• BMB Reports
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• 제38권2호
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• pp.177-181
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• 2005

Effects of common electrophoretic reagents, reducing agents ($\beta$-mercaptoethanol [BME] and DTT), denaturants (SDS and urea), and non-ionic detergent (Triton X-100), on the activity and stability of bovine plasmin (b-pln) and human plasmin (h-pln) were compared. In the presence of 0.1% SDS (w/v), all reagents completely inhibited two plns, whereas SDS (1%) and urea (1 M) denatured plns recovered their activities after removal of SDS by treatment of 2.5% Triton X-100 (v/v). However, reducing agents (0.1 M of BME and DTT) treated plns did not restore their activities. Based on a fibrin zymogram gel, five (from b-pln) and four (from h-pln) active fragments were resolved. Two plns exhibited unusual stability in concentrated SDS and Triton X-100 (final 10%) and urea (final 6 M) solutions. Two bands, heavy chain-2 (HC-2) and cleaved heavy chain-2 (CHC-2), of b-pln were completely inhibited in 0.5% SDS or 3 M urea, whereas no significant difference was found in h-pln. Interestingly, 50 kDa (cleaved heavy chain-1, CHC-1) of b-pln and two fragments, 26 kDa (light chain, LC) and 29 kDa (microplasmin, MP), of h-pln were increased by SDS in a concentration dependent manner. We also found that the inhibition of SDS against both plns was reversible.

• 천문학논총
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• 제32권1호
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• pp.313-315
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• 2017

We present physical properties of $24{\mu}m$ galaxies detected by AKARI and Spitzer and their evolution between redshifts 0.4 < z < 2. Using multi-wavelength data from X-ray to radio observations in NEP Deep Field (for AKARI) and Subaru/XMM-Newton Deep Field (for Spitzer), we derive photometric redshift, stellar mass, star-formation rate (SFR), dust extinction magnitude and rest-frame luminosities/colors of the $24{\mu}m$ galaxies from photometric SED fitting. We infer the SFRs from rest-frame ultraviolet luminosity and total infrared luminosity calibrated against Herschel photometric data. For both survey fields, we obtain complete samples with stellar mass of > $10^{10}M_{\odot}$ and SFR of > $30M_{\odot}/yr$ up to z = 2. We find that specific SFRs evolves with redshift at all stellar masses in NON-power-law galaxies (non-PLGs) as star-formation dominant luminous infrared galaxies (LIRGs). The correlations between specific SFR and stellar mass in the Spitzer and AKARI galaxy samples are well consistent with trends of the main sequence galaxies. We also discuss nature of PLGs and their evolution.

• 한국전기전자재료학회논문지
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• 제30권8호
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• pp.484-490
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• 2017

We investigated the rewritable operation of a non-volatile memory device composed of Al (top)/$TiO_2$/indium-zinc-oxide (IZO)/Al (bottom). The oxygen-deficient IZO layer of the device was spin-coated with 0.1 M indium nitrate hydrate and 0.1 M zinc acetate dehydrate as precursor solutions, and the $TiO_2$ layer was fabricated by atomic layer deposition. The oxygen vacancies IZO layer of an active component annealed at $400^{\circ}C$ using thermal annealing and it was proven to be in oxygen vacancies and oxygen binding environments with OH species and heavy metal ions investigated by X-ray photoelectron spectroscopy. The device, which operates at low voltages (less than 3.5 V), exhibits non-volatile memory behavior consistent with resistive-switching properties and an ON/OFF ratio of approximately $3.6{\times}10^3$ at 2.5 V.

• 천문학회지
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• 제28권1호
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• pp.77-87
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• 1995

An attempt has been made to analyze time series of $H_\alpha,\;H_\beta,\;and\; H_\gamma$ line profiles taken from a 3B/X6.1 flare which occurred on Oct. 27, 1991 in an active region, NOAA 6891. A total of 22 sets of $H_\alpha,\;H_\beta,\;and\; H_\gamma$ taken with a low and non-uniform time resolution of 10-40 seconds were scanned by PDS with absolute intensity calibration to derive the physical characteristics of the material in the flare chromosphere. Our . results are as follows: (1) The lower Balmer lines observed during the flare activity are broadened by Stark effect. (2) At the peak of the flare activity, the electron temperature of the Balmer line emitting region reaches up to 35000K and its geometrical thickness increases to a scale of $10^4km$, suggesting that high energy particles penetrate deep into the photospheric level.

• 천문학회보
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• 제41권2호
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• pp.29.5-30
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• 2016

(1) The correlation between the mass of supermassive black holes (SMBHs) and the properties of their host galaxies suggests that SMBHs and host galaxies are closely linked in their formation and evolution. While the exact origin of their relationship is still under debate, theoretical models often invoke feedback from active galactic nuclei as a crucial mechanism for establishing the BH-host correlation. In the first part of my talk, I will present our efforts to find observational sign of the AGN feedback in young luminous AGNs. (2) While intermediate-mass black hole (IMBH) is thought be cosmologically important class to understand the link between stellar mass black holes and SMBHs, it is extremely rare in the present-day Universe. In the second part of this talk, I will report a Gemini/GMOS-N IFU study of an ultraluminous X-ray source in NGC 5252, which is a possible candidate of an off-nuclear non-stellar black hole.

• 천문학회보
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• 제42권1호
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• pp.27.4-27.4
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• 2017

(1) The correlation between the mass of supermassive black holes (SMBHs) and the properties of their host galaxies suggests that SMBHs and host galaxies are closely linked in their formation and evolution. While the exact origin of their relationship is still under debate, theoretical models often invoke feedback from active galactic nuclei as a crucial mechanism for establishing the BH-host correlation. In the first part of my talk, I will present possible observational biases in the BH-host relation, and methods to overcome these biases. I will also report our efforts to find observational sign of the AGN feedback in high-z young luminous AGNs. (2) While intermediate-mass black hole (IMBH) is thought be cosmologically important class to understand the link between stellar mass black holes and SMBHs, it is extremely rare in the present-day Universe. In the second part of this talk, I will report a Gemini/GMOS-N IFU study of an ultraluminous X-ray source in NGC 5252, which is a possible candidate of an off-nuclear non-stellar black hole.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2015년도 추계학술발표대회
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• pp.1800-1803
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• 2015

기존의 센서가 컴퓨팅과 통신기능을 갖추게 되면서, 분산된 센서가 통신망을 통해 전달하는 현장의 물리량 변화를 직관적으로 판단할 수 있게 돕는 재사용 가능한 데이터 시각화 컴포넌트의 수요가 높다. 본 연구에서는 라즈베리파이를 IoT센서로 보고, 분산된 복수의 IoT센서들로부터 현장의 온도 값을 웹 서버에서 모아, 사용자가 클라이언트 단말을 통해 현장의 온도변화 상황을 직관성 있게 판단할 수 있도록 돕는 회귀분석 시각화컴포넌트를 개발하였다. 본 연구에서는 이종분산의 IoT 환경에서 다양한 브라우저를 지원할 수 있도록 Non-ActiveX 기반 데이터 시각화 컴포넌트 개발을 논한다. 본 연구의 결과는 단일의 온도센서가 보고하는 온도값을 현장의 온도값이라고 대표할 수 없는 항온항습 시설의 온도 감시제어 응용에서 본 연구 결과가 널리 활용될 것으로 본다.

• Tuberculosis and Respiratory Diseases
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• 제45권4호
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• pp.705-713
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• 1998

연구배경: 당뇨병 환자의 폐결핵은 비당뇨병 환자에 비해 중증의 비율이 높다는 보고가 있었으나 입원한 당뇨병환자와 결핵실태조사에 의한 일반인을 비교하였으므로 입원한 당뇨병환자가 상대적으로 더 심한 폐결핵을 가지고 있을 수 있다. 이에 저자들은 입원한 환자를 대상으로 당뇨병군과 비당뇨병군 환자사이에 폐결핵 임상양상의 차이를 비교하고, 폐결핵 진단시 당뇨병의 정도와 폐결핵의 중증도와의 관계를 조사하고 혈당의 조절정도가 폐결핵의 치료결과에 어떠한 영향을 주는가를 알아보고자 본 연구를 시행하였다. 방 법: 1995년 1월 1일부터 1996년 12월 31일까지 경희의료원에 입원한 폐결핵환자중 당뇨병에 동반된 폐결핵 환자 82명과 비당뇨병성 폐결핵환자 83명을 대상으로 폐결핵 임상양상, 진단 방법, 방사선 소견, 치료반응의 차이를 비교하고, 당뇨병환자의 폐결핵에 있어서는 폐결핵 진단시 Hb Alc와 폐결핵의 중증도와의 관계, 폐결핵 치료종결시 혈당조절정도와 폐결핵 치료 결과를 조사하였다. 결 과: 당뇨병군과 비당뇨병군에서 폐결핵 환자의 성비는 각각 58 : 24, 62: 21로써 두군 모두 남자가 많았다. 평균연령은 당뇨병군이 55세, 비당뇨병군이 44세로 연령 분포를 보면 당뇨병군은 50-60 대에 많고 비당뇨병군은 20-30 대에 많았다. 폐결핵 발병빈도는 당뇨병의 이환기간이 5-10년일 때 가장 높았다. 흉부 방사선 소견상 병변의 범위는 당뇨병군과 비당뇨병군에서 의미 있는 차이는 없었고, 두군 모두에서 중등증인 경우가 각각 60.9, 50.6%로 가장 많았다. 폐하야 결핵은 당뇨병군(19.5%)에서 비당뇨병군(4.8%)에 비해 높았다(p<0.05). 이환된 폐엽의 수는 당뇨병군(2.35엽)과 비당뇨병군(2.21엽) 모두 다수 엽의 침범소견을 보였다. 두군의 평균 치료기간은 당뇨병군에서 10개월, 비당뇨병군에서 8개월이었으며 치료반응에 있어서 완치는 당뇨병군 85.4%, 비당뇨병군 89.2%, 치료실폐가 각각 8.6, 3.6%, 재발은 각각 3.6, 1.2%, 폐결핵으로 사망한 경우는 각각 1명씩으로 두 군간의 통계학적으로 의미 있는 차이는 없었다. 폐결핵 진단당시 HbAlc와 방사선학적 소견상 폐결핵의 중증도 사이에는 의미 있는 관련성이 없었다. 폐결핵 치료기간동안 혈당조절이 잘된 경우 완치율이 높았고(p<0.05), 혈당조절이 불량한 경우 치료실패율이 높았다 (p<0.05). 결 론: 입원치료를 받았던 당뇨병군과 비당뇨병군의 폐결핵 환자들의 임상상과 폐결핵의 중증도, 치료결과에는 차이가 없었으나 당뇨병군에서 혈당조절이 불량한 환자에서 치료실패율이 높아 당뇨병이 있는 폐결핵 환자에서는 혈당의 적절한 조절이 필수적이며, 고혈당 환자에서 결핵치료 실패를 초래하는 기전에 대한 연구가 필요하겠다.

• 한국표면공학회지
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• 제51권3호
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• pp.164-171
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• 2018

In this study, we have fabricated pure titanium (Ti)/hydroxyapatite (HA) double layer coating on medical grade PEEK from magnetron sputtering system, an investigation was performed whether the surface can be had more improve bio-active for orthopedi/dental applications than that of non-coated one. Pure Ti and HA coating layer were obtained by a radio-frequency and direct current power magnetron sputtering system. The microstructures surface, mechanical properties and wettability of the pure Ti/HA double layer deposited on the PEEK were analyzed by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), nano-indentation, and contact angle test. According to the EDS and XRD results, the composition and crystal structure of pure Ti and HA coated surface were verified. The elastic modulus and hardness value were increased by pure Ti and HA coating, and the pure Ti/HA double layer coating surface has the highest value. The contact angle showed higher value for pure Ti/HA double layered coating specimens than that of non-coated (PEEK) surface.

• Journal of Electrochemical Science and Technology
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• 제12권1호
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• pp.137-145
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• 2021

Among the non-precious metal catalysts, iron-nitrogen doped carbon (Fe-N/C) catalysts have been recognized as the most promising candidates for an alternative to Pt-based catalysts for the oxygen reduction reaction (ORR) under alkaline and acidic conditions. In this study, the nano replication method using mesoporous silica, which features tunable primary particle sizes and shape, is employed to prepare the mesoporous Fe-N/C catalysts with different shapes. Platelet SBA-15, irregular KIT-6, and spherical silica particle (SSP) were selected as a template to generate three different kinds of shapes of the mesoporous Fe-N/C catalyst. Physicochemical properties of mesoporous Fe-N/C catalysts are characterized by using small-angle X-ray diffraction, nitrogen adsorption-desorption isotherms, and scanning electron microscopy images. According to the electrochemical evaluation, there is no morphological preference of mesoporous Fe-N/C catalysts toward the ORR activity with half-cell configuration under alkaline electrolyte. By implementing X-ray photoelectron spectroscopy analysis of Fe and N atoms in the mesoporous Fe-N/C catalysts, it is possible to verify that the activity towards ORR highly depends on the portions of "Fe-N" species in the catalysts regardless of the shape of catalysts. It was suggested that active site distribution in the Fe-N/C is one important factor towards ORR activity.