• 한국균학회지
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• 제29권1호
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• pp.47-51
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• 2001

SD계 랫트를 사용하여 6주 동안 탄수화물 대용으로 50% 및 100%의 Lentinus tuber-regium(LTR)-첨가 투여그룹의 비만 및 지질대사에 미치는 영향을 평가하였다. LTR-50 및 LTR-100 투여그룹의 체중 증가는 대조그룹 대비 각각 3.2%, 29.3%의 억제효과로 나타났는데도 사료 섭취량은 대조그룹 대비 오히려 24.5% 및 40,7%나 증가했다. 이들 LTR-첨가사료의 사료효율이 대조그룹 대비 22% 및 50%나 현저히 감소했는데도 불구하고 에너지효율은 이와는 반대로 두 그룹 모두 약 10%의 GE 증가효과가 인정되었다. LTR-50 및 LTR-100 투여그룹의 대사체중에 대한 사료 섭취량의 비(DI/MBS ratio)는 대조그룹 대비 50.3% 및 136.1%나 매우 유의적인 증가현상이 인정되었다. LTR-50 및 LTR-100 투여그룹은 대조그룹 대비 22.4% 및 32.6%나 현저한 TG 함량의 억제효과가 인정되었고 이들 LTR 투여그룹은 대조그룹 대비 8.3% 및 12.7%나 유의적인 LDL-콜레스테롤의 혈관축적 억제효과가 인정되었다. 이들 LTR투여그룹은 대조그룹 대비 $3{\sim}$10%의 효과적인 HDL-콜레스테롤의 생성효과가 인정되었다. 또한 이들 LTR 투여그룹의 동맥경화지수(Al) 는 대조그룹 대비 $8{\sim}13%$의 상당히 유의적인 Al의 감소효과가 인정되었다. 이상의 결과를 종합해 볼 때 탄수화물 대용으로 LTR의 50%이상 투여에서는 비만을 매우 효과적으로 억제할 수 있을 뿐만 아니라 LTD의 50%이하 부여에서는 가축의 대체사료 개발에 기여할 수 있을 것으로 기대된다. 또한 이들 LTR-첨가사료는 TG, LDL-콜레스테롤 및 동맥경화지수(Al)의 감소, 그리고 HDL-콜레스텔롤의 증가 때문에 성인병을 매우 효과적으로 억제할 수 있을 것으로 기대된다.

• 한국정밀공학회지
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• 제21권2호
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• pp.67-73
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• 2004

Some of Spacecraft's structures are flexible so that a certain expected disturbance can easily excite a low frequency vibration on these structures, having very low natural damping. Such vibration will degrade the performance of the system, which should to be kept in a specific shape or attitude against the undesired vibration. In this paper, LQG/LTR controller is developed using an additional dynamic model to increase the performance of the frequency responses at low frequency area. This study presents that the LQG/LTR design was an effective controller for the flexible structure.

• 대한기계학회논문집
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• 제15권5호
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• pp.1620-1634
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• 1991

본 연구에서는 전기/자기 및 기계적 요소들이 복합되어 이루어진 자기부상 시 스템의 설현을 위한 기초단계로서 제어동역학(controlled dynamics) 측면에 입각한 모 델식을 본드선도 기법을 이용하여 보다 조직적으로 유도한다. 우선, 자속흐름 확장 및 자속 유출량을 고려하여 부상 시스템을 모델링하고 차량/레일 및 2차 현가(second ary suspension)장치를 포함한 자기부상 시스템을 모델링한다. 다음, 지지 및 안내 방향의 동역학을 동시에 고려한 2차원 자기부상 시스템을 본드선도의 다접점 필드(mu- ltiport field) 개념을 이용하여 모델링한다. 끝으로, 본드선도 기법으로 모델링된 2차원 자기부상 시스템의 안정도와 성능을 향상시키기 위하여 LOG/LTR(linear quadra- tic Gaussian control with loop transfer recovery) 제어시스템을 설계한다. LQG/ LTR 제어방법은 Doyle과 Stein에 의해 인성(stability-robustness) 문제와 주파수역 성능을 설계시에 직접 고려할 수 있는 강력한 선형 다변수 제어시스템 설곕방법으로 현재 널리 사용되고 있다.

• 한국정밀공학회지
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• 제7권1호
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• pp.74-85
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• 1990

The LQG and LQG/LTR compensators have the same structrues in dynamics. The only difference is the values of the design parameters in the two compensators. The design parameters of the LQG and LQG/LTR compensators are selected in the sense of the least-squares error minimi- zation and loop shaping, respectively. In this paper, the LQG and LQG/ LTR design methods are applied to the helicopter in hover which is modeled as a SISO fourth order system. The dynamic characteristics and the perfor- mance of the two control systems are analyzed by the computer simulation. It is found that the LQG/LTR design method is systematic and has good performance in comparision with the LQG design method.

• 제어로봇시스템학회논문지
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• 제6권5호
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• pp.356-366
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• 2000

In this paper, a nonlinear $H_2/H_\infty/LTR$ control for the flexible inverted pendulum of a parallel type with Coulomb friction is presented. The dynamic equation for this system is derived by the Hamilton's principle and assumed-mode method. This hard nonlinear system can be modeled by a the quasi-linear state space model using the REF method. It is shown that the $H_2/H_\infty$ control can be applied to the nonlinear controller design of the system having Coulomb frictions if the proper LTR conditions are satisfied. In order to present the usefulness of the suggested control method, the nonlinear $H_2/H_\infty/LTR$ controller is designed to control the Position of the end point of the flexible inverted pendulum that has Coulomb frictions present in actuator parts. The results are given via computer simulations.

• 대한기계학회논문집
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• 제17권11호
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• pp.2730-2741
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• 1993

A mathematical model of the seeker scan-loop which is composed of a spin-stabilized gyroscope and its driving signal processors is derived. The derived model has a transmission zero pair on the imaginary axis near to the required bandwidth. The LQG/LTR design methodology is evolved for the derived scan-loop model. To implement the designed LQG/LTR compensator to the actual plant, the compensator order is reduced using the internally balanced realization method. The performances of the LQG/LTR compensator are tested and compared with those of the P-control. Especially, stability-robustnessexperiments for model uncertainties represented in the form of time-delays are performed. It is demonstrated that the LQG/STR compensator is actually very robust to model uncertainties.

• 대한전기학회논문지:전력기술부문A
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• 제48권8호
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• pp.965-971
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• 1999

This paper presented to design the power system stabilizer(PSS) for a turbo-generator system using LQG/LTR control synthesis for improving small-signal stability. Application study of LGG/LTR control synthesis is more appropriate in this system since a turbo-generator system is usually operated under circumstance of unmeasurable uncertainties and external disturbance. The LQG/LTR control theory was briefly reviewed for good understanding and the reasonable design approach. The design results are simulated for a case study and to check the system performance in comparison with currently operating lead-lag filtered PSS performance.

• Journal of Ginseng Research
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• 제35권4호
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• pp.413-420
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• 2011

We investigated whether Korean red ginseng (KRG) and highly active antiretroviral therapy (HAART) affect the frequency of gross deletion in 5'LTR/gag in 20 hemophiliacs. This study is a prospective study in 20 hemophiliacs who were infected with Korean subclade B of HIV-1 from two cash-paid plasma donors in 1990. Over a 13-year period, we obtained 436 amplicons of 5'LTR/gag genes by nested polymerase chain reaction using 147 peripheral blood mononuclear cells. Of the 436 amplicons, 92 (21.1%) showed gross deletion in 5'LTR/gag. Despite of a 2.3-fold higher monthly dose of KRG intake, the frequency of gross deletion in 5'LTR/gag (16.4%) was significantly decreased during HAART compared with 28.1% prior to HAART (p<0.01). Gross deletion in 5'LTR/gag was 10% more detected on KRG-therapy than prior to KRG-therapy (p<0.05). In addition, we also obtained 28 amplicons containing premature stop codon or isoleucine at initiation codon of 254 amplicons sequenced on KRG intake (7.5%) or HAART (13.6%) compared with 0% before KRG intake. These findings indicate that high frequency of gross deletion in 5'LTR/gag and genetic defects prior to HAART are significantly associated with KRG intake and the detection of gross deletion in 5'LTR/gag is decreased by HAART.

• Animal cells and systems
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• 제5권3호
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• pp.243-246
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• 2001

Human endoqenous retroviral long terminal repeats (LTRs) have been found to be coexpressed with sequences of genes closely located nearby. It has been suggested that the LTR elements have contributed to structural changes or genetic variations of human genome connected to various diseases and evolution. Using cDNA library derived from placenta tissue, we performed PCR amplification and identified five new HERV-W LTR elements. Those LTR elements showed a high degree of sequence similarity (98-99%) with HERV-W LTR (AF072500). A phylogenetic tree obtained by the neighbor-joining method revealed that HERV-W LTR elements could be mainly divided into two groups through evolutionary divergence. Five new HERV-W LTR elements (pla-1, 4, 5, 6, 7) belonged to the group I with AX000960, AF072504, and AF072506 from GenBank database. The data suggest that several copy numbers of the HERV-W LTR elements are transcribed in placenta and may contribute to the understanding of biological function such as human placental morphogenesis.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1993년도 한국자동제어학술회의논문집(국제학술편); Seoul National University, Seoul; 20-22 Oct. 1993
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• pp.88-94
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• 1993

In this paper we analyze the RHLQG/FIRF optimal.contol law presented in [4,5] in order to stabilizes a stochastic linear time varying systems with modeling uncertainty. It is shown by the frequency domain analysis that the RHC is robuster than the LQ control law. Explicit LTR procedures are given to improve the robust performance of RHLQC/FIRF cotrol law. Using the mismatching function technique [8], we propose an LTR method which makes the RHLQG/FIRF controller recover the feedback properties of the R.HC law. Also we compare the LTR performance of the RHLQC/FIRF via simulation with conventional LTR methods.