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Differences of EEG Activation in Mirror Neuron System during Action Observation for Occupation-based, Purposeful Activity, Preparatory Method in adult subjects (일반 성인의 작업과 활동의 중재 형태에 대한 행위 관찰 시 거울신경세포 시스템의 EEG 활성도 차이)

  • Ko, Hyo-Eun;Yun, Tae-Won;Chung, Hyun-Ae
    • PNF and Movement
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    • v.13 no.1
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    • pp.17-23
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    • 2015
  • Purpose: This study aims to identify changes in the mirror neuron system in normal people through mu rhythm during action observation of occupation-based intervention, purposeful activity and prepare a method of intervention form of occupation using occupation and activity. Methods: TThis study aims to identify changes in the mirror neuron system in normal people through mu rhythm during action observation of occupation-based intervention, purposeful activity and prepare a method of intervention form of occupation using occupation and activity. The activation of the mirror neuron system was compaired among 3 condition by oneway ANOVA. Results: The result of analysis showed mu suppression in all conditions. Although all conditions showed mu suppression, there was no significant difference among the conditions. Conclusion: The results suggest that the mirror neuron system is activated during action observation to be able to occupational therapy but the mirror neuron system is not separately activated among the conditions.

Three-dimensional evaluation of the relationship between dental and basal arch forms in normal occlusion (정상교합자에서 치열궁과 기저궁 관계의 삼차원적 평가)

  • Kim, Kwang-Yoo;Bayome, Mohamed;Kim, Kon-Tae;Han, Seong-Ho;Kim, Yoon-Ji;Baek, Seung-Hak;Kook, Yoon-Ah
    • The korean journal of orthodontics
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    • v.41 no.4
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    • pp.288-296
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    • 2011
  • Objective: The purposes of this study were to evaluate the relationship between the dental and basal arch forms; to analyze their differences in the tapered, ovoid, and square arch forms in normal occlusion by using three-dimensional (3D) virtual models; and to test the hypothesis that the overjet and maxillomandibular basal arch width difference have a significantly positive correlation. Methods: Seventy-seven normal occlusion plaster casts were examined by 3D scanning. Facial axis (FA) and WALA points were digitized using the Rapidform 2006 software. The dimensions of the dental and basal arches and the overjet were measured. The samples were classified into 3 groups according to arch forms: tapered (n = 20), ovoid (n = 20), and square (n = 37). Analysis of variance (ANOVA) was used to compare the dental and basal arch dimensions. The Pearson correlation coefficients between the intercanine as well as the intermolar widths at the FA and WALA points were calculated. Results: With regard to the basal arch dimensions, the tapered arch form showed a larger mandibular intermolar depth than the ovoid. Strong correlations were noted between the basal and dental intermolar widths in both the upper and lower arches (r = 0.83 and 0.85, respectively). Moderate correlation was found between the upper and lower intercanine widths (r = 0.65 and 0.48, respectively). Conclusions: The 3 dental arch form groups differed only in some dimensions of the skeletal arch. Moderate correlations were found between the basal and dental intercanine widths. These findings suggest that the basal arch may not be a principle factor in determining the dental arch form.

The new approach to maxillary and mandibular anterior dental arch forms - In Korean normal occlusion models (상하악 전치부 치열궁 형태에 대한 새로운 접근 - 한국성인 정상교합자 모델에서)

  • Ha, Man-Hee;Son, Woo-Sung;Yang, Hoon-Chul
    • The korean journal of orthodontics
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    • v.31 no.3 s.86
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    • pp.347-355
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    • 2001
  • Maxillary and mandibular anterior dental arches often have the problems of occlusal relation and esthetics by malformations of teeth, congenital missing, et at. Though the clinician usually use the anterior ratio to overcome this problems, he has the limitation of a direct application this ratio to the prediction of anterior occlusal relationship by the change of anterior ratio as dental arch form, intercanine width, segment depth and arch perimeter. So this study examine maxillary and mandibular anterior dental arch forms by least square method using Korean normal occlusion models(man : 20 casts, woman : 20 casts). Maxillary and mandibular anterior dental arches of Korean normal occlusion models are curve fitted to polynomial function, beta function, hyperbolic cosine function in order. And this accuracy of curve fitting is constant regardless of man/woman and maxilla/mandible. The relationships between intercanine width, segment depth, and arch perimeter based on this owe fitted dental arch form are acquired. This relationships will give the prediction of anterior dental arch form and the information of more accurate anterior ratio according to intercanine width.

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Conversion of Myocardial Xanthine Oxidase in Ischemic Heart of Rat (허혈심근 Xanthine Oxidase 의 전환에 관한 연구)

  • 박창권
    • Journal of Chest Surgery
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    • v.21 no.5
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    • pp.803-815
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    • 1988
  • The present experiments were performed to confirm the hypothesis that xanthine oxidase[XOD], as a source and mechanism of oxygen radical production, plays an important role in the genesis of the reperfusion injury of ischemic myocardium. The experimental ischemic-reperfusion injury was induced in isolated, Langendorff preparations of rat hearts by 60 min. Of global ischemia with aortic clamping followed by 20 min. of reperfusion with oxygenated Krebs-Henseleit solution[pH 7.4, 37*C]. The results were as follows: 1. The releases of creatine phosphokinase and a lipid peroxidation product, malondialdehyde[MDA] into the coronary effluent were abruptly increased upon reperfusion of ischemic hearts. The increases of the enzyme and MDA were suppressed significantly in the hearts removed from rats pretreated with allopurinol, a specific XOD inhibitor[20mg/kg, oral, 24 hrs and 2 hrs before study]. This effect of allopurinol was comparable to that of oxygen radical scavengers, superoxide dismutase[5, 000U] and catalase[12, 500 U]. 2. The increased SOD-inhibitable reduction of ferricytochrome C, which was infused to the hearts starting with reperfusion, was significantly suppressed in allopurinol pretreated hearts. 3. Activities of myocardial XOD were compared in the normal control hearts and the ischemic ones. Total enzyme activities were not different in both hearts. However, comparing with the control, the ischemic ones showed higher activity in 0-form and lower activities in D-form and D/O-form. 4. In the ischemic hearts, phenylmethylsulfonyl fluoride, a serine protease inhibitor, prevented significantly the increase of 0-form and the decreases of D and D/O-form, while thiol reagents did not affect the changes of the enzyme. 5. The increase of 0-form and the decreases of D and D/0-form were not significant in both calcium-free perfused and pimozide, a calmodulin inhibitor, treated ischemic hearts. 6. The SOD-inhibitable reduction of ferricytochrome C were suppressed by PMSF and pimozide treatment as well as by calcium-free perfusion. It is suggested from these results that in the ischemic rat myocardium, xanthine oxidase is converted to oxygen radical producing 0-form by calcium, calmodulin-dependent proteolysis and plays a contributing role in the genesis of ischemic-reperfusion injury by producing oxygen free radicals.

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Moment Resisting Behaviors of Railway Electric Pole Foundation According to Form Work Methods (거푸집 설치 방법에 따른 철도 전철주기초의 모멘트 저항 거동)

  • Lee, Su-Hyung;Lee, Seung-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.1
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    • pp.411-417
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    • 2013
  • The moment responses of electric pole foundations for a railroad were investigated using real-scale load tests. Large overturning moments were applied to two square rigid piles with a 1.1 m width and a 2.2 m embedded depth. Two different installation methods-with and without a form-were applied to evaluate the influence of the form work on the moment capacities of the foundations. The reduction of ground strength caused by the excavation without a form is more pronounce than the decrease of frictional strength due to the smooth concrete surface with a form. From the test results, it is found that the current design method which applies a proportional coefficient to consider the effect of a form work is not appropriate. When the normal and frictional stressed is considered separately, the effect of a form work can be estimated reasonably by reducing the friction angle between soil and foundation by 20%.

Association between Dopamine $D_4$ Receptor Gene Variants and Schizophrenia (도파민 $D_4$ 수용체 유전자 Variants와 정신분열증과의 연관성)

  • Lee, Hong Shick;Shin, Dong Won
    • Korean Journal of Biological Psychiatry
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    • v.2 no.1
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    • pp.57-62
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    • 1995
  • Objects : Clozapine, prototype of the atypical neuroleptics, was known to have unique antipsychotic effect with a few extrapyramidal effects. While most typical antipsychotic agents mainly block $D_2$ receptors, clozapine has higher affinity for dopamine $D_4$ receptor than for $D_2$ receptor. Many researchers have tried to find out the relationship between schizophrenia and the abnormality of the genes coding dopamine receptors. But no consistent findings were reported. Recently, dopamine $D_4$ receptor was fully sequenced, and the alleles of dopamine $D_4$ receptor gene was found in unusual form on the 48th base pair. Our study was performed to identify the distribution of the dopamine $D_4$ receptor alleles of schizophrenics and normal controls, and whether any difference between the dopamine $D_4$ receptor alleles of schizophrenics and that of normal controls exists. Methods : DNA was extracted from the blood of schizophrenic patients(N=60) and normal controls(N=60). Part of the dopamine $D_4$ receptor gene was amplified by PCR, and amplified DNA was electrophoresed. Authors compared the distribution of the alleles of dopamine $D_4$ receptor gene of normal controls and that of schizophrenic patients. Results : Six kinds of alleles of $D_4$ receptor were observed both groups. The fourth repeat form of alleles was the most common in both schizophrenic patients(75.8%) and normal controls(70.3%), so there was not significant difference between two groups. Conclusion : The Difference in the distribution of the dopamine $D_4$ receptor gene alleles is not thought to be responsible for the pathophysiology of the schizophrenia. However, the difference in the expression of the dopamine $D_4$ receptor gene between normal and schizophrenia is left to be scrutinized.

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A MORPHOLOGIC CHARACTERISTICS STUDY OF CROWN OF LINGUAL SURFACE WITH NORMAL OCCLUSION IN KOREAN ADULTS (한국인 성인 정상교합자 치관의 설측면 특징에 관한 연구)

  • Yu, Hyung-Seog;Park, Young-Chel
    • The korean journal of orthodontics
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    • v.22 no.3 s.38
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    • pp.675-690
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    • 1992
  • The purpose of this study was to obtain the lingual morphology (size, angulation, contour, eminence) of adults with normal occlusion in order to provide the basic data for lingual bracket and lingual arch form in Korean. The subjects (Male: 50, Female: 50) were selected who have normal occlusion and dental casts were prepared. Tooth size, angulation, arch width, horizontal contour, lingual eminence were measured for all 28 teeth both upper and lower arch. The results were as follows: 1. Measuring items of all individual teeth for adults with normal occlusion were obtained. 2. In comparison tests, there was a statistically difference between intermolar widths $(\underline{6}\;to\;\underline{6})$ before occlusal reduction and intermolar width $(\underline{6}\;to\;\underline{6},\underline{7}\;to\;\underline{7})$ after occlusal reduction only all the other measuring items showed no statistically differences. 3. There was small variation in horizontal contour of lingual surface on lower incisors and upper and lower bicuspids. The other teeth showed somewhat greater variations. 4. There was offset between canine and bicuspid in upper arch while there was no prominent offset in lower arch.

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A Study on Slipping Phenomenon in a Media Transport System (급지 장치에서의 미끄러짐 현상에 대한 연구)

  • 유재관;이순걸;임성수;김시은
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2004.10a
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    • pp.681-685
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    • 2004
  • A media-feeding (or media-transport) system is a key component in daily consumer systems such as printers, copiers and ATM's. The role of the media-transport system is to feed a medium, which is usually in the form of a thin film, to the main process in a uniform and repeatable manner. Even small slippage between the media and the feeding rollers could significantly degrade the performance of the entire system. The slippage between the medium and the feeding rollers is determined by many parameters which include the friction coefficient between the feeding rollers and the medium material, the angular velocity of the feeding rollers, and the normal force applied by feeding rollers on the medium. This paper investigates the effect of the normal force and the angular velocity of feeding rollers on the slippage of the medium. Authors have constructed a test bed for experiments, which consists of a feeding module and various measuring devices. Using regular paper as media being fed, the authors experimentally measured the slippage of the medium under various normal forces and angular velocities of driving feeding roller. Also the authors developed a novel two-dimensional simulation model for the media-transport system. The paper medium is modeled as a set of multiple rigid bodies interconnected by revolute joints and rotational springs and dampers. Simulations were executed using a multi-body dynamic analysis tool called RecurDy $n^{ⓡ}$. The slippage obtained by the simulation is compared to experimental results.ults.

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Graphite Furnace Atomic Absorption Spectrophotometric Determination of Trace Horseradish Peroxidase Using Nanosilver

  • Jiang, Zhi-Liang;Tang, Ya-Fang;Wei, Lin;Liang, Ai-Hui
    • Bulletin of the Korean Chemical Society
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    • v.32 no.8
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    • pp.2732-2736
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    • 2011
  • In pH 4.2 HAc-NaAc buffer solution, horseradish peroxidase (HRP) catalyzed $H_2O_2$ oxidation of nanosilver to form $Ag^+$. After centrifugation, $Ag^+$ in the supernatant can be measured by graphite furnace atomic absorption spectrophotometry (GFAAS) at the silver absorption wavelength of 328.1 nm. When HRP concentration increased, the $Ag^+$ concentration in the supernatant increased, and the absorption value enhanced. The HRP concentration in the range of 0.84-50 $ng{\cdot}mL^{-1}$ was linear to the enhanced absorption value (${\Delta}A$), with a regression equation of ${\Delta}A$=0.012C+0.11, correlation coefficient of 0.9988, and detection limit of 0.41 $ng{\cdot}mL^{-1}$ HRP. The proposed GFAAS method was used to detect HRP in waste water samples, with satisfactory results.

Therapeutic effects of 1α,25 dihydroxycholecalciferol on osteoporotic fracture in a rat model (랫드에서 1α,25 dihydroxycholecalciferol의 골다공증성 골절 치유효과)

  • Bae, Chun-sik
    • Korean Journal of Veterinary Research
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    • v.39 no.5
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    • pp.974-985
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    • 1999
  • Osteoporosis is defined as a decrease in bone mass that leads to an increased risk of fracture. The therapeutic effect of $1{\alpha}$,25 dihydroxycholecalciferol, the hormonal form of vitamin $D_3$ that mediates calcium translation in intestine and bone, on the healing process of fracture has still been controversial. These studies were designed to understand the healing process of normal fibular fracture, the osteoporotic changes after ovariectomy, and the therapeutic effects of $1{\alpha}$,25 dihydroxycholecalciferol on the osteoporotic fracture in rats. The simple transverse fractures of rat fibulae were produced with a rotating diamond saw. The changes of the biochemical and mechanical indices of rats were investigated. The mechanical study based on bending test revealed the healing of the fibular fracture in the 5th week after simple transverse fracture. The osteoporosis impaired more the healing of osteoporotic fibular fracture than normal non-osteoporotic fibular fracture. The healing process of osteoporotic fracture was facilitated by the treatment with $1{\alpha}$,25 dihydroxycholecalciferol, however, was delayed more than the healing process of normal fracture. The bone strength based on the bending test also confirmed this tendency. The bone strengths in the 5th week after fracture of normal bone, osteoporotic bone, and $1{\alpha}$,25 dihydroxycholecalciferol-treated osteoporotic bone were 75%, 41%, and 67%, respectively, in comparison with those of intact bone. In conclusion, $1{\alpha}$,25 dihydroxycholecalciferol was effective in promoting the osteoporotic fracture healing.

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