• International Journal of Computer Science & Network Security
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• 제22권11호
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• pp.303-307
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• 2022

The purpose of the study is to determine the key aspects of the problems of employment of the population and the directions of their state regulation in war conditions. Employment policy involves a system of measures to create conditions for a more complete use of the potential of labor and business activity of the able-bodied population, linking this activity through taking into account the specifics of group interests with the tasks and guidelines for socio-economic development. But in the conditions of war, this problem acquires a new relevance. For the study, a number of theoretical methods of analysis were used. Based on the results of the study, the key aspects of the problems of employment of the population and the directions of their state regulation in war conditions were identified.

• Animal Bioscience
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• 제35권9호
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• pp.1303-1313
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• 2022

Objective: The current study aimed to perform whole-genome resequencing of Chinese indigenous Mongolian sheep breeds including Ujimqin, Sunit, and Wu Ranke sheep breeds (UJMQ, SNT, WRK) and deeply analyze genetic variation, population structure, domestication, and selection for domestication traits among these Mongolian sheep breeds. Methods: Blood samples were collected from a total of 60 individuals comprising 20 WRK, 20 UJMQ, and 20 SNT. For genome sequencing, about 1.5 ㎍ of genomic DNA was used for library construction with an insert size of about 350 bp. Pair-end sequencing were performed on Illumina NovaSeq platform, with the read length of 150 bp at each end. We then investigated the domestication and signatures of selection in these sheep breeds. Results: According to the population and demographic analyses, WRK and SNT populations were very similar, which were different from UJMQ populations. Genome wide association study identified 468 and 779 significant loci from SNT vs UJMQ, and UJMQ vs WRK, respectively. However, only 3 loci were identified from SNT vs WRK. Genomic comparison and selective sweep analysis among these sheep breeds suggested that genes associated with regulation of secretion, metabolic pathways including estrogen metabolism and amino acid metabolism, and neuron development have undergone strong selection during domestication. Conclusion: Our findings will facilitate the understanding of Chinese indigenous Mongolian sheep breeds domestication and selection for complex traits and provide a valuable genomic resource for future studies of sheep and other domestic animal breeding.

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2008년도 춘계학술논문발표회 논문집
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• pp.273-276
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• 2008

As the rapid and various changing of social aspects, the structures are getting bigger, higher and more complex. The importance of evacuation is on the rise as increased using frequency of multiplex sale facility and it's high population density. According to the result of a survey with 4 domestic wholesales mart's population density, the average and maximum was 0.41(人/$m^2$) and 0.46(人/$m^2$). considering evacuation dangerousness, the maximum value will be suitable for computation of evacuation capacity and this will be submitted as a basic data for computation of evacuation capacity.

• 대한의생명과학회지
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• 제15권1호
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• pp.101-103
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• 2009

The hepatocyte nuclear factor-$4{\alpha}$ (HNF-$4{\alpha}$), transcription factor involved in the regulation of serum lipid and glucose levels, has recently been reported to be associated with type 2 diabetes. Therefore, we investigated the genotype for the rs1884614 of HNF-$4{\alpha}$ gene in Korean population and compared genotype of patients with control group. 100 patients (Male 63, Female 37), who previously underwent type 2 diabetes (T2DM) and 100 controls (Male 36, Female 64) participated in this study. According to our present study there was no association between rs1884614 polymorphism in HNF-$4{\alpha}$ gene and T2DM in Koreans although other reports showed that HNF-$4{\alpha}$ polymorphisms might be associated with the pathogenesis of T2DM in Pima Indians et al. We assume that this finding should contribute to understanding of type 2 diabetes in Korean population in detail at genetic level.

• 한국응용곤충학회지
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• 제18권1호
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• pp.15-21
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• 1979

끝동매미충(Nephotettix cincticeps Uhler) 개체군의 초기밀도, 기주식물의 생육상태, 온도 그리고 기주의 조건화가 개체군증가에 미치는 영향을 조사하여 다음과 같은 결론을 얻었다. 1. 야외 Pot시험에서 이 해충의 개체군밀도 증가율은 접종한 개체수의 증가에 따라 감소하며 이러한 밀도의존적 작용은 기주식물의 생육상태에 따라 차가 있었다. 2. 흡즙에 의한 기주의 조건화는 성충의 산란수를 감소시켰으며 이것은 흡즙중에 분필되는 산난억제물질에 의한 것으로 생각되나 흡즙에 의한 직접적인 영향을 전연 배제할 수는 없을 것으로 생각된다. 3. 개체군의 밀도와 기주식물의 생육상태는 개체군의 생장에 있어서 복합적인 관련성을 갖고 있어서 만식구의 경우 기주의 생육상태는 조식구에 비해 낮은 충밀도에서는 개체군의 생장에 유리하였으나 높은 충밀도에서는 불리해졌다. 4. 약충생육기의 고온은 산난수를 감소시키고 약충기 치사율을 증대시피며 성충개체군의 성비에 명백한 영향을 미친다. 5. 생육기간중 개체군의 증식에 가장 유리한 온도는 $29^{\circ}C$였으며 $33^{\circ}C$의 고온에서는 우화율이 낮고 성충의 산란력에 장해를 주어서 산란수가 적었다.

• 대한지리학회지
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• 제41권6호
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• pp.701-713
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• 2006

이 연구는 개발가능성이 높은 지역이 규제지역으로 설정되어 있을 때 규제지역과 규제지역의 주변으로 규제저항이 발생할 것이라는 전제에서 출발한다. 그리고 이에 대한 분석은 GIS를 활용한 공간분석 방법으로 수행하였으며, 평창을 연구지역으로 하였다. 평창의 환경관련 규제현황을 조사하여 환경규제지도를 제작하고, 평창지역 전체의 상대적 개발 가능성 정도를 등급화 하였다. 그리고 이렇게 제작된 규제지도와 개발가능성등급도를 이용하여 상대적인 규제저항 정도를 측정하였다. 그 결과 평창의 환경관련 규제 비율은 남한강 유역권 전체의 규제 비율 보다 높게 나타났으며, 개발 가능성이 높은 지역과 환경 규제지역을 중첩하여 분석한 결과 읍면단위에서는 도암면과 진부면의 규제저항이 높을 것으로 예상되었다. 그리고 평창의 신규건물(1999년 $\sim$ 2005년) 입지와 환경규제와의 관계를 분석한 결과 개발가능성 등급이 높고 규제지역과 인접한 지역에 집중적으로 분포(신규건물의 약 66%가 규제지역으로부터 500m 이내 지역에 분포)하였다. 이러한 결과로 볼 때 지방정부와 주민에게 직접적인 이익을 제공하지 못하는 규제권역 설정 위주의 환경정책은 난 개발과 그에 따른 환경파괴라는 내재된 문제를 지니고 있음을 보여주는 것이다.

• 한국콘텐츠학회논문지
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• 제13권11호
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• pp.690-698
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• 2013

발전된 디지털 환경은 생활 편의성 향상 측면에서 상당한 이점을 가져다주고 있지만, 무분별한 정보의 접근은 오히려 새로운 사회 문제를 발생시키고 있다. 특히 청소년이나 어린이 인터넷 이용 인구의 증가로 인터넷 상의 유해 정보로부터 야기되는 부정적인 영향에 대한 우려가 높아짐에 따라, 국제 사회에서는 인터넷 상의 청소년 및 어린이 보호를 위한 정책 마련과 각종 활동의 중요성이 강조되고 있다. 본고에서는 이와 같은 추세를 반영해 해외 주요 국가의 청소년 보호를 위한 인터넷 규제 및 운영 현황을 살펴보고 향후 국내에서 청소년 보호를 위한 인터넷 환경 강화에 필요한 요건을 도출해본다. 주요 국가들은 민간단체들과 긴밀한 협력 구조 구축과 캠페인, 지속적인 교육 등을 통해 자율적인 규제를 유도하며 직접적인 규제를 최소화 하고 있음에도 불구하고, 한국은 인터넷 게임 셧다운제와 같은 직접적이고 강압적인 규제를 시행하고 있으며 사회 인프라 조성 활동도 미흡한 것으로 분석되었다. 따라서, 바람직한 인터넷 환경을 조성하기 위해서는 민간 전문가 및 민간단체 등의 협력 증진과 간접적 규제 기반 조성으로 자율적인 규제를 지향하는 것이 필요하다.

• 한국시스템다이내믹스학회:학술대회논문집
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• 한국시스템다이내믹스학회 2003년도 하계학술대회발표논문집
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• pp.1-24
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• 2003

The purpose of this paper was developing a development density control model for urban growth management, using system dynamics modeling. The density control model was developed to see how urban growth, transition, and decay occur depending on the interaction among population, houses, industry structure, land and urban infrastructure such as road, water supply, and sewage treatment facilities. Suggesting adequate level of development density control using the model was another purpose of this paper. The model was applied to An'yang city to estimate the maximum number of population, industry structures, houses, and cars that can be adequately sustained with the current An'yang city's infrastructur capacity. The computer simulation results shows that the city is overpopulated by some 90,000 people. To reduce the population to the adequate level that the current urban infrastructure can sustain, the current city regulation on floor area ratio are needed to be strengthened at least 20 to 35%.

• Reproductive and Developmental Biology
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• 제34권3호
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• pp.143-151
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• 2010

Pluripotency of human embryonic stem cell (hESC) is one of the most valuable ability of hESCs for applying cell therapy field, but also showing side effect, for example teratoma formation. When transplant multipotent stem cell, such as mesnchymal stem cell (MSC) which retains similar differentiation ability, they do not form teratoma in vivo, but there exist limitation of cellular source supply. Accordingly, differentiation of hESC into MSC will be promising cellular source with strong points of both hESC and MSC line. In this study, we described the derivation of MSC like cell population from feeder free cultured hESC (hESC-MSC) using direct differentiation system. Cells population, hESC-MSC and bone marrow derived MSC (BM-MSC) retained similar characteristics in vitro, such as morphology, MSC specific marker expression and differentiation capacity. At the point of differentiation of both cell populations, differentiation rate was slower in hESC-MSC than BM-MSC. As these reason, to verify differentially expressed molecular condition of both cell population which bring out different differentiation rate, we compare the molecular condition of hESC-MSC and BM-MSC using 2-D proteomic analysis tool. In the proteomic analysis, we identified 49 differentially expressed proteins in hESC-MSC and BM-MSC, and they involved in different biological process such as positive regulation of molecular function, biological process, cellular metabolic process, nitrogen compound metabolic process, macromolecule metabolic process, metabolic process, molecular function, and positive regulation of molecular function and regulation of ubiquitin protein ligase activity during mitotic cell cycle, cellular response to stress, and RNA localization. As the related function of differentially expressed proteins, we sought to these proteins were key regulators which contribute to their differentiation rate, developmental process and cell proliferation. Our results suggest that the expressions of these proteins between the hESC-MSC and BM-MSC, could give to us further evidence for hESC differentiation into the mesenchymal stem cell is associated with a differentiation factor. As the initial step to understand fundamental difference of hESC-MSC and BM-MSC, we sought to investigate different protein expression profile. And the grafting of hESC differentiation into MSC and their comparative proteomic analysis will be positively contribute to cell therapy without cellular source limitation, also with exact background of their molecular condition.

• 한국조경학회지
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• 제31권4호
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• pp.1-12
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• 2003

The urban park provides a safe rest and leisure area, and offers the beauty of nature to counter the drearyness of urban space. It can provide benefits such as the reduction of environmental pollution, the regulation of the local climate, and it can also provide a safe area during times of disaster. However, there was no interest in urban park development and control in Korea during the economic boom of the mid 1960s. Furthermore, during the industrialization process, the population grew significantly in the cities and the cities' scales were noticeably extended; as a result of this, the living environment and the natural environment in the cities worsened. With rapid urbanization and industrialization, urban green area diminished, and it became necessary to organize the urban park system to improve quality of life. 45% of south korea's population lives in 6 cities, which is only 4% of Korea's land size. The Urban park system has to be considered in the urban planning process. Paris' urban green system can be a role-model for Korea's urban green development plan to function organically. Urban public park concepts have been used in Paris's urban planning since 1850. There were hardly any parks, gardens and squares for the public before the middle of the 19th century. For improving life-styles for the poor, Napoleon III strongly supported the development of green space systems in Paris by G.E. Haussmann. Napoleon III and Haussmann established and applied the urban green regulation within Paris urban planning. The purpose of this study is to investigate the green regulations Haussmann's Paris urban plan and urban green space system: and as a result of this, it can be an indicator for urban green space development in Korea.