• Journal of Life Science
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• v.21 no.11
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• pp.1526-1531
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• 2011

Local protein synthesis in neuronal dendrites is important for site-specific regulation of synaptic plasticity. In this study, we investigated whether translation initiation factors (eIFs) are present at the postsynaptic sites. High resolution confocal microscopy showed that the eIF4E and eIF4G (which bind the 5'-terminal mRNA cap), eIF5 (which is important during the 3' direction scanning to find an initiation codon), eIF6 (which mediates upregulation of translation by external stimuli), and eIF5A (which mediate translation upregulation under adverse conditions) were localized to the post-synaptic sites. Immunoblot and detergent extraction experiments also indicated that these eIFs were present in the synapse in association with the postsynaptic density (PSD). Our data provide evidence for the strategic positioning of eIFs at the postsynaptic site for initiation of translation in diverse situations.

• Journal of the Korean Data and Information Science Society
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• v.26 no.6
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• pp.1259-1269
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• 2015

Recently, big data is positioning as a keyword in the academic circles. And usefulness of big data is carried into government, a local public body and enterprise as well as academic circles. Also they are endeavoring to obtain useful information in big data. This research mainly deals with analyses of box office success or failure of films using text mining. For data, it used a portal site 'D' and film review data, grade point average and the number of screens gained from the Korean Film Commission. The purpose of this paper is to propose a model to predict whether a film is success or not using these data. As a result of analysis, the correct classification rate by the prediction model method proposed in this paper is obtained 95.74%.

• Nuclear Engineering and Technology
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• v.52 no.10
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• pp.2410-2414
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• 2020

Heavy ions have a high potential for destroying deep tumors that carry the highest dose at the peak of Bragg. The peak caused by a single-energy carbon beam is too narrow, which requires special measures for improvement. Here, carbon-12 (¹²C) ion with different energies has been used as a source for calculating the dose distribution in the water phantom, soft tissue and bone by the code of Monte Carlobased FLUKA code. By increasing the energy of the initial beam, the amount of absorbed dose at Bragg peak in all three targets decreased, but the trend for this reduction was less severe in bone. While the maximum absorbed dose per bone-mass unit in energy of 200 MeV/u was about 30% less than the maximum absorbed dose per unit mass of water or soft tissue, it was merely 2.4% less than soft tissue in 400 MeV/u. The simulation result showed a good agreement with experimental data at GSI Darmstadt facility of biophysics group by 0.15 cm average accuracy in Bragg peak positioning. From 200 to 400 MeV/u incident energy, the Bragg peak location increased about 18 cm in soft tissue. Correspondingly, the bone and soft tissue revealed a reduction dose ratio by 2.9 and 1.9. Induced neutrons did not contribute more than 1.8% to the total energy deposited in the water phantom. Also during ¹²C ion bombardment, secondary fragments showed 76% and 24% of primary 200 and 400 MeV/u, respectively, were present at the Bragg-peak position. The combined treatment of carbon ions with neutron or electron beams may be more effective in local dose delivery and also treating malignant tumors.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.6
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• pp.549-559
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• 2008

This study verified the limitations of commercial GPS data processing software and the applicability on precise positioning through comparing the processing results between Bernese and TGO under various conditions. To achieve the goal, we selected three nationwide station data and two smaller local data to constitute networks. By using Bernese and TGO, those networks are processed through the baseline analysis and the network adjustment. The comparative analysis was carried out, in terms of software, baseline length and network scale, observation duration, and number of fixed points. In the comparison between softwares, the scientific software was excellent in accuracy. It was confirmed that, as GPS-related technology is developed, the performance of the receiver was enhanced. And, in parallel with this, even the functionalities of the commercial software were tremendously enhanced. The difference, however, in result between the scientific and commercial software are still exist even if it is not big. Therefore, this study confirms that the scientific software should be used when the most precise position is necessary to be computed, especially if baseline vectors are big.

• The Journal of the Korea Contents Association
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• v.21 no.1
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• pp.383-393
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• 2021

This paper analyzed the marketing success factors of the Chinese musical , which entered the world musical market for the first time in the history of Chinese musicals, and investigated the positive effects of the success of on the development of Chinese musicals. First, five important elements of musical marketing were determined as the analysis criteria and through this, we were able to derive that the marketing promotion was achieved by establishing a systematic strategy in the techniques of 'positioning', 'ticket promotion', 'PR strategy', 'producer', 'OSMU' as the success factors of the musical . The case of in Chinese musicals can be regarded as the first successful case by professional marketing. Due to the results of these achievements, the Chinese government and local musical support systems were established, and in recent years, Chinese musicals have been qualitative. It has been confirmed that Chinese musicals are growing rapidly in recent years in terms of quality and industry. It is expected that more academic studies related to Chinese musicals will be conducted through this study, and it is the purpose of this study to be used as a material that can contribute to the creation of Chinese musical with evenly high workability and productability in the future.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.103-105
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• 2003

After fifteen years of development, Magnetic Resonance (MR) technology for human imaging and spectroscopy is reaching a refined state with FDA approved 3T clinical products from Siemens, GE, and Philips. Broker has cleared CE approval with a 4T system. Varian supports a 4T system platform as well. Shielded magnets are standard at 3T from GE, Oxford, Magnex, and IGC. A shielded 4T whole body magnet is available from Oxford. Stronger switched gradients and dynamic shim coils, desired at any field, areespecially useful at higher static magnetic fields B0. In addition to the higher currents required for higher resolution slice or volume selection afforded by higher SNR, whole body gradient coils will be driven at increasing slew rates to meet the needs of new cardiac applications and other requirements. For example 3T and 4T systems are now being equipped with 2kV, 500A gradient coils and amplifiers capable of generating 4G/cm in 200msec, over a 67+/-cm bore diameter. High field EPI applications require oscillation rates at 1 kHz and higher. To achieve a benchmark 0.2 ppm shim over a 30cm sphere in a high field magnet, at least four stages of shimming need to be considered. 1) A good high field magnet will be built to a homogeneity spec. falling in the range of 100 to 150 ppm over this 30cm spherical "sweet spot" 2) Most modern high field magnets will also have superconducting shim coils capable of finding 1.5 ppm by their adjustment during system installation. 3) Passive ferro-magnetic shimming combined with 4) active, high order room temperature shim coils (as many as five orders are now being recommended) will accomplish 0.2 ppm over the 30cm sphere, and 0.1 ppm over a human brain in even the highest field magnets for human studies. Safety concerns for strong, fast gradients at any B0 field include acoustic noise and peripheral nerve stimulation. One or more of the mechanical decoupling methods may lead to quieter gradients. Patient positioning relative to asymmetric or short gradient coils may limit peripheral nerve stimulation at higher slew rates. Gradient designs combining a short coil for local speed and strength with a longer coil for coverage are being developed for 3T systems. Local gradients give another approach to maximizing performance over a limited region while keeping within the physiologically imposed dB0/dt performance limits.

• Journal of the Society of Naval Architects of Korea
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• v.33 no.3
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• pp.35-47
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• 1996

A surface panel method treating a boundary-value problem of the Dirichlet type is presented to design a three dimensional body with free surface corresponding to a prescribed pressure distribution. An integral equation is derived from Green's theorem, giving a relation between total potential of known strength and the unknown local flux. Upon discretization, a system of linear simultaneous equations is formed including free surface boundary condition and is solved for an assumed geometry. The pseudo local flux, present due to the incorrect positioning of the assumed geometry, plays a role f the geometry corrector, with which the new geometry is computed for the next iteration. Sample designs for submerged spheroids and Wigley hull and carried out to demonstrate the stable convergence, the effectiveness and the robustness of the method. For the calculation of the wave resistance, normal dipoles and Rankine sources are distributed on the body surface and Rankine sources on the free surface. The free surface boundary condition is linearized with respect to the oncoming flow. Four-points upwind finite difference scheme is used to compute the free surface boundary condition. A hyperboloidal panel is adopted to represent the hull surface, which can compensate the defects of the low-order panel method. The design of a 5500TEU container carrier is performed with respect to reduction of the wave resistance. To reduce the wave resistance, calculated pressure on the hull surface is modified to have the lower fluctuation, and is applied as a Dirichlet type dynamic boundary condition on the hull surface. The designed hull form is verified to have the lower wave resistance than the initial one not only by computation but by experiment.

• Korea Trade Review
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• v.41 no.5
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• pp.63-87
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• 2016

Despite its rising labor costs these days, China still serves the role as 'World's Factory' thanks to a great deal of foreign direct investment, still remaining one of the world's highest, and the global companies, which have been willingly establishing foreign subsidiaries in China. While enjoying the benefits from the Chinese market, these global companies can now take advantages of another market; the one of Korea. If a product produced by a certain global company is actually manufactured in the local factory in China and the product meets specifications of Rules of Origin, the product shall receive preferential treatment under China-Korea FTA. In the perspective of global market, therefore, it is found that China-Korea FTA may have negative effects on chemical industry in Korea, which is considered one of the representatives of China-Korea FTA. This study examines such risks by network analysis, with several cases of 'Beauty or Make-up Preparations (HS Code 3304).' Analysis shows that Korea is classified as the marginal country group but not main country group when it comes to beauty products family. So this can be a great chance to the global cosmetic companies with local factories in China in the sense that they can increase their sales towards the market of Korea based on the China-Korea FTA. Under these concerns, this study suggests two policy alternatives for the chemical industry in Korea to deal with current challenges rising from China-Korea FTA. The suggested alternatives are: to actively attract the global chemical corporations which are yet to directly enter the Chinese market; and to invest on chemical products with high potential of growth as a priority.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.3
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• pp.51-58
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• 2006

The purpose of this research presents a method to position and makes the structure for eco-corridors reasonably with collectable analysing results of various effects shown in mammals' road-kill at 429 points. Target animals of this research are Leopard cat, Siberian weasel, Raccoon dog, Korean hare, Eurasian red squirrel, Siberian chipmunk and Water deer. The results derived from the empirical analysis on the contents above are followed. First, according to the results as for Leopard cat road kill analysis, which is designated as Endangered Species Class II, the eco-corridor might be located at near village having stead food in order to decrease the frequencies of road-kill, because its road kill points were mainly collected at 4 lane hilly road with mountain-road-farm area geological type of. Second, because Siberian weasel's road kill was detected at 2 lane hilly road with mountain-road-stream geological type, the eco-corridor might be located at near a mill to decrease road-kill frequencies. Third, the road-kill frequency of Eurasian red squirrel can be reduced when the eco-corridor is located at the area across coniferous tree near 4 lane west sea freeway with mountain-road-mountain. Fourth, the road-kill of Raccoon dog can be reduced when the eco-corridor is located at 4 lane mountain road or hilly road with the geological type having farm land-road-mountain(stream). Fifth, Korean hare's road-kill can be reduced when the eco-corridor is located at grass land across ridge line of mountain, because wild rabbit road kill was happened at 4 lane mountain road or 2 lane mountain road(mountain-road-mountain). Sixth, As for Siberian chipmunk, the eco-corridor might be located at the side slope of mountain road at 2 lane mountain road under the speed of 60km/h with mountain-road-mountain. Seventh, For Water deer, the eco-corridor might be located at 4 lane hilly road with mountain-road-farm land. As for Common otter, Amur hedgehog, Yellow-throated marten, Weasel, it is difficult to specify the proper site of eco-corridor due to the lack of data. Eco-corridors for carnivores might be well located at 4 lane hilly road or 2 lane hilly road with mountain-road-farm land, and the track for herbivores might be well located as a overhead bridge on mountain-road-mountain type across mountains. In order to position eco-corridors for wildlife properly, we have to research animal's behavior with ecological background, and to consider the local uniqueness and regularly collect the empirical road-kill data in long term 3 to 5 year, which can be the foundation for the more suitable place of wild life eco-corridors.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.427-436
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• 2016

Due to disasters such as earthquakes and landslides in urban areas, persons have been buried inside collapsed buildings and structures. Rescuers have mainly utilized detection equipment by applying sound, video and electric waves, but these are expensive and due to the directional approaches onto the collapsed site, secondary collapse risk can arise. In addition, due to poor utilization of such equipment, new human detection technology with quick and high reliability has not been utilized. To address these issues, this study develops a wireless signal-based human detection module that can be loaded into an Unmanned Aerial Vehicle (UAV). The human detection module searches for the 3D location for buried persons by collecting Wi-Fi signal and barometer sensors data transmitted from the mobile phones. This module can gain diverse information from mobile phones for buried persons in real time. We present a development framework of the module that provides 3D location data with more reliable information by delivering the collected data into a local computer in the ground. This study verified the application feasibility of the developed module in a real collapsed area. Therefore, it is expected that these results can be used as a core technology for the quick detection of buried persons' location and for relieving them after disasters that induce building collapses.