• Journal of the Korean Society of Clothing and Textiles
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• v.14 no.1 s.33
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• pp.3-12
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• 1990

The purposes of this study were to determine the consumer dissatisfaction factors in the process of purchase and use of clothing, and to investigate the relationships between the dissatisfaction factors and selected variables-clothing importance, evaluative attributes, price, shopping stores. The research questionnaires selected from the pilot study were administered to 547 female subjects in the age of twenties. The dissatisfaction factors identified as a result of the factor analysis were as follows: (1) 'price' factor ($21.6\%$ of the total explained variance), (2) 'product assortment' factor ($21.5\%$), (3) 'purchase decision-making' factor ($19.9\%$), (4) 'quality' factor ($18.6\%$), (5) 'informa­tion and service' factor ($18.4\%$). By these five factors, the $34.7\%$ of the total variance were explained. The factors were validated by the multiple regression analysis. The purchase decision­making factor has the greatest explanatory power suggests that psychological aspects are more important to clothing dissatisfaction than any other objective aspects. The relationships between the dissatisfaction factors and the selected variables were found to be as follows: 1) The higher clothing importance scores, the higher product assortment related dissatisfac­tion score. 2) The higher the purchase price, the lower the price related dissatisfaction, but the higher the product assortment related dissatisfaction scores. 3) The department store and the national brand chain store shoppers had higher product assortment related dissatisfaction compared to the small retail store and discount store shoppers.

• Reproductive and Developmental Biology
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• v.36 no.2
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• pp.121-131
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• 2012

After spermatogenesis, spermatozoa come in contact with fluids in the epididymis where they mature. During ejaculation, spermatozoa are mixed with secretions from prostate gland, vesicular glands, and bulbourethral glands. During natural mating, seminal plasma is deposited in the female reproductive tract eliciting various physiological and immunological responses. With the advances in proteomics, the components of seminal plasma have been identified and the information may be valuable in identifying markers for fertility. Components of seminal plasma that affect fertility have been discovered and the mechanism of action of these factors has been determined. The objective of this study was to determine the specific seminal plasma proteins from Korean native cattle, Hanwoo, and Korean native brindle cattle (KNBC) with the long term goal of improving fertilization rate. After SDS-PAGE and 2-dimensional gel electrophoresis, proteins were identified by Q-ToF analysis. They include plasma serine protease inhibitor precursor and platelet-activating factor acetylhydrolase after SDS-PAGE. Number and density of the spots in 2-dimensional gels were higher in KNBC than Hanwoo. Proteins identified from the paired spots of both breeds include chain A, bull seminal plasma PDC-109 Fibronectin Type II module, BSP-30 kDa precursor, and Spermadhesin Z13 or its precursor. Interestingly, some proteins were identified from multiple spots. The functional differences of these diverse forms of the proteins may require further studies. With their previously reported roles in sperm capacitation by these proteins, the studies on the mechanism of action, ligand interaction and the variation in the genome may help improving fertility in cattle.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.1B
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• pp.1-8
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• 2012

In this paper, we propose an algorithm to improve collision avoidance in Vehicle-to-Vehicle (V2V) networks based on IEEE 802.11p. Since IEEE 802.11p adopts CSMA/CA as a multiple access scheme and an emergency warning message (EWM) is delivered to behind vehicles in a multi-hop manner, due to transmission collision, the more vehicles in the vehicle chain results in a longer delay. The longer delay increases the possibility of a rear-end collision. In order to ensure message reception with low latency, we consider implicit acknowledgement of a broadcasted EWM message and propose an algorithm to reduce redundant message transactions, called Two-Way Implicit Acknowledgement (TWIA). By simulations, we show that our proposed algorithm can reduce the latency until the last car receives the message by 9% and the success rate every car receives the message within 0.7sec by 12% at 100 fixed-number-of-car environment.

• The Korea Journal of Herbology
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• v.31 no.5
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• pp.41-46
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• 2016

Objectives : The Skin is composed of multiple layers, including the epidermis, dermis, and hypodermis. It provides a vital barrier structure that protects vertebrates from external environmental antigens, solvents, ultraviolet light, microorganisms, toxins, and weather conditions. Although several biological effects of Mori Follium have been reported, beneficial effects of Mori Follium in skin health remain unclear. In this study, we prepared water extract of Mori Follium (MLE) and evaluated the effects on melanin accumulation and expression levels of skin fibril-related proteins.Methods : The cytotoxicities of MLE in B16F10 melanoma and human skin fibroblasts (HSF) were examined by MTT assay. Inhibitory effect of MLE on the α-MSH- and IBMX-induced melanosis in B16F10 melanoma was examined. The expression levels of fibronectin, collagen 1α2, and CCN2 in MLE-treated HSF were analyzed by reverse transcription-polymer chain reaction (RT-PCR) and western blotting.Results : The MLE treatment for 24 h did not affect to the B16F10 and HSF at concentrations of 1, 10, 50, 100, 200, 400 and 800 ㎍/ml. The MLE treatment for 72 h significantly and dose dependently suppressed melanin accumulation in B16F10 melanoma. In addition, the MLE treatment up-regulated expression levels of skin fibril-related genes such as fibronectin, collagen 1α2, and CCN2 in HSF. Our western blot analysis revealed MLE-induced up-regulation of skin fibril-related genes required the activation of CCN2 protein.Conclusions : In conclusion, these findings suggest that the MLE could be used in development of cosmetic natural material of maintaining healthy skin.

• Journal of Distribution Research
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• v.13 no.3
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• pp.127-154
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• 2008

For the large scale retailers such as chain discount stores and specialty stores, having measurement tool to maintain service quality can be very crucial to sustain high and same level of service qualities around multiple stores. This study aims to develop service quality scales of large-scale stores using Korean discount store cases. We have studied the previous service quality measures including RSQS(Retail Service Quality Scale) and have modified and developed our own scale model called KD-SQS(Korea Discount Service Quality Scale). The following six components have been revealed as the basic dimensions of service quality of Korean discount stores: basic benefits, promotion, personal interactions, physical aspects, policy and additional convenience. Our scales have been verified through various validity and reliability tests.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.3
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• pp.138-147
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• 2017

As the functions and structure of the system are complicated and elaborated, various types of structures are emerging to increase reliability in order to cope with a system requiring higher reliability. Among these, standby systems with standby components for each major component are mainly used in aircraft or power plants requiring high reliability. In this study, we consider a standby system with a multi-functional standby component in which one standby component simultaneously performs the functions of several major components. The structure of a parallel system with multifunctional standby components can also be seen in real aircraft hydraulic pump systems and is very efficient in terms of weight, space, and cost as compared to a basic standby system. All components of the system have complete operation, complete failure, only two states, and the system has multiple states depending on the state of the component. At this time, the multi-functional standby component is assumed to be in a non-operating standby state (Cold Standby) when the main component fails. In addition, the failure rate of each part follows the Weibull distribution which can be expressed as increasing type, constant type, and decreasing type according to the shape parameter. If the Weibull distribution is used, it can be applied to various environments in a realistic manner compared to the exponential distribution that can be reflected only when the failure rate is constant. In this paper, Markov chain analysis method is applied to evaluate the reliability of multi-functional multi-state standby system. In order to verify the validity of the reliability, a graph was generated by applying arbitrary shape parameters and scale parameter values through Excel. In order to analyze the effect of multi-functional multi-state standby system using Weibull distribution, we compared the reliability based on the most basic parallel system and the standby system.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.3
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• pp.251-258
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• 2010

This paper presents the technology for the design, fabrication, and characterization of a microfluidic system interface (MSI); the purpose of this technology is to enable the integration of complex microfluidic systems. The MSI technology can be applied in a simple manner for realizing complex arrangements of microfluidic interconnects, integrated microvalves for fluid control, and optical windows for on-chip optical processes. A microfluidic system for the preparation of genetic samples was used as the test vehicle to prove the effectiveness of the MSI technology for packaging complex microfluidic systems with multiple functionalities. The miniaturized genetic sample preparation system comprised several functional compartments, including compartments for cell purification, cell separation, cell lysis, solid-phase DNA extraction, polymerase chain reaction, and capillary electrophoresis. Additionally, the functional operation of the solid-phase extraction and PCR thermocycling compartments was demonstrated by using the MSI.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.38 no.3
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• pp.136-148
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• 2015

We analyzed the effect of three different types of inventory systems for saving the total cost using simulation on the system where multiple depots and many retailers disperse on the limited area. Three types of inventory systems are single echelon system with inventory exchange and two-echelon system and the variant two-echelon system. Variant two echelon system is the two-echelon system where the inventory transshipmentsare allowed on every two stage inventory echelons. Inventories kept on every retailer are commonly used for all retailers when certain retailer has stock-out. And when all retailers are stock-out, inventories kept on every depot are commonly used for the retailers whose assigned depots are stock-out. These all three systems are simulated with the constraint of service level on wide range of parameter settings. Simulation results show that cost saving effect appear clear for single echelon system and two-echelon system when shortage cost portion and transportation cost portion becomes large respectively irrespective of depot number. Variant two echelon system seems to be superior to two other systems when transportationcost portion becomes very small. But this superiority is not proved in terms of statistics. So we may conclude that the variant two echelon system may be useless with the higher administrative efforts due to frequent inventory exchange. Also we note that the traditional two echelon system becomes inferior to two other systems in terms of statistics when service level becomes high or when demand variance becomes very large. And inventory integration effect that cost becomes saved when depot number decrease, diminishes when transportation cost or stock-out cost increases irrespective of inventory systems.

• The Journal of Society for e-Business Studies
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• v.15 no.1
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• pp.157-171
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• 2010

To effectively maintain manufacturing collaboration, the development of effective performance measurements for the collaboration is required. Most existing key performance indicators however were developed to measure the performances of internal activities or outsourcing of a company. For that reason, it is necessary to devise new key performance indicators that the partners participating in the collaboration can arrange and compromise with each other to reflect their common goals. In this paper, we propose collaborative Key Performance Indicators(cKPIs), which is used to measure the collaboration work of multiple manufacturing partners on the basis of the Supply Chain Operations Reference(SCOR) model. Also, a modified Sigmoid function is devised as a desirability function to reflect the characteristics of Service Level Agreement(SLA) between two partners. The proposed indicators and the desirability functions can be utilized to perform and maintain the successful collaboration by providing a way to the quantitative measurement.

• Molecules and Cells
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• v.41 no.8
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• pp.799-807
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• 2018

Emerging evidence has suggested that cellular crosstalk between RNF168 and poly(ADP-ribose) polymerase 1 (PARP1) contributes to the precise control of the DNA damage response (DDR). However, the direct and reciprocal functional link between them remains unclear. In this report, we identified that RNF168 ubiquitinates PARP1 via direct interaction and accelerates PARP1 degradation in the presence of poly (ADP-ribose) (PAR) chains, metabolites of activated PARP1. Through mass spectrometric analysis, we revealed that RNF168 ubiquitinated multiple lysine residues on PARP1 via K48-linked ubiquitin chain formation. Consistent with this, micro-irradiation-induced PARP1 accumulation at damaged chromatin was significantly increased by knockdown of endogenous RNF168. In addition, it was confirmed that abnormal changes of HR and HNEJ due to knockdown of RNF168 were restored by overexpression of WT RNF168 but not by reintroduction of mutants lacking E3 ligase activity or PAR binding ability. The comet assay also revealed that both PAR-binding and ubiquitin-conjugation activities are indispensable for the RNF168-mediated DNA repair process. Taken together, our results suggest that RNF168 acts as a counterpart of PARP1 in DDR and regulates the HR/NHEJ repair processes through the ubiquitination of PARP1.