• BMB Reports
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• v.47 no.4
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• pp.184-191
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• 2014

Respiratory syncytial virus (RSV) is the leading cause of respiratory infection in infants and young children. Severe clinical manifestation of RSV infection is a bronchiolitis, which is common in infants under six months of age. Recently, RSV has been recognized as an important cause of respiratory infection in older populations with cardiovascular morbidity or immunocompromised patients. However, neither a vaccine nor an effective antiviral therapy is currently available. Moreover, the interaction between the host immune system and the RSV pathogen during an infection is not well understood. The innate immune system recognizes RSV through multiple mechanisms. The first innate immune RSV detectors are the pattern recognition receptors (PRRs), including toll-like receptors (TLRs), retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), and nucleotide-biding oligomerization domain (NOD)-like receptors (NLRs). The following is a review of studies associated with various PRRs that are responsible for RSV virion recognition and subsequent induction of the antiviral immune response during RSV infection.

• Proceedings of the KSR Conference
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• 2010.06a
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• pp.1430-1436
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• 2010

Tubular member is hollow and is an excellent source of structural member with great buckling resistance and tortional resistance. With its development and simplicity in structure, steel tubular truss has the ability to be structured in long span bridges, without a stiffener. Recently, it has been used in many countries in Europe, Canada, Japan, and the US with the help of international committees such as CIDECT(International Committee for the Development and Study of Tubular Structures and International Institute of Welding). The most important problem when using the tubular member is the fact that it is difficult to test the fatigue stress determined by nominal stress, since geometrical stress concentration occurs due to the welded joint's nod of complexity. The purpose of this study is to compare and examine current theories and widely applied Hot Spot stress determinations through finite element analysis, which is about welded joints of steel tubular truss. We would like to suggest a way of design practice which involves a bridge plan with rarely domestically used steel tubular truss` basic research data as well as considering the future of tubular member.

• Journal of Ginseng Research
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• v.11 no.1
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• pp.84-89
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• 1987

The contents of some chemical constituents in several parts of Panax ginseng were investigated. Each part of ginseng was extracted with 70% ethanol and then water. The yield of extract was the highest in fine root, and relatively low in roughly dried ginseng and white ginseng, On the other hand, the contents of total sugars in white ginseng and seedling ginseng were high, but low in leaf and peel. The contents of crude protein in roughly dried ginseng and white ginseng were high, but those in leaf, rhizome (nod) and peel were low. The content of crude fat was higher in leaf than in other parts of ginseng plants and that was the lowest in fine root. Among free sugars, the content of fructose was high in leaf and rhizome, but that was the lowest in fine root. In the case of glucose content, leaf contained the highest amount, but fine root did the lowest. Sucrose contents in white, roughly dried and lateral roots were high, whereas that in leaf was low.

• Journal of Internet Computing and Services
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• v.2 no.3
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• pp.71-79
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• 2001

In Incremental attribute evaluation algorithm, a new input attribute is exact1y compared with a previous input attribute tree, and then determine which subtrees from the old should be used in constructing the new one. In this paper incremental attribute evaluation algorithm was used to make incremental evlauation of hierarchical attribute grammar more efficient1y, and reconstructing the incremental attribute evaluation algorithm by analyzing that of Carle and Pollock, finally the incremental attribute evaluation algorithm for optimalized attribute tree d' copy was constructed by applying element of attribute !ree dcopy to a new attribute tree d' copy. Also proving that how the reused nod and type of defined parameter in input program carried out the incremental attribute evaluation by using that algorithm.

• Molecules and Cells
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• v.25 no.4
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• pp.487-493
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• 2008

HoxB4 has been shown to enhance hematopoietic engraftment by hematopoietic stem cells (HSC) from differentiating mouse embryonic stem cell (mESC) cultures. Here we examined the effect of ectopic expression of HoxB4 in differentiated human embryonic stem cells (hESCs). Stable HoxB4-expressing hESCs were established by lentiviral transduction, and the forced expression of HoxB4 did not affect stem cell features. HoxB4-expressing hESC-derived CD34+ cells generated higher numbers of erythroid and blast-like colonies than controls. The number of CD34+ cells increased but CD45+ and KDR+ cell numbers were not significantly affected. When the hESC derived CD34+ cells were transplanted into $NOD/SCID{\beta}2m-/-$ mice, the ectopic expression of HoxB4 did not alter their repopulating capacity. Our findings show that overexpression of HoxB4 in differentiating hESCs increases hematopoietic colony formation and hematopoietic cell formation in vitro, but does not affect in vivo repopulation in adult mice hosts.

• Proceedings of the Korea Institute of Convergence Signal Processing
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• 2006.06a
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• pp.49-52
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• 2006

오늘날 컴퓨터의 발달과 인터넷의 확산으로 멀티미디어 컨텐츠의 보급이 급격히 확대되고 있으며, 이들 컨텐츠에는 원거리 화상회의, 감시시스템, 주문형 비디오(VOD), 주문형 뉴스(NOD), 디지털 편집 시스템 등 동영상이 포함되어 있다. 이처럼 동영상은 정보교환과 정보표현의 매개물로서 중요한 역할을 한다. 그러나 이와 같은 동영상은 노이즈나 전송과정 중 발생하는 문제 등으로 인해 항상 좋은 품질을 보장되지 않는다. 이런 훼손된 영상을 원영상으로 복원하거나 사용자가 제거 혹은 복원하고자 하는 영역을 지정 처리함으로서 다양한 정보를 획득할 수 있다. 일반적으로 pc에서 사용되어지는 대부분의 동영상은 $15fps{\sim}30fps$이다. 대부분의 동영상 편집 기술은 각각의 frame을 추출하여 수동적으로 처리하므로 비용과 시간이 많이 든다. 이런 단점을 해결하기 위해 여러 방법이 기존에 시도되고 있다. 제거 혹은 복원하고자 하는 영역을 전 frame에서 처리하기 위해 움직임 검출 및 추적기법이 사용되며, 제거 혹은 복원하기 위해 median filtering, image inpainting 처리 방법들이 있다. 본 연구에서는 사용자에 의해 미리 정의된 바운딩 박스내의 객체를 추적하여 객체의 중심값을 찾는 mean-shift algorithm을 이용하여 움직이는 객체를 추적하였고 image Inpainting algorithm을 이용하여 훼손된 영역을 복원하거나 제거하고자 하는 객체를 제거하였다.

• The Journal of Korean Physical Therapy
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• v.7 no.1
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• pp.51-59
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• 1995

The purpose of this study is to evaluate pain and range of motion in the frozen shoulder and to compare Hold-Relax technique with ROM exercise. Twenty-eight frozen shoulder patients between 41 nod 76 years of age were selected and were divided equally by random distribution into a Hold-Relax technique group and a ROM exercise group. To analyze the therapeutic effect between the two groups, two measurements were taken. A measurement of pain was taken by visual analogue scale and a measurement of range of motion was taken by measuring flexion and abduction degrees with a goniometer. The results were as followings : 1. The Hold-Relax group is more effective in decreasing the pain than the ROM exercise group. 2. The Hold-Relax group is more effective in increasing the range of flexion at the shoulder than the ROM exercise group. 3. The Hold-Relax group is more effective in increasing the range of abduction at the shoulder than the ROM exercise group.

• Molecules and Cells
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• v.37 no.6
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• pp.441-448
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• 2014

Inflammasomes are specialized signaling platforms critical for the regulation of innate immune and inflammatory responses. Various NLR family members (i.e., NLRP1, NLRP3, and IPAF) as well as the PYHIN family member AIM2 can form inflammasome complexes. These multiprotein complexes activate inflammatory caspases (i.e., caspase-1) which in turn catalyze the maturation of select pro-inflammatory cytokines, including interleukin (IL)-$1{\beta}$ and IL-18. Activation of the NLRP3 inflammasome typically requires two initiating signals. Toll-like receptor (TLR) and NOD-like receptor (NLR) agonists activate the transcription of pro-inflammatory cytokine genes through an NF-${\kappa}B$-dependent priming signal. Following exposure to extracellular ATP, stimulation of the P2X purinoreceptor-7 ($P2X_7R$), which results in $K^+$ efflux, is required as a second signal for NLRP3 inflammasome formation. Alternative models for NLRP3 activation involve lysosomal destabilization and phagocytic NADPH oxidase and /or mitochondria-dependent reactive oxygen species (ROS) production. In this review we examine regulatory mechanisms that activate the NLRP3 inflammasome pathway. Furthermore, we discuss the potential roles of NLRP3 in metabolic and cognitive diseases, including obesity, type 2 diabetes mellitus, Alzheimer's disease, and major depressive disorder. Novel therapeutics involving inflammasome activation may result in possible clinical applications in the near future.

• The Plant Pathology Journal
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• v.17 no.2
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• pp.67-70
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• 2001

Medicago truncatula is a diploid legume plant related to the forage crop alfalfa. Recently, it has been chosen as a model species for genomic studies due to its small genome, self-fertility, short generation time, and high transformation efficiency. M. truncatula engages in symbiosis with nitrogen-fixing soil bacterium Rhizobium meliloti. M. truncatula mutants that are defective in nodulation and developmental processes have been generated. Some of these mutants exhibited altered phenotypes in symbiotic responses such as root hair deformation, expression of nodulin genes, and calcium spiking. Thus, the genes controlling these traits are likely to encode functions that are required for Nod-factor signal transduction pathways. To facilitate genome analysis and map-based cloning of symbiotic genes, a bacterial artificial chromosome library was constructed. An efficient polymerase chain reaction-based screening of the library was devised to fasten physical mapping of specific genomic regions. As a genomics approach, comparative mapping revealed high levels of macro- and microsynteny between M. truncatula and other legume genomes. Expressed sequence tags and microarray profiles reflecting the genetic and biochemical events associated with the development and environmental interactions of M. truncatula are assembled in the databases. Together, these genomics programs will help enrich our understanding of the legume biology.

• Resources Recycling
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• v.5 no.2
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• pp.45-51
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• 1996

Domestic coal contains approximnlely 03 to 7 percentage of sulfur. When the suliur in coal is burned, exhaust gas , nay be thc causc of air pollution problcms as well as acid rain. Thc government dccideil lo strengthen the environmcnlal protection policy a1 the 270 ppm of SO, for the coal-Ered plants and to stari in Ian. 1, 1999. This study was carried out lo rcmove the stlfur and mineral mancrs in the samplw using wet msg~xiic separatol ant1 oil agglomeration apparatus. The rcsults for the wet magnetic separalion showed that the total sulfur removal from Kangnung coal sample was 60.8% with 82.6% combustible recovery. For the results of oil agglomeration testa, combustible recavety, ash nod sulfur rcmovcl horn Maro coal sample were 98.0, 70.9 and 95.7 percent, respectively.