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The Severity and Variables Influencing Depression in Cancer Patients with Pain (통증이 있는 암환자의 우울 정도 및 우울에 영향을 미치는 요인)

  • Kim, Hyun-Sook;Yun, Young-Ho;Lee, So-Woo;Heo, Dae-Seog;Son, Haeng-Mi;Huh, Bong-Yul
    • Journal of Hospice and Palliative Care
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    • v.2 no.2
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    • pp.125-137
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    • 1999
  • Purpose : Surveying the rates, severity, and variables influencing depression and their correlation between pain and depression in Korean cancer patients, we attempted to provide a basic database for the effective depression management program. Methods : The results of survey were colleted from 10 patients who were hospitalized at Seoul National University Hospital for cancer treatment from February to June of 1999. Factors of depression and the level of pain were examined by self-reported survey employing Korean version of Beck Depression Inventory(BDI) and an abridged version of Brief pain Inventory respectively. The purpose of this study and guidelines for the questionnaires were clearly explained to participating patients by Resgitered Nurses before answering the survey. Demographic and clinical characteristics of patients were compiled by reviewing their medical records in corporation with a family physician. The difference in the level of depression among patient groups was analyzed with the t-test and ANOVA, and the correlation between variables with Pearson correlation coefficient. Results : 1) 142 subjects comprised 79 male and 63 female, and their mean age was 51.86. 2) The mean scores of the worst pain for last 24-hours was 6.08(SD 2.23), the average pain for last 24-hours 4.44(SD 1.85), and the mean scores of pain at the time of survey 3.48(SD 2.25), while the mean scores of the least pain for last 24-hours 2.25(SD 1.83). 3) The mean BDI scores were 23.73(SD 0.99), and 55.6% of patients were evaluated to be in depression(cutting point 21). Scores of depression for cancer patients were higher than normal population. 4) The correlation between worst pain for last 24-hours and depression(r=0.252, P=0.002), average pain for last 24-hours and depression(r=0.225, P=0.007), present pain and depression(r=0.291, P=0.000) were significant. 5) Significant differences were found among groups of cancer patients with pain with respect to gender(t=3.59, p=0.000), level of education(F=4.063, P=0.009), ECOG(F=3.352, P=0.021). There was significant positive correlation between depression and pain(r=0.171, P=0.042). Conclusions : More than 50% of cancer patients with pain are suffering from depression. We have shown that the variables like the degree of pain, gender, level of education, ECOG, and age are significantly related to the depression in cancer patients. The findings of this study may be used for assessing high-risk patients in need of intervention and for planning effective therapeutic strategies for them after the routine assessment. Further study is necessary to investigate the cultural differences and the variables influencing on depression in Korean cancer patients.

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Expression of Rice Chitinase Gene in Genetically Engineered Tomato Confers Enhanced Resistance to Fusarium Wilt and Early Blight

  • Jabeen, Nyla;Chaudhary, Zubeda;Gulfraz, Muhammad;Rashid, Hamid;Mirza, Bushra
    • The Plant Pathology Journal
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    • v.31 no.3
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    • pp.252-258
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    • 2015
  • This is the first study reporting the evaluation of transgenic lines of tomato harboring rice chitinase (RCG3) gene for resistance to two important fungal pathogens Fusarium oxysporum f. sp. lycopersici (Fol) causing fusarium wilt and Alternaria solani causing early blight (EB). In this study, three transgenic lines TL1, TL2 and TL3 of tomato Solanum lycopersicum Mill. cv. Riogrande genetically engineered with rice chitinase (RCG 3) gene and their R1 progeny was tested for resistance to Fol by root dip method and A. solani by detached leaf assay. All the R0 transgenic lines were highly resistant to these fungal pathogens compared to nontransgenic control plants. The pattern of segregation of three independent transformant for Fol and A. solani was also studied. Mendelian segregation was observed in transgenic lines 2 and 3 while it was not observed in transgenic line 1. It was concluded that introduction of chitinase gene in susceptible cultivar of tomato not only enhanced the resistance but was stably inherited in transgenic lines 2 and 3.

Effect of Academic Engagement and Academic Self-efficacy on Problem Solving Ability of Nursing students (간호대학생의 학습열의, 학업적 자기효능감이 문제해결능력에 미치는 영향)

  • Eun Kyung, Byun;Hyo Jin Park
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.4
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    • pp.245-252
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    • 2023
  • The purpose of this study was to investigate the effect of academic engagement, academic self-efficacy of problem solving ability in nursing students. Data were collected from 219 nursing students in B city and analyzed by descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and multiple regression using SPSS/WIN 22.0. The degree of problem solving ability in nursing students was 4.00±0.51. There were significant differences in problem solving ability with major satisfaction(F=9.476, p<.001), class satisfaction (F=3.079, p<.001). There was positive correlation between problem solving ability and academic engagement (r=.560, p<.001), academic self-efficacy(r=.634, p<.001). There was positive correlation between academic engagement and academic self-efficacy(r=.769, p<.001). The factors affecting problem solving ability of the study subjects were academic engagement(β=.177, p=.031), academic self-efficacy(β=.498, p<.001), with an explanatory power of 41.0%. Therefore to increase aacademic engagement and academic self-efficacy of nursing students, it is necessary to develop the program for improving the problem solving ability of nursing students.

Convergence Effects of Nurse's Perception of Patient Safety Culture and Safety Control on Safety Performance in General Hospital (종합병원 간호사의 환자안전문화 인식과 안전통제감이 안전이행에 미치는 융복합적 영향)

  • Kim, Yoon-Lee;Lee, Myung-In;Chin, Eun-Young
    • Journal of Digital Convergence
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    • v.14 no.7
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    • pp.201-211
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    • 2016
  • This descriptive study was aimed to identify factors which influence safety performance through evaluation of nurse's perception of patient safety culture and safety control in general hospital. Self-administered web surveys were conducted by 342 nurses who employed in general hospital from May 09 to May 13, 2014. Data were analyzed using the SPSS/WIN 21.0 statistical program. The results of analysis revealed that the score of safety culture perception was 3.34, safety control was 3.50, safety performance was 3.53 and all scores were higher level than usual. There were significant positive correlation between safety performance and perception of patient safety culture, safety control (r=.463~.645, p<.001). The positively influencing factors of safety performance are marital status, frequency of accident reports, general perception of patient safety and safety control. Explanation ratio of the variables for the safety performance was 52.0% in this study(F=4.252, p=.004). This study findings suggest that it would be useful as a preliminary report of nurse's intervention strategy through confirmation of the nurse's positive effect to improve safety performance in general hospital.

Effects of anxiety, depression, social support, and physical health status on the health-related quality of life of pregnant women in post-pandemic Korea: a cross-sectional study

  • Hyun Kyoung Kim;Geum Hee Jeong;Hye Young Min
    • Women's Health Nursing
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    • v.29 no.3
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    • pp.243-252
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    • 2023
  • Purpose: This study aimed to examine the effects of anxiety, depression, social support, and physical health status on the health-related quality of life of Korean pregnant women using Spilker's quality of life model. Methods: This was a cross-sectional study with a correlational design. The participants included 166 pregnant women who were recruited via convenience sampling at two healthcare centers in South Korea. Questionnaires were collected from April 22 to May 29, 2023, in two cities in South Korea. The EuroQol-5D-3L, General Anxiety Disorder-7, Patient Health Questionnaire-2, Perceived Social Support through Others Scale-8, and EuroQol visual analog scale were used to assess the study variables. The t-test, Pearson correlation coefficients, and multiple regression tests were conducted using IBM SPSS ver. 26.0. Results: Statistically significant correlations were identified between the health-related quality of life of pregnant women and anxiety (r=.29, p<.001), depression (r=.31, p<.001), social support (r=-.34, p<.001), and physical health status (r=-.44, p<. 001). Physical health status (β=-.31, p<.001) and social support (β=-.21, p=.003) had the greatest effect on health-related quality of life (F=15.50, p<.001), with an explanatory power of 26.0%. Conclusion: The health-related quality of life of pregnant women was affected by social support and physical health status. This study demonstrated that physical health and social support promotion can improve the health-related quality of life of pregnant women. Healthcare providers should consider integrating physical health into social support interventions for pregnant women in the post-pandemic era.

Influencing Factors of Nursing Performance for Life Care of Delirium Patients among Nursing Students (섬망환자의 라이프케어를 위한 간호학생의 섬망간호 수행 영향요인)

  • Oh, Hyo-Sook;Chang, Mi-Young
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.4
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    • pp.401-410
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    • 2019
  • This study was conducted to identify factors affecting nursing performance of delirium among nursing students. A total of 252 fourth year students were recruited from nursing department in Gwangju. Structured questionnaire was self-administrated from April to September, 2017. The used statistical analysis were t-test, ANOVA, Pearson's coefficient and multiple regression analysis. Knowledge of delirium 29.0±7.24, self-confidence in the care for delirium 71.65±28.55 and nursing performance level for patients with delirium was 41.16±8.97. Nursing performance of delirium had significant positive correlations with delirium knowledge, self-confidence of delirium care. In multiple regression analysis, nursing experience for delirium patients, self-confidence of delirium care, practice experience in intensive care unit, use of nursing diagnosis related to delirium, and satisfaction of clinical practice were significant factors of nursing performance of delirium explaining 29.8% of the variables. In conclusion, to enhance nursing performance of delirium, it is necessary to develop educational program for increasing nursing experience for delirium patients during clinical practice and self-confidence of delirium care.

Development and Characterization of Tissue Equivalent Proportional Counter for Radiation Monitoring in International Space Station

  • Nam, Uk-Won;Lim, Chang Hwy;Lee, Jae Jin;Pyo, Jeonghyun;Moon, Bong-Kon;Lee, Dae-Hee;Park, Youngsik;Kim, Hyun Ok;Moon, Myungkook;Kim, Sunghwan
    • Journal of Astronomy and Space Sciences
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    • v.30 no.2
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    • pp.107-112
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    • 2013
  • Tissue equivalent proportional counter (TEPC) can measure the Linear Energy Transfer (LET) spectrum and calculate the equivalent dose for the complicated radiation field in space. In this paper, we developed and characterized a TEPC for radiation monitoring in International Space Station (ISS). The prototype TEPC which can simulate a 2 ${\mu}m$ of the site diameter for micro-dosimetry has been tested with a standard alpha source ($^{241}Am$, 5.5 MeV). Also, the calibration of the TEPC was performed by the $^{252}Cf$ neutron standard source in Korea Research Institute of Standards and Science (KRISS). The determined calibration factor was $k_f=3.59{\times}10^{-7}$ mSv/R.

Oxidative Stress in the Heart of Rats Infected with Trypanosoma evansi

  • Baldissera, Matheus D.;Souza, Carine de F.;Bertoncheli, Claudia M.;da Silveira, Karine L.;Grando, Thirssa H.;Porto, Bianca C.Z.;Leal, Daniela B.R.;Da Silva, Aleksandro S.;Mendes, Ricardo E.;Stefani, Lenita M.;Monteiro, Silvia G.
    • Parasites, Hosts and Diseases
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    • v.54 no.3
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    • pp.247-252
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    • 2016
  • This study was conducted to investigate the occurrence of oxidative stress in the heart tissue of rats infected with Trypanosoma evansi. Rats were divided into 2 groups (A and B) with 12 animals each, and further subdivided into 4 subgroups (A1 and A2, 6 animals/each; and B1 and B2, 6 animals/each). Animals in the groups B1 and B2 were subcutaneously inoculated with T. evansi. Thiobarbituric acid reactive substances (TBARS), superoxide dismutase activity (SOD), glutathione S-transferase activity (GST), reduced glutathione activity (GSH), and non-protein thiols (NPSH) in the heart tissue were evaluated. At day 5 and 15 post-infection (PI), an increase in the TBARS levels and a decrease in the SOD activity (P<0.05) were observed. GSH and GST activities were decreased in infected animals at day 15 PI (P<0.05). Considering the proper functioning of the heart, it is possible that the changes in the activity of these enzymes involved in the oxidative stress may be related, at least in part, in the pathophysiology of rats infected with T. evansi.

Reproductive Biology of Common Octopus, Octopus vulgaris in the South Sea of Korea (한국 남해안에 분포하는 참문어(Octopus vulgaris)의 생식생물학적 연구)

  • Kim, Yeong-Hye;Kang, Hyun-Jung;Lee, Eun-Hui;Lee, Dong-Woo;Chang, Dae-Soo;Gwak, Woo-Seok
    • The Korean Journal of Malacology
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    • v.24 no.3
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    • pp.161-166
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    • 2008
  • Samples were collected monthly from coastal water around Tongyeong and Sacheon in Gyeongsangnam-do, Korea, using traps. A total of 748 Octopus vulgaris were sampled from February 2007 to January 2008. Monthly changes of maturity stages and sex ratio of the common octopus were observed. Mean biomass (total wet weight) of the female specimens ranged from 129.8 to 3,381.4 g and that of the male specimens ranged from 128.6 and 2,378.4 g. The spawning periods were May to June and September. The fecundity ranged from 5,715 eggs at 252.0 g to 240,990 eggs at 3,381.4 g of total wet weight. The relationship between total wet weight (TW) and fecundity (F) was F = 26.539 $TW^{1.1548}$ ($r^2=0.8199$) and fecundity increased with total wet weight. Sex ratio was not significantly different from the 1:1 (p > 0.05).

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Factors Influencing Perception of Good Death among the Community-dwelling Elderly (재가노인의 좋은 죽음에 대한 인지도와 가족지지의 영향)

  • Kim, Chun-Gill
    • Journal of Hospice and Palliative Care
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    • v.17 no.3
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    • pp.151-160
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    • 2014
  • Purpose: This study was conducted to investigate perception of good death among the community-dwelling elderly and identify factors related to the perception. Methods: A questionnaire survey was carried out using a convenient sampling method (N=317). Data were analyzed by applying descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient, and stepwise multiple regression. Results: Participants scored an average of 3.35 on a 4-point scale for the perception level of good death. They scored higher on the factor of personal control that other factors affecting the perception. Good death was positively correlated with family support (r=0.252). Family support (${\beta}$=0.287) and gender (${\beta}$=0.197) significantly influenced the elderly's perception of good death. These variables accounted for 10.2% of the total variance. Conclusion: The results show that family support is an important factor for the perception of good death among the elderly. Therefore, family support should be carefully considered to ensure good death for more senior citizens. Our findings can be utilized to support programs such as death education for the elderly.