• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.7C
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• pp.534-539
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• 2008

For an odd prime p, n=4k, and $d=((p^{2k}+1)/2)^2$, Seo, Kim, No, and Shin derived the correlation distribution of p-ary m-sequence of period $p^n-1$ and its decimated sequences by d. In this paper, two new families of p-ary sequences with family size $p^{2k}$ and maximum correlation magnitude $[2]sqrt{p^n}-1$ are constructed. The linear complexity of new p-ary sequences in the families are derived in the some cases and the upper and lower bounds of their linear complexity for general cases are presented.

• Biomolecules & Therapeutics
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• v.9 no.2
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• pp.79-87
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• 2001

Heat shock proteins serve as chaperone by preventing the aggregation of denatured proteins and promote survival of pathogens in harsh environments. In this study, heat shock gene encoding a 84-kDa (p84) protein, which is one of the three major heat shock proteins in S. pneumoniae, was cloned and characterized. PCR with a forward primer derived from N-terminal amino acid sequence of the p84 and a reverse primer derived from the conserved second ATP-binding region of Clp family was used for amplification of the gene encoding the p84 and subsequently the PCR product was used for sequence determination. Sequence analysis of the p84 gene demonstrated that it is a member of ClpL. The deduced amino acid sequence of pneumococcal ClpL shows homology with other members of the Clp family, and particularly, even in variable leader region, with bovine Clp-like protein and L. lactis ClpL. S. pneumoniae clpL is the smallest clop member (701 amono acids) containing the two conserved ATP-binding regions, and hydrophilic N-terminal variable region of pneu-mococcal Clp ATPase is much shorter than any known Clp ATPases. Histidine tagged ClpL was overexpressed and purified from E. coli. Immunoblot analysis employing antisera raised against pneumococcus p84 demonstrated no cross-reactivity with Clp analog in Eschericha coli, Staphylococcus aureus and human HeLa cells. Preimmunization of mice with ClpL extended mice life partially but did not protect them from death.

• Communications of the Korean Mathematical Society
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• v.9 no.4
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• pp.951-959
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• 1994

A sequence ${X_j : j \geq 1}$ of random variables is said to be pairwise positive quadrant dependent (pairwise PQD) if for any real $r-i,r_j$ and $i \neq j$ $$ P{X_i > r_i,X_j > r_j} \geq P{X_i > r_i}P{X_j > r_j} $$ (see [8]) and a sequence ${X_j : j \geq 1}$ of random variables is said to be associated if for any finite collection ${X_{i(1)},...,X_{j(n)}}$ and any real coordinatewise nondecreasing functions f,g on $R^n$ $$ Cov(f(X_{i(1)},...,X_{j(n)}),g(X_{j(1)},...,X_{j(n)})) \geq 0, $$ whenever the covariance is defined (see [6]). Instead of association Cox and Grimmett's [4] original central limit theorem requires only that positively linear combination of random variables are PQD (cf. Theorem $A^*$).

• Journal of applied mathematics & informatics
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• v.37 no.1_2
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• pp.37-52
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• 2019

In this paper we introduce a new concept for Riesz almost lacunary ${\chi}^3$ sequence spaces strong P - convergent to zero with respect to an Orlicz function and examine some properties of the resulting sequence spaces. We introduce and study statistical convergence of Riesz almost lacunary ${\chi}^3$ sequence spaces and some inclusion theorems are discussed.

• Genomics & Informatics
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• v.6 no.2
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• pp.72-76
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• 2008

Hypoxia-inducible factor $1{\alpha}\;(HIF1{\alpha})$ is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation (ODD) domain of $HIF1{\alpha}$ is responsible for the negative regulation of $HIF1{\alpha}$ in normoxia. The interactions of the $HIF1{\alpha}$ ODD domain with partner proteins such as von Hippel-Lindau tumor suppressor (pVHL) and p53 are mediated by two sequence motifs, the N- and C-terminal ODD(NODD and CODD). Multiple sequence alignment with $HIF1{\alpha}$ homologs from human, monkey, pig, rat, mouse, chicken, frog, and zebrafish has demonstrated that the NODD and CODD motifs have noticeably high conservation of the primary sequence across different species and isoforms. In this study, we carried out molecular dynamics simulation of the structure of the $HIF1{\alpha}$ CODD motif in complex with the p53 DNA-binding domain (DBD). The structure reveals specific functional roles of highly conserved residues in the CODD sequence motif of $HIF1{\alpha}$ for the recognition of p53.

• Bulletin of the Korean Mathematical Society
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• v.48 no.5
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• pp.1093-1103
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• 2011

We give the characterizations of the classes of matrix trans-formations ($m(\phi),{\ell}_p$), ($n(\phi),{\ell}_p$) ([5, Theorem 2]), (${\ell}_p,m(\phi)$) ([5, Theorem 1]) and (${\ell}_p,n(\phi)$) for $1{\leq}p{\leq}{\infty}$, establish estimates for the norms of the bounded linear operators defined by those matrix transformations and characterize the corresponding subclasses of compact matrix operators.

• Bulletin of the Korean Mathematical Society
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• v.17 no.1
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• pp.43-50
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• 1980

• Journal of the Korean Mathematical Society
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• v.39 no.6
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• pp.963-973
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• 2002

We study torsion phenomena in the integral cohomology of finite if-spaces X through the Eilenberg-Moore spectral sequence converging to H＊($\Omega$X; Z$_{p}$). We also investigate how the difference between the Z$_{p}$-filtration length f$_{p}$(X) and the Z$_{p}$-cup length c$_{p}$(X) on a simply connected finite H-space X is reflected in the Eilenberg-Moore spectral sequence converging to H＊($\Omega$X;Z$_{p}$). Finally we get the following result: Let p be an odd prime and X an n-connected finite H-space with dim QH＊ (X;Z$_{p}$) $\leq$ m. Then H＊(X;Z) is p-torsion free if (equation omitted).tion omitted).

• Journal of Microbiology and Biotechnology
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• v.24 no.3
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• pp.337-345
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• 2014

Pichia pastoris is one of the most widely used expression systems for the secretory expression of recombinant proteins. The secretory expression in P. pastoris usually makes use of the prepro $MAT{\alpha}$ sequence from Saccharomyces cerevisiae, which has a dibasic amino acid cleavage site at the end of the signal sequence. This is efficiently processed by Kex2 protease, resulting in the secretion of high levels of proteins to the medium. However, the proteins that are having the internal accessible dibasic amino acids such as KR and RR in the coding region cannot be expressed using this signal sequence, as the protein will be fragmented. We have identified a new signal sequence of 18 amino acids from a P. pastoris protein that can secrete proteins to the medium efficiently. The PMT1-gene-inactivated P. pastoris strain secretes a ~30 kDa protein into the extracellular medium. We have identified this protein by determining its N-terminal amino acid sequence. The protein secreted has four DDDK concatameric internal repeats. This protein was not secreted in the wild-type P. pastoris under normal culture conditions. We show that the 18-amino-acid signal peptide at the N-terminal of this protein is useful for secretion of heterologous proteins in Pichia.

• Honam Mathematical Journal
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• v.30 no.1
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• pp.9-20
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• 2008

Let ${X_i{\mid}i{\geq}1}$ be a strictly stationary sequence of associated random variables with mean zero and let ${\sigma}^2=EX_1^2+2\sum\limits_{j=2}^\infty{EX_1}{X_j}$ with 0 < ${\sigma}^2$ < ${\infty}$. Set $S_n={\sum\limits^n_{i=1}^\{X_i}$, the precise asymptotics for ${\varepsilon}^{{\frac{2(r-p)}{2-p}}-1}\sum\limits_{n{\geq}1}n^{{\frac{r}{p}}-{\frac{1}{p}}+{\frac{1}{2}}}P({\mid}S_n{\mid}{\geq}{\varepsilon}n^{{\frac{1}{p}}})$,${\varepsilon}^2\sum\limits_{n{\geq}3}{\frac{1}{nlogn}}p({\mid}Sn{\mid}{\geq}{\varepsilon\sqrt{nloglogn}})$ and ${\varepsilon}^{2{\delta}+2}\sum\limits_{n{\geq}1}{\frac{(loglogn)^{\delta}}{nlogn}}p({\mid}S_n{\mid}{\geq}{\varepsilon\sqrt{nloglogn}})$ as ${\varepsilon}{\searrow}0$ are established under the suitable conditions.