• Title/Summary/Keyword: Population regulation

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Problems of Employment of the Population and Directions of Their Regulation in the Conditions of War

  • Zakharchyn, Galyna;Antonov, Andriі;Voityk, Oleksandra;Plotka, Lyubov;Mirko, Nataliia
    • International Journal of Computer Science & Network Security
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    • v.22 no.11
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    • pp.303-307
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    • 2022
  • The purpose of the study is to determine the key aspects of the problems of employment of the population and the directions of their state regulation in war conditions. Employment policy involves a system of measures to create conditions for a more complete use of the potential of labor and business activity of the able-bodied population, linking this activity through taking into account the specifics of group interests with the tasks and guidelines for socio-economic development. But in the conditions of war, this problem acquires a new relevance. For the study, a number of theoretical methods of analysis were used. Based on the results of the study, the key aspects of the problems of employment of the population and the directions of their state regulation in war conditions were identified.

Whole-genome resequencing reveals domestication and signatures of selection in Ujimqin, Sunit, and Wu Ranke Mongolian sheep breeds

  • Wang, Hanning;Zhong, Liang;Dong, Yanbing;Meng, Lingbo;Ji, Cheng;Luo, Hui;Fu, Mengrong;Qi, Zhi;Mi, Lan
    • Animal Bioscience
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    • v.35 no.9
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    • pp.1303-1313
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    • 2022
  • Objective: The current study aimed to perform whole-genome resequencing of Chinese indigenous Mongolian sheep breeds including Ujimqin, Sunit, and Wu Ranke sheep breeds (UJMQ, SNT, WRK) and deeply analyze genetic variation, population structure, domestication, and selection for domestication traits among these Mongolian sheep breeds. Methods: Blood samples were collected from a total of 60 individuals comprising 20 WRK, 20 UJMQ, and 20 SNT. For genome sequencing, about 1.5 ㎍ of genomic DNA was used for library construction with an insert size of about 350 bp. Pair-end sequencing were performed on Illumina NovaSeq platform, with the read length of 150 bp at each end. We then investigated the domestication and signatures of selection in these sheep breeds. Results: According to the population and demographic analyses, WRK and SNT populations were very similar, which were different from UJMQ populations. Genome wide association study identified 468 and 779 significant loci from SNT vs UJMQ, and UJMQ vs WRK, respectively. However, only 3 loci were identified from SNT vs WRK. Genomic comparison and selective sweep analysis among these sheep breeds suggested that genes associated with regulation of secretion, metabolic pathways including estrogen metabolism and amino acid metabolism, and neuron development have undergone strong selection during domestication. Conclusion: Our findings will facilitate the understanding of Chinese indigenous Mongolian sheep breeds domestication and selection for complex traits and provide a valuable genomic resource for future studies of sheep and other domestic animal breeding.

A Field Study attention: The Population Density in Resident Area and Evacuation Regulation on Sale Facility(II) (대형 판매시설물의 피난안전규정을 위한 재실자 밀도에 관한 현장조사 연구(II))

  • Lee, Sang-Hee;Seo, Dong-Goo;Hwang, Eun-Kyung;Hwang, Keum-Sook;Kwon, Young-Jin
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 2008.04a
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    • pp.273-276
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    • 2008
  • As the rapid and various changing of social aspects, the structures are getting bigger, higher and more complex. The importance of evacuation is on the rise as increased using frequency of multiplex sale facility and it's high population density. According to the result of a survey with 4 domestic wholesales mart's population density, the average and maximum was 0.41(人/$m^2$) and 0.46(人/$m^2$). considering evacuation dangerousness, the maximum value will be suitable for computation of evacuation capacity and this will be submitted as a basic data for computation of evacuation capacity.

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Association of Hepatocyte Nuclear Factor-$4{\alpha}$ (HNF-$4{\alpha}$) Polymorphisms (rs1884614) with Type 2 Diabetes in Korean Population

  • Kim, Su-Won;Yoo, Min
    • Biomedical Science Letters
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    • v.15 no.1
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    • pp.101-103
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    • 2009
  • The hepatocyte nuclear factor-$4{\alpha}$ (HNF-$4{\alpha}$), transcription factor involved in the regulation of serum lipid and glucose levels, has recently been reported to be associated with type 2 diabetes. Therefore, we investigated the genotype for the rs1884614 of HNF-$4{\alpha}$ gene in Korean population and compared genotype of patients with control group. 100 patients (Male 63, Female 37), who previously underwent type 2 diabetes (T2DM) and 100 controls (Male 36, Female 64) participated in this study. According to our present study there was no association between rs1884614 polymorphism in HNF-$4{\alpha}$ gene and T2DM in Koreans although other reports showed that HNF-$4{\alpha}$ polymorphisms might be associated with the pathogenesis of T2DM in Pima Indians et al. We assume that this finding should contribute to understanding of type 2 diabetes in Korean population in detail at genetic level.

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Some Considerations on the Population Regulation of the Green Rice Leafhopper, Nephotettix cincticeps Uhler (끝동매미충 개체군의 밀도조절에 관여하는 몇가지 요인에 관한 연구)

  • Kim S.S.;Hyun J.S.
    • Korean journal of applied entomology
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    • v.18 no.1 s.38
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    • pp.15-21
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    • 1979
  • To determine the population regulation mechanism of the Green rice leafhopper (Nephotettix cincticeps Uhler), the responses of the population increase to initial densities and the effect of host conditions and temperatures during developmental period were investigated. In the out door experiment, the increasing ratio of population density of this pest was reduced as initial density increased and this density-dependent effect was differ in accordance with host condition. Host conditioning through feeding resulted in reduction in numbers of eggs produced and it seemed to be affected by some inhibiting materials secreted by the pest during feeding. though the direct effect of feeding can't be excluded. The population growth was related with population density and host stage. Thus in late planted units, the host stage was favourable to the growth of population at low initial insect density but unfavourable at relatively high initial insect density and in early planted units, vice versa. The temperature during developmental stages definitely affected the determination of sex ratio of adult population and reduced numbers of eggs produced. The most favourable temperature to the population increase was $290^{\circ}C$, and at high temperature, $33^{\circ}C$, severe reduction of fecundity was shown ana it seemed to be caused by the simple reduction in numbers of eggs produced.

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The Analysis of Environmental Protection Sector and Regulation Resistance -A Study on Pyeongchang- (환경규제 지역과 규제저항 분석 - 평창을 사례로 -)

  • Bae, Sun-Hak
    • Journal of the Korean Geographical Society
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    • v.41 no.6 s.117
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    • pp.701-713
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    • 2006
  • This study considers the case when a district with a high development possibility is set up as a regulation region. Initial assumption is that there would be regulation resistance in and around the regulation region. Pyeongchang is taken as a study areas, performing necessary analysis of environment regulation and regulation resistance based upon spatial analysis with the use of GIS. The research proceeding steps are as follows. After examining Pyeongchang present environment regulation state, environment regulation map is constructed, and classification of Pyeongchang's relatively development possibility level map is made. Using this regulation map and development possibility level map, relative regulation resistance level is measured. The results that the rates of Pyeongchang environment regulation region in its present state was higher than Namhan river basin's regulation region rates. Also, overlapping a high development possibility level region with an environment regulation region, the analysis results give reasons to expect high level of regulation resistance in Doam-myeon and Jinbu-myeon in small town units. The analysis of Pyeongchang new buildings locations with regard to environment regulation showed intensive distribution in the regulation region with high development possibility level and adjacent areas (about 66% of new buildings are distributed within 500m range from regulation region). Such results show that the local administration and existing environment regulation policy, not capable of offering direct benefit to the population, are having immanent problems in environment sustainable development and connected with it environment harm causation.

Suggestions for Improvement of Youth Internet Regulation: Focusing on Youth Internet Regulation of the Major Country (청소년 인터넷규제 개선방향에 대한 제언: 주요국의 청소년 인터넷규제를 중심으로)

  • Song, Eun-Ji
    • The Journal of the Korea Contents Association
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    • v.13 no.11
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    • pp.690-698
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    • 2013
  • Advanced digital environment, ease of life would bring significant benefits, but rather indiscriminate access to information have occurred new social problems. Especially the youth and children using the Internet to increase in population resulting from harmful information on the Internet, concerns about the negative impact increases establish policies for the protection of youth and children emphasizes the importance of various activities international community. Despite major countries aim to self-regulation minimize the direct regulation through collaboration with the private sector cultivation and campaign, continuing education, Korea was analyzed that implement direct and coercive enforcement regulations such as 'internet game shut down' and insufficient social infrastructure to create activities. Therefore, in order to create a positive internet environment, self-regulation is essential with private experts and organizations based on cooperation and indirect regulation.

Establishment of the Measurement Model about the Adequate Urban Development Density using System Dynamics (시스템다이내믹스를 활용한 도시개발밀도의 적정성 평가 모델 구축 연구)

  • 전유신;문태훈
    • Proceedings of the Korean System Dynamics Society
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    • 2003.08a
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    • pp.1-24
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    • 2003
  • The purpose of this paper was developing a development density control model for urban growth management, using system dynamics modeling. The density control model was developed to see how urban growth, transition, and decay occur depending on the interaction among population, houses, industry structure, land and urban infrastructure such as road, water supply, and sewage treatment facilities. Suggesting adequate level of development density control using the model was another purpose of this paper. The model was applied to An'yang city to estimate the maximum number of population, industry structures, houses, and cars that can be adequately sustained with the current An'yang city's infrastructur capacity. The computer simulation results shows that the city is overpopulated by some 90,000 people. To reduce the population to the adequate level that the current urban infrastructure can sustain, the current city regulation on floor area ratio are needed to be strengthened at least 20 to 35%.

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Derivation of MSC Like-Cell Population from Feeder Free Cultured hESC and Their Proteomic Analysis for Comparison Study with BM-MSC (Feeder Free 상태에서 배양된 인간 배아 줄기세포를 이용한 중간엽 줄기세포 분화 및 단백체학을 이용한 골수 유래 중간엽 줄기세포와의 비교)

  • Park, Soon-Jung;Jeon, Young-Joo;Kim, Ju-Mi;Shin, Jeong-Min;Chae, Jung-Il;Chung, Hyung-Min
    • Reproductive and Developmental Biology
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    • v.34 no.3
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    • pp.143-151
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    • 2010
  • Pluripotency of human embryonic stem cell (hESC) is one of the most valuable ability of hESCs for applying cell therapy field, but also showing side effect, for example teratoma formation. When transplant multipotent stem cell, such as mesnchymal stem cell (MSC) which retains similar differentiation ability, they do not form teratoma in vivo, but there exist limitation of cellular source supply. Accordingly, differentiation of hESC into MSC will be promising cellular source with strong points of both hESC and MSC line. In this study, we described the derivation of MSC like cell population from feeder free cultured hESC (hESC-MSC) using direct differentiation system. Cells population, hESC-MSC and bone marrow derived MSC (BM-MSC) retained similar characteristics in vitro, such as morphology, MSC specific marker expression and differentiation capacity. At the point of differentiation of both cell populations, differentiation rate was slower in hESC-MSC than BM-MSC. As these reason, to verify differentially expressed molecular condition of both cell population which bring out different differentiation rate, we compare the molecular condition of hESC-MSC and BM-MSC using 2-D proteomic analysis tool. In the proteomic analysis, we identified 49 differentially expressed proteins in hESC-MSC and BM-MSC, and they involved in different biological process such as positive regulation of molecular function, biological process, cellular metabolic process, nitrogen compound metabolic process, macromolecule metabolic process, metabolic process, molecular function, and positive regulation of molecular function and regulation of ubiquitin protein ligase activity during mitotic cell cycle, cellular response to stress, and RNA localization. As the related function of differentially expressed proteins, we sought to these proteins were key regulators which contribute to their differentiation rate, developmental process and cell proliferation. Our results suggest that the expressions of these proteins between the hESC-MSC and BM-MSC, could give to us further evidence for hESC differentiation into the mesenchymal stem cell is associated with a differentiation factor. As the initial step to understand fundamental difference of hESC-MSC and BM-MSC, we sought to investigate different protein expression profile. And the grafting of hESC differentiation into MSC and their comparative proteomic analysis will be positively contribute to cell therapy without cellular source limitation, also with exact background of their molecular condition.

Haussmann's Urban Green Space System in Paris' The Efficacities and the Logic of the Green Politics (오스만의 파리시 도심녹지시스템 : 그 효용성과 녹지정책의 논리)

  • 견진현
    • Journal of the Korean Institute of Landscape Architecture
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    • v.31 no.4
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    • pp.1-12
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    • 2003
  • The urban park provides a safe rest and leisure area, and offers the beauty of nature to counter the drearyness of urban space. It can provide benefits such as the reduction of environmental pollution, the regulation of the local climate, and it can also provide a safe area during times of disaster. However, there was no interest in urban park development and control in Korea during the economic boom of the mid 1960s. Furthermore, during the industrialization process, the population grew significantly in the cities and the cities' scales were noticeably extended; as a result of this, the living environment and the natural environment in the cities worsened. With rapid urbanization and industrialization, urban green area diminished, and it became necessary to organize the urban park system to improve quality of life. 45% of south korea's population lives in 6 cities, which is only 4% of Korea's land size. The Urban park system has to be considered in the urban planning process. Paris' urban green system can be a role-model for Korea's urban green development plan to function organically. Urban public park concepts have been used in Paris's urban planning since 1850. There were hardly any parks, gardens and squares for the public before the middle of the 19th century. For improving life-styles for the poor, Napoleon III strongly supported the development of green space systems in Paris by G.E. Haussmann. Napoleon III and Haussmann established and applied the urban green regulation within Paris urban planning. The purpose of this study is to investigate the green regulations Haussmann's Paris urban plan and urban green space system: and as a result of this, it can be an indicator for urban green space development in Korea.