• Title/Summary/Keyword: Radiation Dosimetry

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The Low-Radiation Dosimetry Application of "tris" Lyoluminescence using Electron Paramagnetic Resonance at Low Temperature

  • Son, Phil-Kook;Choi, Suk-Won;Kim, Sung-Soo;Gwag, Jin-Seog
    • Journal of Magnetics
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    • v.17 no.3
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    • pp.172-175
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    • 2012
  • We present a method for detecting very weak radiation by analyzing the inner structure of irradiated tris (lyoluminescence) materials using electron paramagnetic resonance (EPR) at low temperature. Organic materials have been looked into for use in emergency dosimetry of inhabitants around radiation accidents. However, this technology has never been applied to imperceptible radiation doses (< 0.5 Gy) because there is no proper method for detecting the change of inner structure of the subject bombed by very weak radiation at room temperature. Our results show that tris materials can be applied as a radiation detectors of very small radiation doses below 0.05 Gray, if EPR is used at low temperature (130 K ${\leq}$ T ${\leq}$ 270 K). The EPR signal intensity from the irradiated-tris sample had barely faded at all after 1 year.

Quality Control of Radiation Dosimetry Service (개인피폭선량 측정기관의 품질관리기준 개발)

  • Lee, Jun-Haeng;Lee, Sang-Bock;Chang, Kun-Jo;Lee, Kwang-Yong;Lee, Hyun-Koo;Kim, Hyeog-Ju;Jin, Gye-Hwan
    • Progress in Medical Physics
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    • v.20 no.4
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    • pp.253-259
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    • 2009
  • We have developed standards based on international criterions for the quality control of dose tested by the measurement institutions of individual exposure doses through improving the reliability of data on the exposure dose of individuals working in radioactive environment and securing the accuracy and reliability of individual dose measurements. Laws related to radiation dose applied to domestic institutions refer to ANSI N13.11.1993, but currently, in U.S. and some other countries the measurement of radiation doses is based on ANSI N13.11.2001 that reduced test categories and tightened the standards. We made efforts to simplify the standards and to reduce the number of dosimeters required in experiment, and avoided preventing or hindering the use of future technologies not approved under the current law such as glass dosimeter and optical stimulation dosimeter. The Quality Management Manual of Radiation Dosimetry Service, Assessment Manual of Radiation Dosimetry Service Accreditation Program, and the Personnel Dosimetry Performance. Criteria for Testing are documents applicable in supervising laboratories.

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A phantom production by using 3-dimentional printer and In-vivo dosimetry for a prostate cancer patient (3D 프린팅 기법을 통한 전립샘암 환자의 내부장기 팬텀 제작 및 생체내선량측정(In-vivo dosimetry)에 대한 고찰)

  • Seo, Jung Nam;Na, Jong Eok;Bae, Sun Myung;Jung, Dong Min;Yoon, In Ha;Bae, Jae Bum;Kwack, Jung Won;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.1
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    • pp.53-60
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    • 2015
  • Purpose : The purpose of this study is to evaluate the usefulness of a 3D printed phantom for in-vivo dosimetry of a prostate cancer patient. Materials and Methods : The phantom is produced to equally describe prostate and rectum based on a 3D volume contour of an actual prostate cancer patient who is treated in Asan Medical Center by using a 3D printer (3D EDISON+, Lokit, Korea). CT(Computed tomography) images of phantom are aquired by computed tomography (Lightspeed CT, GE, USA). By using treatment planning system (Eclipse version 10.0, Varian, USA), treatment planning is established after volume of a prostate cancer patient is compared with volume of the phantom. MOSFET(Metal OXIDE Silicon Field Effect Transistor) is estimated to identify precision and is located in 4 measuring points (bladder, prostate, rectal anterior wall and rectal posterior wall) to analyzed treatment planning and measured value. Results : Prostate volume and rectum volume of prostate cancer patient represent 30.61 cc and 51.19 cc respectively. In case of a phantom, prostate volume and rectum volume represent 31.12 cc and 53.52 cc respectively. A variation of volume between a prostate cancer patient and a phantom is less than 3%. Precision of MOSFET represents less than 3%. It indicates linearity and correlation coefficient indicates from 0.99 ~ 1.00 depending on dose variation. Each accuracy of bladder, prostate, rectal anterior wall and rectal posterior wall represent 1.4%, 2.6%, 3.7% and 1.5% respectively. In- vivo dosimetry represents entirely less than 5% considering precision of MOSFET. Conclusion : By using a 3D printer, possibility of phantom production based on prostate is verified precision within 3%. effectiveness of In-vivo dosimetry is confirmed from a phantom which is produced by a 3D printer. In-vivo dosimetry is evaluated entirely less than 5% considering precision of MOSFET. Therefore, This study is confirmed the usefulness of a 3D printed phantom for in-vivo dosimetry of a prostate cancer patient. It is necessary to additional phantom production by a 3D printer and In-vivo dosimetry for other organs of patient.

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Clinical Implementation of an In vivo Dose Verification System Based on a Transit Dose Calculation Tool for 3D-CRT

  • Jeong, Seonghoon;Yoon, Myonggeun;Chung, Weon Kuu;Chung, Mijoo;Kim, Dong Wook
    • Journal of the Korean Physical Society
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    • v.73 no.10
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    • pp.1571-1576
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    • 2018
  • We developed and evaluated an algorithm to calculate the target radiation dose in cancer patients by measuring the transmitted dose during 3D conformal radiation treatment (3D-CRT) treatment. The patient target doses were calculated from the transit dose, which was measured using a glass dosimeter positioned 150 cm from the source. The accuracy of the transit dose algorithm was evaluated using a solid water phantom for five patient treatment plans. We performed transit dose-based patient dose verification during the actual treatment of 34 patients who underwent 3D-CRT. These included 17 patients with breast cancer, 11 with pelvic cancer, and 6 with other cancers. In the solid water phantom study, the difference between the transit dosimetry algorithm with the treatment planning system (TPS) and the measurement was $-0.10{\pm}1.93%$. In the clinical study, this difference was $0.94{\pm}4.13%$ for the patients with 17 breast cancers, $-0.11{\pm}3.50%$ for the eight with rectal cancer, $0.51{\pm}5.10%$ for the four with bone cancer, and $0.91{\pm}3.69%$ for the other five. These results suggest that transit-dosimetry-based in-room patient dose verification is a useful application for 3D-CRT. We expect that this technique will be widely applicable for patient safety in the treatment room through improvements in the transit dosimetry algorithm for complicated treatment techniques (including intensity modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT).

Energy Response in Chemiluminescence Dosimetry with Sugar and Sorbite

  • Jun, J.S.;Guggenberger, R.;Dalheimer, A.
    • Nuclear Engineering and Technology
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    • v.33 no.6
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    • pp.626-637
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    • 2001
  • A series of study on energy dependence in chemiluminescence dosimetry with sugar and sorbite produced in two different countries was carried out administering a dose of 5 Gy to the samples at six different mean photon energies of 30, 50, 80, 130, 662 and 1250 keV. The results revealed distinct energy dependence of chemiluminescence(CL) output of sugar and sorbite. Although the energy dependence, in general, could be fitted by a polynomial of (os E, with I being radiation energy, up to cubic term, we reached a conclusion that the adoption of a fitting function, $y_{R}$$^{=a}$.(1-e $^{-b.logE}$)$^{c}$ +d, deduced from theoretical energy response curve calculated as the ratio of the mass energy absorption of the samples of interest to the soft tissue is more reasonable and rational. Herecoefficients $y_{R}$ is CL intensity, and a, b, c and d are constants to be determined in the fitting process. Energy dependence of relative sensitivities of one sample to the other, discrepancy in sensitivities of the samples from the two countries, and prominent grain size effect in Sorbitol were also shown.shown.

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Radiation dosimetry of 89Zr labeled antibody estimated using the MIRD method and MCNP code

  • Saeideh Izadi Yazdi ;Mahdi Sadeghi ;Elham Saeedzadeh ;Mostafa Jalilifar
    • Nuclear Engineering and Technology
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    • v.55 no.4
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    • pp.1265-1268
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    • 2023
  • One important issue in using radiopharmaceuticals as therapeutic and imaging agents is predicting different organ absorbed dose following their injection. The present study aims at extrapolating dosimetry estimates to a female phantom from the animal data of 89Zr radionuclide accumulation using the Sparks-Idogan relationship. The absorbed dose of 89Zr radionuclide in different organs of the human body was calculated based on its distribution data in mice using both MIRD method and the MCNP simulation code. In this study, breasts, liver, heart wall, stomach, kidneys, lungs and spleen were considered as source and target organs. The highest and the lowest absorbed doses were respectively delivered to the liver (4.00E-02 and 3.43E-02 mGy/MBq) and the stomach (1.83E-03 and 1.66E-03 mGy/MBq). Moreover, there was a good agreement between the results obtained from both MIRD and MCNP methods. Therefore, according to the dosimetry results, [89Zr] DFO-CR011-PET/CT seems to be a suitable for diagnostic imaging of the breast anomalies for CDX-011 targeting gpNMB in patients with TNBC in the future.

The Performance Test of Teledyne PB-3 Personnel Dosimetry System by Intercomparison Study (국제상호비교검증을 통한 Teledyne PB-3 개인선량계시스템의 성능시험)

  • Lee, Sang-Yoon;Lee, Hyung-Sub;Kim, Jung-Lyul;Yoon, Suk-Chul
    • Journal of Radiation Protection and Research
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    • v.19 no.2
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    • pp.133-145
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    • 1994
  • Recently, the Ministry of Science and Technology issued a Ministerial Ordinance (No 1992-15) about the technical criteria on personnel radiation dosimetry. In today's climate, it is important to demonstrate and document that the processor's systems and services to others meet national standards of quality. The purpose of this study is to verify the performance of the Teledyne PB-3 personnel dosimetry system that is generally used in Korea Atomic Energy Research Institute(KAERI) by intercomparison with Oak Ridge National Laboratory. The KAERI has been participated in this personnel dosimetry intercomparison study(PDIS) program since 1991 and it could be possible to test and calibrate personnel monitoring system. This report presents a summary and analysis of by about 50 dose equivalent measurements reported for PDIS-16 through 18 (1991 -1993) with emphasis on neutron dose equivalent sensitivity, accuracy and precision. Relationships of the PDIS results to occupational neutron monitoring and methods to improve personnel dosimetry performance are also discussed.

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In Vivo Dosimetry with MOSFET Detector during Radiotherapy (방사선 치료 중 MOSFET 검출기를 이용한 체표면 선량측정법)

  • Kim Won-Taek;Ki Yong-Gan;Kwon Soo-Il;Lim Sang-Wook;Huh Hyun-Do;Lee Suk;Kwon Byung-Hyun;Kim Dong-Won;Cho Sam-Ju
    • Progress in Medical Physics
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    • v.17 no.1
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    • pp.17-23
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    • 2006
  • In Vivo dosimetry is a method to evaluate the radiotherapy; it is used to find the dosimetric and mechanical errors of radiotherapy unit. In this study, on-line In Vivo dosimetry was enabled by measuring the skin dose with MOSFET detectors attached to patient's skin during treatment. MOSFET dosimeters were found to be reproducible and independent on beam directions. MOSFET detectors were positioned on patient's skin underneath of the dose build-up material which was used to minimize dosimetric error. Delivered dose calculated by the plan verification function embedded in the radiotherapy treatment planning system (RTPs), was compared with measured data point by point. The dependency of MOSFET detector used in this study for energy and dose rate agrees with the specification provided by manufacturer within 2% error. Comparing the measured and the calculated point doses of each patient, discrepancy was within 5%. It was enabled to verify the IMRT by using MOSFET detector. However, skin dosimetry using conventional ion chamber and diode detector is limited to the simple radiotherapy.

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LiF TLD in TLD Holder for In Vivo Dosimetry (생체 내 선량측정을 위한, TLD홀더에 넣은 LiF TLD)

  • Kim Sookil;Loh John J.K.;Min Byungnim
    • Radiation Oncology Journal
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    • v.19 no.3
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    • pp.293-299
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    • 2001
  • Prupose : LiF TLD has a problem to be used in vivo dosimetry because of the toxic property of LiF. The aim of this study is to develop new dosimeter with LiF TLD to be used in vivo dosimetry. Materials and methods : We designed and manufactured the teflon box(here after TLD holder) to put TLD in. The external size of TLD holder is $4\times4\times1\;mm^3$ To estimate the effect of TLD holder on TLD response for radiation, the linearity of TLD response to nominal dose were measured for TLD in TLD holder. Measurement were peformed in the 10 MV x-ray beam with LiF TLD using a solid water phantom at SSD of 100 cm. Percent Depth Dose (PDD) and Tissue-Maximum Ratio (TMR) with varying phantom thickness on TLD were measured to find the effect of TLD holder on the dose coefficient used for dose calculation in radiation therapy. Results : The linearity of response of TLD in TLD holder to the nominal dose was improved than TLD only used as dosimeter And in various measurement conditions, it makes a marginnal difference between TLD in TLD holder and TLD only in their responses. Conclusion : It was proven that the TLD in TLD holder as a new dosimetry could be used in vivo dosimetry.

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