-genes. Furthermore, these selected mutants could be useful for the development of rice cultivar resistant to Xoo.

Fabrication and Characterization of C/SiC Composite by Electron Beam Curing (전자선 가교 방법을 이용한 탄소/탄화규소 복합재 제조 및 특성)

  • Shin, Jin-Wook;Jeun, Joon-Pyo;Kang, Phil-Hyun
    • Polymer(Korea)
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    • v.33 no.6
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    • pp.575-580
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    • 2009
  • Carbon fabric-reinforced silicon carbide composites (C/SiC) have attracted a considerable attention for high temperature structural application because of their outstanding oxidation resistance property and thermal shock resistance. In this study, we reported on the preparation of C/SiC composites by the polymer impregnation and pyrolysis (PIP) method. For this, polycarbosilane solution was impregnated into the carbon fabric and then cured by electron beam irradiation under argon atmosphere. Afterwards, the cured composite was pyrolyzed at $1300^{\circ}C$ for 1 h under argon atmosphere to produce the C/SiC composite. The porosity and density of the C/SiC composite were 13.5% and $2.44\;g/cm^3$, respectively, when the impregnation of the carbon fabric with the 30 wt% polycarbosilane solution conducted four times. In addition, in the isothermal experiment at $1500\;^{\circ}C$ in air for 5 h, the 95.9 wt% of the C/SiC composite was remained, indicating that the prepared C/SiC composite has a outstanding oxidation resistance.

A Small Antenna of High Radiation Efficiency Employing a Ground Radiator (그라운드 방사체를 활용한 고효율의 소형 안테나)

  • Choi, Hyeng-Cheul;Lee, Hyung-Jin;Park, Bum-Ki;Jang, Jin-Hyuk;Kim, Hyeong-Dong
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.2
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    • pp.135-143
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    • 2012
  • This paper introduces the method to utilize a terminal ground as a radiator only using reactive components without an antenna structure. Characteristics of the proposed antenna is compared with that of the meander IFA on the same ground plane($40{\times}20mm^2$) for the bluetooth band. From simulation and measurement data, it is found that the proposed antenna using only capacitors provides the highest radiation efficiency. This is because of that the higher inductance reduces radiation resistance of a ground and the capacitor has a lower loss resistance comparing to that of the IFA or the inductor. In spite of the high radiation efficiency, the area ($5{\times}2.5mm^2$) of the proposed antenna is less than half of the area ($12{\times}2.5mm^2$) of the IFA.

Room-temperature tensile strength and thermal shock behavior of spark plasma sintered W-K-TiC alloys

  • Shi, Ke;Huang, Bo;He, Bo;Xiao, Ye;Yang, Xiaoliang;Lian, Youyun;Liu, Xiang;Tang, Jun
    • Nuclear Engineering and Technology
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    • v.51 no.1
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    • pp.190-197
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    • 2019
  • W-K-TiC alloys with different titanium carbide concentrations (0.05, 0.1, 0.25, 0.5, 1, 2) wt.% were fabricated through Mechanical Alloying and Spark Plasma Sintering. The effects of the addition of nano-scaled TiC particles on the relative density, Vickers micro-hardness, microstructure, crystal information, thermal shock resistance, and tensile strength were investigated. It is revealed that the doped TiC nano-particles located at the grain boundaries. The relative density and Vickers micro-hardness of W-K-TiC alloys was enhanced with TiC addition and the highest Vickers micro-hardness is 731.55. As the TiC addition increased from 0.05 to 2 wt%, the room-temperature tensile strength raised from 141 to 353 MPa. The grain size of the W-K-TiC alloys decreased sharply from $2.56{\mu}m$ to 330 nm with the enhanced TiC doping. The resistance to thermal shock damage of W-K-TiC alloys was improved slightly with the increased TiC addition.