• PNF and Movement
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• 제13권1호
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• pp.17-23
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• 2015

Purpose: This study aims to identify changes in the mirror neuron system in normal people through mu rhythm during action observation of occupation-based intervention, purposeful activity and prepare a method of intervention form of occupation using occupation and activity. Methods: TThis study aims to identify changes in the mirror neuron system in normal people through mu rhythm during action observation of occupation-based intervention, purposeful activity and prepare a method of intervention form of occupation using occupation and activity. The activation of the mirror neuron system was compaired among 3 condition by oneway ANOVA. Results: The result of analysis showed mu suppression in all conditions. Although all conditions showed mu suppression, there was no significant difference among the conditions. Conclusion: The results suggest that the mirror neuron system is activated during action observation to be able to occupational therapy but the mirror neuron system is not separately activated among the conditions.

• 대한치과교정학회지
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• 제41권4호
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• pp.288-296
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• 2011

Objective: The purposes of this study were to evaluate the relationship between the dental and basal arch forms; to analyze their differences in the tapered, ovoid, and square arch forms in normal occlusion by using three-dimensional (3D) virtual models; and to test the hypothesis that the overjet and maxillomandibular basal arch width difference have a significantly positive correlation. Methods: Seventy-seven normal occlusion plaster casts were examined by 3D scanning. Facial axis (FA) and WALA points were digitized using the Rapidform 2006 software. The dimensions of the dental and basal arches and the overjet were measured. The samples were classified into 3 groups according to arch forms: tapered (n = 20), ovoid (n = 20), and square (n = 37). Analysis of variance (ANOVA) was used to compare the dental and basal arch dimensions. The Pearson correlation coefficients between the intercanine as well as the intermolar widths at the FA and WALA points were calculated. Results: With regard to the basal arch dimensions, the tapered arch form showed a larger mandibular intermolar depth than the ovoid. Strong correlations were noted between the basal and dental intermolar widths in both the upper and lower arches (r = 0.83 and 0.85, respectively). Moderate correlation was found between the upper and lower intercanine widths (r = 0.65 and 0.48, respectively). Conclusions: The 3 dental arch form groups differed only in some dimensions of the skeletal arch. Moderate correlations were found between the basal and dental intercanine widths. These findings suggest that the basal arch may not be a principle factor in determining the dental arch form.

• 대한치과교정학회지
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• 제31권3호
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• pp.347-355
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• 2001

상하악 전치부 치열은 치아의 형태 변위, 선천결손 등에 의해 종종 교합관계나 심미성에 문제점을 나타내게 된다. 이러한 문제점을 극복하기 위해 임상의는 전치부 비율을 진단시 이용하게 되나, 치열궁 형태, 견치간 폭경(intercanine width), 치열궁 장경(segment depth)과 치열궁 둘레(arch perimeter)에 따른 전치부 비율의 변화로 인해 이러한 비율을 전치부 교합관계 예측에 직접 적용하는데는 한계가 있다. 이에 본 연구에서는 한국성인 정상교합자 모델(남자:20쌍, 여자:20쌍)에서 상하악 전치부 치열궁 형태를 least square method로 조사하였다. 한국인 정상교합자의 상하악 전치부 치열궁 형태는 다항 함수(polynomial function), 베타 함수(beta function), 하이퍼볼릭 코사인 함수(hyperbolic cosine function) 순으로 곡선 접합(curve fitting)하였으며, 이러한 곡선 접합도는 남녀, 상하악에 관계없이 일정하였다. 또한 곡선접합(curve fitting)된 치열궁 형태를 바탕으로 견치간 폭경(intercanine width), 치열궁 장경(segment depth)과 치열궁 둘레(arch perimeter)간의 상관관계를 구하였다. 이러한 상관관계는 견치간 폭경에 따른 치열궁 형태 예측과 보다 정확한 전치부 비율에 대한 정보를 제공할 것이다.

• Journal of Chest Surgery
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• 제21권5호
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• pp.803-815
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• 1988

The present experiments were performed to confirm the hypothesis that xanthine oxidase[XOD], as a source and mechanism of oxygen radical production, plays an important role in the genesis of the reperfusion injury of ischemic myocardium. The experimental ischemic-reperfusion injury was induced in isolated, Langendorff preparations of rat hearts by 60 min. Of global ischemia with aortic clamping followed by 20 min. of reperfusion with oxygenated Krebs-Henseleit solution[pH 7.4, 37*C]. The results were as follows: 1. The releases of creatine phosphokinase and a lipid peroxidation product, malondialdehyde[MDA] into the coronary effluent were abruptly increased upon reperfusion of ischemic hearts. The increases of the enzyme and MDA were suppressed significantly in the hearts removed from rats pretreated with allopurinol, a specific XOD inhibitor[20mg/kg, oral, 24 hrs and 2 hrs before study]. This effect of allopurinol was comparable to that of oxygen radical scavengers, superoxide dismutase[5, 000U] and catalase[12, 500 U]. 2. The increased SOD-inhibitable reduction of ferricytochrome C, which was infused to the hearts starting with reperfusion, was significantly suppressed in allopurinol pretreated hearts. 3. Activities of myocardial XOD were compared in the normal control hearts and the ischemic ones. Total enzyme activities were not different in both hearts. However, comparing with the control, the ischemic ones showed higher activity in 0-form and lower activities in D-form and D/O-form. 4. In the ischemic hearts, phenylmethylsulfonyl fluoride, a serine protease inhibitor, prevented significantly the increase of 0-form and the decreases of D and D/O-form, while thiol reagents did not affect the changes of the enzyme. 5. The increase of 0-form and the decreases of D and D/0-form were not significant in both calcium-free perfused and pimozide, a calmodulin inhibitor, treated ischemic hearts. 6. The SOD-inhibitable reduction of ferricytochrome C were suppressed by PMSF and pimozide treatment as well as by calcium-free perfusion. It is suggested from these results that in the ischemic rat myocardium, xanthine oxidase is converted to oxygen radical producing 0-form by calcium, calmodulin-dependent proteolysis and plays a contributing role in the genesis of ischemic-reperfusion injury by producing oxygen free radicals.

• 한국산학기술학회논문지
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• 제14권1호
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• pp.411-417
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• 2013

철도선로에 설치되는 전철주기초의 모멘트에 대한 거동을 파악하기 위한 실물 재하시험을 수행하였다. 현장타설방식으로 설치된 폭 1.1m, 깊이 2.2m의 정사각형 전철주기초 2본에 대하여 실제 조건과 동일한 모멘트 위주의 하중을 가하여 기초의 항복모멘트를 확인하였다. 거푸집 설치 여부가 기초의 저항모멘트에 미치는 영향을 평가하기 위하여 동일한 조건에서 거푸집을 설치한 경우와 그렇지 않은 경우에 대하여 시험하였다. 거푸집 설치 효과로 흙과 지반의 접촉면이 매끈해지면서 발생하는 마찰력 감소보다는, 거푸집 미설치 시 굴착지반의 이완에 의한 기초 주변지반의 강도 감소 효과가 더 크게 나타나는 것으로 나타났다. 비례계수를 사용하여 포괄적으로 전철주기초의 저항모멘트를 산정하는 현행 설계방법으로는 거푸집의 설치효과를 적절히 고려할 수 없었으며, 연직응력과 마찰력을 분리하여 저항모멘트를 산정하는 경우에는 기초와 지반의 마찰각을 20% 감소시킴으로써 거푸집 설치효과에 대한 합리적인 고려가 가능하였다.

• 생물정신의학
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• 제2권1호
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• pp.57-62
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• 1995

항정신병 약물인 clozapine이 주로 작용하는 도파민 수용체로 알려진 도파민 $D_4$ 수용체는 각각 50 염기쌍에 해당하는 크기의 차이가 있음이 알려져 PCR을 이용해 정신분열증 환자와 정상대조군을 대상으로 도파민 $D_4$ 수용체 유전자의 대립형질 분포를 알아보았다. 정신분열증 환자군과 대조군 모두에 있어 여섯종류의 대립형질의 관찰되었으며 정신분열증 환자에서 네번 반복형태의 대립형질이 수적으로 더 많이 관찰되었지만 통계적으로 유의한 차이는 없었으며 정신분열증과 관련된 도파민 $D_4$ 수용체 유전자의 대립형질은 확인되지 않았다. 그러나 보다 객관적인 정보를 얻기 위해서 clozapine에 대한 반응에 따라 정신분열증 환자의 아형을 분류하고 그 아형에 따른 도파민 $D_4$ 수용체 유전자 대립형질분포의 차이에 관한검증이 필요하며, 나아가 도파민 $D_4$ 수용체 유전자의 발현에 있어 정신분열증 환자와 정상인에 차이가 있는지 여부를 밝히는 추적연구가 필요할 것으로 사료된다.

• 대한치과교정학회지
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• 제22권3호
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• pp.675-690
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• 1992

The purpose of this study was to obtain the lingual morphology (size, angulation, contour, eminence) of adults with normal occlusion in order to provide the basic data for lingual bracket and lingual arch form in Korean. The subjects (Male: 50, Female: 50) were selected who have normal occlusion and dental casts were prepared. Tooth size, angulation, arch width, horizontal contour, lingual eminence were measured for all 28 teeth both upper and lower arch. The results were as follows: 1. Measuring items of all individual teeth for adults with normal occlusion were obtained. 2. In comparison tests, there was a statistically difference between intermolar widths $(\underline{6}\;to\;\underline{6})$ before occlusal reduction and intermolar width $(\underline{6}\;to\;\underline{6},\underline{7}\;to\;\underline{7})$ after occlusal reduction only all the other measuring items showed no statistically differences. 3. There was small variation in horizontal contour of lingual surface on lower incisors and upper and lower bicuspids. The other teeth showed somewhat greater variations. 4. There was offset between canine and bicuspid in upper arch while there was no prominent offset in lower arch.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.681-685
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• 2004

A media-feeding (or media-transport) system is a key component in daily consumer systems such as printers, copiers and ATM's. The role of the media-transport system is to feed a medium, which is usually in the form of a thin film, to the main process in a uniform and repeatable manner. Even small slippage between the media and the feeding rollers could significantly degrade the performance of the entire system. The slippage between the medium and the feeding rollers is determined by many parameters which include the friction coefficient between the feeding rollers and the medium material, the angular velocity of the feeding rollers, and the normal force applied by feeding rollers on the medium. This paper investigates the effect of the normal force and the angular velocity of feeding rollers on the slippage of the medium. Authors have constructed a test bed for experiments, which consists of a feeding module and various measuring devices. Using regular paper as media being fed, the authors experimentally measured the slippage of the medium under various normal forces and angular velocities of driving feeding roller. Also the authors developed a novel two-dimensional simulation model for the media-transport system. The paper medium is modeled as a set of multiple rigid bodies interconnected by revolute joints and rotational springs and dampers. Simulations were executed using a multi-body dynamic analysis tool called RecurDy $n^{ⓡ}$. The slippage obtained by the simulation is compared to experimental results.ults.

• Bulletin of the Korean Chemical Society
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• 제32권8호
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• pp.2732-2736
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• 2011

In pH 4.2 HAc-NaAc buffer solution, horseradish peroxidase (HRP) catalyzed $H_2O_2$ oxidation of nanosilver to form $Ag^+$. After centrifugation, $Ag^+$ in the supernatant can be measured by graphite furnace atomic absorption spectrophotometry (GFAAS) at the silver absorption wavelength of 328.1 nm. When HRP concentration increased, the $Ag^+$ concentration in the supernatant increased, and the absorption value enhanced. The HRP concentration in the range of 0.84-50 $ng{\cdot}mL^{-1}$ was linear to the enhanced absorption value (${\Delta}A$), with a regression equation of ${\Delta}A$=0.012C+0.11, correlation coefficient of 0.9988, and detection limit of 0.41 $ng{\cdot}mL^{-1}$ HRP. The proposed GFAAS method was used to detect HRP in waste water samples, with satisfactory results.

• 대한수의학회지
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• 제39권5호
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• pp.974-985
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• 1999

Osteoporosis is defined as a decrease in bone mass that leads to an increased risk of fracture. The therapeutic effect of $1{\alpha}$,25 dihydroxycholecalciferol, the hormonal form of vitamin $D_3$ that mediates calcium translation in intestine and bone, on the healing process of fracture has still been controversial. These studies were designed to understand the healing process of normal fibular fracture, the osteoporotic changes after ovariectomy, and the therapeutic effects of $1{\alpha}$,25 dihydroxycholecalciferol on the osteoporotic fracture in rats. The simple transverse fractures of rat fibulae were produced with a rotating diamond saw. The changes of the biochemical and mechanical indices of rats were investigated. The mechanical study based on bending test revealed the healing of the fibular fracture in the 5th week after simple transverse fracture. The osteoporosis impaired more the healing of osteoporotic fibular fracture than normal non-osteoporotic fibular fracture. The healing process of osteoporotic fracture was facilitated by the treatment with $1{\alpha}$,25 dihydroxycholecalciferol, however, was delayed more than the healing process of normal fracture. The bone strength based on the bending test also confirmed this tendency. The bone strengths in the 5th week after fracture of normal bone, osteoporotic bone, and $1{\alpha}$,25 dihydroxycholecalciferol-treated osteoporotic bone were 75%, 41%, and 67%, respectively, in comparison with those of intact bone. In conclusion, $1{\alpha}$,25 dihydroxycholecalciferol was effective in promoting the osteoporotic fracture healing.