• 대한약침학회지
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• 제13권2호
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• pp.101-110
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• 2010

Objectives : This experimental study was performed to investigate the effect of Fel Ursi & Bovis Calculus pharmacopuncture solution(FUBCPS) manufactured by using alcohol/water extraction method for identify ing the use of it as eyedrops. Methods: FUBCPS was manufactured by using alcohol/water extraction method. Measure the size of inhibition zone and MIC(Minimum Inhibition Concentration) after administering FUBCPS on bacterial species. Staphylococcus aureus. Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum and Candida albicans, which cause keratitis. Administering cravit(Levonoxacin medicine) on bacterial species also performed to compare the anti-bacterial potency of this material, measured by using the size of inhibition zone Results : After administering FUBCPS on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans). there was no response to MIC and there was no anti -bacterial potency also. Conclusions : This study suggests that FUBCPS dose not have anti-bacterial effects on bacterial species which cause Keratitis. These study result recommends that we need to research more on herbal medicines of eye drop which have anti-bacterial effects on keratitis

• 한국생활과학회지
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• 제16권5호
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• pp.1007-1019
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• 2007

The purpose of this study is to investigate the effect of achromatic shirt and chromatic tie combination on image of menswear. This experiment was designed by shirt color(N9, N7, N4, N2), tie color(red, orange, yellow, green, blue, purple), tie tone(vivid, light, dull, dark), and perceiver gender(a male, a female). The experimental materials developed for this study were a set of stimulus and response scales. The stimuli were 96 upper body photographs and 26 7-point bi-polar adjectives were used to evaluate the image. The subjects of this research were 480 male and 480 female college students. The data was analyzed by using SPSS program. Analysis methods were four-way ANOVA. The items of the adjectives were classified into 4 image factor: potency, activity, attractiveness, and visibility. Shirt color, tie color, tie tone influenced on the 4 image dimension greatly by interaction as well as independently. Dull or dark tone tie had an effect on the formation of potency image. And white color shirt, vivid or light tone tie had an effect on the formation of activity image. White or black shirt had a positive effect on attractiveness, and black shirt or vivid tone tie was effective for visible image.

• KSBB Journal
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• 제26권2호
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• pp.157-164
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• 2011

Five assays for anti-HBs were compared to improve potency test of Human lgG preparations. The three commercial EIA kits were optimized including dose response curve ranges and compared by conducting a co-laboratory study. After selecting the most reproducible EIA kit, methods comparison was performed with 22 samples in 5 different days. As a result, EIA (7.7 ${\pm}$ 5.3%) and MEIA (AxSYM: 3.7 ${\pm}$ 1.9%, IMx: 1.6 ${\pm}$ 0.8%) showed precision and accuracy (100.1 ${\pm}$ 12.6%). Therefore, the validated EIA assay was established and it is believed to be comparable to current MEIA.

• 한국의류학회지
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• 제29권2호
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• pp.318-327
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• 2005

The purpose of this study was to analyze the image perception of modern fashion according to erotic expressions ans erotic levels. The research methods werea quasi-experimental research. The experimental materials developed for the study were a set of stimuli and a responsse scale. The stimuli was consisted of 15 photographs according to erotic expressions and erotic levels. The reponse scale consisted of semantic differential scales. The subjects consisted of 254 male and 260 female undergraduate students of Chungnam National University by a convenient sampling method. The data were analyzed by factor analysis, ANOVA, Duncan's multiple range test and t-test. Result were as follows ; 1) The fashion image of erotic experessions and levels, were categorized into 3 images factors : sexy-potency, modesty, attractiveness. 2) The erotic expressions significantly affected on three image factors 3) The erotic levels showed significant differences in three image dimensions and stronger erotic levels pressented more sexy-potency, less models and attractive images. 4) The erotic expressions showed interaction effects with the erotic levels in three image dimensions. 5) Subject's gender had a significant difference on fashion image perception : male subjects perceived the fashion photographs more attractive than female subjects did.

• 한국의류학회지
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• 제21권4호
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• pp.718-726
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• 1997

The purpose of the study was to investigate the interaction effect of garment formality, Yin -Yang level, and body type of children on impression formation. The experimental materials developed for the study were a set of stimuli (8 color photographs) and a response scale (34 bipolar adjectives) and the subjects were 267 elementary school teachers in Taejon area who were responsible for the first grade students. Results were as follows; The 3 independent variables showed significant effects on impression of the 4 factors (sociability, potency, dynamics, cooperation) of impression. Since body type had interaction effects with garment formality and subject's gender, the two body types were separately analyzed. For the normal body type, only the garment formality affected on impression of cooperation factor But for the large body type, garment formality affected on impression of potency dimension, garment Yin-Yang level affected on social and dynamics dimension, and subject's gender affected on social and cooperation dimensions. The body type was the most salient variables and clothing effects for the large body type was significantly different for the normal body type. It is concluded that the results support the cognitive categorization theory on impression formation.

• Archives of Plastic Surgery
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• 제34권4호
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• pp.493-494
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• 2007

Purpose: Nevus sebaceous is a distinctive growth commonly found on the scalp, forehead and retroauricular region. Nevus sebaceous has age-related changes in morphologic and histologic appearance. Secondary neoplasm including basal cell carcinoma is found in 20% of the nevus sebaceous which were not treated properly. So, we report a case of basal cell carcinoma that is arising in nevus sebaceous but has no malignant appearance. Methods: A 38 year-old female patient wanted to excise the lesion on scalp. It looked like typical nevus sebaceous because we didn't find any malignant appearances. We excised the lesion including minimal normal tissue. Results: After the excision of the lesion, pathologist reported the nevus sebaceous with multifocal basal cell carcinoma. Conclusion: Many patients want to excise the nevus sebaceous that stands out to other people. But they don't know the potency of malignant changes. So, plastic surgeons have to notify the potency and make plan for proper treatment.

• Natural Product Sciences
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• 제25권3호
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• pp.215-221
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• 2019

Inflammation is the crucial biological process of immune system which acts as body's defense and protective response against the injuries or infection. However, the systemic inflammation devotes the adverse effects such as multiple inflammation associated diseases. One of the best ways to treat this entity is by blocking the tumor necrosis factor alpha ($TNF-{\alpha}$) and TNF-related apoptosis-inducing ligand (TRAIL) to avoid the proinflammation cytokines production. Thus, this study aims to evaluate the potency of Sambucus bioactive compounds as anti-inflammation through in silico approach. In order to assess that, molecular docking was performed to evaluate the interaction properties between the $TNF-{\alpha}$ or TRAIL with the ligands. The 2D structure of ligands were retrieved online via PubChem and the 3D protein modeling was done by using SWISS Model. The prediction results of the study showed that caffeic acid (-6.4 kcal/mol) and homovanillic acid (-6.6 kcal/mol) have the greatest binding affinity against the $TNF-{\alpha}$ and TRAIL respectively. This evidence suggests that caffeic acid and homovanillic acid may potent as anti-inflammatory agent against the inflammation associated diseases. Finally, this study needs further examination and evaluation to validate the potency of Sambucus bioactive compounds.

• 동의생리병리학회지
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• 제33권1호
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• pp.63-67
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• 2019

Interaction between epidermis and dermis plays an important role in wound healing and hair follicle formation. This study focused on investigating the potency of ethanol extract of Puerariae Radix (EPR) as cosmetic ingredient using human dermal fibroblasts (hDFn). Our results revealed that EPR suppressed collagenase activity dose-dependently. EPR inhibited activity of $5{\alpha}$-reductase I and II at the final concentration of $25{\mu}g/ml$ in hDFn cells. Also, EPR promoted the proliferation and the ERK activation of cells. ERK phosphorylation by EPR was blocked by specific inhibitor of ERK, PD98059. EPR-induced cell proliferation was blocked by PD98059. This means that EPR could promote the proliferation of hDFn cells via the activation ERK. Collectively, these results suggest that EPR may be used as a new cosmetic ingredient.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.380.2-380.2
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• 2002

Peroxisome proliferator-activated receptor (PPAR)-$\gamma$ is a nuclear hormone receptor family that plays an important role in the transcriptional regulation of genes in cellular lipid and energy metabolism. In our search for Iigands for PPAR-$\gamma$ from natural resources. two phenylpropanoids. 3.4.5-Trimethoxy cinnamylalcohol (1) and 3.4.5- Trimethoxy cinnamaldehyde (2). were isolated as PPAR-$\gamma$ agonists from the MeOH extracts of Zanthoxylum schinifolium Sieb. & ZUCCo (Rutaceae) by activity-guided fractionation. These two compoundS bind and activated PPAR-$\gamma$ transcriptional activity in a dose dependent manner assessed by ligand-binding assay. While the maximum activities for PPAR-$\gamma$ of these compounds were comparable with that of rosiglitazone. which is currently used in the treatment of Type II diabetes. the potency of these compounds were much weaker than rosiglitazone ($ED_{50}$=t.2$\mu\textrm{M}$) with the $ED_{50}$ values of 9.08 and 4.08 $\mu\textrm{M}$. respectively. To examine the structure-activity relationship of phenylpropanoids. we prepared several phenylpropanoid derivatives and measured the activity. We observed that substituents at 4'- position could playa key role in determining the potency for PPAR-$\gamma$ agonistic activity .

• 한국식물병리학회지
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• 제2권2호
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• pp.89-95
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• 1986

쇠비름 즙액에서 얻은 5종의 저급지방산인 isobutyric(C-4), butyric(C-4), isovaleric(C-5), valeric (C-5), caproic(C-6) acids등이 그들 사이에 항균력의 차이는 있었지만 공시한 25종의 식물병원균의 포자발아나 균사생장에 대하여 폭넓은 항균스펙트럼을 보여주었다. 각각의 지방산의 항균력은 포자발아검정이나 균사신장검정에 있어서 공시균주에 따라 큰 차이를 보여주었다. 포자발아검정에 공시한 17종의 병원균과 균사신장검정에 공시한 16종의 병원균은 그들의 포자발아나 균사신장을 제각기 완전히 저해하는 각각의 지방산의 최저저해농도(MIC)에 따라 3군으로 나눌 수 있다. 이밖에도 이 연구의 결과에서 다음과 같은 가설을 제시할 수 있었다. 1) Caproic acid는 공시균의 균사신장보다 포자발아에 대하여 더욱 강한 독성을 보였으나 약간의 예외는 있었지만 그 밖의 지방산은 이와같은 독성을 보여주지 않았다. 2) 지방산의 사슬이 길수록 항균력도 강하다. 3) n-Butyric acid와 n-Valeric acid는 그들의 이성체보다 항균력이 강하다. 4) 각각의 지방산은 부생균의 포자발아나 균사신장에 대한 것보다 활물기생균이나 몇가지 조건적 기생균의 그것들에 대하여 더욱 강한 독성을 보여주었다.