• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1243-1249
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• 2016

Background: Expression of p53, cyclin D1, p21 (WAF1) and Ki-67 (MIB1) was evaluated in oral squamous cell carcinoma (OSCC) to test whether levels of these markers at invasive tumour fronts (ITFs) could predict the development of local recurrence. Materials and Methods: Archived paraffin-embedded specimens from 51 patients with T1/T2 tumours were stained immunohistochemically and analysed quantitatively. Local recurrence-free survival was tested with Kaplan-Meier survival plots (log-rank test) using median values to define low and high expression groups and with a Cox's proportional hazards model in which the expression scores were entered as continuous variables. Results: The assessment of expression of all markers was highly reliable, univariate analysis showing that patients with clear surgical margins, with low cyclin D1 and high p21 expression at the ITF had the best local recurrence-free survival. Multivariate analysis showed that these three parameters were independent prognostic factors but that neither p53 nor MIB1 expression were of prognostic value. Conclusions: Assessment of p53, cyclin D1, p21 (WAF1), and Ki-67 (MIB1) at the ITF could help to predict local recurrence in early stage oral squamous cell carcinoma cases.

• Journal of the Korean Mathematical Society
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• v.44 no.1
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• pp.179-188
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• 2007

We prove the equivariant version of the semialgebraic local-triviality of semialgebraic maps.

• Journal of muscle and joint health
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• v.2 no.1
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• pp.73-86
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• 1995

Heat and cold often produce a similar clinical effect but different physiologic mechanisms. The purpose of this study was to compare the effects of local heat and cold therapy on joint pain, discomfort and, ROM of the arthritic knee joint. Thirty female subjects took Ice bag and hot bag with random assignment of initial therapy Subjects rated the degree of Joint pain and discomfort before and after each therapy, and then ROM was measured. The results of the study were as follows : 1. The hot bag group showed significantly lower joint pain & discomfort score than the ice bag group. ROM was increased in the hot bag group compared with subjects in the ice bag group. But there is not significant differences. 2. The ice bag group showed significantly lower joint pain score after than before therapy. But there are no significant differences in discomfort score & ROM between after & before therapy. 3. The hot bag group showed significantly lower joint pain, discomfort score after than before therapy. ROM was significantly increased after than before therapy in hot bag group. Therefore hot bag was significantly more effective than the ice bag in relieving the arthritic joint symptoms. A further study is necessary to determine the effect of local heat and cold therapy including the related variables such as preference for heat or cold.

• East Asian mathematical journal
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• v.17 no.2
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• pp.339-348
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• 2001

• Korean Journal of Ichthyology
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• v.18 no.4
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• pp.329-338
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• 2006

Phylogenetic relationships and DNA polymorphism among local populations of the Korean native catfish species, Liobagrus mediadiposalis, have been investigated based on mitochondrial cytochrome b DNA sequences. As a result, three genetically distinct groups of local populations were recognized based on the phylogenetic tree constructed. The first group was called "Nakdong-river group" that included the local populations from Geumho-river, Gyeongho-river, and Deokcheon-river; the second one was "Geum-river group"; the third one was represented as "Seomjin-river group" that included the samples from Seomjin-river, Dongjin-river and Geokum-do. The phylogeny also implied that the ancestral group of L. mediadiposalis have first evolved to Nakdong-river group, and later two local populations (Geum-river and Seomjinriver group) were diverged from the other lineage. DNA polymorphisms we observed were 4.4~4.7% between Geum-river group and Seomjin-river group, 5.1~5.5% between Seomjinriver group and Nakdong-river group, and 5.5~5.7% between Nakdong-river group and Geumriver group. These results indicated the long period of geographic isolation due to the river system in Korea caused such high degrees of DNA polymorphisms between local populations of L. mediadiposalis.

• Cartoon and Animation Studies
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• s.41
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• pp.153-168
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• 2015

In Kyung-GI DO, An-sung, Each local autonomous entity developed the character design to inform the public relations and revitalize local economy and culture. consequently, These have got benefits with marketing local speciality related to their an-sung character; we call it name is arum, pung-mul, duck-bugi who korea traditional face characters. On the contrary, Most of old characters which have been fallen off their formative qualities became a reason that unfit (4D,3D) special film at local doom movie theater. This thesis aims to study on the character of 'namsadang' group what have been produced in ansung-si, that the show up to people about an-sung 4D Contents what local actually character and to make it more competitive through 3D,4D spacial character project developing process. It is need for new various characters, that (3D,4D-VFX) -Graphics of new an-sung'namsadang' group. that will be total different and new development. total VFX; 4-Dimantion visual graphics released in next an-sung local festival, Business prospects are bright and receiving benefits are increasing. As seen in the case of the character of in 2015, it can be a measure to earn benefits as a higher value-added business if it is managed in the local autonomous entities. In this thesis, I propose what the of character in the local special graphics; VFX style characters design. also I was show up to '4D contents character;' ; 'namsadang' group; creative processing including planing. It is possible to be ranged from special 4D series animation, a feature-length special effct cartoon film, character products, and even local doom Theme parks show up film. which are all expected high profits. These profits will be returned back to the an-sung local autonomous entity, who can use them to develop new contents, one of foundations in local economy. As a result, it is helpful to make local traits and effective tourist attractions.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.51.2-51.2
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• 2014

Ultra faint dwarf galaxies (UFDs) are larger but fainter than globular clusters, being the faintest galaxies in the universe. They have been found only in the Local Group. We report the discovery of an UFD in the intracluster field of the Virgo cluster (Virgo UFD1). It is located near the core of Virgo cluster, and far from any massive galaxies. The color magnitude diagram of resolved stars in Virgo UFD1 shows narrow, metal poor red giant branch (RGB), which is very similar to the UFDs in the Local Group. by comparing RGB in this galaxy with 12 Gyr stellar isochrones, we estimate its distance, $d=16.4{\pm}0.4$ Mpc and mean metallicity, $[Fe/H]=-2.4{\pm}0.4$. We derive its integrated photometric properties and structural parameters : V-band absolute magnitude of $MV=-6.3{\pm}0.2$, effective radius of $84{\pm}7pc$, and central surface brightness of ${\mu}V,0=26.49{\pm}0.09$ mag arcsec-2. These properties are similar to these of Local Group UFDs. Virgo UFD1 is the first UFD discovered beyond the Local Group. These results indicate that it may be a fossil remnant of the first galaxies.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.14 no.2
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• pp.173-180
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• 2007

Purpose: The present study was done to examine the effect of music therapy on anxiety and pain in patients for whom a ureteral stent was inserted under local anesthesia. Method: The participants in this study were 22 patients who received a ureteral stent at the Day Surgery Center of C University Hospital during the period from May to October in 2006. The patients were divided into a control group (n=11) and an experimental group (n=11). For the experimental group, music was played according to their musical preference using headphones. The music was provided from the point when the patient took the posture for the operation and was covered with a sterilized drape to the point when the cystoscope was removed after finishing the operation. The control group was only provided with ordinary nursing services. Results: The results show that the provision of music therapy to these patients is effective in reducing the patients' salivary cortisol and Vas-anxiety score and stabilizing their systolic blood pressure. Conclusion: We conclude that music therapy can be actively used as a nursing intervention for reducing anxiety in patients who receive operations under local anesthesia.

• The Korean Journal of Pain
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• v.8 no.1
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• pp.60-64
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• 1995

Stellate ganglion block is a selective sympathetic blockade affecting the head and neck, and the upper extemity. It is an important method which has been used most frequently in neuro-pain clinic due to its wide range of indications. The authors attermpted to define the minimal volume of local anesthetic which need for successful stellate ganglion block by using 1% mepivacaine HCl mixed with dye. In 40 heathy volunteers, two different volumes, 3 ml in the group 1 (n=20) and 4 ml in the group 2 (n=20), were injected by an anterior paratracheal technique at the sixth cervical vertebral level. We compared the degree in sympathetic blockade by clinical sings and symptoms and also checked the spread range of dye by plain X-ray. With seven criteria for an effective block. mean score was 5.7 in group 2, while 3.4 in group 1. These results suggest that 4 ml of local anesthetic are adequate for a successful stellate ganglion block.

• Journal of Dental Anesthesia and Pain Medicine
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• v.20 no.3
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• pp.119-127
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• 2020

This study was conducted to determine how precooling reduces the subjective reported pain and objective pain and to evaluate the effectiveness of precooling the injection site before administration of local anesthesia in children. Electronic databases (PubMed, Ovid SP, Cochrane Central Register of Controlled Trials) were searched for publications from 1980 to 2020. Studies were screened for titles and abstracts, followed by full-text evaluation of included reports. Six studies were included in this systematic review. The primary outcome evaluated was the pain perception or the subjective pain reported by the child receiving the injection. The secondary outcome evaluated was objective pain evaluated in each study. Among 5 studies that evaluated child reported pain scores on a visual analogue scale (VAS), 4 studies reported lower scores in the precooling group and one study reported a higher VAS score in the precooling group than in children treated with 20% benzocaine topical anesthesia. Among 6 studies that evaluated the pain reaction of children by Sound Eye Motor (SEM) score, 4 studies reported a lower SEM score in the precooling group, one study reported no significant difference between the precooling and control groups, and one study reported higher SEM scores in the precooling group than in children treated with 20% benzocaine topical anesthesia. Within the limits of this systematic review, evidence suggests that precooling the injection site with ice can be an effective adjunct to topical anesthesia in reducing both subjective and objective pain during local anesthesia administration in children.