• International Journal of Computer Science & Network Security
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• 제22권10호
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• pp.97-106
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• 2022

Objective. Nanotechnology is spreading among all areas of life, from everyday devices to medicine. The concept of nanotechnology argues that not only can new physical and chemical properties of materials be discovered, but also the new potential of nanostructures when reduced to the nanoscale. The growing interest in the application of nanomaterials in dentistry contributes to the proliferation of the range of nanomaterials used by specialists. The purpose of this review of information sources was to analyze the prospects for the use of nanomaterials in dentistry. Methods. We used the bibliographic semantic method of research, for which we analyzed electronic databases of primary literature sources Scopus, Web of Science, Research Gate, PubMed, MDPI, and MedLine. English-language scientific articles published after 2017 were taken into consideration. Results. According to the results of a search study among modern information primary sources, nanotechnology improves the preventive properties of oral care products, improves the structural-mechanical and aesthetic properties of composite mixtures for dentistry, overcomes the problems of the clinical application of dental implants. Despite the prospects of nanotechnology applications in medicine in general and dentistry in particular, the existing economic and technological problems require a thorough solution for further implementation of nanostructures. Scientific novelty. For the first time, the analysis of modern trends in the application of nanotechnology in dentistry is carried out and the peculiarities of materials are highlighted, the problems and prospects of nanostructures implementation in modern dental implantology are given, physical, chemical, mechanical, and antibacterial properties of nanomaterials are evaluated. The effect of nanomaterials on the microbial adhesion of the tooth or implant surface is described. Practical significance. The presented publication can become a scientific basis for the solution of urgent problems hindering the introduction of nanotechnology into dental practice. Conclusions. Thus, the use of nanostructures opens up great opportunities for the treatment of a wide range of diseases, not only of dental nature but also in medicine in general.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권6호
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• pp.500-509
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• 2022

Purpose: We compared the health-related quality of life (HRQOL) of children and adolescents with functional abdominal pain disorders (FAPDs) and organic abdominal pain disorders (ORGDs). Methods: This was a single-center, cross-sectional, observational study. The PedsQL 4.0 generic cores scales parent proxy-report was administered to parents/caregivers of 130 and 56 pediatric patients with FAPDs and ORGDs respectively on their first visit. The self-reported pain intensity in the patients was assessed using a visual analog scale (VAS) and facial affective scale (FAS). Results: Irritable bowel syndrome was the most prevalent FAPDs, and the most prevalent ORGDs were reflux esophagitis (41.1%) and gastritis associated with Helicobacter pylori (21.4%). There was no difference in HRQOL among patients diagnosed with ORGDs and FAPDs (p>0.05). Patients with ORGDs and FAPDs had lower HRQOL Scale scores than healthy Brazilian and American children's references, with a high proportion of children at risk for impaired HRQOL (p<0.0001). There was no difference in the VAS and the FAS scores between the ORGDs and the FAPDs. FAPDs had a higher prevalence of girls' and couples' disagreement (p<0.02), although poor school performance (p<0.0007) and bullying (p<0.01) were higher in patients with ORGD. Conclusion: This study revealed that there was a difference in impaired HRQOL between patients with ORGDs and FAPDs. Thus, considering the high prevalence of chronic abdominal pain in children, a well-founded treatment plan is necessary for a multidisciplinary cognitive-behavioral Pain management program.

• Imaging Science in Dentistry
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• 제53권1호
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• pp.43-51
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• 2023

Purpose: This study aimed to assess texture analysis(TA) of cone-beam computed tomography (CBCT) images as a quantitative tool for the differential diagnosis of odontogenic and non-odontogenic maxillary sinusitis(OS and NOS, respectively). Materials and Methods: CBCT images of 40 patients diagnosed with OS (N=20) and NOS (N=20) were evaluated. The gray level co-occurrence (GLCM) matrix parameters, and gray level run length matrix texture (GLRLM) parameters were extracted using manually placed regions of interest on lesion images. Seven texture parameters were calculated using GLCM and 4 parameters using GLRLM. The Mann-Whitney test was used for comparisons between the groups, and the Levene test was performed to confirm the homogeneity of variance (α=5%). Results: The results showed statistically significant differences(P<0.05) between the OS and NOS patients regarding 3 TA parameters. NOS patients presented higher values for contrast, while OS patients presented higher values for correlation and inverse difference moment. Greater textural homogeneity was observed in the OS patients than in the NOS patients, with statistically significant differences in standard deviations between the groups for correlation, sum of squares, sum of entropy, and entropy. Conclusion: TA enabled quantitative differentiation between OS and NOS on CBCT images by using the parameters of contrast, correlation, and inverse difference moment.

• Imaging Science in Dentistry
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• 제53권2호
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• pp.109-115
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• 2023

Purpose: The aim of this study was to evaluate changes in the trabecular bone through texture analysis and compare the texture analysis characteristics of different areas in patients with medication-related osteonecrosis of the jaw (MRONJ). Materials and Methods: Cone-beam computed tomographic images of 16 patients diagnosed with MRONJ were used. In sagittal images, 3 regions were chosen: active osteonecrosis(AO); intermediate tissue (IT), which presented a zone of apparently healthy tissue adjacent to the AO area; and healthy bone tissue (HT) (control area). Texture analysis was performed evaluating 7 parameters: secondary angular momentum, contrast, correlation, sum of squares, inverse moment of difference, sum of entropies, and entropy. Data were analyzed using the Kruskal-Wallis test with a significance level of 5%. Results: Comparing the areas of AO, IT, and HT, significant differences (P<0.05) were observed. The IT and AO area images showed higher values for parameters such as contrast, entropy, and secondary angular momentum than the HT area, indicating greater disorder in these tissues. Conclusion: Through texture analysis, changes in the bone pattern could be observed in areas of osteonecrosis. The texture analysis demonstrated that areas visually identified and classified as IT still had necrotic tissue, thereby increasing the accuracy of delimiting the real extension of MRONJ.

• 한국엔터테인먼트산업학회논문지
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• 제13권5호
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• pp.59-65
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• 2019

가상현실 콘텐츠 산업의 성장 측면에서 반드시 해결해야 할 중요한 과제인 사이버 멀미의 감소는 산업계는 물론 학계에서도 많은 관심의 대상이다. 하지만 사이버 멀미 현상에 대한 오랜 관심과 연구에도 불구하고 해결책은 미흡한 실정이다. 본 논문에서는 사용자가 몰입형 가상현실을 체험할 때 사이버 멀미를 효과적으로 측정할 수 있는 도구를 개발하여 사이버 멀미를 감소시킬 수 있는 방안을 마련함을 목적으로 한다. 먼저 선행 연구에서 사용한 사이버 멀미 측정 방법에서 사이버 멀미에 관련된 공통적인 요인을 분석하여 각각 하위 요소들로 도출하였다. 이를 토대로 몰입형 가상현실에서 효과적인 사이버 멀미 측정 평가 도구 모델을 제시하고자한다. 해당 평가 도구 모델을 사이버 멀미 감소는 물론 연구에 참고 되었으면 한다.

• Imaging Science in Dentistry
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• 제53권4호
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• pp.303-312
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• 2023

Purpose: This study investigated the prevalence of developmental and acquired pathologic conditions associated with impacted third molars (3Ms) in a Southern Brazilian population and evaluated whether demographic and tooth characteristics were correlated with the presence of bone or tooth lesions. Materials and Methods: Panoramic radiographs were assessed for developmental (bone-related) or acquired (tooth-related) pathoses associated with impacted upper or lower 3Ms. Data on tooth positioning, tooth development, and patient demographics were collected. A trained, calibrated postgraduate student evaluated all images. Binary and multivariate logistic regression models were used to assess associations between outcomes and the demographic and radiographic variables. The threshold for statistical significance was set at 5% (P<0.05). Results: The sample comprised panoramic radiographs from 2054 patients, predominantly female (59.2%), with a mean age of 27.2±11.5 years. Overall, 4066 impacted 3Ms were evaluated, revealing 471 (11.6%) developmental and 710 (17.5%) acquired pathoses. Among the developmental pathoses, 460 (95.2%) were indicative of dentigerous cysts. Male sex, lower 3M location, vertical or distoangular positioning, and incomplete root formation were associated with an elevated likelihood of developmental pathology. Lower tooth position, complete root formation, and partial eruption were linked to an increased probability of an acquired pathology in the third or second molar. Conclusion: The prevalence of pathologic conditions associated with impacted 3Ms was low. Male sex, lower 3M placement, horizontal or distoangular positioning, and incomplete root formation were associated with developmental pathoses, while lower tooth position, complete root formation, and partial eruption were related to acquired pathoses.

• 한국간호교육학회지
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• 제30권2호
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• pp.101-112
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• 2024

Purpose: The study aimed to examine doctoral students' degree acquisition paths and postgraduate research achievements and explore whether there are differences in the research achievements of doctoral degree holders in relation to the dissertation format. Methods: This study is a retrospective cohort study of nursing doctoral graduates whose degree conferral dates were between August 2013 and August 2023 that compared two dissertation tracks: traditional and publication. We evaluated the proportion of graduates in each track, publication of their dissertations, time to graduation, and the number of peer-reviewed journal publications after graduation. Results: Of the sample, 160 (87.4%) graduated in the traditional track, with only 56 (35.0%) of them publishing their dissertations after graduation. Excluding dissertations, 114 of the graduates (71.3%) published first-authored articles in the traditional track, while 12 (52.2%) did so in the publication track. The time to graduation was significantly shorter in the traditional track, with an average of 5.47±2.45 years, compared to 6.61±2.57 years in the publication track (z=2.26, p=.023). In the traditional track, 64 of graduates (40.0%) majored in adult health nursing, whereas in the publication track, 8 (34.8%) studied community health nursing. Conclusion: This study emphasizes the significance of the publication track for nursing doctoral dissertations in terms of research dissemination. Despite its numerous advantages, it is not yet the preferred choice for both students and faculty. Maintaining the publication track as an additional graduation option is worthwhile, as it allows students to gain research publishing experience before graduation and to effectively disseminate scientific findings in nursing.

• International Journal of Knowledge Content Development & Technology
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• 제14권3호
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• pp.39-57
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• 2024

Plagiarism detection software is beneficial in detecting plagiarism in research works of postgraduate students. Despite the benefits of using plagiarism detection software, studies have revealed that most students, including postgraduates, do not use plagiarism detection software as expected. This could depend on the provision of facilitating conditions like internet connectivity, training opportunities and electricity. Thus, this study examined facilitating conditions and the use of plagiarism detection software among postgraduates of the University of Ibadan, Nigeria. A descriptive survey research design of the correlational type was used for this study, with a population of 2143 postgraduates. The multi-stage random sampling technique was used to determine the sample size of 242. The questionnaire was the research instrument, and data was analysed using descriptive statistics. Results showed that most postgraduates agreed that the university provided facilitating conditions like internet connectivity. The majority of the respondents noted that they used Turnitin monthly. Most of the respondents noted that they used plagiarism detection software to paraphrase their work and check the correctness of the grammar in their documents. The most prominent challenges confronting plagiarism detection software use by most respondents were their inability to afford subscription payment to use the plagiarism detection software and slow internet connectivity. There was a significant positive relationship between facilitating conditions and the use of plagiarism detection software by the postgraduates of the University of Ibadan, Nigeria. Some of the recommendations for the institution's management include leveraging the vast network of alumni willing to give back to the institution and intervening in the provision of internet connectivity and electricity.

• Imaging Science in Dentistry
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• 제54권1호
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• pp.1-11
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• 2024

Purpose: This study was conducted to investigate the safety of dental imaging in pregnant women with respect to fetal health. Materials and Methods: Searches were conducted of the PubMed, Scopus, and Web of Science databases in May 2023. The inclusion criteria encompassed cross-sectional and longitudinal studies that focused on the analysis of diagnostic dental imaging in pregnant women, as well as studies utilizing phantoms to simulate imaging examinations. The exclusion criteria consisted of reviews, letters to the editor, book chapters, and abstracts from scientific conferences and seminars. Results: A total of 3,913 articles were identified. Based on a review of the titles and abstracts, 3,892 articles were excluded, leaving 21 articles remaining for full-text review. Of these, 18 were excluded, and 4 additional articles were included as cross-references. Ultimately, 7 articles underwent quantitative-qualitative analysis. Three retrospective studies were focused on pregnant women who underwent dental imaging procedures. The remaining 4 studies utilized female phantoms to simulate imaging examinations and represent the radiation doses absorbed by the uterus or thyroid. Conclusion: Few dental radiology studies have been conducted to determine the safe radiation threshold for pregnant women. Additionally, the reviewed articles did not provide numbers of dental examinations, by type, corresponding to this dose. Dental imaging examinations of pregnant women should not be restricted if clinically indicated. Ultimately, practitioners must be able to justify the examination and should adhere to the "as low as diagnostically acceptable, being indication-oriented and patient-specific" (ALADAIP) principle of radioprotection.

• Anatomy and Cell Biology
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• 제57권2호
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• pp.256-270
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• 2024

The antidepressant drug trazodone (TRZ) is commonly used for treating depression, anxiety, and insomnia, however, it causes cardiotoxicity, which is one of its limitations. The objective of this work was to investigate the impact of sage (Salvia officinalis) in rats against cardiotoxicity induced by TRZ and to investigate the mechanisms involved in its cardio-protective properties through autophagy and oxidative stress. Fifty male albino rats were split randomly into five experimental groups: control group, sage oil group (100 mg/kg), TRZ group (20 mg/kg), protective group, and curative group. Cardiac function biomarkers (aspartate aminotransferase [AST], creatine kinase-MB [CK-MB], and cardiac troponin T [cTnI]) were assessed in serum. Oxidative stress and inflammatory biomarkers in cardiac tissue (total antioxidant capacity, malondialdehyde, and tumor necrosis factor-α) were evaluated. Heart tissues were subjected to histological, immunohistochemical, and ultrastructural evaluations. DNA damage also evaluated. Significant rise in the levels of AST, CK-MB, and cTnI were observed with enhanced autophagy along with marked histopathological changes in the form of interrupted muscle fibers with wide interstitial spaces with areas of hemorrhage and extravasated blood and interstitial mononuclear cellular infiltration in TRZ group. DNA damage was also significantly increased in TRZ group. However, administration of sage in both protective and curative groups show marked improvement of the cardiac alterations. In conclusion, sage ameliorated the alterations in the heart induced by trazadone through modulation of autophagy and oxidative stress.