• 멤브레인
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• 제6권3호
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• pp.182-187
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• 1996

우수한 분획특성을 가지는 친수성 고분자인 poly(acrylonitrile) [PAN]을 막소재로 하여 상전환법(phase inversion method)으로 복합막의 지지층으로 사용될 지지막을 제조하였으며, 한외여과 실험을 통하여 지지막의 특성인 순수 투과도와 분획분자량을 측정하였다. 이 지지막 표면에 poly(acrylic acid) [PAA]를 dip-coating 시켜 열처리한 복합막을 제막하고 에탄올 수용액의 투과증발 분리특성을 고찰하였다. PAN 지지막의 UF 특성은 순수의 투과유속이 $0.17~31\textrm{mm}^3/m^{2} \cdot s \cdot Pa$, 분획분자량이 42,000~150,000의 막을 얻었다. 복합막의 투과유속과 분리계수는 지지막의 기공구조 변화에 상당한 영향을 받고 있음을 알 수 있으며, 지지층의 분획분자량의 증가에 따라 투과유속은 감소하였고 분리계수는 공급원액의 농도에 따라 약간의 변화를 보였다.

• 한국막학회:학술대회논문집
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• 한국막학회 2002년도 추계 총회 및 학술발표회
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• pp.131-134
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• 2002

• 한국염색가공학회지
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• 제15권2호
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• pp.68-75
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• 2003

In this work, ultrafiltration(UF) membranes were prepared using polyethersulfone(PES). The polymer was dissolved in various solvent, such as N, N-dimethyl formamide(DMF), N,-dimethyl acetamide (DMAc), N,N-dimethyl sulfoxide(DMSO) and N-methyl-2- pynolidone(NMP). Each polymer solution was casted on the glass plate, and immersed into non-solvent bath. In this way finely porous UF membranes were prepared by phase inversion method. The cross sectional structure of PES membrane was asymmetric which was consist of sponge-like sublayer, finger-like toplayer, and active skin layer. From the solute rejection experiments, the molecular weight cut off of the prepared membrane in various solvent was evaluated 10,000 for DMF, 30,000 for DMAc, 50,000 for DMSO, and 10,000 for NMP respectively.

• 한국염색가공학회지
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• 제17권3호
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• pp.34-42
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• 2005

In this work, a practical separation performance was investigated on aqueous alcohol solutions, especially for iso-propyl alcohol (IPA), which is usually used during the semi- conductor rinsing process. The removal of various substances from waste aqueous IPA solutions was carried out by microfiltration with $0.1\~1{\mu}$m pore size of mean diameter as a pre-filter. Permeability and molecular weight cut-off of the functional polysulfone(PSf) ultrafiltration membrane to purify waste aqueous IPA solutions were measured through the ultrafiltration test. The solute rejection of PSf membrane had $92\%$ in 1,000ppm aqueous PEG solution with PEG molecular weight 10,000, the molecular weight cut-off had 10,000. The IPA concentration on the $CMPA-K^+$ membrane performance using pervaporation module system could be increased from $95.04 wt\%$ to more than $98.50wt\%$ in about 9hr at operation temperature of $70^{\circ}C$ using the pervaporation module system.

• 멤브레인
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• 제13권4호
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• pp.211-218
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• 2003

생분해성 음이온 계면활성제인 deoxycholic acid(DCA)의 미셀을 이용한 한외여과에서 카드뮴의 제거 특성을 살펴보았다. 본 연구에서는 교반 한외여과 셀을 사용하였으며, 한외여과 막은 분획분자량(molecular weight cut-off)이 서로 다른 Millipore사의 YM1, YM3, YM10 및 YM30을 사용하였다. DCA와 카드뮴의 혼합용액에서 DCA의 임계미셀농도는 순수 DCA 용액에서 보다 낮아지고, 미셀의 크기는 증가되었다. 카드뮴이온의 제거율은 사용한 막의 분획분자량에 의해서는 거의 영향이 없었으나, 카드뮴이온에 대한 DCA의 몰 비의 증가에 따라서는 급격히 증가하였다. 카드뮴이온에 대한 DCA의 몰 비가 3일 때 카드뮴이온의 제거율은 사용한 막에 관계없이 99.6% 이상이었다. 순수 투과플럭스에 대한 혼합용액의 투과플럭스의 비로 정의한 상대 투과플럭스는 YM3 > YM1 > YM10 > YM30 막의 순서로 감소하였다.

• Journal of Nutrition and Health
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• 제29권2호
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• pp.153-158
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• 1996

Polyethylene glycols(PEGs)are hydrophilic molecules that have been used to characterize intestinal permeability via the paracellular pathway. Using a mixture of PEGs(400, 600 and 1000), containing oligomers in the molecular weight range 330 to 1122 D, the molecular weight permeability dependence in the jejunum of the rat small intestine was examined, employing an in situ recirculation perfusion technique. Individual oligomers were determined by HPLC with refractive detection. In the range studied, a distinct molecular weight cut-off was not apparent. Corrected for the length of jejunum used in the study, over the molecular weight range 330 to 1122D, the apparent permeability(Papp) of PEG ranged from 4.92$\pm$0.02$\times$10-5cm/sec(mean$\pm$SEM, n=5) to 0.28$\times$10-5cm/sec. Also, it was observed that the apparent permeability was inversely proportional to approximately MW2. The results in this study suggest that molecular weight is an important factor in determining the intestinal permeability.

• KSBB Journal
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• 제13권5호
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• pp.535-539
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• 1998

The monellin, a sweet-taste protein, was expressed and secreted in Saccharomyces cerevisiae. The secreted menellin was concentrated using an ultrafiltration membrane with a nominal molecular weight cut off of 3,000 or by ammonium sulfate precipitation. The monellin was purified by G-25 gel filtration chromatography, followed by CM-Sepharose ion exchange chromatography. The purified monellin was characterized by SDS-PAGE (SDS-Polyacrylamide Gel Electrophoresis) and PHLC. The molecular weight of monellin was found to be 10,700 dalton, and its purity was over 95%.

• 멤브레인
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• 제13권2호
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• pp.81-87
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• 2003

한외여과막의 분획분자량을 결정하기 위하여 dead-end형 셀내에 평막을 설치하고 분자량 분포가 수천 내지 수백만의 혼합 dextran 수용액으로 투과 실험하였다. 원료 용액과 투과액을 GPC로 분석하여 각 분자량에 대한 배제율을 구하고 90% 배제율에 해당하는 dextran분자량을 분획분자량를 결정하였다. 투과압력을 0.5에서 2.0 bar까지 증가시킬 경우, Millipore사의 PBTK막은 63,000 내지 68,000 daltons로 10% 이내에서 변화하였지만 Millipore사의 PBQK 막 또는 (주)새한의 UE1812막의 분획분자량은 각각 3.5 및 4.3 배 증가하였다. 또한 투과액을 원료용액의 10내지 40%까지 분리막을 증가시키면서 배제율을 측정한 결과, PBTK의 분획분자량은 25% 증가하였다.

• 대한의용생체공학회:의공학회지
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• 제14권3호
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• pp.227-234
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• 1993

Hemofilter was optimally designed and manufactured using polysulfone hollow fiber mem- brane with surface area of 0.6mE Molecular weight cut-off of the hemofilter was measured with polyethylene glycol and dextran aqueous solutions of various molecular weights and it was ranged from 9,500 to 38,900. Ultrafiltration rates were measured with pure water in a static system and flowing system. The clearance of urea, creatinlne, and vitamine BIB were measured using aqueous solutions.

• Fisheries and Aquatic Sciences
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• 제16권4호
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• pp.237-242
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• 2013

We investigated the antioxidant and angiotensin I converting enzyme (ACE) inhibitory activities of red snow crab Chionoecetes japonicas shell (RSCS) hydrolysate by enzymatic hydrolysis and its molecular weight cut-off fractions. The RSCS hydrolysate was fractionated through two ultrafiltration membranes of 3 and 10 kDa cut-offs. Three fractions (<3 kDa, 3-10 kDa, and >10 kDa) were evaluated for total amino acid composition, antioxidant activities using 2'-azino-bis[3-ethylbenzthiazoline-6-sulfonic acid] ($ABTS^+$) radical scavenging and superoxide dismutase (SOD)-like activities and reducing power assays, and ACE inhibitory activity using Hou's method. Although all fractions showed activity, the <3 kDa fraction of RSCS hydrolysate exhibited the greatest $ABTS^+$ radical scavenging, SOD-like and ACE inhibitory activities. However, these fractions exhibited low reducing power. These results suggest that the low-molecular-weight enzymatic hydrolysate of RSCS could be used as a functional ingredient to control oxidative stress and ACE activity.