• Journal of KIISE:Software and Applications
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• v.30 no.12
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• pp.1208-1219
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• 2003

The Internet has become a part of our life and has changed our living environments dramatically. However, Electronic Commerce (EC) stays currently at a level that a buyer deals only with an one-sided condition (price) proposed by a seller or compares the proposed condition to find a better one. As the agent technology makes progress, EC requires negotiation that is not one-sided but is a way to maximize profits of both seller and buyer. Moreover, negotiation in EC should consider multiple issues rather than a single issue to replace the traditional commerce. In this paper we propose a negotiation model, which guarantees balanced profits between two agents through negotiation using multi-issues, and makes a deal successfully under time-constraint environment. The proposed negotiation model suggests strategies(alternative and simultaneous strategy) that change the value of issues with each agent has time for negotiation. In this paper, we also suggest a strategy that proposes an offer to each other. We compare the proposed negotiation model with another negotiation model. The experimental results show that dynamic conceder tactic and linear tactic showed balanced profits and a high percentage of deals for negotiation between two agents, and the sum of utilities of two agents is high, when the alternative strategy is used.

• Journal of Electrical Engineering and Technology
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• v.8 no.6
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• pp.1559-1570
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• 2013

The family of ISO/IEEE11073 standards is the basis of the e-health system and provides interoperability for personal health devices. In the early stage of e-health business, it was expected that people would use a health device individually. In this case, a measurement datum was episodically acquired and generally transmitted for one person at a time. Recently, a health device is expected to be used by multiple people, and large amounts of measurement data are gathered in a short time interval. In addition, mobile health devices have become more popular, so that energy efficient measurement data transmission is required, to prolong the use of a device. In IEEE11073 PHD standards, data transmission is classified into three different types: immediate individual transfer, small block transfer, and large block transfer. The large block transfer using PM-store concept provides efficient transmission. However, an existing PM-store has problem when a device is used by multiple people. To address the defined problem, a modified PM-segment that is in compliance with 11073 standards is proposed in this paper. In particular, the proposed PM-segment is designed to minimize the additional complexity of an agent instead of a manager and it is interoperable with the existing manager. The proposed PM-segment shows better performance than the existing PM-segment, in terms of memory requirements and expected queue time. Also, performance comparison among the three transfers is performed in regard to the delay time and communication power consumption points of view.

• Journal of the Korean Ceramic Society
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• v.52 no.6
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• pp.497-501
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• 2015

Inkjet printing is a widespread technology, offering advantages such as high-quality decoration, a continuous process, and the accurate direct reproduction of patterns or pictures. In inkjet printing technology, the dispersion stability of ceramic ink is one of the most important factors. In this study, the dispersion stability of blue $CoAl_2O_4$ ink for ceramic inkjet printing is systematically investigated. Blue $CoAl_2O_4$ pigment was synthesized by a solid-state reaction and then milled to less than 300nm in size. In order to investigate the influence of the viscosity on the dispersion stability, two types of $CoAl_2O_4$ ceramic inks (termed here Blue L and Blue H) were prepared using different volume ratios of ethylene glycol and ethanol. The Blue L and Blue H ink solutions contained cetyltrimethylammonium bromide(CTAB) as a dispersive agent. The viscosity, surface tension and jetting stability of the $CoAl_2O_4$ ceramic inks were analyzed using a rheometer, a surface tension meter and a dropwatcher. The dispersion stability of the $CoAl_2O_4$ ceramic ink was investigated by a multiple light-scattering method. Blue H, a ceramic ink with higher viscosity, showed much better dispersion stability than the Blue L ceramic ink.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.49 no.1
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• pp.13-19
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• 2016

A total of 423 shellfish (Oysters, Crassostrea gigas; short-necked clams, Ruditapes philippinarum and corb shells, Cyclina sinensis) were collected from the west coast of Korea, from which 277 Escherichia coli strains were isolated. The antimicrobial susceptibility patterns of isolated strains were analyzed for 22 antimicrobial agents used in Korea for clinical or veterinary therapy. The resistance of E. coli isolates to ampicillin (37.2%) was highest, followed by cephalothin (21.7%), cefazolin (19.9%), trimethoprim (15.2%). Antimicrobial resistance was present in 56.7% of E. coli isolates against at least one antimicrobial agent. Of 277 isolates, 44 (15.9%) were resistant to multiple antimicrobial agents.

• Korean Journal of Pharmacognosy
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• v.33 no.4 s.131
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• pp.337-342
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• 2002

The effect of water extract composed of panax ginseng radix rubra, acanthopanacis cortex, and cordyceps (PAC) on diabetic animal models were investigated in two different diabetic animal models. FAC water extract significantly reduced the plasma glucose levels on day 30 as compared with the diabetic control group in $KKA^Y$ obese, hyperglycemic and hyperglycemic and hyperinsulinemic mice, and also reduced the plasma glucose levels as well as total cholesterol in multiple low dose (MLD) strep tozotocin-induced diabetic SD rats. PAC water extract also showed an inhibitory effect on reduction of body weight and on development of MLD STZ-induced diabetic state. Elevated kidney hypertrophy, which is a characteristic feature shown in early stage of diabetic nephropathy and calculated as the ratio of kidney mass (g) relative to the body weight (g), was also markedly improved in PAC water extract- treated group as compared to the diabetic control group. Taken together, these data suggest that PAC water extract may have a potential as a antidiabetic agent in type 2 diabetes mellitus.

• Restorative Dentistry and Endodontics
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• v.26 no.2
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• pp.153-161
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• 2001

The purpose of this study was to evaluate microleakage of six current dentin bonding systems. In this in vitro study, class V cavities were prepared on buccal and lingual surfaces of thirty extracted human molars. Each margin was on enamel and dentin/cementum. Experimental teeth were randomly divided into six groups of 5 each. Group 1 : Scotchbond Multi-Purpose; Group 2 : Single Bond; Group 3 : Prime&Bond NT ; Group 4 : Clearfil Liner Bond 2 ; Group 5 : MAC Bond II ; Group 6 : One-up Bond F. The bonding agent and composite resin were applied to class V cavities according to manufacturer's directions. After thermocycling, the specimens were immersed in 0.5% basic fuchsin dye solution for 6 hours and sectioned longitudinally through the center of the restoration with a low speed diamond saw. The degree of microleakage was measured as the extent of dye penetration under the stereomicroscope at $\times$20. The data were analyzed using one way ANOVA. When significant differences found. multiple comparisons were made using Duncan's Multiple Range Test. The results of this study were as follows: 1. In all groups, leakage value seen at the enamel margin was significantly lower than that seen at the dentin margin(P<0.001). 2. At the enamel margin, none of the dentin bonding systems used in this study showed statistically significant difference in leakage values(P<0.05). 3. At the cementum margin, group 3 showed the highest leakage value, and others were decreased as group 5, 6, 4 in that order, and group 1, 2 showed the lowest leakage value. There was statistically significant difference between group 3 and the other groups except for group 5(P<0.05).

• International Journal of Advanced Culture Technology
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• v.8 no.2
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• pp.1-5
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• 2020

As the world gradually advances to an aging society, the quality of human life is valued. Among them, 'quality of sleep' is very closely related to quality of life. Recently, Korea expanded health insurance coverage for "sleep disorders". Particularly, as the number of sleep multiple tests and prescriptions for sleep aids has increased rapidly, much attention has been focused on the related medical service environment. Therefore, this study looked at an in-depth interview of 11 hospitals to see what treatment delivery system is being established when the government applies health insurance for 'sleep disorders'. In conclusion, the organizations with the most average number of sleep polyp tests per day were found to have more sleep polyp labs (hardware) and more full-time specialists. Also, the polysomnography lab (hardware) and the specialist's full-time status (software) did not necessarily result in a "positive pressure regulator prescription" that can solve "sleep apnea" caused by "sleep ailments". Rather, it was found that the number of days of sleep multiple laboratories (hardware), the number of full-time specialists (software) or the specialty majors (software) had a greater impact. In particular, the higher the specialist's full-time personnel (software) index (=6.000), the higher the sleep-inducing agent prescription rate(=1.000), and the lower the specialist's full-time personnel (software) index (=1.000), the higher the sleep-inducer's prescription rate(= 0.010) Was low. In addition, even if the professional full-time personnel(software) index was the same (=1.000), the hospital type was lower as it was closer to the public hospital(=0.067) and higher at the specialized hospital (= 0.933). In the case of university hospitals, when the full-time specialists (software) are in the same condition (= 1.000), the frequency of use of the sleep laboratory (=1.000) and the sleep test rate (= 1.000) were all the same.

• Proceedings of the Korean Society of Crop Science Conference
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• 2019.09a
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• pp.19-19
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• 2019

It is necessary to maintain stable crop productions under the unsuitable environments, because the drought and flood may be frequently caused by the global warming. Therefore, it is agent to improve the crop growth model corresponded to soil moisture status. Chili pepper (Capsicum annuum) is one of the useful crop in Asia, and then it is affected by change of precipitation in consequence drought and flood occur however crop model to evaluate water stresses on chili pepper is not enough yet. In this study, development of crop model under different soil moisture status was attempted. The experiment was conducted on the slope fields in the greenhouse. The water level was kept at 20cm above the bottom of the container. Habanero (C. chinense) was used as material for crop model. Sap bleeding rate, SPAD value, chlorophyll content, stomatal conductance, leaf water potential, plant height, leaf area and shoot dry weight were measured at 10 days after treatment (DAT) and 13 DAT. Moreover, temperature and RH in the greenhouse, soil volume water contents (VWC) and soil water potential were measured. As a result, VWC showed 4.0% at the driest plot and 31.4% at the wettest plot at 13 DAT. The growth model was calculated using WVC and the growth analysis parameters. It was considered available, because its coefficient of determination showed 0.84 and there are significant relationship based on plants physiology among the parameters and the changes over time. Furthermore, we analyzed the important factors for higher accuracy prediction using multiple regression analysis.

• Biomolecules & Therapeutics
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• v.30 no.1
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• pp.80-89
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• 2022

The targeting of DNA methylation in cancer using DNA hypomethylating drugs has been well known to sensitize cancer cells to chemotherapy and immunotherapy by affecting multiple pathways. Herein, we investigated the combinational effects of DNA hypomethylating drugs and ionizing radiation (IR) in human sarcoma cell lines both in vitro and in vivo. Clonogenic assays were performed to determine the radiosensitizing properties of two DNA hypomethylating drugs on sarcoma cell lines we tested in this study with multiple doses of IR. We analyzed the effects of 5-aza-dC or SGI-110, as DNA hypomethylating drugs, in combination with IR in vitro on the proliferation, apoptosis, caspase-3/7 activity, migration/invasion, and Western blotting using apoptosis- or autophagy-related factors. To confirm the combined effect of DNA hypomethylating drugs and IR in our in vitro experiment, we generated the sarcoma cells in nude mouse xenograft models. Here, we found that the combination of DNA hypomethylating drugs and IR improved anticancer effects by inhibiting cell proliferation and by promoting synergistic cell death that is associated with both apoptosis and autophagy in vitro and in vivo. Our data demonstrated that the combination effects of DNA hypomethylating drugs with radiation exhibited greater cellular effects than the use of a single agent treatment, thus suggesting that the combination of DNA hypomethylating drugs and radiation may become a new radiotherapy to improve therapeutic efficacy for cancer treatment.

• Mycobiology
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• v.45 no.1
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• pp.39-43
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• 2017

Leaf spot disease on black chokeberry (Aronia melanocarpa) was observed at several locations in Korea during 2014-2015. Leaf spots were distinct, scattered over the leaf surface and along the leaf border, subcircular to irregular and brown surrounded by a distinct dark color, and were expanded and coalesced into irregularly shaped lesions. Severely infected leaves became dry and fell off eventually. The causative agent was identified as Pseudocercospora pyricola. Morphological observations and phylogenetic analyses of multiple genes, including internal transcribed spacer, translation elongation factor 1-alpha, actin, and the large subunit ribosomal DNA were conducted. The pathogenicity test was conducted twice yielding similar results, fulfilling Koch's postulates. To our knowledge, this is the first report on P. pyricola infection of A. melanocarpa globally.