• Journal of Life Science
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• v.12 no.3
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• pp.325-331
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• 2002

There is growing interest ill understanding the role and mechanisms of flavonoid as antioxidant on LDL. The antioxidative activity of flavonoid typically present in Oenothers odorate Jacquin was investigated in vitro using a human LDL oxidation assay. In present work, LDL was incubated with increasing concentrations of extracts of extracts of Oenothers odorate Jacquin and LDL oxidation was started by adding CuSO$_4$to the media. Substances in leaves extracts of Oenothers odorate Jacquin are capable of inhibiting the initiation and the propagation of LDL oxidation. They inhibit LDL oxidation, monitored by thiobarbituric acid-reactive substances(TBARS), as well as modification as shown through direct measurement of electrophoretic mobility, diene conjugates. Inhibition is a dose dependent effect that becomes already apparent at concentration of extracts as low as 40$\mu\textrm{g}$/mL. Inhibition is almost complete at 80$\mu\textrm{g}$/mL. Extracts of Oenothers odorate Jacquin were more potent antioxidative activity than either ascorbic acid and dl-a -tocopherol.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2012.05a
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• pp.278-281
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• 2012

Numerical studies were performed to investigate the three-dimensional front structure and dynamics features of detonation wave propagating in a circular tube such as Pulse Detonation Engine (PDE). By carrying out a series of parametric study using one step irreversible Arrhenius kinetics model, mechanisms of the three-dimensional front structure were investigated for two-, three-, four and six-cell mode detonations. A comparison with two-dimensional results, the effects of slapping transverse waves in radial direction were confirmed. In the all muti-cell modes, the detonation front structures and smoked-records on the wall are formed by the propagation of transverse waves along the wall in clockwise and counter-clockwise while the slapping move in radial direction. And the strength of reflected waves on the curved wall is changed by the multi-dimensional confinement effect.

• Geomechanics and Engineering
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• v.19 no.1
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• pp.49-60
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• 2019

Crack instability propagation during coal and rock mass failure is the main reason for electromagnetic radiation (EMR) generation. However, original cracks on coal and rock mass are hard to study, making it complex to reveal EMR laws and mechanisms. In this paper, we prefabricated cracks of different inclinations in coal and rock samples as the analogues of the native cracks, carried out uniaxial compression experiments using these coal and rock samples, explored, the effects of the prefabricated cracks on EMR laws, and verified these laws by measuring the surface potential signals. The results show that prefabricated cracks are the main factor leading to the failure of coal and rock samples. When the inclination between the prefabricated crack and axial stress is smaller, the wing cracks occur first from the two tips of the prefabricated crack and expand to shear cracks or coplanar secondary cracks whose advance directions are coplanar or nearly coplanar with the prefabricated crack's direction. The sample failure is mainly due to the composited tensile and shear destructions of the wing cracks. When the inclination becomes bigger, the wing cracks appear at the early stage, extend to the direction of the maximum principal stress, and eventually run through both ends of the sample, resulting in the sample's tensile failure. The effect of prefabricated cracks of different inclinations on electromagnetic (EM) signals is different. For samples with prefabricated cracks of smaller inclination, EMR is mainly generated due to the variable motion of free charges generated due to crushing, friction, and slippage between the crack walls. For samples with larger inclination, EMR is generated due to friction and slippage in between the crack walls as well as the charge separation caused by tensile extension at the cracks' tips before sample failure. These conclusions are further verified by the surface potential distribution during the loading process.

• Geomechanics and Engineering
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• v.17 no.1
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• pp.47-56
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• 2019

Crossing (X-type) flaws are commonly encountered in rock mass. However, the crack coalescence and failure mechanisms of rock mass with X-type flaws remain unclear. In this study, we investigate the compressive failure process of rock-like specimens containing two X-type flaws aligned in the loading direction. For comparison purposes, compressive failure behavior of specimens containing two aligned single flaws is also studied. By examining the crack coalescence behavior, two characteristics for the aligned X-type flaws under uniaxial compression are revealed. The flaws tend to coalesce by cracks emanating from flaw tips along a potential path that is parallel to the maximum compressive stress direction. The flaws are more likely to coalesce along the coalescence path linked by flaw tips with greater maximum circumferential stress if there are several potential coalescence paths almost parallel to the maximum compressive stress direction. In addition, we find that some of the specimens containing two aligned X-type flaws exhibit higher strengths than that of the specimens containing two single parallel flaws. The two underlying reasons that may influence the strengths of specimens containing two aligned X-type flaws are the values of flaw tips maximum circumferential stresses and maximum shear stresses, as well as the shear crack propagation tendencies of some secondary flaws. The research reported here provides increased understanding of the fundamental nature of rock/rock-like material failure in uniaxial compression.

• Nuclear Engineering and Technology
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• v.53 no.6
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• pp.1821-1833
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• 2021

The gas-liquid counter-current flow limitation (CCFL) is closely related to efficient and safety operation of many equipment in industrial cycle. Air-water countercurrent flow experiments were performed in a tube with diameter of 25 mm to understand the triggering mechanism of CCFL. A parallel electrode probe was utilized to measure film thickness whereby the time domain and frequency domain characteristics of liquid film was obtained. The amplitude of the interface wave is small at low liquid flow rate while it becomes large at high liquid flow rate after being disturbed by the airflow. The spectral characteristic curve shows a peak-shaped distribution. The crest exists between 0 and 10 Hz and the amplitude decreases with the frequency increase. The analysis of visual observation and characteristic of film thickness indicate that two flooding mechanisms were identified at low and high liquid flow rate, respectively. At low liquid flow rate, the interfacial waves upward propagation is responsible for the formation of CCFL onset. While flooding at high liquid flow rate takes place as a direct consequence of the liquid bridging in tube due to the turbulent flow pattern. Moreover, it is believed that there is a transition region between the low and high liquid flow rate.

• Earthquakes and Structures
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• v.20 no.1
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• pp.71-86
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• 2021

This paper focuses on the development and assessment of the expected damage for the rocking response of rigid anchored blocks, with irregular geometry and non-uniform mass distribution, considering the site conditions and the seismicity of Mexico City. The non-linear behavior of the restrainers is incorporated to evaluate the pure tension and tension-shear failure mechanisms. A probabilistic framework is performed covering a wide range of block sizes, slenderness ratios and eccentricities using physics-based ground motion simulation. In order to incorporate the uncertainties related to the propagation of far-field earthquakes with a significant contribution to the seismic hazard at study sites, it was simulated a set of scenarios using a stochastic summation methods of small-earthquakes records, considered as Empirical Green's Function (EGFs). As Engineering Demand Parameter (EDP), the absolute value of the maximum block rotation normalized by the body slenderness, as a function of the peak ground acceleration (PGA) is adopted. The results show that anchorages are more efficient for blocks with slenderness ratio between two and three, while slenderness above four provide a better stability when they are not restrained. Besides, there is a range of peak intensities where anchored blocks located in soft soils are less vulnerable with respect to those located in firm soils. The procedure used in here allows to take decisions about risk, reliability and resilience assessment of different types of contents, and it is easily adaptable to other seismic environments.

• Geomechanics and Engineering
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• v.29 no.2
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• pp.99-111
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• 2022

Instability of bolted rock mass has been a major hazard in the underground coal mining industry for decades. Developing effective support guidelines requires understanding of complex bolted rock mass failure mechanisms. In this study, the dynamic failure behavior, mechanical behavior, and energy evolution of a laboratory-scale bolted specimens is studied by conducting laboratory static-dynamic coupled loading tests. The results showed that: (1) Under static-dynamic coupled loading, the stress-strain curve of the bolted rock mass has a significant impact velocity (strain rate) correlation, and the stress-strain curve shows rebound characteristics after the peak; (2) There is a critical strain rate in a rock mass under static-dynamic coupled loading, and it decreases exponentially with increasing pre-static load level. Bolting can significantly improve the critical strain rate of a rock mass; (3) Compared with a no-bolt rock mass, the dissipation energy ratio of the bolted rock mass decreases exponentially with increasing pre-static load level, the ultimate dynamic impact energy and dissipation energy of the bolted rock mass increase significantly, and the increasing index of the ratio of dissipation energy increases linearly with the pre-static load; (4) Based on laboratory testing and on-site microseismic and stress monitoring, a design method is proposed for a roadway bolt support against dynamic load disturbance, which provides guidance for the design of deep underground roadway anchorage supports. The research results provide new ideas for explaining the failure behavior of anchorage supports and adopting reasonable design and construction practices.

• Korean Chemical Engineering Research
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• v.61 no.1
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• pp.155-161
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• 2023

Ion concentration polarization (ICP) is one of the essential important mechanisms for biomolecule preconcentration devices as well as a fundamental transport phenomenon found in electrodialysis, electrochemical cell, etc. The ICP triggered by externally applied voltage enables the biomolecular analyte to be preconcentrated at an arbitrary position by a locally amplified electric field inside the microchannel. Conventional preconcentration methodologies using the ICP have two limitations: uncertain equilibrium position and hydrodynamic instability of preconcentration plug. In this work, a new preconcentration method in the dead-end microchannel around cation exchange membrane was numerically studied to resolve the limitations. As a result, the numerical model showed that the analyte was concentrated at a shock front developed in a geometrically confined dead-end channel. Furthermore, the electrokinetic behaviors for preconcentration dynamics were analyzed by changing microchannel's applied voltage and volumetric charge concentration of microchannel as key parameters to describe the dynamics. This work would provide an effective means for a point-of-care platform that requires ultra-fast preconcentration method.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.3B
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• pp.213-219
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• 2009

In densely urban areas, features such as the sewer system, buildings and river banks have an effect on flow dynamics and flood propagation, and will therefore be accounted for in the model set-up. While two-dimensional (2D) flood models of urban areas are at the forefront of current research into flood inundation mechanisms, they are however constrained by inadequate parameters of topography, and insufficient and inaccurate data. In this study, an urban flood model (overland flow, 2D urban flood flow and sewer flow) was combined and applied at Samcheok city which was damaged by inundation in 2002, in order to simulate inundation depth. The influence of buildings and pumping capacity was also analyzed to estimate the inundated depth in the study area. As a result, it was found that urban inundated depth are affected by pumping capacity directly and it increased about 20-30 cm on most of the modeled area with a building share rate of 0.2-0.6 per unit grid.

• Asian Journal for Public Opinion Research
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• v.12 no.1
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• pp.53-74
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• 2024

The proliferation of health misinformation gained momentum amidst the outbreak of the novel coronavirus disease 2019 (COVID-19). People stuck in their homes, without work pressure, regardless of health concerns towards personal, family, or peer groups, consistently demanded information. People became engaged with misinformation while attempting to find health information content. This study used the content analysis method and analyzed 1,154 misinformation stories from four prominent signatories of the International Fact-Checking Network during the pandemic. The study finds the five main categories of misinformation related to the COVID-19 pandemic. These are 1) the severity of the virus, 2) cure, prevention, and treatment, 3) myths and rumors about vaccines, 4) health authorities' guidelines, and 5) personal and social impacts. Various sub-categories supported the content characteristics of these categories. The study also analyzed the emotional valence of health misinformation. It was found that misinformation containing negative sentiments got higher engagement during the pandemic. Positive and neutral sentiment misinformation has less reach. Surprise, fear, and anger/aggressive emotions highly affected people during the pandemic; in general, people and social media users warning people to safeguard themselves from COVID-19 and creating a confusing state were found as the primary motivation behind the propagation of misinformation. The present study offers valuable perspectives on the mechanisms underlying the spread of health-related misinformation amidst the COVID-19 outbreak. It highlights the significance of discerning the accuracy of information and the feelings it conveys in minimizing the adverse effects on the well-being of public health.